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There are 20769 results for: content related to: Cell Cycle and Growth Control: Current Clinical Applications

  1. You have free access to this content
    Flavopiridol inhibits lipopolysaccharide-induced TNF-α production through inactivation of nuclear factor-κB and mitogen-activated protein kinases in the MyD88-dependent pathway

    Microbiology and Immunology

    Volume 55, Issue 3, March 2011, Pages: 160–167, Abedul Haque, Naoki Koide, Imtiaz Iftakhar-E-Khuda, Abu Shadat Mohammod Noman, Erdenezaya Odkhuu, Battuvshin Badamtseren, Yoshikazu Naiki, Takayuki Komatsu, Tomoaki Yoshida and Takashi Yokochi

    Version of Record online : 23 FEB 2011, DOI: 10.1111/j.1348-0421.2010.00304.x

  2. Cell Cycle Control

    Targeting Protein Kinases for Cancer Therapy

    David J. Matthews, Mary E. Gerritsen, Pages: 327–390, 2010

    Published Online : 11 MAR 2010, DOI: 10.1002/9780470555293.ch6

  3. Intracellular Signaling Kinase Inhibitors

    Targeting Protein Kinases for Cancer Therapy

    David J. Matthews, Mary E. Gerritsen, Pages: 567–621, 2010

    Published Online : 11 MAR 2010, DOI: 10.1002/9780470555293.ch10

  4. You have free access to this content
    Characterization of molecular and cellular functions of the cyclin-dependent kinase CDK9 using a novel specific inhibitor

    British Journal of Pharmacology

    Volume 171, Issue 1, January 2014, Pages: 55–68, T K Albert, C Rigault, J Eickhoff, K Baumgart, C Antrecht, B Klebl, G Mittler and M Meisterernst

    Version of Record online : 10 DEC 2013, DOI: 10.1111/bph.12408

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    Cell cycle-independent induction of apoptosis by the anti-tumor drug flavopiridol in endothelial cells

    International Journal of Cancer

    Volume 77, Issue 1, 3 July 1998, Pages: 146–152, Sabine Brüsselbach, Dirk M. Nettelbeck, Hans-Harald Sedlacek and Rolf Müller

    Version of Record online : 6 DEC 1998, DOI: 10.1002/(SICI)1097-0215(19980703)77:1<146::AID-IJC22>3.0.CO;2-B

  6. You have free access to this content
    Identification of cytosolic aldehyde dehydrogenase 1 from non-small cell lung carcinomas as a flavopiridol-binding protein

    FEBS Letters

    Volume 454, Issue 1-2, July 02, 1999, Pages: 100–104, Joachim B. Schnier, Gurmet Kaur, Astrid Kaiser, Sherman F. Stinson, Edward A. Sausville, John Gardner, Kayoko Nishi, E.Morton Bradbury and Adrian M. Senderowicz

    Version of Record online : 6 JUL 1999, DOI: 10.1016/S0014-5793(99)00773-5

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    Reduced occurrence of tumor flare with flavopiridol followed by combined flavopiridol and lenalidomide in patients with relapsed chronic lymphocytic leukemia (CLL)

    American Journal of Hematology

    Volume 90, Issue 4, April 2015, Pages: 327–333, Kami Maddocks, Lai Wei, Darlene Rozewski, Yao Jiang, Yuan Zhao, Mikhil Adusumilli, William E. Pierceall, Camille Doykin, Michael H. Cardone, Jeffrey A. Jones, Joseph Flynn, Leslie A. Andritsos, Michael R. Grever, John C. Byrd, Amy J. Johnson, Mitch A. Phelps and Kristie A Blum

    Version of Record online : 25 FEB 2015, DOI: 10.1002/ajh.23946

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    The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

    The EMBO Journal

    Volume 27, Issue 13, July 9, 2008, Pages: 1907–1918, Sonja Baumli, Graziano Lolli, Edward D Lowe, Sonia Troiani, Luisa Rusconi, Alex N Bullock, Judit É Debreczeni, Stefan Knapp and Louise N Johnson

    Version of Record online : 19 JUN 2008, DOI: 10.1038/emboj.2008.121

  9. Potential Clinical Uses of CDK Inhibitors: Lessons from Synthetic Lethality Screens

    Medicinal Research Reviews

    Volume 35, Issue 6, November 2015, Pages: 1156–1174, Ladislava Vymětalová and Vladimír Kryštof

    Version of Record online : 25 JUN 2015, DOI: 10.1002/med.21354

  10. T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes

    Journal of Cellular Physiology

    Volume 224, Issue 1, July 2010, Pages: 84–93, Eugene C. Dow, Hongbing Liu and Andrew P. Rice

    Version of Record online : 3 MAR 2010, DOI: 10.1002/jcp.22096

  11. Flavopiridol as a radio-sensitizer for esophageal cancer cell lines

    Diseases of the Esophagus

    Volume 17, Issue 4, December 2004, Pages: 338–344, S. Sato, Y. Kajiyama, M. Sugano, Y. Iwanuma and M. Tsurumaru

    Version of Record online : 24 NOV 2004, DOI: 10.1111/j.1442-2050.2004.00437.x

  12. You have free access to this content
    CDKI-71, a novel CDK9 inhibitor, is preferentially cytotoxic to cancer cells compared to flavopiridol

    International Journal of Cancer

    Volume 130, Issue 5, 1 March 2012, Pages: 1216–1226, Xiangrui Liu, Shenhua Shi, Frankie Lam, Chris Pepper, Peter M. Fischer and Shudong Wang

    Version of Record online : 21 JUN 2011, DOI: 10.1002/ijc.26127

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    Investigation of the cytotoxic effect of flavopiridol in canine lymphoma cell lines

    Veterinary and Comparative Oncology

    Volume 14, Issue S1, August 2016, Pages: 95–106, Y. Ema, M. Igase, Y. Takeda, T. Yanase, S. Umeki, H. Hiraoka, M. Okuda and T. Mizuno

    Version of Record online : 26 JAN 2015, DOI: 10.1111/vco.12130

  14. A high-performance liquid chromatography method using ultraviolet detection for the quantitation of flavopiridol from human plasma

    Biomedical Chromatography

    Volume 16, Issue 6, September 2002, Pages: 379–382, Suoping Zhai, Edward Sausville and William D. Figg

    Version of Record online : 10 APR 2002, DOI: 10.1002/bmc.166

  15. You have full text access to this Open Access content
    Cyclin-dependent kinase 1 inhibitor RO-3306 enhances p53-mediated Bax activation and mitochondrial apoptosis in AML

    Cancer Science

    Volume 100, Issue 6, June 2009, Pages: 1128–1136, Kensuke Kojima, Masaya Shimanuki, Masato Shikami, Michael Andreeff and Hideki Nakakuma

    Version of Record online : 10 MAR 2009, DOI: 10.1111/j.1349-7006.2009.01150.x

  16. Initial testing (stage 1) of the cyclin dependent kinase inhibitor SCH 727965 (dinaciclib) by the pediatric preclinical testing program

    Pediatric Blood & Cancer

    Volume 59, Issue 7, 15 December 2012, Pages: 1266–1274, Richard Gorlick, E. Anders Kolb, Peter J. Houghton, Christopher L. Morton, Geoffrey Neale, Stephen T. Keir, Hernan Carol, Richard Lock, Doris Phelps, Min H. Kang, C. Patrick Reynolds, John M. Maris, Catherine Billups and Malcolm A. Smith

    Version of Record online : 7 FEB 2012, DOI: 10.1002/pbc.24073

  17. Preclinical study of treatment response in HCT-116 cells and xenografts with 1H-decoupled 31P MRS

    NMR in Biomedicine

    Volume 24, Issue 9, November 2011, Pages: 1159–1168, Moses M. Darpolor, Peter T. Kennealey, H. Carl Le, Kristen L. Zakian, Ellen Ackerstaff, Asif Rizwan, Jin-Hong Chen, Elliot B. Sambol, Gary K. Schwartz, Samuel Singer and Jason A. Koutcher

    Version of Record online : 24 MAR 2011, DOI: 10.1002/nbm.1674

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    Delayed combinatorial treatment with flavopiridol and minocycline provides longer term protection for neuronal soma but not dendrites following global ischemia

    Journal of Neurochemistry

    Volume 105, Issue 3, May 2008, Pages: 703–713, Grace O. Iyirhiaro, Tyson B. Brust, Juliet Rashidian, Zohreh Galehdar, Aweis Osman, Maryam Phillips, Ruth S. Slack, Brian A. MacVicar and David S. Park

    Version of Record online : 6 DEC 2007, DOI: 10.1111/j.1471-4159.2007.05166.x

  19. Inhibition of P-TEFb disrupts global transcription, oocyte maturation, and embryo development in the mouse

    genesis

    Volume 54, Issue 9, September 2016, Pages: 470–482, Reza K. Oqani, Tao Lin, Jae Eun Lee, So Yeon Kim, Soo Jin Sa, Je Seok Woo and Dong Il Jin

    Version of Record online : 18 AUG 2016, DOI: 10.1002/dvg.22961

  20. You have free access to this content
    Cyclin-dependent kinase inhibitor, flavopiridol, induces apoptosis and inhibits tumor growth in drug-resistant osteosarcoma and Ewing's family tumor cells

    International Journal of Cancer

    Volume 121, Issue 6, 15 September 2007, Pages: 1212–1218, Yan Li, Kazuhiro Tanaka, Xu Li, Takamitsu Okada, Tomoyuki Nakamura, Minoru Takasaki, Shunsaku Yamamoto, Yoshinao Oda, Masazumi Tsuneyoshi and Yukihide Iwamoto

    Version of Record online : 22 MAY 2007, DOI: 10.1002/ijc.22820