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There are 3622 results for: content related to: Nuclear transport impairment of amyotrophic lateral sclerosis-linked mutations in FUS/TLS

  1. RNA-binding proteins in neurodegenerative disease: TDP-43 and beyond

    Wiley Interdisciplinary Reviews: RNA

    Volume 3, Issue 2, March/April 2012, Pages: 265–285, Keith A. Hanson, Sang Hwa Kim and Randal S. Tibbetts

    Version of Record online : 25 OCT 2011, DOI: 10.1002/wrna.111

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    Altered mRNP granule dynamics in FTLD pathogenesis

    Journal of Neurochemistry

    Volume 138, Issue S1, August 2016, Pages: 112–133, Hilary A. Bowden and Dorothee Dormann

    Version of Record online : 15 JUN 2016, DOI: 10.1111/jnc.13601

  3. Ubiquitinated, p62 immunopositive cerebellar cortical neuronal inclusions are evident across the spectrum of TDP-43 proteinopathies but are only rarely additionally immunopositive for phosphorylation-dependent TDP-43


    Volume 31, Issue 3, June 2011, Pages: 239–249, Andrew King, Satomi Maekawa, Istvan Bodi, Claire Troakes and Safa Al-Sarraj

    Version of Record online : 1 DEC 2010, DOI: 10.1111/j.1440-1789.2010.01171.x

  4. You have full text access to this OnlineOpen article
    Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss

    The EMBO Journal

    Volume 35, Issue 10, 17 May 2016, Pages: 1077–1097, Jelena Scekic-Zahirovic, Oliver Sendscheid, Hajer El Oussini, Mélanie Jambeau, Ying Sun, Sina Mersmann, Marina Wagner, Stéphane Dieterlé, Jérome Sinniger, Sylvie Dirrig-Grosch, Kevin Drenner, Marie-Christine Birling, Jinsong Qiu, Yu Zhou, Hairi Li, Xiang-Dong Fu, Caroline Rouaux, Tatyana Shelkovnikova, Anke Witting, Albert C Ludolph, Friedemann Kiefer, Erik Storkebaum, Clotilde Lagier-Tourenne and Luc Dupuis

    Version of Record online : 8 MAR 2016, DOI: 10.15252/embj.201592559

  5. Transportin 1 accumulates in FUS inclusions in adult-onset ALS without FUS mutation

    Neuropathology and Applied Neurobiology

    Volume 39, Issue 5, August 2013, Pages: 580–584, R. Takeuchi, Y. Toyoshima, M. Tada, A. Shiga, H. Tanaka, M. Shimohata, K. Kimura, T. Morita, A. Kakita, M. Nishizawa and H. Takahashi

    Version of Record online : 9 JUL 2013, DOI: 10.1111/nan.12022

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    Stress granules in neurodegeneration – lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma

    The FEBS Journal

    Volume 280, Issue 18, September 2013, Pages: 4348–4370, Eva Bentmann, Christian Haass and Dorothee Dormann

    Version of Record online : 9 MAY 2013, DOI: 10.1111/febs.12287

  7. Higher Prevalence of TDP-43 Proteinopathy in Cognitively Normal Asians: A Clinicopathological Study on a Multiethnic Sample

    Brain Pathology

    Volume 26, Issue 2, March 2016, Pages: 177–185, Camila Nascimento, Claudia K. Suemoto, Roberta D. Rodriguez, Ana Tereza Di Lorenzo Alho, Renata P. Leite, Jose Marcelo Farfel, Carlos Augusto Gonçalves Pasqualucci, Wilson Jacob-Filho and Lea T. Grinberg

    Version of Record online : 17 SEP 2015, DOI: 10.1111/bpa.12296

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    Prion-like propagation as a pathogenic principle in frontotemporal dementia

    Journal of Neurochemistry

    Volume 138, Issue S1, August 2016, Pages: 163–183, Eva-Maria Hock and Magdalini Polymenidou

    Version of Record online : 9 AUG 2016, DOI: 10.1111/jnc.13668

  9. Frontotemporal lobar degeneration: Pathogenesis, pathology and pathways to phenotype

    Brain Pathology

    David M.A. Mann and Julie S. Snowden

    Version of Record online : 2 MAR 2017, DOI: 10.1111/bpa.12486

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    TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration

    The FEBS Journal

    Volume 278, Issue 19, October 2011, Pages: 3550–3568, Fabienne C. Fiesel and Philipp J. Kahle

    Version of Record online : 24 AUG 2011, DOI: 10.1111/j.1742-4658.2011.08258.x

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    A yeast model of optineurin proteinopathy reveals a unique aggregation pattern associated with cellular toxicity

    Molecular Microbiology

    Volume 86, Issue 6, December 2012, Pages: 1531–1547, Dmitry Kryndushkin, Gudrun Ihrke, Tetsade C. Piermartiri and Frank Shewmaker

    Version of Record online : 9 NOV 2012, DOI: 10.1111/mmi.12075

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    Adenoviral expression of TDP-43 and FUS genes and shRNAs for protein degradation pathways in rodent motoneurons in vitro and in vivo


    Volume 34, Issue 1, February 2014, Pages: 83–98, Kazuhiko Watabe, Keiko Akiyama, Emiko Kawakami, Tomohiro Ishii, Kentaro Endo, Hiroko Yanagisawa, Kazunori Sango and Masami Tsukamoto

    Version of Record online : 12 AUG 2013, DOI: 10.1111/neup.12058

  13. RNA quality control and protein aggregates in amyotrophic lateral sclerosis: A review

    Muscle & Nerve

    Volume 47, Issue 3, March 2013, Pages: 330–338, Ashok Verma and Rup Tandan

    Version of Record online : 4 FEB 2013, DOI: 10.1002/mus.23673

  14. TARDBP and FUS Mutations Associated with Amyotrophic Lateral Sclerosis: Summary and Update

    Human Mutation

    Volume 34, Issue 6, June 2013, Pages: 812–826, Serena Lattante, Guy A. Rouleau and Edor Kabashi

    Version of Record online : 29 APR 2013, DOI: 10.1002/humu.22319

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    Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS

    The EMBO Journal

    Volume 31, Issue 22, November 14, 2012, Pages: 4258–4275, Dorothee Dormann, Tobias Madl, Chiara F Valori, Eva Bentmann, Sabina Tahirovic, Claudia Abou-Ajram, Elisabeth Kremmer, Olaf Ansorge, Ian R A Mackenzie, Manuela Neumann and Christian Haass

    Version of Record online : 11 SEP 2012, DOI: 10.1038/emboj.2012.261

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    Regulation of TDP-43 aggregation by phosphorylation andp62/SQSTM1

    Journal of Neurochemistry

    Volume 116, Issue 2, January 2011, Pages: 248–259, Owen A. Brady, Peter Meng, Yanqiu Zheng, Yuxin Mao and Fenghua Hu

    Version of Record online : 2 DEC 2010, DOI: 10.1111/j.1471-4159.2010.07098.x

  17. You have full text access to this OnlineOpen article
    Dysregulated axonal RNA translation in amyotrophic lateral sclerosis

    Wiley Interdisciplinary Reviews: RNA

    Volume 7, Issue 5, September/October 2016, Pages: 589–603, Kyota Yasuda and Stavroula Mili

    Version of Record online : 31 MAR 2016, DOI: 10.1002/wrna.1352

  18. Prevalence of transactive response DNA-binding protein 43 (TDP-43) proteinopathy in cognitively normal older adults: systematic review and meta-analysis

    Neuropathology and Applied Neurobiology

    C. Nascimento, A. T. Di Lorenzo Alho, C. Bazan Conceição Amaral, R. E. P. Leite, R. Nitrini, W. Jacob-Filho, C. A. Pasqualucci, S. R. K. Hokkanen, S. Hunter, H. Keage, G. G. Kovacs, L. T. Grinberg and C. K. Suemoto

    Version of Record online : 20 SEP 2017, DOI: 10.1111/nan.12430

  19. FUS-Immunoreactive Intranuclear Inclusions in Neurodegenerative Disease

    Brain Pathology

    Volume 20, Issue 3, May 2010, Pages: 589–597, John Woulfe, Douglas A. Gray and Ian R.A. Mackenzie

    Version of Record online : 21 SEP 2009, DOI: 10.1111/j.1750-3639.2009.00337.x

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    Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity

    The EMBO Journal

    Zachary Monahan, Veronica H Ryan, Abigail M Janke, Kathleen A Burke, Shannon N Rhoads, Gül H Zerze, Robert O'Meally, Gregory L Dignon, Alexander E Conicella, Wenwei Zheng, Robert B Best, Robert N Cole, Jeetain Mittal, Frank Shewmaker and Nicolas L Fawzi

    Version of Record online : 8 AUG 2017, DOI: 10.15252/embj.201696394