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There are 1526 results for: content related to: Carboxylesterases: Overview, Structure, Function, and Polymorphism

  1. Carboxylesterases

    Standard Article

    Encyclopedia of Drug Metabolism and Interactions

    Bingfang Yan

    Published Online : 31 JAN 2012, DOI: 10.1002/9780470921920.edm014

  2. The Role of Human Carboxylesterases in Drug Metabolism: Have We Overlooked Their Importance?

    Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

    Volume 33, Issue 2, February 2013, Pages: 210–222, S. Casey Laizure, Vanessa Herring, Zheyi Hu, Kevin Witbrodt and Robert B. Parker

    Article first published online : 5 FEB 2013, DOI: 10.1002/phar.1194

  3. Hydrolytic Enzymes

    Metabolism of Drugs and Other Xenobiotics

    Pavel Anzenbacher, Ulrich M. Zanger, Pages: 165–198, 2012

    Published Online : 4 JUN 2012, DOI: 10.1002/9783527630905.ch6

  4. Prodrugs: Strategic Deployment, Metabolic Considerations, and Chemical Design Principles

    Standard Article

    Burger's Medicinal Chemistry and Drug Discovery

    Paul W. Erhardt, Rahul Khupse, Jeffrey G. Sarver and Jill A. Trendel

    Published Online : 15 APR 2010, DOI: 10.1002/0471266949.bmc157

  5. You have free access to this content
    Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin

    British Journal of Pharmacology

    Volume 160, Issue 8, August 2010, Pages: 1916–1928, MJ Hatfield, L Tsurkan, JL Hyatt, X Yu, CC Edwards, LD Hicks, RM Wadkins and PM Potter

    Article first published online : 1 MAR 2010, DOI: 10.1111/j.1476-5381.2010.00700.x

  6. Baboon carboxylesterases 1 and 2: sequences, structures and phylogenetic relationships with human and other primate carboxylesterases

    Journal of Medical Primatology

    Volume 38, Issue 1, February 2009, Pages: 27–38, Roger S. Holmes, Jeremy P. Glenn, John L. VandeBerg and Laura A. Cox

    Article first published online : 23 OCT 2008, DOI: 10.1111/j.1600-0684.2008.00315.x

  7. Carboxylesterases in the Metabolism and Toxicity of Pesticides

    Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology

    Colin J. Jackson, John G. Oakeshott, Juan C. Sanchez-Hernandez, Craig E. Wheelock, Pages: 57–75, 2011

    Published Online : 28 MAR 2011, DOI: 10.1002/9780470640500.ch5

  8. Allosteric kinetics of human carboxylesterase 1: Species differences and interindividual variability

    Journal of Pharmaceutical Sciences

    Volume 97, Issue 12, December 2008, Pages: 5434–5445, Shiori Takahashi, Miki Katoh, Takashi Saitoh, Miki Nakajima and Tsuyoshi Yokoi

    Article first published online : 27 MAR 2008, DOI: 10.1002/jps.21376

  9. Mechanisms of Drug Metabolism

    Standard Article

    Encyclopedia of Drug Metabolism and Interactions

    Robert S. Foti, Dan A. Rock, Larry C. Wienkers and Jan L. Wahlstrom

    Published Online : 15 OCT 2012, DOI: 10.1002/9780470921920.edm027

  10. Enzymes involved in the bioconversion of ester-based prodrugs

    Journal of Pharmaceutical Sciences

    Volume 95, Issue 6, June 2006, Pages: 1177–1195, Bianca M. Liederer and Ronald T. Borchardt

    Article first published online : 25 APR 2006, DOI: 10.1002/jps.20542

  11. Clopidogrel Bioactivation and Risk of Bleeding in Patients Cotreated With Angiotensin-Converting Enzyme Inhibitors After Myocardial Infarction: A Proof-of-Concept Study

    Clinical Pharmacology & Therapeutics

    Volume 96, Issue 6, December 2014, Pages: 713–722, K E Kristensen, H-J Zhu, X Wang, G H Gislason, C Torp-Pedersen, H B Rasmussen, J S Markowitz and P R Hansen

    Article first published online : 15 SEP 2014, DOI: 10.1038/clpt.2014.183

  12. Carboxylesterase 1 c.428G>A single nucleotide variation increases the antiplatelet effects of clopidogrel by reducing its hydrolysis in humans

    Clinical Pharmacology & Therapeutics

    Volume 97, Issue 6, June 2015, Pages: 650–658, EK Tarkiainen, MT Holmberg, A Tornio, M Neuvonen, PJ Neuvonen, JT Backman and M Niemi

    Article first published online : 9 MAY 2015, DOI: 10.1002/cpt.101

  13. Synthetic cannabimimetic agents metabolized by carboxylesterases

    Drug Testing and Analysis

    Ragnar Thomsen, Line M. Nielsen, Niels B. Holm, Henrik B. Rasmussen, Kristian Linnet and the INDICES Consortium

    Article first published online : 24 OCT 2014, DOI: 10.1002/dta.1731

  14. Soft Drugs

    Retrometabolic Drug Design and Targeting

    Nicholas Bodor, Peter Buchwald, Pages: 77–258, 2012

    Published Online : 9 OCT 2012, DOI: 10.1002/9781118407738.ch5

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    Identification of microsomal rat liver carboxylesterases and their activity with retinyl palmitate

    European Journal of Biochemistry

    Volume 269, Issue 18, September 2002, Pages: 4387–4398, Sonal P. Sanghani, Wilhelmina I. Davis, Natividad G. Dumaual, Alan Mahrenholz and William F. Bosron

    Article first published online : 29 AUG 2002, DOI: 10.1046/j.1432-1033.2002.03121.x

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    Regulation of carboxylesterase-2 expression by p53 family proteins and enhanced anti-cancer activities among 5-fluorouracil, irinotecan and doxazolidine prodrug

    British Journal of Pharmacology

    Volume 168, Issue 8, April 2013, Pages: 1989–1999, Da Xiao, Dongfang Yang, Liangran Guo, Wei Lu, Margaret Charpentier and Bingfang Yan

    Article first published online : 25 MAR 2013, DOI: 10.1111/bph.12125

  17. Design of Fexofenadine Prodrugs Based on Tissue-Specific Esterase Activity and Their Dissimilar Recognition by P-Glycoprotein

    Journal of Pharmaceutical Sciences

    Kayoko Ohura, Yuichiro Nakada, Shunsuke Kotani and Teruko Imai

    Article first published online : 7 MAY 2015, DOI: 10.1002/jps.24467

  18. Liver prenylated methylated protein methyl esterase is the same enzyme as sus scrofa carboxylesterase

    Journal of Biochemical and Molecular Toxicology

    Volume 22, Issue 1, February 2008, Pages: 51–62, Onovughode T. Oboh and Nazarius S. Lamango

    Article first published online : 13 FEB 2008, DOI: 10.1002/jbt.20214

  19. Species difference of esterase expression and hydrolase activity in plasma

    Journal of Pharmaceutical Sciences

    Volume 101, Issue 10, October 2012, Pages: 3979–3988, Fatma Goksin Bahar, Kayoko Ohura, Takuo Ogihara and Teruko Imai

    Article first published online : 25 JUL 2012, DOI: 10.1002/jps.23258

  20. Enzymatic stability of 2′-ethylcarbonate-linked paclitaxel in serum and conversion to paclitaxel by rabbit liver carboxylesterase for use in prodrug/enzyme therapy

    Biopharmaceutics & Drug Disposition

    Volume 29, Issue 5, July 2008, Pages: 259–269, Tadatoshi Tanino, Akihiro Nawa, Yasuyoshi Miki and Masahiro Iwaki

    Article first published online : 22 MAY 2008, DOI: 10.1002/bdd.611