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There are 7380 results for: content related to: TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease

  1. Review: Transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration

    Neuropathology and Applied Neurobiology

    Volume 36, Issue 2, April 2010, Pages: 97–112, T. F. Gendron, K. A. Josephs and L. Petrucelli

    Article first published online : 23 MAR 2010, DOI: 10.1111/j.1365-2990.2010.01060.x

  2. Detection of TDP-43 oligomers in frontotemporal lobar degeneration–TDP

    Annals of Neurology

    Volume 78, Issue 2, August 2015, Pages: 211–221, Patricia F. Kao, Yun-Ru Chen, Xiao-Bo Liu, Charles DeCarli, William W. Seeley and Lee-Way Jin

    Article first published online : 30 JUN 2015, DOI: 10.1002/ana.24431

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    Significance and limitation of the pathological classification of TDP-43 proteinopathy

    Neuropathology

    Volume 34, Issue 6, December 2014, Pages: 578–588, Tetsuaki Arai

    Article first published online : 8 SEP 2014, DOI: 10.1111/neup.12138

  4. Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy

    Neuropathology

    Volume 30, Issue 2, April 2010, Pages: 170–181, Tetsuaki Arai, Masato Hasegawa, Takashi Nonoka, Fuyuki Kametani, Makiko Yamashita, Masato Hosokawa, Kazuhiro Niizato, Kuniaki Tsuchiya, Zen Kobayashi, Kenji Ikeda, Mari Yoshida, Mitsumoto Onaya, Hiroshige Fujishiro and Haruhiko Akiyama

    Article first published online : 19 JAN 2010, DOI: 10.1111/j.1440-1789.2009.01089.x

  5. Abnormal TDP-43 expression is identified in the neocortex in cases of dementia pugilistica, but is mainly confined to the limbic system when identified in high and moderate stages of Alzheimer's disease

    Neuropathology

    Volume 30, Issue 4, August 2010, Pages: 408–419, Andrew King, Fiona Sweeney, Istvan Bodi, Claire Troakes, Satomi Maekawa and Safa Al-Sarraj

    Article first published online : 19 JAN 2010, DOI: 10.1111/j.1440-1789.2009.01085.x

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    TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration

    The FEBS Journal

    Volume 278, Issue 19, October 2011, Pages: 3550–3568, Fabienne C. Fiesel and Philipp J. Kahle

    Article first published online : 24 AUG 2011, DOI: 10.1111/j.1742-4658.2011.08258.x

  7. You have full text access to this OnlineOpen article
    Review: Prion-like mechanisms of transactive response DNA binding protein of 43 kDa (TDP-43) in amyotrophic lateral sclerosis (ALS)

    Neuropathology and Applied Neurobiology

    Volume 41, Issue 5, August 2015, Pages: 578–597, Phillip Smethurst, Katie Claire Louise Sidle and John Hardy

    Article first published online : 20 APR 2015, DOI: 10.1111/nan.12206

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    Spliceosome integrity is defective in the motor neuron diseases ALS and SMA

    EMBO Molecular Medicine

    Volume 5, Issue 2, February 2013, Pages: 221–234, Hitomi Tsuiji, Yohei Iguchi, Asako Furuya, Ayane Kataoka, Hiroyuki Hatsuta, Naoki Atsuta, Fumiaki Tanaka, Yoshio Hashizume, Hiroyasu Akatsu, Shigeo Murayama, Gen Sobue and Koji Yamanaka

    Article first published online : 25 JAN 2013, DOI: 10.1002/emmm.201202303

  9. Ubiquitinated, p62 immunopositive cerebellar cortical neuronal inclusions are evident across the spectrum of TDP-43 proteinopathies but are only rarely additionally immunopositive for phosphorylation-dependent TDP-43

    Neuropathology

    Volume 31, Issue 3, June 2011, Pages: 239–249, Andrew King, Satomi Maekawa, Istvan Bodi, Claire Troakes and Safa Al-Sarraj

    Article first published online : 1 DEC 2010, DOI: 10.1111/j.1440-1789.2010.01171.x

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    TDP-43: the relationship between protein aggregation and neurodegeneration in amyotrophic lateral sclerosis and frontotemporal lobar degeneration

    The FEBS Journal

    Volume 278, Issue 19, October 2011, Pages: 3539–3549, Robert H. Baloh

    Article first published online : 24 AUG 2011, DOI: 10.1111/j.1742-4658.2011.08256.x

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    Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking

    The EMBO Journal

    Volume 31, Issue 5, March 7, 2012, Pages: 1241–1252, Todd J Cohen, Andrew W Hwang, Travis Unger, John Q Trojanowski and Virginia M Y Lee

    Article first published online : 23 DEC 2011, DOI: 10.1038/emboj.2011.471

  12. p62/sequestosome 1 binds to TDP-43 in brains with frontotemporal lobar degeneration with TDP-43 inclusions

    Journal of Neuroscience Research

    Volume 90, Issue 10, October 2012, Pages: 2034–2042, Kunikazu Tanji, Hai-Xin Zhang, Fumiaki Mori, Akiyoshi Kakita, Hitoshi Takahashi and Koichi Wakabayashi

    Article first published online : 5 JUN 2012, DOI: 10.1002/jnr.23081

  13. Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: A spectrum of TDP-43 proteinopathies

    Neuropathology

    Volume 30, Issue 2, April 2010, Pages: 103–112, Felix Geser, Virginia M.-Y. Lee and John Q. Trojanowski

    Article first published online : 20 JAN 2010, DOI: 10.1111/j.1440-1789.2009.01091.x

  14. RNA-binding proteins in neurodegenerative disease: TDP-43 and beyond

    Wiley Interdisciplinary Reviews: RNA

    Volume 3, Issue 2, March/April 2012, Pages: 265–285, Keith A. Hanson, Sang Hwa Kim and Randal S. Tibbetts

    Article first published online : 25 OCT 2011, DOI: 10.1002/wrna.111

  15. No interaction between tau and TDP-43 pathologies in either frontotemporal lobar degeneration or motor neurone disease

    Neuropathology and Applied Neurobiology

    Volume 40, Issue 7, December 2014, Pages: 844–854, Andrew C. Robinson, Jennifer C. Thompson, Lindsey Weedon, Sara Rollinson, Stuart Pickering-Brown, Julie S. Snowden, Yvonne S. Davidson and David M. A. Mann

    Article first published online : 17 NOV 2014, DOI: 10.1111/nan.12155

  16. TDP-43 loss of function increases TFEB activity and blocks autophagosome–lysosome fusion

    The EMBO Journal

    Volume 35, Issue 2, 18 January 2016, Pages: 121–142, Qin Xia, Hongfeng Wang, Zongbing Hao, Cheng Fu, Qingsong Hu, Feng Gao, Haigang Ren, Dong Chen, Junhai Han, Zheng Ying and Guanghui Wang

    Article first published online : 23 DEC 2015, DOI: 10.15252/embj.201591998

  17. An MND/ALS phenotype associated with C9orf72 repeat expansion: Abundant p62-positive, TDP-43-negative inclusions in cerebral cortex, hippocampus and cerebellum but without associated cognitive decline

    Neuropathology

    Volume 32, Issue 5, October 2012, Pages: 505–514, Claire Troakes, Satomi Maekawa, Lokesh Wijesekera, Boris Rogelj, László Siklós, Christopher Bell, Bradley Smith, Stephen Newhouse, Caroline Vance, Lauren Johnson, Tibor Hortobágyi, Aleksey Shatunov, Ammar Al-Chalabi, Nigel Leigh, Christopher E. Shaw, Andrew King and Safa Al-Sarraj

    Article first published online : 19 DEC 2011, DOI: 10.1111/j.1440-1789.2011.01286.x

  18. Asparaginyl endopeptidase cleaves TDP-43 in brain

    PROTEOMICS

    Volume 12, Issue 15-16, August 2012, Pages: 2455–2463, Jeremy H. Herskowitz, Yair M. Gozal, Duc M. Duong, Eric B. Dammer, Marla Gearing, Keqiang Ye, James J. Lah, Junmin Peng, Allan I. Levey and Nicholas T. Seyfried

    Article first published online : 20 AUG 2012, DOI: 10.1002/pmic.201200006

  19. A quantitative study of the neuropathology of 32 sporadic and familial cases of frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP)

    Neuropathology and Applied Neurobiology

    Volume 38, Issue 1, February 2012, Pages: 25–38, R. A. Armstrong, D. Carter and N. J. Cairns

    Article first published online : 6 JAN 2012, DOI: 10.1111/j.1365-2990.2011.01188.x

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    What is the key player in TDP-43 pathology in ALS: Disappearance from the nucleus or inclusion formation in the cytoplasm?

    Neurology and Clinical Neuroscience

    Volume 1, Issue 1, January 2013, Pages: 11–17, Osamu Onodera, Akihiro Sugai, Takuya Konno, Mari Tada, Akihide Koyama and Masatoyo Nishizawa

    Article first published online : 31 JAN 2013, DOI: 10.1002/ncn3.9