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There are 34766 results for: content related to: The Role of the Bcl-2 Protein Family in Tumorigenesis and Cancer Therapy

  1. You have free access to this content
    BH3-only proteins: The death-puppeteer's wires

    Cytometry Part A

    Volume 77A, Issue 1, January 2010, Pages: 11–21, Fabio Ghiotto, Franco Fais and Silvia Bruno

    Version of Record online : 6 NOV 2009, DOI: 10.1002/cyto.a.20819

  2. You have free access to this content
    BH3-only proteins: a 20-year stock-take

    The FEBS Journal

    Volume 282, Issue 6, March 2015, Pages: 1006–1016, Marcel Doerflinger, Jason A. Glab and Hamsa Puthalakath

    Version of Record online : 26 JAN 2015, DOI: 10.1111/febs.13190

  3. Bax, Bak and Bid: Key Mediators of Apoptosis

    Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts

    Clare E. Dempsey, Darren L. Roberts, Caroline Dive, Pages: 346–378, 2008

    Published Online : 26 MAY 2008, DOI: 10.1002/9783527619665.ch12

  4. You have free access to this content
    Cell death and the mitochondria: therapeutic targeting of the BCL-2 family-driven pathway

    British Journal of Pharmacology

    Volume 171, Issue 8, April 2014, Pages: 1973–1987, M J Roy, A Vom, P E Czabotar and G Lessene

    Version of Record online : 28 MAR 2014, DOI: 10.1111/bph.12431

  5. The BH3-only Proteins Puma and Noxa: Two Brothers in Arms

    Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts

    Miriam Erlacher, Ewa M. Michalak, Andreas Strasser, Andreas Villunger, Pages: 379–402, 2008

    Published Online : 26 MAY 2008, DOI: 10.1002/9783527619665.ch13

  6. Bh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysis

    Proteins: Structure, Function, and Bioinformatics

    Volume 83, Issue 7, July 2015, Pages: 1262–1272, Sreekanth Rajan, Minjoo Choi, Kwanghee Baek and Ho Sup Yoon

    Version of Record online : 23 MAY 2015, DOI: 10.1002/prot.24816

  7. You have free access to this content
    The structure of Boo/Diva reveals a divergent Bcl-2 protein

    Proteins: Structure, Function, and Bioinformatics

    Volume 78, Issue 9, July 2010, Pages: 2181–2186, Gilles J. P. Rautureau, Catherine L. Day and Mark G. Hinds

    Version of Record online : 23 MAR 2010, DOI: 10.1002/prot.22728

  8. You have full text access to this OnlineOpen article
    Haematopoietic stem cell survival and transplantation efficacy is limited by the BH3-only proteins Bim and Bmf

    EMBO Molecular Medicine

    Volume 5, Issue 1, January 2013, Pages: 122–136, Verena Labi, Daniela Bertele, Claudia Woess, Denise Tischner, Florian J. Bock, Sven Schwemmers, Heike L. Pahl, Stephan Geley, Mirjam Kunze, Charlotte M. Niemeyer, Andreas Villunger and Miriam Erlacher

    Version of Record online : 24 NOV 2012, DOI: 10.1002/emmm.201201235

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    Completing the family portrait of the anti-apoptotic Bcl-2 proteins: Crystal structure of human Bfl-1 in complex with Bim

    FEBS Letters

    Volume 582, Issue 25-26, October 29, 2008, Pages: 3590–3594, Maria Dolores Herman, Tomas Nyman, Martin Welin, Lari Lehtiö, Susanne Flodin, Lionel Trésaugues, Tetyana Kotenyova, Alex Flores and Pär Nordlund

    Version of Record online : 21 SEP 2008, DOI: 10.1016/j.febslet.2008.09.028

  10. You have free access to this content
    Role of Bcl-2 in tumour cell survival and implications for pharmacotherapy

    Journal of Pharmacy and Pharmacology

    Volume 64, Issue 12, December 2012, Pages: 1695–1702, Mary Tomek, Toru Akiyama and Crispin R. Dass

    Version of Record online : 25 APR 2012, DOI: 10.1111/j.2042-7158.2012.01526.x

  11. You have free access to this content
    BH3-only protein bid participates in the Bcl-2 network in healthy liver cells

    Hepatology

    Volume 50, Issue 6, December 2009, Pages: 1972–1980, Hayato Hikita, Tetsuo Takehara, Takahiro Kodama, Satoshi Shimizu, Atsushi Hosui, Takuya Miyagi, Tomohide Tatsumi, Hisashi Ishida, Kazuyoshi Ohkawa, Wei Li, Tatsuya Kanto, Naoki Hiramatsu, Lothar Hennighausen, Xiao-Ming Yin and Norio Hayashi

    Version of Record online : 5 AUG 2009, DOI: 10.1002/hep.23207

  12. You have free access to this content
    BH3-only protein Bim inhibits activity of antiapoptotic members of Bcl-2 family when expressed in yeast

    FEBS Letters

    Volume 585, Issue 17, September 02, 2011, Pages: 2709–2713, Barbora Juhásová, Marek Mentel, Ingrid Bhatia-Kiššová, Igor Zeman, Jordan Kolarov, Michael Forte and Peter Polčic

    Version of Record online : 31 JUL 2011, DOI: 10.1016/j.febslet.2011.07.027

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    Direct addition of BimL to mitochondria does not lead to cytochrome c release

    FEBS Letters

    Volume 522, Issue 1-3, July 03, 2002, Pages: 29–34, Olivier Terradillos, Sylvie Montessuit, David C.S Huang and Jean-Claude Martinou

    Version of Record online : 3 JUN 2002, DOI: 10.1016/S0014-5793(02)02871-5

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    The liver's dance with death: Two Bcl-2 guardian proteins from the abyss

    Hepatology

    Volume 50, Issue 4, October 2009, Pages: 1009–1013, Sophie C. Cazanave and Gregory J. Gores

    Version of Record online : 20 JUL 2009, DOI: 10.1002/hep.23188

  15. You have full text access to this Open Access content
    The mitochondrial death pathway: a promising therapeutic target in diseases

    Journal of Cellular and Molecular Medicine

    Volume 13, Issue 6, June 2009, Pages: 1004–1033, Sanjeev Gupta, George E.N. Kass, Eva Szegezdi and Bertrand Joseph

    Version of Record online : 11 FEB 2009, DOI: 10.1111/j.1582-4934.2009.00697.x

  16. Survival Factors

    When Cells Die II: A Comprehensive Evaluation of Apoptosis and Programmed Cell Death

    Richard A. Lockshin, Zahra Zakeri, Pages: 255–273, 2005

    Published Online : 28 JAN 2005, DOI: 10.1002/0471476501.ch11

  17. Discovery of a Small-Molecule pBcl-2 Inhibitor that Overcomes pBcl-2-Mediated Resistance to Apoptosis

    ChemBioChem

    Volume 16, Issue 5, March 23, 2015, Pages: 757–765, Dr. Ting Song, Xiaoyan Yu, Dr. Yubo Liu, Dr. Xiangqian Li, Gaobo Chai and Dr. Zhichao Zhang

    Version of Record online : 25 FEB 2015, DOI: 10.1002/cbic.201402639

  18. You have free access to this content
    BH3-in-groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes

    The EMBO Journal

    Volume 35, Issue 2, 18 January 2016, Pages: 208–236, Zhi Zhang, Sabareesh Subramaniam, Justin Kale, Chenyi Liao, Bo Huang, Hetal Brahmbhatt, Samson GF Condon, Suzanne M Lapolla, Franklin A Hays, Jingzhen Ding, Feng He, Xuejun C Zhang, Jianing Li, Alessandro Senes, David W Andrews and Jialing Lin

    Version of Record online : 23 DEC 2015, DOI: 10.15252/embj.201591552

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    That which does not kill me makes me stronger; combining ERK1/2 pathway inhibitors and BH3 mimetics to kill tumour cells and prevent acquired resistance

    British Journal of Pharmacology

    Volume 169, Issue 8, August 2013, Pages: 1708–1722, Matthew J Sale and Simon J Cook

    Version of Record online : 26 JUL 2013, DOI: 10.1111/bph.12220

  20. You have free access to this content
    Noxa is necessary for hydrogen peroxide-induced caspase-dependent cell death

    FEBS Letters

    Volume 584, Issue 4, February 19, 2010, Pages: 681–688, Tomonori Aikawa, Koei Shinzawa, Nobuyuki Tanaka and Yoshihide Tsujimoto

    Version of Record online : 19 JAN 2010, DOI: 10.1016/j.febslet.2010.01.026