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There are 14881 results for: content related to: Importance and hurdles to drug discovery for neurological disease

  1. α-Synuclein oligomers and clinical implications for Parkinson disease

    Annals of Neurology

    Volume 73, Issue 2, February 2013, Pages: 155–169, Lorraine V. Kalia, Suneil K. Kalia, Pamela J. McLean, Andres M. Lozano and Anthony E. Lang

    Version of Record online : 7 DEC 2012, DOI: 10.1002/ana.23746

  2. Therapeutic prospects for migraine: Can paradise be regained?

    Annals of Neurology

    Volume 74, Issue 3, September 2013, Pages: 423–434, Peter J. Goadsby

    Version of Record online : 9 OCT 2013, DOI: 10.1002/ana.23996

  3. Spinal muscular atrophy: Development and implementation of potential treatments

    Annals of Neurology

    Volume 74, Issue 3, September 2013, Pages: 348–362, W. David Arnold and Arthur H. M. Burghes

    Version of Record online : 9 OCT 2013, DOI: 10.1002/ana.23995

  4. Novel approaches and challenges to treatment of central nervous system viral infections

    Annals of Neurology

    Volume 74, Issue 3, September 2013, Pages: 412–422, Avindra Nath and Kenneth L. Tyler

    Version of Record online : 9 OCT 2013, DOI: 10.1002/ana.23988

  5. Neurorehabilitation: Motor recovery after stroke as an example

    Annals of Neurology

    Volume 74, Issue 3, September 2013, Pages: 373–381, Karunesh Ganguly, Nancy N. Byl and Gary M. Abrams

    Version of Record online : 9 OCT 2013, DOI: 10.1002/ana.23994

  6. You have full text access to this OnlineOpen article
    Timing of deep brain stimulation in Parkinson disease: A need for reappraisal?

    Annals of Neurology

    Volume 73, Issue 5, May 2013, Pages: 565–575, Ruth-Mary deSouza, Elena Moro, Anthony E. Lang and Anthony H. V. Schapira

    Version of Record online : 28 MAY 2013, DOI: 10.1002/ana.23890

  7. Nitric oxide signaling in the brain: A new target for inhaled nitric oxide?

    Annals of Neurology

    Volume 73, Issue 4, April 2013, Pages: 442–448, Christiane Charriaut-Marlangue, Philippe Bonnin, Hoa Pham, Gauthier Loron, Pierre-Louis Leger, Pierre Gressens, Sylvain Renolleau and Olivier Baud

    Version of Record online : 12 MAR 2013, DOI: 10.1002/ana.23842

  8. You have full text access to this OnlineOpen article
    Therapeutic advances in muscular dystrophy

    Annals of Neurology

    Volume 74, Issue 3, September 2013, Pages: 404–411, Doris G. Leung and Kathryn R. Wagner

    Version of Record online : 9 OCT 2013, DOI: 10.1002/ana.23989

  9. Mediterranean diet, stroke, cognitive impairment, and depression: A meta-analysis

    Annals of Neurology

    Volume 74, Issue 4, October 2013, Pages: 580–591, Theodora Psaltopoulou, Theodoros N. Sergentanis, Demosthenes B. Panagiotakos, Ioannis N. Sergentanis, Rena Kosti and Nikolaos Scarmeas

    Version of Record online : 16 SEP 2013, DOI: 10.1002/ana.23944

  10. Stages of pTDP-43 pathology in amyotrophic lateral sclerosis

    Annals of Neurology

    Volume 74, Issue 1, July 2013, Pages: 20–38, Johannes Brettschneider, Kelly Del Tredici, Jon B. Toledo, John L. Robinson, David J. Irwin, Murray Grossman, EunRan Suh, Vivianna M. Van Deerlin, Elisabeth M. Wood, Young Baek, Linda Kwong, Edward B. Lee, Lauren Elman, Leo McCluskey, Lubin Fang, Simone Feldengut, Albert C. Ludolph, Virginia M.-Y. Lee, Heiko Braak and John Q. Trojanowski

    Version of Record online : 19 JUN 2013, DOI: 10.1002/ana.23937

  11. Management of patients with stroke: Is it time to expand treatment options?

    Annals of Neurology

    Volume 74, Issue 1, July 2013, Pages: 4–10, Harold P. Adams Jr and Randolph J. Nudo

    Version of Record online : 6 AUG 2013, DOI: 10.1002/ana.23948

  12. Cholinergic enhancement of functional networks in older adults with mild cognitive impairment

    Annals of Neurology

    Volume 73, Issue 6, June 2013, Pages: 762–773, Judy Pa, Anne S. Berry, Mariana Compagnone, Jacqueline Boccanfuso, Ian Greenhouse, Michael T. Rubens, Julene K. Johnson and Adam Gazzaley

    Version of Record online : 17 JUN 2013, DOI: 10.1002/ana.23874

  13. Animal models and therapeutic prospects for Charcot–Marie–Tooth disease

    Annals of Neurology

    Volume 74, Issue 3, September 2013, Pages: 391–396, Delphine Bouhy and Vincent Timmerman

    Version of Record online : 9 OCT 2013, DOI: 10.1002/ana.23987

  14. Caffeine and adenosine A2A receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado–Joseph disease

    Annals of Neurology

    Volume 73, Issue 5, May 2013, Pages: 655–666, Nélio Gonçalves, Ana T. Simões, Rodrigo A. Cunha and Luís Pereira de Almeida

    Version of Record online : 26 APR 2013, DOI: 10.1002/ana.23866

  15. CaV2.1 ablation in cortical interneurons selectively impairs fast-spiking basket cells and causes generalized seizures

    Annals of Neurology

    Volume 74, Issue 2, August 2013, Pages: 209–222, Elsa Rossignol, Illya Kruglikov, Arn M. J. M. van den Maagdenberg, Bernardo Rudy and Gord Fishell

    Version of Record online : 1 JUL 2013, DOI: 10.1002/ana.23913

  16. Advances and challenges in treatment and prevention of ischemic stroke

    Annals of Neurology

    Volume 74, Issue 3, September 2013, Pages: 363–372, Aaron W. Grossman and Joseph P. Broderick

    Version of Record online : 9 OCT 2013, DOI: 10.1002/ana.23993

  17. The metabolic syndrome and neuropathy: Therapeutic challenges and opportunities

    Annals of Neurology

    Volume 74, Issue 3, September 2013, Pages: 397–403, Brian Callaghan and Eva Feldman

    Version of Record online : 9 OCT 2013, DOI: 10.1002/ana.23986

  18. RNA in blood is altered prior to hemorrhagic transformation in ischemic stroke

    Annals of Neurology

    Volume 74, Issue 2, August 2013, Pages: 232–240, Glen C. Jickling, Bradley P. Ander, Boryana Stamova, Xinhua Zhan, Dazhi Liu, Lena Rothstein, Piero Verro, Jane Khoury, Edward C. Jauch, Arthur M. Pancioli, Joseph P. Broderick and Frank R. Sharp

    Version of Record online : 10 SEP 2013, DOI: 10.1002/ana.23883

  19. You have full text access to this OnlineOpen article
    Carotid plaque hemorrhage on magnetic resonance imaging strongly predicts recurrent ischemia and stroke

    Annals of Neurology

    Volume 73, Issue 6, June 2013, Pages: 774–784, Akram A. Hosseini, Neghal Kandiyil, Shane T. S. MacSweeney, Nishath Altaf and Dorothee P. Auer

    Version of Record online : 4 JUN 2013, DOI: 10.1002/ana.23876

  20. Diminished Th17 (not Th1) responses underlie multiple sclerosis disease abrogation after hematopoietic stem cell transplantation

    Annals of Neurology

    Volume 73, Issue 3, March 2013, Pages: 341–354, Peter J. Darlington, Tarik Touil, Jean-Sebastien Doucet, Denis Gaucher, Joumana Zeidan, Dominique Gauchat, Rachel Corsini, Ho Jin Kim, Martin Duddy, Farzaneh Jalili, Nathalie Arbour, Hania Kebir, Jacqueline Chen, Douglas L. Arnold, Marjorie Bowman, Jack Antel, Alexandre Prat, Mark S. Freedman, Harold Atkins, Rafick Sekaly, Remi Cheynier, Amit Bar-Or and for the Canadian MS/BMT Study Group

    Version of Record online : 5 MAR 2013, DOI: 10.1002/ana.23784