Search Results

There are 8593 results for: content related to: Nuclear transport impairment of amyotrophic lateral sclerosis-linked mutations in FUS/TLS

  1. You have free access to this content
    Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS

    The EMBO Journal

    Volume 31, Issue 22, November 14, 2012, Pages: 4258–4275, Dorothee Dormann, Tobias Madl, Chiara F Valori, Eva Bentmann, Sabina Tahirovic, Claudia Abou-Ajram, Elisabeth Kremmer, Olaf Ansorge, Ian R A Mackenzie, Manuela Neumann and Christian Haass

    Article first published online : 11 SEP 2012, DOI: 10.1038/emboj.2012.261

  2. You have free access to this content
    ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

    The EMBO Journal

    Volume 29, Issue 16, August 18, 2010, Pages: 2841–2857, Dorothee Dormann, Ramona Rodde, Dieter Edbauer, Eva Bentmann, Ingeborg Fischer, Alexander Hruscha, Manuel E Than, Ian R A Mackenzie, Anja Capell, Bettina Schmid, Manuela Neumann and Christian Haass

    Article first published online : 6 JUL 2010, DOI: 10.1038/emboj.2010.143

  3. You have free access to this content
    TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration

    FEBS Journal

    Volume 278, Issue 19, October 2011, Pages: 3550–3568, Fabienne C. Fiesel and Philipp J. Kahle

    Article first published online : 24 AUG 2011, DOI: 10.1111/j.1742-4658.2011.08258.x

  4. FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis

    Annals of Neurology

    Volume 67, Issue 6, June 2010, Pages: 739–748, Han-Xiang Deng, Hong Zhai, Eileen H. Bigio, Jianhua Yan, Faisal Fecto, Kaouther Ajroud, Manjari Mishra, Senda Ajroud-Driss, Scott Heller, Robert Sufit, Nailah Siddique, Enrico Mugnaini and Teepu Siddique

    Article first published online : 14 APR 2010, DOI: 10.1002/ana.22051

  5. FUS-Immunoreactive Intranuclear Inclusions in Neurodegenerative Disease

    Brain Pathology

    Volume 20, Issue 3, May 2010, Pages: 589–597, John Woulfe, Douglas A. Gray and Ian R.A. Mackenzie

    Article first published online : 21 SEP 2009, DOI: 10.1111/j.1750-3639.2009.00337.x

  6. You have free access to this content
    Stress granules in neurodegeneration – lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma

    FEBS Journal

    Volume 280, Issue 18, September 2013, Pages: 4348–4370, Eva Bentmann, Christian Haass and Dorothee Dormann

    Article first published online : 9 MAY 2013, DOI: 10.1111/febs.12287

  7. You have free access to this content
    Loss of fused in sarcoma (FUS) promotes pathological Tau splicing

    EMBO reports

    Volume 13, Issue 8, August 2012, Pages: 759–764, Denise Orozco, Sabina Tahirovic, Kristin Rentzsch, Benjamin M Schwenk, Christian Haass and Dieter Edbauer

    Article first published online : 19 JUN 2012, DOI: 10.1038/embor.2012.90

  8. FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stress

    Journal of Cellular Physiology

    Volume 228, Issue 11, November 2013, Pages: 2222–2231, Reddy Ranjith K. Sama, Catherine L. Ward, Laura J. Kaushansky, Nathan Lemay, Shinsuke Ishigaki, Fumihiko Urano and Daryl A. Bosco

    Article first published online : 25 JUL 2013, DOI: 10.1002/jcp.24395

  9. You have free access to this content
    Transportin 1 colocalization with Fused in Sarcoma (FUS) inclusions is not characteristic for amyotrophic lateral sclerosis-FUS confirming disrupted nuclear import of mutant FUS and distinguishing it from frontotemporal lobar degeneration with FUS inclusions

    Neuropathology and Applied Neurobiology

    Volume 39, Issue 5, August 2013, Pages: 553–561, C. Troakes, T. Hortobágyi, C. Vance, S. Al-Sarraj, B. Rogelj and C. E. Shaw

    Article first published online : 9 JUL 2013, DOI: 10.1111/j.1365-2990.2012.01300.x

  10. You have free access to this content
    TLS/FUS, a pro-oncogene involved in multiple chromosomal translocations, is a novel regulator of BCR/ABL-mediated leukemogenesis

    The EMBO Journal

    Volume 17, Issue 15, August 3, 1998, Pages: 4442–4455, Danilo Perrotti, Silvia Bonatti, Rossana Trotta, Robert Martinez, Tomasz Skorski, Paolo Salomoni, Emanuela Grassilli, Renato V. Iozzo, Denise R. Cooper and Bruno Calabretta

    Article first published online : 3 AUG 1998, DOI: 10.1093/emboj/17.15.4442

  11. RNA-binding proteins in neurodegenerative disease: TDP-43 and beyond

    Wiley Interdisciplinary Reviews: RNA

    Volume 3, Issue 2, March/April 2012, Pages: 265–285, Keith A. Hanson, Sang Hwa Kim and Randal S. Tibbetts

    Article first published online : 25 OCT 2011, DOI: 10.1002/wrna.111

  12. You have free access to this content
    FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment

    The EMBO Journal

    Volume 31, Issue 24, December 12, 2012, Pages: 4502–4510, Mariangela Morlando, Stefano Dini Modigliani, Giulia Torrelli, Alessandro Rosa, Valerio Di Carlo, Elisa Caffarelli and Irene Bozzoni

    Article first published online : 12 DEC 2012, DOI: 10.1038/emboj.2012.319

  13. You have free access to this content
    The FUS about arginine methylation in ALS and FTLD

    The EMBO Journal

    Volume 31, Issue 22, November 14, 2012, Pages: 4249–4251, Hannah M Kaneb, Patrick A Dion and Guy A Rouleau

    Article first published online : 19 OCT 2012, DOI: 10.1038/emboj.2012.291

  14. Unusual clinical presentation and neuropathology in two subjects with fused-in sarcoma (FUS) positive inclusions

    Neuropathology

    Volume 32, Issue 1, February 2012, Pages: 60–68, Päivi H. Hartikainen, Maria Pikkarainen, Tuomo Hänninen, Hilkka Soininen and Irina Alafuzoff

    Article first published online : 26 APR 2011, DOI: 10.1111/j.1440-1789.2011.01218.x

  15. You have free access to this content
    FUS-CHOP Fusion Protein Expression Coupled to p53 Deficiency Induces Liposarcoma in Mouse but Not in Human Adipose-Derived Mesenchymal Stem/Stromal Cells

    STEM CELLS

    Volume 29, Issue 2, February 2011, Pages: 179–192, Rene Rodriguez, Ruth Rubio, Ivan Gutierrez-Aranda, Gustavo J. Melen, Carolina Elosua, Javier García-Castro and Pablo Menendez

    Article first published online : 24 FEB 2011, DOI: 10.1002/stem.571

  16. Nuclear carrier and RNA-binding proteins in frontotemporal lobar degeneration associated with fused in sarcoma (FUS) pathological changes

    Neuropathology and Applied Neurobiology

    Volume 39, Issue 2, February 2013, Pages: 157–165, Y. S. Davidson, A. C. Robinson, Q. Hu, M. Mishra, A. Baborie, E. Jaros, R. H. Perry, N. J. Cairns, A. Richardson, A. Gerhard, D. Neary, J. S. Snowden, E. H. Bigio and D. M. A. Mann

    Article first published online : 25 JAN 2013, DOI: 10.1111/j.1365-2990.2012.01274.x

  17. You have free access to this content
    Adenoviral expression of TDP-43 and FUS genes and shRNAs for protein degradation pathways in rodent motoneurons in vitro and in vivo

    Neuropathology

    Volume 34, Issue 1, February 2014, Pages: 83–98, Kazuhiko Watabe, Keiko Akiyama, Emiko Kawakami, Tomohiro Ishii, Kentaro Endo, Hiroko Yanagisawa, Kazunori Sango and Masami Tsukamoto

    Article first published online : 12 AUG 2013, DOI: 10.1111/neup.12058

  18. A mechanistic study on the metastasis inducing function of FUS-CHOP fusion protein in liposarcoma

    International Journal of Cancer

    Volume 134, Issue 12, 15 June 2014, Pages: 2808–2819, Nitin Patil, Suhail Ahmed Kabeer Rasheed, Mohammed Abba, Jörg Hendrik Leupold, Matthias Schwarzbach and Heike Allgayer

    Article first published online : 7 DEC 2013, DOI: 10.1002/ijc.28638

  19. Basophilic inclusions and neuronal intermediate filament inclusions in amyotrophic lateral sclerosis and frontotemporal lobar degeneration

    Neuropathology

    Volume 34, Issue 6, December 2014, Pages: 589–595, Hidefumi Ito

    Article first published online : 27 MAR 2014, DOI: 10.1111/neup.12119

  20. You have full text access to this OnlineOpen article
    Spliceosome integrity is defective in the motor neuron diseases ALS and SMA

    EMBO Molecular Medicine

    Volume 5, Issue 2, February 2013, Pages: 221–234, Hitomi Tsuiji, Yohei Iguchi, Asako Furuya, Ayane Kataoka, Hiroyuki Hatsuta, Naoki Atsuta, Fumiaki Tanaka, Yoshio Hashizume, Hiroyasu Akatsu, Shigeo Murayama, Gen Sobue and Koji Yamanaka

    Article first published online : 25 JAN 2013, DOI: 10.1002/emmm.201202303