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There are 17382 results for: content related to: Transcriptional regulation of βsecretase-1 by 12/15-lipoxygenase results in enhanced amyloidogenesis and cognitive impairments

  1. You have full text access to this Open Access content
    SCFFbx2-E3-ligase-mediated degradation of BACE1 attenuates Alzheimer’s disease amyloidosis and improves synaptic function

    Aging Cell

    Volume 9, Issue 6, December 2010, Pages: 1018–1031, Bing Gong, Fei Chen, Yong Pan, Isabel Arrieta-Cruz, Yukiko Yoshida, Vahram Haroutunian and Giulio M. Pasinetti

    Version of Record online : 29 OCT 2010, DOI: 10.1111/j.1474-9726.2010.00632.x

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    Behavioral phenotypes of amyloid-based genetically modified mouse models of Alzheimer's disease

    Genes, Brain and Behavior

    Volume 4, Issue 3, April 2005, Pages: 173–196, D. T. Kobayashi and K. S. Chen

    Version of Record online : 18 MAR 2005, DOI: 10.1111/j.1601-183X.2005.00124.x

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    Obovatol improves cognitive functions in animal models for Alzheimer’s disease

    Journal of Neurochemistry

    Volume 120, Issue 6, March 2012, Pages: 1048–1059, Dong-Young Choi, Jae Woong Lee, Jin Peng, Young Jung Lee, Jin-Yi Han, Yeon Hee Lee, Im Seop Choi, Sang Bae Han, Jae Kyung Jung, Woong Soo Lee, Seung-Ho Lee, Byoung-Mog Kwon, Ki-Wan Oh and Jin Tae Hong

    Version of Record online : 10 FEB 2012, DOI: 10.1111/j.1471-4159.2011.07642.x

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    β-Site APP-cleaving enzyme 1 trafficking and Alzheimer’s disease pathogenesis

    Journal of Neurochemistry

    Volume 120, Issue 6, March 2012, Pages: 869–880, Jiangli Tan and Geneviève Evin

    Version of Record online : 23 JAN 2012, DOI: 10.1111/j.1471-4159.2011.07623.x

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    Transcriptional and post-transcriptional regulation of β-secretase

    IUBMB Life

    Volume 64, Issue 12, December 2012, Pages: 943–950, Elena Tamagno, M. Guglielmotto, D. Monteleone, A. Vercelli and M. Tabaton

    Version of Record online : 26 NOV 2012, DOI: 10.1002/iub.1099

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    12/15-Lipoxygenase Products Induce Inflammation and Impair Insulin Signaling in 3T3-L1 Adipocytes

    Obesity

    Volume 17, Issue 9, September 2009, Pages: 1657–1663, Swarup K. Chakrabarti, Banumathi K. Cole, Yeshao Wen, Susanna R. Keller and Jerry L. Nadler

    Version of Record online : 6 SEP 2012, DOI: 10.1038/oby.2009.192

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    Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling

    Aging Cell

    Volume 7, Issue 2, April 2008, Pages: 137–147, Hyun Jin Cho, Seok Min Jin, Hong Deuk Youn, Kyoon Huh and Inhee Mook-Jung

    Version of Record online : 7 DEC 2007, DOI: 10.1111/j.1474-9726.2007.00360.x

  8. Functional deprivation promotes amyloid plaque pathogenesis in Tg2576 mouse olfactory bulb and piriform cortex

    European Journal of Neuroscience

    Volume 31, Issue 4, February 2010, Pages: 710–721, Xue-Mei Zhang, Kun Xiong, Yan Cai, Huaibin Cai, Xue-Gang Luo, Jia-Chun Feng, Richard W. Clough, Peter R. Patrylo, Robert G. Struble and Xiao-Xin Yan

    Version of Record online : 11 FEB 2010, DOI: 10.1111/j.1460-9568.2010.07103.x

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    Size and sulfation are critical for the effect of heparin on APP processing and Aβ production

    Journal of Neurochemistry

    Volume 123, Issue 3, November 2012, Pages: 447–457, Hao Cui, Amos C. Hung, Craig Freeman, Christian Narkowicz, Glenn A. Jacobson and David H. Small

    Version of Record online : 21 SEP 2012, DOI: 10.1111/j.1471-4159.2012.07929.x

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    Revisiting the peripheral sink hypothesis: inhibiting BACE1 activity in the periphery does not alter β-amyloid levels in the CNS

    Journal of Neurochemistry

    Volume 132, Issue 4, February 2015, Pages: 477–486, Biljana Georgievska, Susanne Gustavsson, Johan Lundkvist, Jan Neelissen, Susanna Eketjäll, Veronica Ramberg, Tjerk Bueters, Karin Agerman, Anders Juréus, Samuel Svensson, Stefan Berg, Johanna Fälting and Urban Lendahl

    Version of Record online : 18 SEP 2014, DOI: 10.1111/jnc.12937

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    The 12-15-lipoxygenase is a modulator of Alzheimer's-related tau pathology in vivo

    Aging Cell

    Volume 12, Issue 6, December 2013, Pages: 1082–1090, Phillip F. Giannopoulos, Yash B. Joshi, Jin Chu and Domenico Praticò

    Version of Record online : 19 AUG 2013, DOI: 10.1111/acel.12136

  12. Astrocytic expression of the Alzheimer's disease β-secretase (BACE1) is stimulus-dependent

    Glia

    Volume 41, Issue 2, 15 January 2003, Pages: 169–179, Maike Hartlage-Rübsamen, Ulrike Zeitschel, Jenny Apelt, Ulrich Gärtner, Heike Franke, Tobias Stahl, Albrecht Günther, Reinhard Schliebs, Milena Penkowa, Volker Bigl and Steffen Roßner

    Version of Record online : 28 DEC 2002, DOI: 10.1002/glia.10178

  13. IFN-γ-induced BACE1 expression is mediated by activation of JAK2 and ERK1/2 signaling pathways and direct binding of STAT1 to BACE1 promoter in astrocytes

    Glia

    Volume 55, Issue 3, February 2007, Pages: 253–262, Hyun Jin Cho, Su-Kyoung Kim, Seok Min Jin, Eun-Mi Hwang, Yong Sik Kim, Kyoon Huh and Inhee Mook-Jung

    Version of Record online : 7 NOV 2006, DOI: 10.1002/glia.20451

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    Interaction between cytokines and inflammatory cells in islet dysfunction, insulin resistance and vascular disease

    Diabetes, Obesity and Metabolism

    Volume 15, Issue s3, September 2013, Pages: 117–129, Y. Imai, A. D. Dobrian, J. R. Weaver, M. J. Butcher, B. K. Cole, E. V. Galkina, M. A. Morris, D. A. Taylor-Fishwick and J. L. Nadler

    Version of Record online : 4 SEP 2013, DOI: 10.1111/dom.12161

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    Disruption of the 12/15-lipoxygenase gene (Alox15) protects hyperlipidemic mice from nonalcoholic fatty liver disease

    Hepatology

    Volume 52, Issue 6, December 2010, Pages: 1980–1991, Marcos Martínez-Clemente, Natàlia Ferré, Esther Titos, Raquel Horrillo, Ana González-Périz, Eva Morán-Salvador, Cristina López-Vicario, Rosa Miquel, Vicente Arroyo, Colin D. Funk and Joan Clària

    Version of Record online : 21 OCT 2010, DOI: 10.1002/hep.23928

  16. Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease

    Glia

    Volume 58, Issue 3, February 2010, Pages: 300–314, Takashi Mori, Naoki Koyama, Gary W. Arendash, Yuko Horikoshi-Sakuraba, Jun Tan and Terrence Town

    Version of Record online : 24 AUG 2009, DOI: 10.1002/glia.20924

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    A role for 12/15 lipoxygenase in the amyloid β precursor protein metabolism

    Journal of Neurochemistry

    Volume 103, Issue 1, October 2007, Pages: 380–387, Francesca Succol and Domenico Praticò

    Version of Record online : 3 JUN 2007, DOI: 10.1111/j.1471-4159.2007.04742.x

  18. Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1

    European Journal of Neuroscience

    Volume 23, Issue 1, January 2006, Pages: 251–260, Masuo Ohno, Lei Chang, Wilbur Tseng, Holly Oakley, Martin Citron, William L. Klein, Robert Vassar and John F. Disterhoft

    Version of Record online : 18 JAN 2006, DOI: 10.1111/j.1460-9568.2005.04551.x

  19. Approaches to Amyloid Therapies for the Treatment of Alzheimer's Disease

    Standard Article

    Burger's Medicinal Chemistry and Drug Discovery

    Albert J. Robichaud, Ji-In Kim and J. Steven Jacobsen

    Published Online : 15 SEP 2010, DOI: 10.1002/0471266949.bmc249

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    APPswe/Aβ regulation of osteoclast activation and RAGE expression in an age-dependent manner

    Journal of Bone and Mineral Research

    Volume 26, Issue 5, May 2011, Pages: 1084–1098, Shun Cui, Fei Xiong, Yan Hong, Ji-Ung Jung, Xing-Sheng Li, Jian-Zhong Liu, Riqiang Yan, Lin Mei, Xu Feng and Wen-Cheng Xiong

    Version of Record online : 3 MAY 2011, DOI: 10.1002/jbmr.299