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There are 4663 results for: content related to: The Role of the Apoptosome in Apoptosis and Cancer Therapy

  1. You have free access to this content
    Rsk-mediated phosphorylation and 14-3-3ε binding of Apaf-1 suppresses cytochrome c-induced apoptosis

    The EMBO Journal

    Volume 31, Issue 5, March 7, 2012, Pages: 1279–1292, Jiyeon Kim, Amanda B Parrish, Manabu Kurokawa, Kenkyo Matsuura, Christopher D Freel, Joshua L Andersen, Carrie E Johnson and Sally Kornbluth

    Version of Record online : 13 JAN 2012, DOI: 10.1038/emboj.2011.491

  2. You have free access to this content
    α-Fetoprotein positively regulates cytochrome c-mediated caspase activation and apoptosome complex formation

    European Journal of Biochemistry

    Volume 270, Issue 21, November 2003, Pages: 4388–4399, Lidia Semenkova, 1, Elena Dudich, 1, Igor Dudich, 1 Natalie Tokhtamisheva, 1 Edward Tatulov, 2 Yury Okruzhnov, 3 Jesus Garcia-Foncillas, 3 Juan-Antonio Palop-Cubillo and 4 Timo Korpela 5

    Version of Record online : 16 OCT 2003, DOI: 10.1046/j.1432-1033.2003.03836.x

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    Transforming growth factor-β induces apoptosis in rat FaO hepatoma cells via cytochrome c Release and oligomerization of Apaf-1 to form a ∼700-kd apoptosome caspase–processing complex


    Volume 32, Issue 4, October 2000, Pages: 750–760, Caroline Freathy, David G. Brown, Ruth A. Roberts and Kelvin Cain

    Version of Record online : 30 DEC 2003, DOI: 10.1053/jhep.2000.18329

  4. You have free access to this content
    Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes

    The EMBO Journal

    Volume 20, Issue 5, March 1, 2001, Pages: 998–1009, Shawn B. Bratton, Gail Walker, Srinivasa M. Srinivasula, Xiao-Ming Sun, Michael Butterworth, Emad S. Alnemri and Gerald M. Cohen

    Version of Record online : 1 MAR 2001, DOI: 10.1093/emboj/20.5.998

  5. Cytochrome c and insect cell apoptosis

    Insect Science

    Volume 19, Issue 1, February 2012, Pages: 30–40, Kai-Yu Liu, Hong Yang, Jian-Xin Peng and Hua-Zhu Hong

    Version of Record online : 9 SEP 2011, DOI: 10.1111/j.1744-7917.2011.01431.x

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    The Apaf-1•procaspase-9 apoptosome complex functions as a proteolytic-based molecular timer

    The EMBO Journal

    Volume 28, Issue 13, July 8, 2009, Pages: 1916–1925, Srinivas Malladi, Madhavi Challa-Malladi, Howard O Fearnhead and Shawn B Bratton

    Version of Record online : 4 JUN 2009, DOI: 10.1038/emboj.2009.152

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    Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes

    The EMBO Journal

    Volume 23, Issue 10, May 19, 2004, Pages: 2134–2145, Michelle M Hill, Colin Adrain, Patrick J Duriez, Emma M Creagh and Seamus J Martin

    Version of Record online : 22 APR 2004, DOI: 10.1038/sj.emboj.7600210

  8. You have full text access to this Open Access content
    The mitochondrial death pathway: a promising therapeutic target in diseases

    Journal of Cellular and Molecular Medicine

    Volume 13, Issue 6, June 2009, Pages: 1004–1033, Sanjeev Gupta, George E.N. Kass, Eva Szegezdi and Bertrand Joseph

    Version of Record online : 11 FEB 2009, DOI: 10.1111/j.1582-4934.2009.00697.x

  9. Molecules that modulate Apaf-1 activity

    Medicinal Research Reviews

    Volume 31, Issue 4, July 2011, Pages: 649–675, Enrique Pérez-Payá, Mar Orzáez, Laura Mondragón, Dennis Wolan, James A. Wells, Angel Messeguer and María J. Vicent

    Version of Record online : 22 JAN 2010, DOI: 10.1002/med.20198

  10. You have full text access to this Open Access content
    Physiological and pathological roles of Apaf1 and the apoptosome

    Journal of Cellular and Molecular Medicine

    Volume 7, Issue 1, January 2003, Pages: 21–34, E. Ferraro, M. Corvaro and F. Cecconi

    Version of Record online : 1 MAY 2007, DOI: 10.1111/j.1582-4934.2003.tb00199.x

  11. The Apoptosome: The Executioner of Mitochondria-mediated Apoptosis

    Standard Article


    Elisabetta Ferraro and Francesco Cecconi

    Published Online : 15 SEP 2009, DOI: 10.1002/9780470015902.a0021573

  12. You have free access to this content
    Huntingtin-interacting protein 1-mediated neuronal cell death occurs through intrinsic apoptotic pathways and mitochondrial alterations

    FEBS Letters

    Volume 580, Issue 22, October 02, 2006, Pages: 5275–5282, Shin Ae Choi, Steven J. Kim and Kwang Chul Chung

    Version of Record online : 11 SEP 2006, DOI: 10.1016/j.febslet.2006.08.076

  13. Apoptosome and Caspase Activation

    Standard Article

    Wiley Encyclopedia of Chemical Biology

    Wim Declercq and Peter Vandenabeele

    Published Online : 15 MAY 2008, DOI: 10.1002/9780470048672.wecb019

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    Immunology in clinic review series; focus on autoinflammatory diseases: inflammasomes: mechanisms of activation

    Clinical & Experimental Immunology

    Volume 167, Issue 3, March 2012, Pages: 369–381, A. K. Mankan, A. Kubarenko and V. Hornung

    Version of Record online : 30 JAN 2012, DOI: 10.1111/j.1365-2249.2011.04534.x

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    Proapoptotic histone H1.2 induces CASP-3 and -7 activation by forming a protein complex with CYT c, APAF-1 and CASP-9

    FEBS Letters

    Volume 581, Issue 18, July 24, 2007, Pages: 3422–3428, Antonio Ruiz-Vela and Stanley J. Korsmeyer

    Version of Record online : 28 JUN 2007, DOI: 10.1016/j.febslet.2007.06.049

  16. You have free access to this content
    Specific nitration of tyrosines 46 and 48 makes cytochrome c assemble a non-functional apoptosome

    FEBS Letters

    Volume 586, Issue 2, January 20, 2012, Pages: 154–158, José M. García-Heredia, Irene Díaz-Moreno, Antonio Díaz-Quintana, Mar Orzáez, José A. Navarro, Manuel Hervás and Miguel A. De la Rosa

    Version of Record online : 16 DEC 2011, DOI: 10.1016/j.febslet.2011.12.007

  17. You have free access to this content
    Role of Bcl-2 family proteins in apoptosis: apoptosomes or mitochondria?

    Genes to Cells

    Volume 3, Issue 11, November 1998, Pages: 697–707, Yoshihide Tsujimoto

    Version of Record online : 25 DEC 2001, DOI: 10.1046/j.1365-2443.1998.00223.x

  18. You have free access to this content
    Over-expression of HSP70 attenuates caspase-dependent and caspase-independent pathways and inhibits neuronal apoptosis

    Journal of Neurochemistry

    Volume 123, Issue 4, November 2012, Pages: 542–554, Boris Sabirzhanov, Bogdan A. Stoica, Marie Hanscom, Chun-Shu Piao and Alan I. Faden

    Version of Record online : 28 SEP 2012, DOI: 10.1111/j.1471-4159.2012.07927.x

  19. The Use of Proteomics to Identify and Characterize Cell Death Proteins

    When Cells Die II: A Comprehensive Evaluation of Apoptosis and Programmed Cell Death

    Xavier Saelens, Geert van Loo, Kris Gevaert, Joel Vandekerckhove, Peter Vandenabeele, Pages: 403–434, 2005

    Published Online : 28 JAN 2005, DOI: 10.1002/0471476501.ch16

  20. Role of Mitochondrial Proteins in Apoptosis

    Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts

    Xavier Saelens, Nele Festjens, Lieselotte Vande Walle, Peter Vandenabeele, Pages: 185–221, 2008

    Published Online : 26 MAY 2008, DOI: 10.1002/9783527619665.ch6