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There are 22573 results for: content related to: Transcriptional regulation of βsecretase-1 by 12/15-lipoxygenase results in enhanced amyloidogenesis and cognitive impairments

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    Interaction between cytokines and inflammatory cells in islet dysfunction, insulin resistance and vascular disease

    Diabetes, Obesity and Metabolism

    Volume 15, Issue s3, September 2013, Pages: 117–129, Y. Imai, A. D. Dobrian, J. R. Weaver, M. J. Butcher, B. K. Cole, E. V. Galkina, M. A. Morris, D. A. Taylor-Fishwick and J. L. Nadler

    Article first published online : 4 SEP 2013, DOI: 10.1111/dom.12161

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    Disruption of the 12/15-lipoxygenase gene (Alox15) protects hyperlipidemic mice from nonalcoholic fatty liver disease

    Hepatology

    Volume 52, Issue 6, December 2010, Pages: 1980–1991, Marcos Martínez-Clemente, Natàlia Ferré, Esther Titos, Raquel Horrillo, Ana González-Périz, Eva Morán-Salvador, Cristina López-Vicario, Rosa Miquel, Vicente Arroyo, Colin D. Funk and Joan Clària

    Article first published online : 21 OCT 2010, DOI: 10.1002/hep.23928

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    The 12-15-lipoxygenase is a modulator of Alzheimer's-related tau pathology in vivo

    Aging Cell

    Volume 12, Issue 6, December 2013, Pages: 1082–1090, Phillip F. Giannopoulos, Yash B. Joshi, Jin Chu and Domenico Praticò

    Article first published online : 19 AUG 2013, DOI: 10.1111/acel.12136

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    12/15-Lipoxygenase Products Induce Inflammation and Impair Insulin Signaling in 3T3-L1 Adipocytes

    Obesity

    Volume 17, Issue 9, September 2009, Pages: 1657–1663, Swarup K. Chakrabarti, Banumathi K. Cole, Yeshao Wen, Susanna R. Keller and Jerry L. Nadler

    Article first published online : 6 SEP 2012, DOI: 10.1038/oby.2009.192

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    APPswe/Aβ regulation of osteoclast activation and RAGE expression in an age-dependent manner

    Journal of Bone and Mineral Research

    Volume 26, Issue 5, May 2011, Pages: 1084–1098, Shun Cui, Fei Xiong, Yan Hong, Ji-Ung Jung, Xing-Sheng Li, Jian-Zhong Liu, Riqiang Yan, Lin Mei, Xu Feng and Wen-Cheng Xiong

    Article first published online : 3 MAY 2011, DOI: 10.1002/jbmr.299

  6. Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease

    Glia

    Volume 58, Issue 3, February 2010, Pages: 300–314, Takashi Mori, Naoki Koyama, Gary W. Arendash, Yuko Horikoshi-Sakuraba, Jun Tan and Terrence Town

    Article first published online : 24 AUG 2009, DOI: 10.1002/glia.20924

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    Behavioral phenotypes of amyloid-based genetically modified mouse models of Alzheimer's disease

    Genes, Brain and Behavior

    Volume 4, Issue 3, April 2005, Pages: 173–196, D. T. Kobayashi and K. S. Chen

    Article first published online : 18 MAR 2005, DOI: 10.1111/j.1601-183X.2005.00124.x

  8. Transthyretin Accelerates Vascular Aβ Deposition in a Mouse Model of Alzheimer's Disease

    Brain Pathology

    Volume 19, Issue 1, January 2009, Pages: 48–57, Henny Wati, Takeshi Kawarabayashi, Etsuro Matsubara, Ayumi Kasai, Takae Hirasawa, Takeo Kubota, Yasuo Harigaya, Mikio Shoji and Shuichiro Maeda

    Article first published online : 22 APR 2008, DOI: 10.1111/j.1750-3639.2008.00166.x

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    Obovatol improves cognitive functions in animal models for Alzheimer’s disease

    Journal of Neurochemistry

    Volume 120, Issue 6, March 2012, Pages: 1048–1059, Dong-Young Choi, Jae Woong Lee, Jin Peng, Young Jung Lee, Jin-Yi Han, Yeon Hee Lee, Im Seop Choi, Sang Bae Han, Jae Kyung Jung, Woong Soo Lee, Seung-Ho Lee, Byoung-Mog Kwon, Ki-Wan Oh and Jin Tae Hong

    Article first published online : 10 FEB 2012, DOI: 10.1111/j.1471-4159.2011.07642.x

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    Insulin-like growth factor 2 reverses memory and synaptic deficits in APP transgenic mice

    EMBO Molecular Medicine

    Volume 6, Issue 10, October 2014, Pages: 1246–1262, Maria Pascual-Lucas, Silvia Viana da Silva, Marianna Di Scala, Carolina Garcia-Barroso, Gloria González-Aseguinolaza, Christophe Mulle, Cristina M Alberini, Mar Cuadrado-Tejedor and Ana Garcia-Osta

    Article first published online : 7 AUG 2014, DOI: 10.15252/emmm.201404228

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    SCFFbx2-E3-ligase-mediated degradation of BACE1 attenuates Alzheimer’s disease amyloidosis and improves synaptic function

    Aging Cell

    Volume 9, Issue 6, December 2010, Pages: 1018–1031, Bing Gong, Fei Chen, Yong Pan, Isabel Arrieta-Cruz, Yukiko Yoshida, Vahram Haroutunian and Giulio M. Pasinetti

    Article first published online : 29 OCT 2010, DOI: 10.1111/j.1474-9726.2010.00632.x

  12. β-Amyloid pathology alters neural network activation during retrieval of contextual fear memories in a mouse model of Alzheimer's disease

    European Journal of Neuroscience

    Volume 39, Issue 10, May 2014, Pages: 1690–1703, Mariah J. Lelos and Mark A. Good

    Article first published online : 16 MAR 2014, DOI: 10.1111/ejn.12527

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    A role for 12/15 lipoxygenase in the amyloid β precursor protein metabolism

    Journal of Neurochemistry

    Volume 103, Issue 1, October 2007, Pages: 380–387, Francesca Succol and Domenico Praticò

    Article first published online : 3 JUN 2007, DOI: 10.1111/j.1471-4159.2007.04742.x

  14. Regulation of Forkhead Transcription Factor FoxO3a Contributes to Calorie Restriction-induced Prevention of Alzheimer's Disease-type Amyloid Neuropathology and Spatial Memory Deterioration

    Annals of the New York Academy of Sciences

    Volume 1147, Issue 1, December 2008, Pages: 335–347, Weiping Qin, Wei Zhao, Lap Ho, Jun Wang, Kenneth Walsh, Sam Gandy and Giulio Maria Pasinetti

    Article first published online : 8 DEC 2008, DOI: 10.1196/annals.1427.024

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    15-Lipoxygenase-1 expression suppresses the invasive properties of colorectal carcinoma cell lines HCT-116 and HT-29

    Cancer Science

    Volume 100, Issue 12, December 2009, Pages: 2283–2291, Ismail Çimen, Seda Tunçay and Sreeparna Banerjee

    Article first published online : 17 AUG 2009, DOI: 10.1111/j.1349-7006.2009.01313.x

  16. 15-lipoxygenase metabolites play an important role in the development of a T-helper type 1 allergic inflammation induced by double-stranded RNA

    Clinical & Experimental Allergy

    Volume 39, Issue 6, June 2009, Pages: 908–917, S. G. Jeon, H.-G. Moon, Y.-S. Kim, J.-P. Choi, T.-S. Shin, S.-W. Hong, Y.-M. Tae, S.-H. Kim, Z. Zhu, Y. S. Gho and Y.-K. Kim

    Article first published online : 25 FEB 2009, DOI: 10.1111/j.1365-2222.2009.03211.x

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    Behavioral stress accelerates plaque pathogenesis in the brain of Tg2576 mice via generation of metabolic oxidative stress

    Journal of Neurochemistry

    Volume 108, Issue 1, January 2009, Pages: 165–175, Kang-Woo Lee, Jung-Bin Kim, Ji-Seon Seo, Tae-Kyung Kim, Joo-Young Im, In-Sun Baek, Kyoung-Shim Kim, Ja-Kyeong Lee and Pyung-Lim Han

    Article first published online : 6 NOV 2008, DOI: 10.1111/j.1471-4159.2008.05769.x

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    Swedish mutant APP suppresses osteoblast differentiation and causes osteoporotic deficit, which are ameliorated by N-acetyl-L-cysteine

    Journal of Bone and Mineral Research

    Volume 28, Issue 10, October 2013, Pages: 2122–2135, Wen-Fang Xia, Ji-Ung Jung, Cui Shun, Shan Xiong, Lei Xiong, Xing-Ming Shi, Lin Mei and Wen-Cheng Xiong

    Article first published online : 18 SEP 2013, DOI: 10.1002/jbmr.1954

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    Hanging in the balance: endogenous anti-inflammatory mechanisms in tissue repair and fibrosis

    The Journal of Pathology

    Volume 229, Issue 2, January 2013, Pages: 250–263, Amiram Ariel and Orly Timor

    Article first published online : 12 DEC 2012, DOI: 10.1002/path.4108

  20. 15-LO/15-HETE Mediated Vascular Adventitia Fibrosis via p38 MAPK-Dependent TGF-β

    Journal of Cellular Physiology

    Volume 229, Issue 2, February 2014, Pages: 245–257, Li Zhang, Yumei Li, Minggang Chen, Xiaojie Su, Dan Yi, Ping Lu and Daling Zhu

    Article first published online : 25 OCT 2013, DOI: 10.1002/jcp.24443