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There are 8257190 results for: content related to: The Pyramid™ Approach to Fragment-Based Biophysical Screening

  1. Hit and Lead Identification from Fragments

    De novo Molecular Design

    Michael Mazanetz, Richard Law, Mark Whittaker, Pages: 143–200, 2013

    Published Online : 11 OCT 2013, DOI: 10.1002/9783527677016.ch6

  2. Cheminformatics Approaches to Fragment-based Lead Discovery

    Fragment-based Approaches in Drug Discovery

    Tudor I. Oprea, Jeffrey M. Blaney, Pages: 89–111, 2006

    Published Online : 28 AUG 2006, DOI: 10.1002/3527608761.ch5

  3. Practical Aspects of Using NMR in Fragment-Based Screening

    Fragment-Based Drug Discovery: A Practical Approach

    Edward R. Zartler, Michael J. Shapiro, Pages: 63–98, 2008

    Published Online : 27 OCT 2008, DOI: 10.1002/9780470721551.ch4

  4. The Synthesis of Biophysical Methods In Support of Robust Fragment-Based Lead Discovery

    Fragment-based Drug Discovery Lessons and Outlook

    Ben J. Davis, Anthony M. Giannetti, Pages: 119–138, 2016

    Published Online : 8 JAN 2016, DOI: 10.1002/9783527683604.ch06

  5. Fragment library design considerations

    Wiley Interdisciplinary Reviews: Computational Molecular Science

    Volume 2, Issue 6, November/December 2012, Pages: 868–885, Susan M. Boyd, Andrew P. Turnbull and Björn Walse

    Version of Record online : 6 JUN 2012, DOI: 10.1002/wcms.1098

  6. Fragment Based MS/MS Quantification

    Computational and Statistical Methods for Protein Quantification by Mass Spectrometry

    Ingvar Eidhammer, Harald Barsnes, Geir Egil Eide, Lennart Martens, Pages: 155–159, 2013

    Published Online : 10 JAN 2013, DOI: 10.1002/9781118494042.ch11

  7. Designing a Fragment Process to Fit Your Needs

    Fragment-Based Drug Discovery: A Practical Approach

    Edward R. Zartler, Michael J. Shapiro, Pages: 15–37, 2008

    Published Online : 27 OCT 2008, DOI: 10.1002/9780470721551.ch2

  8. Fragment-Based Approaches for Identification of BACE Inhibitors

    BACE: Lead Target for Orchestrated Therapy of Alzheimer's Disease

    Andreas Kuglstatter, Michael Hennig, Pages: 107–121, 2010

    Published Online : 26 MAR 2010, DOI: 10.1002/9780470594087.ch5

  9. Fragment-Based Drug Discovery of Kinase Inhibitors

    Kinase Inhibitor Drugs

    Rongshi Li, Jeffrey A. Stafford, Pages: 461–483, 2009

    Published Online : 28 SEP 2009, DOI: 10.1002/9780470524961.ch18

  10. Introduction to Fragment-Based Drug Discovery

    Fragment-Based Drug Discovery: A Practical Approach

    Mike Cherry, Tim Mitchell, Pages: 1–13, 2008

    Published Online : 27 OCT 2008, DOI: 10.1002/9780470721551.ch1

  11. Fragment-based Lead Discovery and Optimization Using X-Ray Crystallography, Computational Chemistry, and High-throughput Organic Synthesis

    Fragment-based Approaches in Drug Discovery

    Jeff Blaney, Vicki Nienaber, Stephen K. Burley, Pages: 215–248, 2006

    Published Online : 28 AUG 2006, DOI: 10.1002/3527608761.ch11

  12. The Concept of Fragment-based Drug Discovery

    Fragment-based Approaches in Drug Discovery

    Daniel A. Erlanson, Wolfgang Jahnke, Pages: 1–10, 2006

    Published Online : 28 AUG 2006, DOI: 10.1002/3527608761.ch1

  13. Pyramid: An Integrated Platform for Fragment-based Drug Discovery

    Fragment-based Approaches in Drug Discovery

    Thomas G. Davies, Rob L. M. van Montfort, Glyn Williams, Harren Jhoti, Pages: 193–214, 2006

    Published Online : 28 AUG 2006, DOI: 10.1002/3527608761.ch10

  14. NMR-guided Fragment Assembly

    Fragment-based Approaches in Drug Discovery

    Wolfgang Jahnke, Daniel A. Erlanson, Pages: 147–180, 2006

    Published Online : 28 AUG 2006, DOI: 10.1002/3527608761.ch8

  15. Assembling a Fragment Library

    Fragment-Based Drug Discovery: A Practical Approach

    Mark Brewer, Osamu Ichihara, Christian Kirchhoff, Markus Schade, Mark Whittaker, Pages: 39–62, 2008

    Published Online : 27 OCT 2008, DOI: 10.1002/9780470721551.ch3

  16. A minimalist approach to fragment-based ligand design using common rings and linkers: Application to kinase inhibitors

    Proteins: Structure, Function, and Bioinformatics

    Volume 57, Issue 1, 1 October 2004, Pages: 36–50, Alex M. Aronov and Guy W. Bemis

    Version of Record online : 25 MAY 2004, DOI: 10.1002/prot.20173

  17. You have free access to this content
    Index

    Fragment-based Approaches in Drug Discovery

    Wolfgang Jahnke, Daniel A. Erlanson, Pages: 365–369, 2006

    Published Online : 28 AUG 2006, DOI: 10.1002/3527608761.index

  18. Structure-Based De Novo Drug Design

    De novo Molecular Design

    Alla Srinivas Reddy, Lu Chen, Shuxing Zhang, Pages: 97–124, 2013

    Published Online : 11 OCT 2013, DOI: 10.1002/9783527677016.ch4

  19. Strategies for Fragment Library Design

    Fragment-based Drug Discovery Lessons and Outlook

    Justin Bower, Angelo Pugliese, Martin Drysdale, Pages: 99–118, 2016

    Published Online : 8 JAN 2016, DOI: 10.1002/9783527683604.ch05

  20. ChemInform Abstract: Fragment-Based Drug Discovery: Concept and Aim

    ChemInform

    Volume 41, Issue 29, July 20, 2010, Page: no, Daisuke Tanaka

    Version of Record online : 24 JUN 2010, DOI: 10.1002/chin.201029251