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There are 22034 results for: content related to: Inhibition of the Molecular Chaperone Heat Shock Protein 90 in Cancer: Consequences for the Regulation of Survival Signaling and Induction of Cell Death

  1. Hsp90 inhibitors: Small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation

    Medicinal Research Reviews

    Volume 26, Issue 3, May 2006, Pages: 310–338, Brian S. J. Blagg and Timothy D. Kerr

    Article first published online : 29 DEC 2005, DOI: 10.1002/med.20052

  2. PLCγ1–PKCγ Signaling-Mediated Hsp90α Plasma Membrane Translocation Facilitates Tumor Metastasis

    Traffic

    Volume 15, Issue 8, August 2014, Pages: 861–878, Jian Yang, Xiaomin Song, Yang Chen, Xin-an Lu, Yan Fu and Yongzhang Luo

    Article first published online : 26 JUN 2014, DOI: 10.1111/tra.12179

  3. Computational Studies of Allosteric Regulation in the Hsp90 Molecular Chaperone: From Functional Dynamics and Protein Structure Networks to Allosteric Communications and Targeted Anti-Cancer Modulators

    Israel Journal of Chemistry

    Volume 54, Issue 8-9, August 2014, Pages: 1052–1064, Gennady M. Verkhivker

    Article first published online : 19 FEB 2014, DOI: 10.1002/ijch.201300143

  4. You have free access to this content
    Human heat shock protein (Hsp) 90 interferes with Neisseria meningitidis adhesin A (NadA)-mediated adhesion and invasion

    Cellular Microbiology

    Volume 14, Issue 3, March 2012, Pages: 368–385, Paolo Montanari, Giuseppe Bozza, Barbara Capecchi, Elena Caproni, Riccardo Barrile, Nathalie Norais, Mirco Capitani, Michele Sallese, Paola Cecchini, Laura Ciucchi, Zhenai Gao, Rino Rappuoli, Mariagrazia Pizza, Beatrice Aricò and Marcello Merola

    Article first published online : 8 DEC 2011, DOI: 10.1111/j.1462-5822.2011.01722.x

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    Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery

    The EMBO Journal

    Volume 23, Issue 3, February 11, 2004, Pages: 511–519, Philippe Meyer, Chrisostomos Prodromou, Chunyan Liao, Bin Hu, S Mark Roe, Cara K Vaughan, Ignacija Vlasic, Barry Panaretou, Peter W Piper and Laurence H Pearl

    Article first published online : 22 JAN 2004, DOI: 10.1038/sj.emboj.7600060

    Corrected by:

    Erratum: Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery

    Vol. 23, Issue 6, 1402–1410, Article first published online: 24 MAR 2004

  6. Heat shock protein 90 maintains the stability and function of transcription factor Broad Z7 by interacting with its Broad-Complex-Tramtrack-Bric-a-brac domain

    Insect Molecular Biology

    Volume 23, Issue 6, December 2014, Pages: 720–732, M.-J. Cai, X.-R. Li, X.-Y. Pei, W. Liu, J.-X. Wang and X.-F. Zhao

    Article first published online : 24 JUL 2014, DOI: 10.1111/imb.12118

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    Apo-Hsp90 coexists in two open conformational states in solution

    Biology of the Cell

    Volume 100, Issue 7, July 2008, Pages: 413–425, Patrick Bron, Emmanuel Giudice, Jean-Paul Rolland, Rubén M. Buey, Pascale Barbier, J. Fernando Díaz, Vincent Peyrot, Daniel Thomas and Cyrille Garnier

    Article first published online : 9 JAN 2012, DOI: 10.1042/BC20070149

  8. Under cover: causes, effects and implications of Hsp90-mediated genetic capacitance

    BioEssays

    Volume 26, Issue 4, April 2004, Pages: 348–362, Todd A. Sangster, Susan Lindquist and Christine Queitsch

    Article first published online : 26 MAR 2004, DOI: 10.1002/bies.20020

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    Regulation of Embryonic Stem Cell Pluripotency by Heat Shock Protein 90

    STEM CELLS

    Volume 30, Issue 8, August 2012, Pages: 1624–1633, Eric Bradley, Erhard Bieberich, Nahid F. Mivechi, Dantera Tangpisuthipongsa and Guanghu Wang

    Article first published online : 24 JUL 2012, DOI: 10.1002/stem.1143

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    Oxidative inhibition of Hsp90 disrupts the super-chaperone complex and attenuates pancreatic adenocarcinoma in vitro and in vivo

    International Journal of Cancer

    Volume 132, Issue 3, 1 February 2013, Pages: 695–706, Sayantani Sarkar, Devawati Dutta, Suman Kumar Samanta, Kaushik Bhattacharya, Bikas Chandra Pal, Jinping Li, Kaustubh Datta, Chhabinath Mandal and Chitra Mandal

    Article first published online : 9 JUL 2012, DOI: 10.1002/ijc.27687

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    Novel therapeutic strategies in multiple myeloma: role of the heat shock protein inhibitors

    European Journal of Haematology

    Volume 86, Issue 2, February 2011, Pages: 93–110, Alessandro Allegra, Emanuela Sant’Antonio, Giuseppa Penna, Andrea Alonci, Arianna D’Angelo, Sabina Russo, Antonino Cannavò, Demetrio Gerace and Caterina Musolino

    Article first published online : 20 DEC 2010, DOI: 10.1111/j.1600-0609.2010.01558.x

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    Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery

    The EMBO Journal

    Volume 23, Issue 6, March 24, 2004, Pages: 1402–1410, Philippe Meyer et al

    Article first published online : 24 MAR 2004, DOI: 10.1038/sj.emboj.7600141

    This article corrects:

    Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery

    Vol. 23, Issue 3, 511–519, Article first published online: 22 JAN 2004

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    Identification of Citrullinated Hsp90 Isoforms as Novel Autoantigens in Rheumatoid Arthritis–Associated Interstitial Lung Disease

    Arthritis & Rheumatism

    Volume 65, Issue 4, April 2013, Pages: 869–879, Lisa Harlow, Ivan O. Rosas, Bernadette R. Gochuico, Ted R. Mikuls, Paul F. Dellaripa, Chester V. Oddis and Dana P. Ascherman

    Article first published online : 28 MAR 2013, DOI: 10.1002/art.37881

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    The Role of the 90-kDa Heat-Shock Protein and its Associated Cohorts in Stabilizing the Heme-Regulated Eif-24Al Kinase in Reticulocyte Lysates during Heat Stress

    European Journal of Biochemistry

    Volume 246, Issue 2, June 1997, Pages: 461–470, Zuoyu Xu, Jayanta K. Pal, Vanitha Thulasiraman, Hejin P. Hahn, Jane-Jane Chen and Robert L. Matts

    Article first published online : 16 JUL 2004, DOI: 10.1111/j.1432-1033.1997.t01-1-00461.x

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    Heat shock protein 90 and its co-chaperone protein phosphatase 5 interact with distinct regions of the tomato I-2 disease resistance protein

    The Plant Journal

    Volume 43, Issue 2, July 2005, Pages: 284–298, Sergio De La Fuente Bentem van, Jack H. Vossen, Klaas Jan de Vries, Saskia van Wees, Wladimir I.L. Tameling, Henk L. Dekker, Chris G. de Koster, Michel A. Haring, Frank L.W. Takken and Ben J.C. Cornelissen

    Article first published online : 17 JUN 2005, DOI: 10.1111/j.1365-313X.2005.02450.x

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    Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast

    European Journal of Biochemistry

    Volume 270, Issue 23, December 2003, Pages: 4689–4695, Peter W. Piper, Stefan H. Millson, Mehdi Mollapour, Barry Panaretou, Giuliano Siligardi, Laurence H. Pearl and Chrisostomos Prodromou

    Article first published online : 28 NOV 2003, DOI: 10.1046/j.1432-1033.2003.03866.x

  17. Artificial Accelerators of the Molecular Chaperone Hsp90 Facilitate Rate-Limiting Conformational Transitions

    Angewandte Chemie International Edition

    Volume 53, Issue 45, November 3, 2014, Pages: 12257–12262, Bettina K. Zierer, Matthias Weiwad, Martin Rübbelke, Lee Freiburger, Gunter Fischer, Oliver R. Lorenz, Michael Sattler, Klaus Richter and Johannes Buchner

    Article first published online : 22 SEP 2014, DOI: 10.1002/anie.201406578

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    Structural and functional analysis of SGT1–HSP90 core complex required for innate immunity in plants

    EMBO reports

    Volume 9, Issue 12, December 2008, Pages: 1209–1215, Yasuhiro Kadota, Beatrice Amigues, Lionel Ducassou, Hocine Madaoui, Francoise Ochsenbein, Raphaël Guerois and Ken Shirasu

    Article first published online : 3 OCT 2008, DOI: 10.1038/embor.2008.185

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    A hydrophobic segment within the C-terminal domain is essential for both client-binding and dimer formation of the HSP90-family molecular chaperone

    European Journal of Biochemistry

    Volume 270, Issue 1, January 2003, Pages: 146–154, Shin-ichi Yamada, Toshio Ono, Akio Mizuno and Takayuki K Nemoto

    Article first published online : 13 DEC 2002, DOI: 10.1046/j.1432-1033.2003.03375.x

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    Hsp90-dependent regulatory circuitry controlling temperature-dependent fungal development and virulence

    Cellular Microbiology

    Volume 16, Issue 4, April 2014, Pages: 473–481, Teresa R. O'Meara and Leah E. Cowen

    Article first published online : 14 FEB 2014, DOI: 10.1111/cmi.12266