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There are 11399 results for: content related to: Salvage Therapy for Acute Myeloid Leukemia: Current Strategies and Emerging Therapies

  1. Intracellular Signaling Kinase Inhibitors

    Targeting Protein Kinases for Cancer Therapy

    David J. Matthews, Mary E. Gerritsen, Pages: 567–621, 2010

    Published Online : 11 MAR 2010, DOI: 10.1002/9780470555293.ch10

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    Flavopiridol inhibits lipopolysaccharide-induced TNF-α production through inactivation of nuclear factor-κB and mitogen-activated protein kinases in the MyD88-dependent pathway

    Microbiology and Immunology

    Volume 55, Issue 3, March 2011, Pages: 160–167, Abedul Haque, Naoki Koide, Imtiaz Iftakhar-E-Khuda, Abu Shadat Mohammod Noman, Erdenezaya Odkhuu, Battuvshin Badamtseren, Yoshikazu Naiki, Takayuki Komatsu, Tomoaki Yoshida and Takashi Yokochi

    Version of Record online : 23 FEB 2011, DOI: 10.1111/j.1348-0421.2010.00304.x

  3. Investigation of the cytotoxic effect of flavopiridol in canine lymphoma cell lines

    Veterinary and Comparative Oncology

    Y. Ema, M. Igase, Y. Takeda, T. Yanase, S. Umeki, H. Hiraoka, M. Okuda and T. Mizuno

    Version of Record online : 26 JAN 2015, DOI: 10.1111/vco.12130

  4. Flavopiridol as a radio-sensitizer for esophageal cancer cell lines

    Diseases of the Esophagus

    Volume 17, Issue 4, December 2004, Pages: 338–344, S. Sato, Y. Kajiyama, M. Sugano, Y. Iwanuma and M. Tsurumaru

    Version of Record online : 24 NOV 2004, DOI: 10.1111/j.1442-2050.2004.00437.x

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    Reduced occurrence of tumor flare with flavopiridol followed by combined flavopiridol and lenalidomide in patients with relapsed chronic lymphocytic leukemia (CLL)

    American Journal of Hematology

    Volume 90, Issue 4, April 2015, Pages: 327–333, Kami Maddocks, Lai Wei, Darlene Rozewski, Yao Jiang, Yuan Zhao, Mikhil Adusumilli, William E. Pierceall, Camille Doykin, Michael H. Cardone, Jeffrey A. Jones, Joseph Flynn, Leslie A. Andritsos, Michael R. Grever, John C. Byrd, Amy J. Johnson, Mitch A. Phelps and Kristie A Blum

    Version of Record online : 25 FEB 2015, DOI: 10.1002/ajh.23946

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    Cell cycle-independent induction of apoptosis by the anti-tumor drug flavopiridol in endothelial cells

    International Journal of Cancer

    Volume 77, Issue 1, 3 July 1998, Pages: 146–152, Sabine Brüsselbach, Dirk M. Nettelbeck, Hans-Harald Sedlacek and Rolf Müller

    Version of Record online : 6 DEC 1998, DOI: 10.1002/(SICI)1097-0215(19980703)77:1<146::AID-IJC22>3.0.CO;2-B

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    CDKI-71, a novel CDK9 inhibitor, is preferentially cytotoxic to cancer cells compared to flavopiridol

    International Journal of Cancer

    Volume 130, Issue 5, 1 March 2012, Pages: 1216–1226, Xiangrui Liu, Shenhua Shi, Frankie Lam, Chris Pepper, Peter M. Fischer and Shudong Wang

    Version of Record online : 21 JUN 2011, DOI: 10.1002/ijc.26127

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    Identification of cytosolic aldehyde dehydrogenase 1 from non-small cell lung carcinomas as a flavopiridol-binding protein

    FEBS Letters

    Volume 454, Issue 1-2, July 02, 1999, Pages: 100–104, Joachim B. Schnier, Gurmet Kaur, Astrid Kaiser, Sherman F. Stinson, Edward A. Sausville, John Gardner, Kayoko Nishi, E.Morton Bradbury and Adrian M. Senderowicz

    Version of Record online : 6 JUL 1999, DOI: 10.1016/S0014-5793(99)00773-5

  9. Preclinical study of treatment response in HCT-116 cells and xenografts with 1H-decoupled 31P MRS

    NMR in Biomedicine

    Volume 24, Issue 9, November 2011, Pages: 1159–1168, Moses M. Darpolor, Peter T. Kennealey, H. Carl Le, Kristen L. Zakian, Ellen Ackerstaff, Asif Rizwan, Jin-Hong Chen, Elliot B. Sambol, Gary K. Schwartz, Samuel Singer and Jason A. Koutcher

    Version of Record online : 24 MAR 2011, DOI: 10.1002/nbm.1674

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    Delayed combinatorial treatment with flavopiridol and minocycline provides longer term protection for neuronal soma but not dendrites following global ischemia

    Journal of Neurochemistry

    Volume 105, Issue 3, May 2008, Pages: 703–713, Grace O. Iyirhiaro, Tyson B. Brust, Juliet Rashidian, Zohreh Galehdar, Aweis Osman, Maryam Phillips, Ruth S. Slack, Brian A. MacVicar and David S. Park

    Version of Record online : 6 DEC 2007, DOI: 10.1111/j.1471-4159.2007.05166.x

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    Cyclin-dependent kinase inhibitor, flavopiridol, induces apoptosis and inhibits tumor growth in drug-resistant osteosarcoma and Ewing's family tumor cells

    International Journal of Cancer

    Volume 121, Issue 6, 15 September 2007, Pages: 1212–1218, Yan Li, Kazuhiro Tanaka, Xu Li, Takamitsu Okada, Tomoyuki Nakamura, Minoru Takasaki, Shunsaku Yamamoto, Yoshinao Oda, Masazumi Tsuneyoshi and Yukihide Iwamoto

    Version of Record online : 22 MAY 2007, DOI: 10.1002/ijc.22820

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    Characterization of molecular and cellular functions of the cyclin-dependent kinase CDK9 using a novel specific inhibitor

    British Journal of Pharmacology

    Volume 171, Issue 1, January 2014, Pages: 55–68, T K Albert, C Rigault, J Eickhoff, K Baumgart, C Antrecht, B Klebl, G Mittler and M Meisterernst

    Version of Record online : 10 DEC 2013, DOI: 10.1111/bph.12408

  13. Identification of Flavopiridol Analogues that Selectively Inhibit Positive Transcription Elongation Factor (P-TEFb) and Block HIV-1 Replication


    Volume 10, Issue 12, August 17, 2009, Pages: 2072–2080, Akbar Ali, Animesh Ghosh, Robin S. Nathans, Natalia Sharova, Siobhan O'Brien, Hong Cao, Mario Stevenson and Tariq M. Rana

    Version of Record online : 14 JUL 2009, DOI: 10.1002/cbic.200900303

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    The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

    The EMBO Journal

    Volume 27, Issue 13, July 9, 2008, Pages: 1907–1918, Sonja Baumli, Graziano Lolli, Edward D Lowe, Sonia Troiani, Luisa Rusconi, Alex N Bullock, Judit É Debreczeni, Stefan Knapp and Louise N Johnson

    Version of Record online : 19 JUN 2008, DOI: 10.1038/emboj.2008.121

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    Transactivation of cyclin E gene by EWS-Fli1 and antitumor effects of cyclin dependent kinase inhibitor on Ewing's family tumor cells

    International Journal of Cancer

    Volume 116, Issue 3, 1 September 2005, Pages: 385–394, Xu Li, Kazuhiro Tanaka, Fumihiko Nakatani, Tomoya Matsunobu, Riku Sakimura, Masuo Hanada, Takamitsu Okada, Tomoyuki Nakamura and Yukihide Iwamoto

    Version of Record online : 7 APR 2005, DOI: 10.1002/ijc.21010

  16. Efficacy of sequential treatment of HCT116 colon cancer monolayers and xenografts with docetaxel, flavopiridol, and 5-fluorouracil

    Acta Pharmacologica Sinica

    Volume 27, Issue 10, October 2006, Pages: 1375–1381, Jun GUO, An-wu ZHOU, Yu-cai FU, Udit N VERMA, Debu TRIPATHY, Eugene PFRENKEL and Carlos R BECERRA

    Version of Record online : 11 OCT 2006, DOI: 10.1111/j.1745-7254.2006.00421.x

  17. Sequential combinations of flavopiridol and docetaxel inhibit prostate tumors, induce apoptosis, and decrease angiogenesis in the Gγ/T-15 transgenic mouse model of prostate cancer

    The Prostate

    Volume 66, Issue 14, 1 October 2006, Pages: 1487–1497, Teresita Reiner, Alicia de las Pozas and Carlos Perez-Stable

    Version of Record online : 18 AUG 2006, DOI: 10.1002/pros.20478

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    Cyclin-Dependent Kinase 9 Inhibition Protects Cartilage From the Catabolic Effects of Proinflammatory Cytokines

    Arthritis & Rheumatology

    Volume 66, Issue 6, June 2014, Pages: 1537–1546, Jasper H. N. Yik, Zi'ang Hu, Ratna Kumari, Blaine A. Christiansen and Dominik R. Haudenschild

    Version of Record online : 27 MAY 2014, DOI: 10.1002/art.38378

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    Treatment with FLT3 inhibitor in patients with FLT3-mutated acute myeloid leukemia is associated with development of secondary FLT3–tyrosine kinase domain mutations


    Volume 120, Issue 14, 15 July 2014, Pages: 2142–2149, Yesid Alvarado, Hagop M. Kantarjian, Rajyalakshmi Luthra, Farhad Ravandi, Gautam Borthakur, Guillermo Garcia-Manero, Marina Konopleva, Zeev Estrov, Michael Andreeff and Jorge E. Cortes

    Version of Record online : 15 APR 2014, DOI: 10.1002/cncr.28705

  20. Diversity of the juxtamembrane and TKD1 mutations (Exons 13–15) in the FLT3 gene with regards to mutant load, sequence, length, localization, and correlation with biological data

    Genes, Chromosomes and Cancer

    Volume 51, Issue 10, October 2012, Pages: 910–924, Susanne Schnittger, Ulrike Bacher, Claudia Haferlach, Tamara Alpermann, Wolfgang Kern and Torsten Haferlach

    Version of Record online : 4 JUN 2012, DOI: 10.1002/gcc.21975