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There are 1966 results for: content related to: Synthesis of Sitagliptin, the Active Ingredient in Januvia® and Janumet®

  1. Effect of a Single Cyclosporine Dose on the Single-Dose Pharmacokinetics of Sitagliptin (MK-0431), a Dipeptidyl Peptidase-4 Inhibitor, in Healthy Male Subjects

    The Journal of Clinical Pharmacology

    Volume 47, Issue 2, February 2007, Pages: 165–174, Dr Rajesh Krishna, Dr Arthur Bergman, Dr Patrick Larson, Mr Josee Cote, Dr Kenneth Lasseter, Ms Stacey Dilzer, Dr Amy Wang, Dr Wei Zeng, Mr Li Chen, Dr John Wagner and Dr Gary Herman

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270006296523

  2. Sitagliptin and pioglitazone provide complementary effects on postprandial glucose and pancreatic islet cell function

    Diabetes, Obesity and Metabolism

    Volume 15, Issue 12, December 2013, Pages: 1101–1110, M. Alba, B. Ahrén, S. E. Inzucchi, Y. Guan, M. Mallick, L. Xu, E. A. O'Neill, D. E. Williams-Herman, K. D. Kaufman and B. J. Goldstein

    Article first published online : 18 JUL 2013, DOI: 10.1111/dom.12145

  3. You have free access to this content
    Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, compared with the sulfonylurea, glipizide, in patients with type 2 diabetes inadequately controlled on metformin alone: a randomized, double-blind, non-inferiority trial

    Diabetes, Obesity and Metabolism

    Volume 9, Issue 2, March 2007, Pages: 194–205, M. A. Nauck, G. Meininger, D. Sheng, L. Terranella, P. P. Stein and Sitagliptin Study 024 Group

    Article first published online : 26 JAN 2007, DOI: 10.1111/j.1463-1326.2006.00704.x

  4. Dipeptidyl Peptidase-4 Inhibitors for the Treatment of Type 2 Diabetes Mellitus

    Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

    Volume 30, Issue 5, May 2010, Pages: 463–484, Dr. Joshua J. Neumiller, Dr. Lindy Wood and Mr. R. Keith Campbell

    Article first published online : 6 JAN 2012, DOI: 10.1592/phco.30.5.463

  5. Efficacy and safety of sitagliptin when added to ongoing metformin therapy in patients with type 2 diabetes

    Diabetes, Obesity and Metabolism

    Volume 10, Issue 10, October 2008, Pages: 959–969, R. Scott, T. Loeys, M. J. Davies, S. S. Engel and for the Sitagliptin Study 801 Group

    Article first published online : 14 JAN 2008, DOI: 10.1111/j.1463-1326.2007.00839.x

  6. Multiple Doses of Sitagliptin, a Selective DPP-4 Inhibitor, Do Not Meaningfully Alter Pharmacokinetics and Pharmacodynamics of Warfarin

    The Journal of Clinical Pharmacology

    Volume 49, Issue 10, October 2009, Pages: 1157–1167, D. Hamish Wright, Gary A. Herman, Andrea Maes, Qi Liu, Amy O. Johnson-Levonas and John A. Wagner

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270009341653

  7. Safety and efficacy of sitagliptin in patients with type 2 diabetes and chronic renal insufficiency

    Diabetes, Obesity and Metabolism

    Volume 10, Issue 7, July 2008, Pages: 545–555, J. C. N. Chan, R. Scott, J. C. Arjona Ferreira, D. Sheng, E. Gonzalez, M. J. Davies, P. P. Stein, K. D. Kaufman, J. M. Amatruda and D. Williams-Herman

    Article first published online : 28 JUN 2008, DOI: 10.1111/j.1463-1326.2008.00914.x

  8. Pharmacokinetics of dipeptidylpeptidase-4 inhibitors

    Diabetes, Obesity and Metabolism

    Volume 12, Issue 8, August 2010, Pages: 648–658, A. J. Scheen

    Article first published online : 27 FEB 2010, DOI: 10.1111/j.1463-1326.2010.01212.x

  9. The effect of initial therapy with the fixed-dose combination of sitagliptin and metformin compared with metformin monotherapy in patients with type 2 diabetes mellitus

    Diabetes, Obesity and Metabolism

    Volume 13, Issue 7, July 2011, Pages: 644–652, C. Reasner, L. Olansky, T. L. Seck, D. E. Williams-Herman, M. Chen, L. Terranella, A. O. Johnson-Levonas, K. D. Kaufman and B. J. Goldstein

    Article first published online : 24 MAY 2011, DOI: 10.1111/j.1463-1326.2011.01390.x

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    Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, in patients with type 2 diabetes mellitus inadequately controlled on glimepiride alone or on glimepiride and metformin

    Diabetes, Obesity and Metabolism

    Volume 9, Issue 5, September 2007, Pages: 733–745, K. Hermansen, M. Kipnes, E. Luo, D. Fanurik, H. Khatami, P. Stein and Sitagliptin Study 035 Group

    Article first published online : 26 JUN 2007, DOI: 10.1111/j.1463-1326.2007.00744.x

  11. Absolute bioavailability of sitagliptin, an oral dipeptidyl peptidase-4 inhibitor, in healthy volunteers

    Biopharmaceutics & Drug Disposition

    Volume 28, Issue 6, September 2007, Pages: 315–322, Arthur Bergman, David Ebel, Fang Liu, Julie Stone, Amy Wang, Wei Zeng, Li Chen, Stacy Dilzer, Kenneth Lasseter, Gary Herman, John Wagner and Rajesh Krishna

    Article first published online : 18 JUN 2007, DOI: 10.1002/bdd.560

  12. You have full text access to this OnlineOpen article
    Sitagliptin: review of preclinical and clinical data regarding incidence of pancreatitis

    International Journal of Clinical Practice

    Volume 64, Issue 7, June 2010, Pages: 984–990, S. S. Engel, D. E. Williams-Herman, G. T. Golm, R. J. Clay, S. V. Machotka, K. D. Kaufman and B. J. Goldstein

    Article first published online : 14 APR 2010, DOI: 10.1111/j.1742-1241.2010.02382.x

  13. You have full text access to this Open Access content
    Sitagliptin added to treatment with ongoing pioglitazone for up to 52 weeks improves glycemic control in Japanese patients with type 2 diabetes

    Journal of Diabetes Investigation

    Volume 2, Issue 5, October 2011, Pages: 381–390, Atsunori Kashiwagi, Takashi Kadowaki, Naoko Tajima, Kenji Nonaka, Tadaaki Taniguchi, Mikio Nishii, Juan Camilo Arjona Ferreira and John M Amatruda

    Article first published online : 8 APR 2011, DOI: 10.1111/j.2040-1124.2011.00120.x

  14. You have full text access to this Open Access content
    Efficacy and safety of sitagliptin monotherapy and combination therapy in Japanese type 2 diabetes patients

    Journal of Diabetes Investigation

    Volume 3, Issue 6, December 2012, Pages: 503–509, Akira Kubota, Hajime Maeda, Akira Kanamori, Kiyokazu Matoba, Yasuyuki Jin, Fuyuki Minagawa, Mitsuo Obana, Kotaro Iemitsu, Shogo Ito, Hikaru Amamiya, Mizuki Kaneshiro, Masahiko Takai, Hideaki Kaneshige, Kazuhiko Hoshino, Masashi Ishikawa, Nobuaki Minami, Tetsuro Takuma, Nobuo Sasai, Sachio Aoyagi, Takehiro Kawata, Atsuko Mokubo, Hiroshi Takeda, Shin Honda, Hideo Machimura, Tetsuya Motomiya, Manabu Waseda, Yoshikazu Naka, Yasushi Tanaka, Yasuo Terauchi and Ikuro Matsuba

    Article first published online : 26 JUN 2012, DOI: 10.1111/j.2040-1124.2012.00221.x

  15. You have full text access to this Open Access content
    Sitagliptin added to voglibose monotherapy improves glycemic control in patients with type 2 diabetes

    Journal of Diabetes Investigation

    Volume 4, Issue 6, November 2013, Pages: 595–604, Naoko Tajima, Takashi Kadowaki, Taro Okamoto, Asako Sato, Kotoba Okuyama, Toshiomi Minamide and Juan Camilo Arjona Ferreira

    Article first published online : 21 JUL 2013, DOI: 10.1111/jdi.12116

  16. You have full text access to this OnlineOpen article
    Predictive factors of durability to sitagliptin: Slower reduction of glycated hemoglobin, older age and higher baseline glycated hemoglobin

    Journal of Diabetes Investigation

    Volume 5, Issue 1, January 2014, Pages: 51–59, Hye Soo Chung, Sunghwan Suh, Mi Yeon Kim, Soo Kyoung Kim, Hee Kyung Kim, Ji In Lee, Kyu Yeon Hur, Jae Hyeon Kim, Yong-ki Min, Myung-shik Lee, Kwang-Won Kim, Sun Wook Kim, Jae Hoon Chung and Moon-Kyu Lee

    Article first published online : 2 SEP 2013, DOI: 10.1111/jdi.12127

  17. Pharmacokinetics and Pharmacodynamic Effects of the Oral DPP-4 Inhibitor Sitagliptin in Middle-Aged Obese Subjects

    The Journal of Clinical Pharmacology

    Volume 46, Issue 8, August 2006, Pages: 876–886, Dr Gary A. Herman, Dr Arthur Bergman, Dr Fang Liu, Ms Cathy Stevens, Dr Amy Q. Wang, Mr Wei Zeng, Dr Li Chen, Ms Karen Snyder, Ms Deborah Hilliard, Mr Michael Tanen, Dr Wesley Tanaka, Dr Alan G. Meehan, Dr Kenneth Lasseter, Ms Stacy Dilzer, Dr Robert Blum and Dr John A. Wagner

    Article first published online : 8 MAR 2013, DOI: 10.1177/0091270006289850

  18. A Thorough QTc Study to Assess the Effect of Sitagliptin, a DPP4 Inhibitor, on Ventricular Repolarization in Healthy Subjects

    The Journal of Clinical Pharmacology

    Volume 49, Issue 8, August 2009, Pages: 937–946, Dr Daniel M. Bloomfield, Dr Rajesh Krishna, David Hreniuk, Lisa Hickey, Kalyan Ghosh, Arthur J. Bergman, Jutta Miller, Maria J. Gutierrez, Randall Stoltz, Keith M. Gottesdiener, Gary A. Herman and John A. Wagner

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270009337511

  19. Saxagliptin and sitagliptin in adult patients with type 2 diabetes: a systematic review and meta-analysis

    Diabetes, Obesity and Metabolism

    Volume 14, Issue 6, June 2012, Pages: 481–492, K. R. Gerrald, E. Van Scoyoc, R. C. Wines, T. Runge and D. E. Jonas

    Article first published online : 27 DEC 2011, DOI: 10.1111/j.1463-1326.2011.01540.x

  20. You have free access to this content
    Efficacy and safety of sitagliptin and metformin as initial combination therapy and as monotherapy over 2 years in patients with type 2 diabetes

    Diabetes, Obesity and Metabolism

    Volume 12, Issue 5, May 2010, Pages: 442–451, D. Williams-Herman, J. Johnson, R. Teng, G. Golm, K. D. Kaufman, B. J. Goldstein and J. M. Amatruda

    Article first published online : 28 JAN 2010, DOI: 10.1111/j.1463-1326.2010.01204.x