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There are 3431 results for: content related to: Tensions in Licensing and Reimbursement Decisions: The Case of Riluzole for Amytrophic Lateral Sclerosis

  1. You have free access to this content
    A Review of the Neural Mechanisms of Action and Clinical Efficiency of Riluzole in Treating Amyotrophic Lateral Sclerosis: What have we Learned in the Last Decade?

    CNS Neuroscience & Therapeutics

    Volume 17, Issue 1, February 2011, Pages: 4–31, Mark C. Bellingham

    Article first published online : 10 MAR 2010, DOI: 10.1111/j.1755-5949.2009.00116.x

  2. Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)

    Intervention Review

    The Cochrane Library

    Robert G Miller, J D Mitchell and Dan H Moore

    Published Online : 14 MAR 2012, DOI: 10.1002/14651858.CD001447.pub3

  3. Riluzole is a potent drug to protect neonatal rat hypoglossal motoneurons in vitro from excitotoxicity due to glutamate uptake block

    European Journal of Neuroscience

    Volume 33, Issue 5, March 2011, Pages: 899–913, Alessandra Cifra, Francesca Nani and Andrea Nistri

    Article first published online : 17 FEB 2011, DOI: 10.1111/j.1460-9568.2010.07579.x

  4. You have free access to this content
    Riluzole activates TRPC5 channels independently of PLC activity

    British Journal of Pharmacology

    Volume 171, Issue 1, January 2014, Pages: 158–170, Julia M Richter, Michael Schaefer and Kerstin Hill

    Article first published online : 10 DEC 2013, DOI: 10.1111/bph.12436

  5. You have free access to this content
    Protective Effects of Riluzole on Dopamine Neurons

    Journal of Neurochemistry

    Volume 75, Issue 6, December 2000, Pages: 2259–2269, Alexander Storch, Katrin Burkhardt, Albert C. Ludolph and Johannes Schwarz

    Article first published online : 29 JUL 2008, DOI: 10.1046/j.1471-4159.2000.0752259.x

  6. Riluzole promotes cell survival and neurite outgrowth in rat sensory neurones in vitro

    European Journal of Neuroscience

    Volume 24, Issue 12, December 2006, Pages: 3343–3353, Peter J. Shortland, Veronica H. L. Leinster, William White and Lesley G. Robson

    Article first published online : 6 DEC 2006, DOI: 10.1111/j.1460-9568.2006.05218.x

  7. You have free access to this content
    Effects of riluzole on electrically evoked neurotransmitter release

    British Journal of Pharmacology

    Volume 130, Issue 6, July 2000, Pages: 1227–1234, T Jehle, J Bauer, E Blauth, A Hummel, M Darstein, T M Freiman and T J Feuerstein

    Article first published online : 29 JAN 2009, DOI: 10.1038/sj.bjp.0703424

  8. Riluzole is a Promising Pharmacological Inhibitor of Bilirubin-Induced Excitotoxicity in the Ventral Cochlear Nucleus

    CNS Neuroscience & Therapeutics

    Volume 21, Issue 3, March 2015, Pages: 262–270, Guo-Ying Han, Chun-Yan Li, Hai-Bo Shi, Ji-Ping Wang, Kai-Ming Su, Xin-Lu Yin and Shan-Kai Yin

    Article first published online : 12 DEC 2014, DOI: 10.1111/cns.12355

  9. You have free access to this content
    Antioxidative and Proapoptotic Effects of Riluzole on Cultured Cortical Neurons

    Journal of Neurochemistry

    Volume 72, Issue 2, February 1999, Pages: 716–723, Jae-Young Koh, Dae-Kyong Kim, Jee Yeon Hwang, Yang Hee Kim and Ji Heui Seo

    Article first published online : 1 MAY 2002, DOI: 10.1046/j.1471-4159.1999.0720716.x

  10. Pharmacokinetics of riluzole: evidence for glucuronidation as a major metabolic pathway not associated with UGT1A1 genotype

    Biopharmaceutics & Drug Disposition

    Volume 29, Issue 3, January 2008, Pages: 139–144, H. J. M. van Kan, L. H. van den Berg, G. J. Groeneveld, R. J. H. M. van der Straaten, P. W. J. van Vught, L. Lie-A-Huen and H.-J. Guchelaar

    Article first published online : 21 DEC 2007, DOI: 10.1002/bdd.594

  11. Riluzole

    CNS Drug Reviews

    Volume 2, Issue 1, March 1996, Pages: 40–51, Jean Mantz

    Article first published online : 29 SEP 2006, DOI: 10.1111/j.1527-3458.1996.tb00289.x

  12. Riluzole blocks persistent Na+ and Ca2+ currents and modulates release of glutamate via presynaptic NMDA receptors on neonatal rat hypoglossal motoneurons in vitro

    European Journal of Neuroscience

    Volume 27, Issue 10, May 2008, Pages: 2501–2514, Nerijus Lamanauskas and Andrea Nistri

    Article first published online : 28 APR 2008, DOI: 10.1111/j.1460-9568.2008.06211.x

  13. riluzole and motor neuron disease

    Practical Neurology

    Volume 3, Issue 3, June 2003, Pages: 160–169, Martin A. Turner, Ammar Al-Chalabi, Christopher E. Shaw and P. Nigel Leigh

    Article first published online : 28 JUN 2008, DOI: 10.1046/j.1474-7766.2003.07145.x

  14. You have free access to this content
    Riluzole blocks human muscle acetylcholine receptors

    The Journal of Physiology

    Volume 590, Issue 10, May 2012, Pages: 2519–2528, Cristina Deflorio, Eleonora Palma, Luca Conti, Cristina Roseti, Alessia Manteca, Elena Giacomelli, Myriam Catalano, Cristina Limatola, Maurizio Inghilleri and Francesca Grassi

    Article first published online : 15 MAY 2012, DOI: 10.1113/jphysiol.2012.230201

  15. Single- and Multiple-Dose Pharmacokinetics of Riluzole in White Subjects

    The Journal of Clinical Pharmacology

    Volume 37, Issue 9, September 1997, Pages: 820–827, Dr. Aimé Le Liboux, Dr. Patricia Lefebvre, Dr. Yvonne Le Roux, Dr. Philippe Truffinet, Mr. Michel Aubeneau, Dr. Stéphane Kirkesseli and Dr. Guy Montay

    Article first published online : 11 MAR 2013, DOI: 10.1002/j.1552-4604.1997.tb05630.x

  16. You have full text access to this OnlineOpen article
    Inhibiting drug efflux transporters improves efficacy of ALS therapeutics

    Annals of Clinical and Translational Neurology

    Volume 1, Issue 12, December 2014, Pages: 996–1005, Michael R. Jablonski, Shashirekha S. Markandaiah, Dena Jacob, Ni J. Meng, Ke Li, Victoria Gennaro, Angelo C. Lepore, Davide Trotti and Piera Pasinelli

    Article first published online : 21 NOV 2014, DOI: 10.1002/acn3.141

  17. An Association Study of Riluzole Serum Concentration and Survival and Disease Progression in Patients With ALS

    Clinical Pharmacology & Therapeutics

    Volume 83, Issue 5, May 2008, Pages: 718–722, GJ Groeneveld, HJM van Kan, L Lie-A-Huen, H-J Guchelaar and LH van den Berg

    Article first published online : 26 SEP 2007, DOI: 10.1038/sj.clpt.6100382

  18. Riluzole and amyotrophic lateral sclerosis survival: a population-based study in southern Italy

    European Journal of Neurology

    Volume 14, Issue 3, March 2007, Pages: 262–268, S. Zoccolella, E. Beghi, G. Palagano, A. Fraddosio, V. Guerra, V. Samarelli, V. Lepore, I. L. Simone, P. Lamberti, L. Serlenga, G. Logroscino and for the SLAP registry

    Article first published online : 23 FEB 2007, DOI: 10.1111/j.1468-1331.2006.01575.x

  19. You have free access to this content
    Neuroprotective Profile of Riluzole in In Vivo Models of Acute Neurodegenerative Diseases

    CNS Drug Reviews

    Volume 3, Issue 1, March 1997, Pages: 83–101, J. M. Stutzmann, F. Wahl, J. Pratt, V. Mary, M. Reibaud, E. Tecoult and J. Rataud

    Article first published online : 29 SEP 2006, DOI: 10.1111/j.1527-3458.1997.tb00318.x

  20. A Comparison of the Pharmacokinetics and Tolerability of Riluzole after Repeat Dose Administration in Healthy Elderly and Young Volunteers

    The Journal of Clinical Pharmacology

    Volume 39, Issue 5, May 1999, Pages: 480–486, Dr. Aimé Le Liboux, Dr. Jean-Paul Cachia, Dr. Stéphane Kirkesseli, Mr. Jean-Yves Gautier, Ms. Colette Guimart, Dr. Guy Montay, Dr. Pierre A. M. Peeters, Dr. Edwin Groen, Dr. Jan H. G. Jonkman and Dr. Johannes Wemer

    Article first published online : 8 MAR 2013, DOI: 10.1177/009127009903900507