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There are 1968 results for: content related to: An Efficient, Asymmetric Synthesis of Odanacatib, a Selective Inhibitor of Cathepsin K for the Treatment of Osteoporosis, Using an Enzyme-Mediated Dynamic Kinetic Resolution

  1. Development and validation of an RP-HPLC method for the quantitation of odanacatib in rat and human plasma and its application to a pharmacokinetic study

    Biomedical Chromatography

    Volume 29, Issue 11, November 2015, Pages: 1664–1669, Anitha Police, Sandip Gurav, Vinay Dhiman, Mohd Zainuddin, Ravi kanth Bhamidipati, Sriram Rajagopal and Ramesh Mullangi

    Version of Record online : 27 APR 2015, DOI: 10.1002/bmc.3476

  2. Prednisone has no effect on the pharmacokinetics of CYP3A4 metabolized drugs – midazolam and odanacatib

    The Journal of Clinical Pharmacology

    Volume 54, Issue 11, November 2014, Pages: 1280–1289, Eugene E. Marcantonio, Jeanine Ballard, Christopher R. Gibson, Kelem Kassahun, Jairam Palamanda, Cuyue Tang, Raymond Evers, Chengcheng Liu, Stefan Zajic, Chantal Mahon, Kate Mostoller, David Hreniuk, Anish Mehta, Denise Morris, John A. Wagner and S. Aubrey Stoch

    Version of Record online : 25 JUN 2014, DOI: 10.1002/jcph.338

  3. You have free access to this content
    Discontinuation of odanacatib and other osteoporosis treatments: Here today and gone tomorrow?

    Journal of Bone and Mineral Research

    Volume 26, Issue 2, February 2011, Pages: 239–241, Douglas C Bauer

    Version of Record online : 20 JAN 2011, DOI: 10.1002/jbmr.335

  4. You have free access to this content
    Odanacatib, a selective cathepsin K inhibitor to treat osteoporosis: safety, tolerability, pharmacokinetics and pharmacodynamics – results from single oral dose studies in healthy volunteers

    British Journal of Clinical Pharmacology

    Volume 75, Issue 5, May 2013, Pages: 1240–1254, S. Aubrey Stoch, Stefan Zajic, Julie A. Stone, Deborah L. Miller, Lucas van Bortel, Kenneth C. Lasseter, Barnali Pramanik, Caroline Cilissen, Qi Liu, Lida Liu, Boyd B. Scott, Deborah Panebianco, Yu Ding, Keith Gottesdiener and John A. Wagner

    Version of Record online : 8 APR 2013, DOI: 10.1111/j.1365-2125.2012.04471.x

  5. You have free access to this content
    Effects of Odanacatib on the Radius and Tibia of Postmenopausal Women: Improvements in Bone Geometry, Microarchitecture, and Estimated Bone Strength

    Journal of Bone and Mineral Research

    Volume 29, Issue 8, August 2014, Pages: 1786–1794, Angela M Cheung, Sharmila Majumdar, Kim Brixen, Roland Chapurlat, Thomas Fuerst, Klaus Engelke, Bernard Dardzinski, Antonio Cabal, Nadia Verbruggen, Shabana Ather, Elizabeth Rosenberg and Anne E de Papp

    Version of Record online : 21 JUL 2014, DOI: 10.1002/jbmr.2194

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    Odanacatib treatment increases hip bone mass and cortical thickness by preserving endocortical bone formation and stimulating periosteal bone formation in the ovariectomized adult rhesus monkey

    Journal of Bone and Mineral Research

    Volume 27, Issue 3, March 2012, Pages: 524–537, Tara Cusick, Charles M Chen, Brenda L Pennypacker, Maureen Pickarski, Donald B Kimmel, Boyd B Scott and Le T Duong

    Version of Record online : 21 FEB 2012, DOI: 10.1002/jbmr.1477

  7. Oxazolones

    Chemistry of Heterocyclic Compounds: Oxazoles, Volume 45

    Y. Shyamsunder Rao, Robert Filler, Pages: 361–729, 2008

    Published Online : 2 JAN 2008, DOI: 10.1002/9780470187289.ch3

  8. You have free access to this content
    Odanacatib Treatment Affects Trabecular and Cortical Bone in the Femur of Postmenopausal Women: Results of a Two-Year Placebo-Controlled Trial

    Journal of Bone and Mineral Research

    Volume 30, Issue 1, January 2015, Pages: 30–38, Klaus Engelke, Thomas Fuerst, Bernard Dardzinski, John Kornak, Shabana Ather, Harry K Genant and Anne de Papp

    Version of Record online : 26 DEC 2014, DOI: 10.1002/jbmr.2292

  9. Poster Session III (PIII 1–97) Displayed 7:00 am – 11:00 am Attended 7:00 am – 8:00 am

    Clinical Pharmacology & Therapeutics

    Volume 93, Issue S1, February 2013, Pages: S88–S122,

    Version of Record online : 22 FEB 2013, DOI: 10.1038/clpt.2012.258

    Corrected by:

    Corrigendum: Corrigendum: Review of In Vitro Transporter Data in Recently Approved New Drug Applications

    Vol. 93, Issue 4, 366, Version of Record online: 16 JAN 2013

  10. Emerging Therapies

    Osteoporosis: Diagnosis and Management

    Michael R. McClung, Cristiano A. F. Zerbini, Pages: 211–226, 2013

    Published Online : 2 AUG 2013, DOI: 10.1002/9781118316290.ch14

  11. You have free access to this content
    Odanacatib reduces bone turnover and increases bone mass in the lumbar spine of skeletally mature ovariectomized rhesus monkeys

    Journal of Bone and Mineral Research

    Volume 27, Issue 3, March 2012, Pages: 509–523, Patricia J Masarachia, Brenda L Pennypacker, Maureen Pickarski, Kevin R Scott, Gregg A Wesolowski, Susan Y Smith, Rani Samadfam, Jason E Goetzmann, Boyd B Scott, Donald B Kimmel and Le T Duong

    Version of Record online : 21 FEB 2012, DOI: 10.1002/jbmr.1475

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    Odanacatib, a cathepsin-K inhibitor for osteoporosis: A two-year study in postmenopausal women with low bone density

    Journal of Bone and Mineral Research

    Volume 25, Issue 5, May 2010, Pages: 937–947, Henry G Bone, Michael R McClung, Christian Roux, Robert R Recker, John A Eisman, Nadia Verbruggen, Carolyn M Hustad, Carolyn DaSilva, Arthur C Santora and B Avery Ince

    Version of Record online : 14 DEC 2009, DOI: 10.1359/jbmr.091035

  13. C-5′-Substituted Cinchona Alkaloid Derivatives Catalyse the First Highly Enantioselective Dynamic Kinetic Resolutions of Azlactones by Thiolysis

    European Journal of Organic Chemistry

    Volume 2013, Issue 24, August 2013, Pages: 5398–5413, Carole Palacio and Stephen J. Connon

    Version of Record online : 4 JUL 2013, DOI: 10.1002/ejoc.201300451

  14. Improvement of wood properties by impregnation with multifunctional monomers

    Journal of Applied Polymer Science

    Volume 42, Issue 1, 5 January 1991, Pages: 55–67, Lon J. Mathias, Soo Lee, John R. Wright and Stephen C. Warren

    Version of Record online : 10 MAR 2003, DOI: 10.1002/app.1991.070420107

  15. Highly Efficient Ring-Opening Reaction of Azlactone-Based Copolymer Platforms for the Design of Functionalized Materials

    Macromolecular Rapid Communications

    Volume 33, Issue 9, May 14, 2012, Pages: 848–855, Aurélie Laquièvre, Naomi S. Allaway, Joël Lyskawa, Patrice Woisel, Jean-Marc Lefebvre and David Fournier

    Version of Record online : 17 APR 2012, DOI: 10.1002/marc.201200063

  16. Mesoionic Oxazoles

    Chemistry of Heterocyclic Compounds: Oxazoles, Volume 45

    Henry L. Gingrich, Jonathan S. Baum, Pages: 731–961, 2008

    Published Online : 2 JAN 2008, DOI: 10.1002/9780470187289.ch4

  17. Oxazolones in Organocatalysis, New Tricks for an Old Reagent

    Chemistry – An Asian Journal

    Volume 6, Issue 3, March 1, 2011, Pages: 720–734, Andrea-Nekane R. Alba and Dr. Ramon Rios

    Version of Record online : 11 JAN 2011, DOI: 10.1002/asia.201000636

  18. Effect of the Cathepsin K Inhibitor Odanacatib on Bone Resorption Biomarkers in Healthy Postmenopausal Women: Two Double-Blind, Randomized, Placebo-Controlled Phase I Studies

    Clinical Pharmacology & Therapeutics

    Volume 86, Issue 2, August 2009, Pages: 175–182, SA Stoch, S Zajic, J Stone, DL Miller, K Van Dyck, MJ Gutierrez, M De Decker, L Liu, Q Liu, BB Scott, D Panebianco, B Jin, LT Duong, K Gottesdiener and JA Wagner

    Version of Record online : 6 MAY 2009, DOI: 10.1038/clpt.2009.60

  19. Synthesis of a Liquid Bisoxazolin-5-one by Radical Reaction of Bismercaptan onto 2-Ethenyloxazolin- 5-one

    Macromolecular Chemistry and Physics

    Volume 203, Issue 1, January 2002, Pages: 199–211, René Saint-Loup, Jean-Jacques Robin and Bernard Boutevin

    Version of Record online : 16 JAN 2002, DOI: 10.1002/1521-3935(20020101)203:1<199::AID-MACP199>3.0.CO;2-L

  20. Synthesis and properties of water-soluble azlactone copolymers

    Journal of Polymer Science Part A: Polymer Chemistry

    Volume 50, Issue 22, 15 November 2012, Pages: 4674–4685, Casandra M. Gardner, Carla E. Brown and Harald D. H. Stöver

    Version of Record online : 14 AUG 2012, DOI: 10.1002/pola.26281