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There are 7371 results for: content related to: What's next for Alzheimer treatment?

  1. You have full text access to this OnlineOpen article
    A critique of the drug discovery and phase 3 clinical programs targeting the amyloid hypothesis for Alzheimer disease

    Annals of Neurology

    Volume 76, Issue 2, August 2014, Pages: 185–205, Eric Karran and John Hardy

    Article first published online : 2 JUL 2014, DOI: 10.1002/ana.24188

  2. You have free access to this content
    Management of peri-operative anti-thrombotic therapy

    Anaesthesia

    Volume 70, Issue s1, January 2015, Pages: 58–e23, J. J. van Veen and M. Makris

    Article first published online : 1 DEC 2014, DOI: 10.1111/anae.12900

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    The therapeutics of Alzheimer's disease: Where we stand and where we are heading

    Annals of Neurology

    Volume 74, Issue 3, September 2013, Pages: 328–336, Dennis J. Selkoe

    Article first published online : 9 OCT 2013, DOI: 10.1002/ana.24001

  4. Cerebrospinal fluid β-amyloid and phospho-tau biomarker interactions affecting brain structure in preclinical Alzheimer disease

    Annals of Neurology

    Volume 76, Issue 2, August 2014, Pages: 223–230, Juan Fortea, Eduard Vilaplana, Daniel Alcolea, María Carmona-Iragui, María-Belén Sánchez-Saudinos, Isabel Sala, Sofía Antón-Aguirre, Sofía González, Santiago Medrano, Jordi Pegueroles, Estrella Morenas, Jordi Clarimón, Rafael Blesa, Alberto Lleó and for the Alzheimer's Disease Neuroimaging Initiative

    Article first published online : 13 JUN 2014, DOI: 10.1002/ana.24186

  5. Brain–computer interface boosts motor imagery practice during stroke recovery

    Annals of Neurology

    Volume 77, Issue 5, May 2015, Pages: 851–865, Floriana Pichiorri, Giovanni Morone, Manuela Petti, Jlenia Toppi, Iolanda Pisotta, Marco Molinari, Stefano Paolucci, Maurizio Inghilleri, Laura Astolfi, Febo Cincotti and Donatella Mattia

    Article first published online : 27 MAR 2015, DOI: 10.1002/ana.24390

  6. β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons

    Annals of Neurology

    Volume 74, Issue 1, July 2013, Pages: 109–118, Grit Taschenberger, Johan Toloe, Julia Tereshchenko, Jasper Akerboom, Pauline Wales, Roland Benz, Stefan Becker, Tiago F. Outeiro, Loren L. Looger, Mathias Bähr, Markus Zweckstetter and Sebastian Kügler

    Article first published online : 6 AUG 2013, DOI: 10.1002/ana.23905

  7. Modulation of amyloid precursor protein expression reduces β-amyloid deposition in a mouse model

    Annals of Neurology

    Volume 75, Issue 5, May 2014, Pages: 684–699, Ayodeji A. Asuni, Maitea Guridi, Joanna E. Pankiewicz, Sandrine Sanchez and Martin J. Sadowski

    Article first published online : 28 APR 2014, DOI: 10.1002/ana.24149

  8. Comparing positron emission tomography imaging and cerebrospinal fluid measurements of β-amyloid

    Annals of Neurology

    Volume 74, Issue 6, December 2013, Pages: 826–836, Susan M. Landau, Ming Lu, Abhinay D. Joshi, Michael Pontecorvo, Mark A. Mintun, John Q. Trojanowski, Leslie M. Shaw, William J. Jagust and for the Alzheimer's Disease Neuroimaging Initiative

    Article first published online : 21 JAN 2014, DOI: 10.1002/ana.23908

  9. Blocking of plasma kallikrein ameliorates stroke by reducing thromboinflammation

    Annals of Neurology

    Volume 77, Issue 5, May 2015, Pages: 784–803, Eva Göb, Stephan Reymann, Friederike Langhauser, Michael K. Schuhmann, Peter Kraft, Ina Thielmann, Kerstin Göbel, Marc Brede, György Homola, László Solymosi, Guido Stoll, Christian Geis, Sven G. Meuth, Bernhard Nieswandt and Christoph Kleinschnitz

    Article first published online : 13 MAR 2015, DOI: 10.1002/ana.24380

  10. Atypical functional brain connectivity during rest in autism spectrum disorders

    Annals of Neurology

    Volume 77, Issue 5, May 2015, Pages: 866–876, Krissy A. R. Doyle-Thomas, Wayne Lee, Nicholas E. V. Foster, Ana Tryfon, Tia Ouimet, Krista L. Hyde, Alan C. Evans, John Lewis, Lonnie Zwaigenbaum, Evdokia Anagnostou and for the NeuroDevNet ASD Imaging Group

    Article first published online : 27 MAR 2015, DOI: 10.1002/ana.24391

  11. Voxel-based morphometric magnetic resonance imaging (MRI) postprocessing in MRI-negative epilepsies

    Annals of Neurology

    Z. Irene Wang, Stephen E. Jones, Zeenat Jaisani, Imad M. Najm, Richard A. Prayson, Richard C. Burgess, Balu Krishnan, Aleksandar Ristic, Chong H. Wong, William Bingaman, Jorge A. Gonzalez-Martinez and Andreas V. Alexopoulos

    Article first published online : 23 APR 2015, DOI: 10.1002/ana.24407

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    Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice

    Annals of Neurology

    Volume 77, Issue 1, January 2015, Pages: 75–99, Oleg Butovsky, Mark P. Jedrychowski, Ron Cialic, Susanne Krasemann, Gopal Murugaiyan, Zain Fanek, David J. Greco, Pauline M. Wu, Camille E. Doykan, Olga Kiner, Robert J. Lawson, Matthew P. Frosch, Nathalie Pochet, Rachid El Fatimy, Anna M. Krichevsky, Steven P. Gygi, Hans Lassmann, James Berry, Merit E. Cudkowicz and Howard L. Weiner

    Article first published online : 27 NOV 2014, DOI: 10.1002/ana.24304

    Corrected by:

    Corrigendum: Corrigendum: Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice

    Article first published online: 22 APR 2015

  13. You have full text access to this OnlineOpen article
    Tau reduction prevents disease in a mouse model of Dravet syndrome

    Annals of Neurology

    Volume 76, Issue 3, September 2014, Pages: 443–456, Ania L. Gheyara, Ravikumar Ponnusamy, Biljana Djukic, Ryan J. Craft, Kaitlyn Ho, Weikun Guo, Mariel M. Finucane, Pascal E. Sanchez and Lennart Mucke

    Article first published online : 13 AUG 2014, DOI: 10.1002/ana.24230

  14. Early netrin-1 expression impairs central nervous system remyelination

    Annals of Neurology

    Volume 76, Issue 2, August 2014, Pages: 252–268, Vanja Tepavčević, Christophe Kerninon, Marie Stéphane Aigrot, Elodie Meppiel, Sabah Mozafari, Raphaelle Arnould-Laurent, Philippe Ravassard, Timothy E. Kennedy, Brahim Nait-Oumesmar and Catherine Lubetzki

    Article first published online : 15 JUL 2014, DOI: 10.1002/ana.24201

  15. Rare variants in γ-aminobutyric acid type A receptor genes in rolandic epilepsy and related syndromes

    Annals of Neurology

    Eva M. Reinthaler, Borislav Dejanovic, Dennis Lal, Marcus Semtner, Yvonne Merkler, Annika Reinhold, Dorothea A. Pittrich, Christoph Hotzy, Martha Feucht, Hannelore Steinböck, Ursula Gruber-Sedlmayr, Gabriel M. Ronen, Birgit Neophytou, Julia Geldner, Edda Haberlandt, Hiltrud Muhle, M. Arfan Ikram, Cornelia M. van Duijn, Andre G. Uitterlinden, Albert Hofman, Janine Altmüller, Amit Kawalia, Mohammad R. Toliat, EuroEPINOMICS Consortium, Peter Nürnberg, Holger Lerche, Michael Nothnagel, Holger Thiele, Thomas Sander, Jochen C. Meier, Günter Schwarz, Bernd A. Neubauer and Fritz Zimprich

    Article first published online : 28 MAR 2015, DOI: 10.1002/ana.24395

  16. You have full text access to this OnlineOpen article
    Mutations in gamma adducin are associated with inherited cerebral palsy

    Annals of Neurology

    Volume 74, Issue 6, December 2013, Pages: 805–814, Michael C. Kruer, Tyler Jepperson, Sudeshna Dutta, Robert D. Steiner, Ellen Cottenie, Lynn Sanford, Mark Merkens, Barry S. Russman, Peter A. Blasco, Guang Fan, Jeffrey Pollock, Sarah Green, Randall L. Woltjer, Catherine Mooney, Doris Kretzschmar, Coro Paisán-Ruiz and Henry Houlden

    Article first published online : 21 JAN 2014, DOI: 10.1002/ana.23971

  17. Normobaric hypoxia and symptoms of acute mountain sickness: Elevated brain volume and intracranial hypertension

    Annals of Neurology

    Volume 75, Issue 6, June 2014, Pages: 890–898, Justin S. Lawley, Noam Alperin, Ahmet M. Bagci, Sang H. Lee, Paul G. Mullins, Samuel J. Oliver and Jamie H. Macdonald

    Article first published online : 20 MAY 2014, DOI: 10.1002/ana.24171

  18. Atypical phenotypes in titinopathies explained by second titin mutations

    Annals of Neurology

    Volume 75, Issue 2, February 2014, Pages: 230–240, Anni Evilä, Anna Vihola, Jaakko Sarparanta, Olayinka Raheem, Johanna Palmio, Satu Sandell, Bruno Eymard, Isabel Illa, Ricard Rojas-Garcia, Karolina Hankiewicz, Luis Negrão, Tuija Löppönen, Pekka Nokelainen, Mikko Kärppä, Sini Penttilä, Mark Screen, Tiina Suominen, Isabelle Richard, Peter Hackman and Bjarne Udd

    Article first published online : 24 FEB 2014, DOI: 10.1002/ana.24102

  19. Effect of sildenafil on skeletal and cardiac muscle in Becker muscular dystrophy

    Annals of Neurology

    Volume 76, Issue 4, October 2014, Pages: 550–557, Nanna Witting, Christina Kruuse, Bo Nyhuus, Kira P. Prahm, Gulsenay Citirak, Stine J. Lundgaard, Sebastian von Huth, Niels Vejlstrup, Ulrich Lindberg, Thomas O. Krag and John Vissing

    Article first published online : 15 JUL 2014, DOI: 10.1002/ana.24216

  20. Leptomeningeal collaterals are associated with modifiable metabolic risk factors

    Annals of Neurology

    Volume 74, Issue 2, August 2013, Pages: 241–248, Bijoy K. Menon, Eric E. Smith, Shelagh B. Coutts, Donald G. Welsh, James E. Faber, Mayank Goyal, Michael D. Hill, Andrew M. Demchuk, Zaheed Damani, Kyung-Hee Cho, Hyuk-Won Chang, Jeong-Ho Hong and Sung Il Sohn

    Article first published online : 4 SEP 2013, DOI: 10.1002/ana.23906