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There are 4987 results for: content related to: HDDD2 is a familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions caused by a missense mutation in the signal peptide of progranulin

  1. Review: Recent progress in frontotemporal lobar degeneration

    Neuropathology and Applied Neurobiology

    Volume 36, Issue 1, February 2010, Pages: 4–16, S. M. Pickering-Brown

    Article first published online : 10 OCT 2009, DOI: 10.1111/j.1365-2990.2009.01045.x

  2. You have free access to this content
    Frontotemporal Lobar Degeneration: Current Concepts in the Light of Recent Advances

    Brain Pathology

    Volume 17, Issue 1, January 2007, Pages: 104–114, Samir Kumar-Singh and Christine Van Broeckhoven

    Article first published online : 26 FEB 2007, DOI: 10.1111/j.1750-3639.2007.00055.x

  3. ALS and FTLD: two faces of TDP-43 proteinopathy

    European Journal of Neurology

    Volume 15, Issue 8, August 2008, Pages: 772–780, R. M. Liscic, L. T. Grinberg, J. Zidar, M. A. Gitcho and N. J. Cairns

    Article first published online : 9 JUL 2008, DOI: 10.1111/j.1468-1331.2008.02195.x

  4. A quantitative study of the neuropathology of 32 sporadic and familial cases of frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP)

    Neuropathology and Applied Neurobiology

    Volume 38, Issue 1, February 2012, Pages: 25–38, R. A. Armstrong, D. Carter and N. J. Cairns

    Article first published online : 6 JAN 2012, DOI: 10.1111/j.1365-2990.2011.01188.x

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    Granulin mutations associated with frontotemporal lobar degeneration and related disorders: An update

    Human Mutation

    Volume 29, Issue 12, December 2008, Pages: 1373–1386, I. Gijselinck, C. Van Broeckhoven and M. Cruts

    Article first published online : 9 JUN 2008, DOI: 10.1002/humu.20785

  6. Review: Transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration

    Neuropathology and Applied Neurobiology

    Volume 36, Issue 2, April 2010, Pages: 97–112, T. F. Gendron, K. A. Josephs and L. Petrucelli

    Article first published online : 23 MAR 2010, DOI: 10.1111/j.1365-2990.2010.01060.x

  7. Molecular Genetics of Frontotemporal Dementia

    Standard Article

    eLS

    Raffaele Ferrari, Avinash Thumma and Parastoo Momeni

    Published Online : 15 MAY 2013, DOI: 10.1002/9780470015902.a0024457

  8. Mouse models of frontotemporal dementia

    Annals of Neurology

    Volume 72, Issue 6, December 2012, Pages: 837–849, Erik D. Roberson

    Article first published online : 31 DEC 2012, DOI: 10.1002/ana.23722

  9. Cellular ageing, increased mortality and FTLD-TDP-associated neuropathology in progranulin knockout mice

    The Journal of Pathology

    Volume 228, Issue 1, September 2012, Pages: 67–76, Hans Wils, Gernot Kleinberger, Sandra Pereson, Jonathan Janssens, Anja Capell, Debby Van Dam, Ivy Cuijt, Geert Joris, Peter P De Deyn, Christian Haass, Christine Van Broeckhoven and Samir Kumar-Singh

    Article first published online : 25 JUN 2012, DOI: 10.1002/path.4043

  10. Molecular characterization of novel progranulin (GRN) mutations in frontotemporal dementia

    Human Mutation

    Volume 29, Issue 4, April 2008, Pages: 512–521, Odity Mukherjee, Jun Wang, Michael Gitcho, Sumi Chakraverty, Lisa Taylor-Reinwald, Shantia Shears, John S.K. Kauwe, Joanne Norton, Denise Levitch, Eileen H. Bigio, Kimmo J. Hatanpaa, Charles L. White, John C. Morris, Nigel J. Cairns and Alison Goate

    Article first published online : 8 JAN 2008, DOI: 10.1002/humu.20681

  11. Frontotemporal Lobar Degeneration with TDP-43 Pathology

    Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders, Second Edition

    Ian R. A. Mackenzie, Manuela Neumann, Pages: 393–403, 2011

    Published Online : 21 SEP 2011, DOI: 10.1002/9781444341256.ch41

  12. Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy

    Neuropathology

    Volume 30, Issue 2, April 2010, Pages: 170–181, Tetsuaki Arai, Masato Hasegawa, Takashi Nonoka, Fuyuki Kametani, Makiko Yamashita, Masato Hosokawa, Kazuhiro Niizato, Kuniaki Tsuchiya, Zen Kobayashi, Kenji Ikeda, Mari Yoshida, Mitsumoto Onaya, Hiroshige Fujishiro and Haruhiko Akiyama

    Article first published online : 19 JAN 2010, DOI: 10.1111/j.1440-1789.2009.01089.x

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    Progranulin: normal function and role in neurodegeneration

    Journal of Neurochemistry

    Volume 104, Issue 2, January 2008, Pages: 287–297, Jason L. Eriksen and Ian R. A. Mackenzie

    Article first published online : 15 SEP 2007, DOI: 10.1111/j.1471-4159.2007.04968.x

  14. Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: A spectrum of TDP-43 proteinopathies

    Neuropathology

    Volume 30, Issue 2, April 2010, Pages: 103–112, Felix Geser, Virginia M.-Y. Lee and John Q. Trojanowski

    Article first published online : 20 JAN 2010, DOI: 10.1111/j.1440-1789.2009.01091.x

  15. Ubiquitinated, p62 immunopositive cerebellar cortical neuronal inclusions are evident across the spectrum of TDP-43 proteinopathies but are only rarely additionally immunopositive for phosphorylation-dependent TDP-43

    Neuropathology

    Volume 31, Issue 3, June 2011, Pages: 239–249, Andrew King, Satomi Maekawa, Istvan Bodi, Claire Troakes and Safa Al-Sarraj

    Article first published online : 1 DEC 2010, DOI: 10.1111/j.1440-1789.2010.01171.x

  16. Low prevalence of progranulin mutations in Finnish patients with frontotemporal lobar degeneration

    European Journal of Neurology

    Volume 16, Issue 1, January 2009, Pages: 27–30, J. Krüger, A.-L. Kaivorinne, B. Udd, K. Majamaa and A. M. Remes

    Article first published online : 25 NOV 2008, DOI: 10.1111/j.1468-1331.2008.02272.x

  17. Laminar distribution of the pathological changes in sporadic frontotemporal lobar degeneration with transactive response (TAR) DNA-binding protein of 43 kDa (TDP-43) proteinopathy: a quantitative study using polynomial curve fitting

    Neuropathology and Applied Neurobiology

    Volume 39, Issue 4, June 2013, Pages: 335–347, R. A. Armstrong, R. L. Hamilton, I. R. A. Mackenzie, J. Hedreen and N. J. Cairns

    Article first published online : 25 APR 2013, DOI: 10.1111/j.1365-2990.2012.01291.x

  18. Genetics of dementia: Update and guidelines for the clinician

    American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

    Volume 159B, Issue 6, September 2012, Pages: 628–643, Petra E. Cohn-Hokke, Mariet W. Elting, Yolande A.L. Pijnenburg and John C. van Swieten

    Article first published online : 19 JUL 2012, DOI: 10.1002/ajmg.b.32080

  19. Serum biomarker for progranulin-associated frontotemporal lobar degeneration

    Annals of Neurology

    Volume 65, Issue 5, May 2009, Pages: 603–609, Kristel Sleegers, Nathalie Brouwers, Philip Van Damme, Sebastiaan Engelborghs, Ilse Gijselinck, Julie van der Zee, Karin Peeters, Maria Mattheijssens, Marc Cruts, Rik Vandenberghe, Peter P. De Deyn, Wim Robberecht and Christine Van Broeckhoven

    Article first published online : 13 MAR 2009, DOI: 10.1002/ana.21621

  20. Progranulin gene mutation with an unusual clinical and neuropathologic presentation

    Movement Disorders

    Volume 23, Issue 8, 15 June 2008, Pages: 1168–1173, Christian Wider, Ryan J. Uitti, Zbigniew K. Wszolek, John Y. Fang, Keith A. Josephs, Matthew C. Baker, Rosa Rademakers, Michael L. Hutton and Dennis W. Dickson

    Article first published online : 28 APR 2008, DOI: 10.1002/mds.22065