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  1. Seasonal variation of relapse rate in multiple sclerosis is latitude dependent

    Annals of Neurology

    Volume 76, Issue 6, December 2014, Pages: 880–890, Tim Spelman, Orla Gray, Maria Trojano, Thor Petersen, Guillermo Izquierdo, Alessandra Lugaresi, Raymond Hupperts, Roberto Bergamaschi, Pierre Duquette, Pierre Grammond, Giorgio Giuliani, Cavit Boz, Freek Verheul, Celia Oreja-Guevara, Michael Barnett, Francois Grand'Maison, Maria Edite Rio, Jeannette Lechner-Scott, Vincent Van Pesch, Ricardo Fernandez Bolanos, Shlomo Flechter, Leontien Den Braber-Moerland, Gerardo Iuliano, Maria Pia Amato, Mark Slee, Edgardo Cristiano, Maria Laura Saladino, Mark Paine, Norbert Vella, Krisztian Kasa, Norma Deri, Joseph Herbert, Fraser Moore, Tatjana Petkovska-Boskova, Raed Alroughani, Aldo Savino, Cameron Shaw, Steve Vucic, Vetere Santiago, Elizabeth Alejandra Bacile, Eli Skromne, Dieter Poehlau, Jose Antonio Cabrera-Gomez, Robyn Lucas and Helmut Butzkueven

    Article first published online : 20 OCT 2014, DOI: 10.1002/ana.24287

  2. You have full text access to this OnlineOpen article
    Metallothioneins as dynamic markers for brain disease in lysosomal disorders

    Annals of Neurology

    Volume 75, Issue 1, January 2014, Pages: 127–137, Martina Cesani, Eleonora Cavalca, Romina Macco, Giuseppe Leoncini, Maria Rosa Terreni, Laura Lorioli, Roberto Furlan, Giancarlo Comi, Claudio Doglioni, Daniele Zacchetti, Maria Sessa, Clemens R. Scherzer and Alessandra Biffi

    Article first published online : 12 FEB 2014, DOI: 10.1002/ana.24053

  3. C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: A genome-wide meta-analysis

    Annals of Neurology

    Volume 76, Issue 1, July 2014, Pages: 120–133, Frank P. Diekstra, Vivianna M. Van Deerlin, John C. van Swieten, Ammar Al-Chalabi, Albert C. Ludolph, Jochen H. Weishaupt, Orla Hardiman, John E. Landers, Robert H. Brown Jr, Michael A. van Es, R. Jeroen Pasterkamp, Max Koppers, Peter M. Andersen, Karol Estrada, Fernando Rivadeneira, Albert Hofman, André G. Uitterlinden, Philip van Damme, Judith Melki, Vincent Meininger, Aleksey Shatunov, Christopher E. Shaw, P. Nigel Leigh, Pamela J. Shaw, Karen E. Morrison, Isabella Fogh, Adriano Chiò, Bryan J. Traynor, David Czell, Markus Weber, Peter Heutink, Paul I. W. de Bakker, Vincenzo Silani, Wim Robberecht, Leonard H. van den Berg and Jan H. Veldink

    Article first published online : 27 JUN 2014, DOI: 10.1002/ana.24198

  4. Copy number variation plays an important role in clinical epilepsy

    Annals of Neurology

    Volume 75, Issue 6, June 2014, Pages: 943–958, Heather Olson, Yiping Shen, Jennifer Avallone, Beth R. Sheidley, Rebecca Pinsky, Ann M. Bergin, Gerard T. Berry, Frank H. Duffy, Yaman Eksioglu, David J. Harris, Fuki M. Hisama, Eugenia Ho, Mira Irons, Christina M. Jacobsen, Philip James, Sanjeev Kothare, Omar Khwaja, Jonathan Lipton, Tobias Loddenkemper, Jennifer Markowitz, Kiran Maski, J. Thomas Megerian, Edward Neilan, Peter C. Raffalli, Michael Robbins, Amy Roberts, Eugene Roe, Caitlin Rollins, Mustafa Sahin, Dean Sarco, Alison Schonwald, Sharon E. Smith, Janet Soul, Joan M. Stoler, Masanori Takeoka, Wen-Han Tan, Alcy R. Torres, Peter Tsai, David K. Urion, Laura Weissman, Robert Wolff, Bai-Lin Wu, David T. Miller and Annapurna Poduri

    Article first published online : 13 JUN 2014, DOI: 10.1002/ana.24178

  5. Genetic association signal near NTN4 in Tourette syndrome

    Annals of Neurology

    Volume 76, Issue 2, August 2014, Pages: 310–315, Peristera Paschou, Dongmei Yu, Gloria Gerber, Patrick Evans, Fotis Tsetsos, Lea K. Davis, Iordanis Karagiannidis, Jonathan Chaponis, Eric Gamazon, Kirsten Mueller-Vahl, Manfred Stuhrmann, Monika Schloegelhofer, Mara Stamenkovic, Johannes Hebebrand, Markus Noethen, Peter Nagy, Csaba Barta, Zsanett Tarnok, Renata Rizzo, Christel Depienne, Yulia Worbe, Andreas Hartmann, Danielle C. Cath, Cathy L. Budman, Paul Sandor, Cathy Barr, Thomas Wolanczyk, Harvey Singer, I-Ching Chou, Marco Grados, Danielle Posthuma, Guy A. Rouleau, Harald Aschauer, Nelson B. Freimer, David L. Pauls, Nancy J. Cox, Carol A. Mathews and Jeremiah M. Scharf

    Article first published online : 21 JUL 2014, DOI: 10.1002/ana.24215

  6. You have full text access to this OnlineOpen article
    Genetics of low spinal muscular atrophy carrier frequency in sub-Saharan Africa

    Annals of Neurology

    Volume 75, Issue 4, April 2014, Pages: 525–532, Modibo Sangaré, Brant Hendrickson, Hammadoun Ali Sango, Kelian Chen, Jonathan Nofziger, Abdelbasset Amara, Amalia Dutra, Alice B. Schindler, Aldiouma Guindo, Mahamadou Traoré, George Harmison, Evgenia Pak, Fatoumata N'Go Yaro, Katherine Bricceno, Christopher Grunseich, Guibin Chen, Manfred Boehm, Kristen Zukosky, Nouhoum Bocoum, Katherine G. Meilleur, Fatoumata Daou, Koumba Bagayogo, Yaya Ibrahim Coulibaly, Mahamadou Diakité, Michael P. Fay, Hee-Suk Lee, Ali Saad, Moez Gribaa, Andrew B. Singleton, Youssoufa Maiga, Sungyoung Auh, Guida Landouré, Rick M. Fairhurst, Barrington G. Burnett, Thomas Scholl and Kenneth H. Fischbeck

    Article first published online : 2 APR 2014, DOI: 10.1002/ana.24114

  7. PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation

    Annals of Neurology

    Volume 76, Issue 3, September 2014, Pages: 379–392, Gyungah Jun, Hirohide Asai, Ella Zeldich, Elodie Drapeau, CiDi Chen, Jaeyoon Chung, Jong-Ho Park, Sehwa Kim, Vahram Haroutunian, Tatiana Foroud, Ryozo Kuwano, Jonathan L. Haines, Margaret A. Pericak-Vance, Gerard D. Schellenberg, Kathryn L. Lunetta, Jong-Won Kim, Joseph D. Buxbaum, Richard Mayeux, Tsuneya Ikezu, Carmela R. Abraham and Lindsay A. Farrer

    Article first published online : 29 JUL 2014, DOI: 10.1002/ana.24219

  8. Overlapping demyelinating syndromes and anti–N-methyl-D-aspartate receptor encephalitis

    Annals of Neurology

    Volume 75, Issue 3, March 2014, Pages: 411–428, Maarten J. Titulaer, Romana Höftberger, Takahiro Iizuka, Frank Leypoldt, Lindsey McCracken, Tania Cellucci, Leslie A. Benson, Huidy Shu, Takashi Irioka, Makito Hirano, Gagandeep Singh, Alvaro Cobo Calvo, Kenichi Kaida, Pamela S. Morales, Paul W. Wirtz, Tomotaka Yamamoto, Markus Reindl, Myrna R. Rosenfeld, Francesc Graus, Albert Saiz and Josep Dalmau

    Article first published online : 13 MAR 2014, DOI: 10.1002/ana.24117

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    Cerebrospinal fluid neurofilament concentration reflects disease severity in frontotemporal degeneration

    Annals of Neurology

    Volume 75, Issue 1, January 2014, Pages: 116–126, Carole S. Scherling, Tracey Hall, Flora Berisha, Kristen Klepac, Anna Karydas, Giovanni Coppola, Joel H. Kramer, Gil Rabinovici, Michael Ahlijanian, Bruce L. Miller, William Seeley, Lea T. Grinberg, Howard Rosen, Jere Meredith Jr and Adam L. Boxer

    Article first published online : 2 JAN 2014, DOI: 10.1002/ana.24052

  10. Cerebrospinal fluid JC virus antibody index for diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy

    Annals of Neurology

    Volume 76, Issue 6, December 2014, Pages: 792–801, Clemens Warnke, Gloria von Geldern, Philipp Markwerth, Thomas Dehmel, Robert Hoepner, Ralf Gold, Michael Pawlita, Tania Kümpfel, Mathias Mäurer, Martin Stangel, Florian Wegner, Reinhard Hohlfeld, Vera Straeten, Volker Limmroth, Thomas Weber, Derik Hermsen, Christoph Kleinschnitz, Hans-Peter Hartung, Mike P. Wattjes, Anders Svenningson, Eugene Major, Tomas Olsson, Bernd C. Kieseier and Ortwin Adams

    Article first published online : 8 MAY 2014, DOI: 10.1002/ana.24153

  11. You have full text access to this OnlineOpen article
    GRIN2B mutations in west syndrome and intellectual disability with focal epilepsy

    Annals of Neurology

    Volume 75, Issue 1, January 2014, Pages: 147–154, Johannes R. Lemke, Rik Hendrickx, Kirsten Geider, Bodo Laube, Michael Schwake, Robert J. Harvey, Victoria M. James, Alex Pepler, Isabelle Steiner, Konstanze Hörtnagel, John Neidhardt, Susanne Ruf, Markus Wolff, Deborah Bartholdi, Roberto Caraballo, Konrad Platzer, Arvid Suls, Peter De Jonghe, Saskia Biskup and Sarah Weckhuysen

    Article first published online : 2 JAN 2014, DOI: 10.1002/ana.24073

  12. Immunoglobulin M oligoclonal bands: Biomarker of targetable inflammation in primary progressive multiple sclerosis

    Annals of Neurology

    Volume 76, Issue 2, August 2014, Pages: 231–240, Luisa M. Villar, Bonaventura Casanova, Nadia Ouamara, Manuel Comabella, Farzaneh Jalili, David Leppert, Clara de Andrés, Guillermo Izquierdo, Rafael Arroyo, Timuçin Avşar, Sergey V. Lapin, Trina Johnson, Xavier Montalbán, Oscar Fernández, Roberto Álvarez-Lafuente, Donna Masterman, María I. García-Sánchez, Francisco Coret, Aksel Siva, Evgeniy Evdoshenko, José C. Álvarez-Cermeño and Amit Bar-Or

    Article first published online : 2 JUL 2014, DOI: 10.1002/ana.24190

  13. You have full text access to this OnlineOpen article
    Predicting Alzheimer disease with β-amyloid imaging: Results from the Australian imaging, biomarkers, and lifestyle study of ageing

    Annals of Neurology

    Volume 74, Issue 6, December 2013, Pages: 905–913, Christopher C. Rowe, Pierrick Bourgeat, Kathryn A. Ellis, Belinda Brown, Yen Ying Lim, Rachel Mulligan, Gareth Jones, Paul Maruff, Michael Woodward, Roger Price, Peter Robins, Henri Tochon-Danguy, Graeme O'Keefe, Kerryn E. Pike, Paul Yates, Cassandra Szoeke, Olivier Salvado, S. Lance Macaulay, Timothy O'Meara, Richard Head, Lynne Cobiac, Greg Savage, Ralph Martins, Colin L. Masters, David Ames and Victor L. Villemagne

    Article first published online : 21 JAN 2014, DOI: 10.1002/ana.24040

  14. Absent CNKSR2 causes seizures and intellectual, attention, and language deficits

    Annals of Neurology

    Volume 76, Issue 5, November 2014, Pages: 758–764, Andrea K. Vaags, Sarah Bowdin, Mary-Lou Smith, Brigitte Gilbert-Dussardier, Katja S. Brocke-Holmefjord, Katia Sinopoli, Cindy Gilles, Tove B. Haaland, Catherine Vincent-Delorme, Emmanuelle Lagrue, Radu Harbuz, Susan Walker, Christian R. Marshall, Gunnar Houge, Vera M. Kalscheuer, Stephen W. Scherer and Berge A. Minassian

    Article first published online : 4 OCT 2014, DOI: 10.1002/ana.24274

  15. Hippocampal sclerosis after febrile status epilepticus: The FEBSTAT study

    Annals of Neurology

    Volume 75, Issue 2, February 2014, Pages: 178–185, Darrell V. Lewis, Shlomo Shinnar, Dale C. Hesdorffer, Emilia Bagiella, Jacqueline A. Bello, Stephen Chan, Yuan Xu, James MacFall, William A. Gomes, Solomon L. Moshé, Gary W. Mathern, John M. Pellock, Douglas R. Nordli Jr, L. Matthew Frank, James Provenzale, Ruth C. Shinnar, Leon G. Epstein, David Masur, Claire Litherland, Shumei Sun and the FEBSTAT Study Team

    Article first published online : 1 MAR 2014, DOI: 10.1002/ana.24081

  16. Epigenetic therapy for Friedreich ataxia

    Annals of Neurology

    Volume 76, Issue 4, October 2014, Pages: 489–508, Elisabetta Soragni, Wenyan Miao, Marco Iudicello, David Jacoby, Stefania De Mercanti, Marinella Clerico, Filomena Longo, Antonio Piga, Sherman Ku, Erica Campau, Jintang Du, Pablo Penalver, Myriam Rai, Joseph C. Madara, Kristopher Nazor, Melinda O'Connor, Anton Maximov, Jeanne F. Loring, Massimo Pandolfo, Luca Durelli, Joel M. Gottesfeld and James R. Rusche

    Article first published online : 16 SEP 2014, DOI: 10.1002/ana.24260

  17. Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization

    Annals of Neurology

    Judith Eschbach, Björn von Einem, Kathrin Müller, Hanna Bayer, Annika Scheffold, Bradley E. Morrison, K. Lenhard Rudolph, Dietmar R. Thal, Anke Witting, Patrick Weydt, Markus Otto, Michael Fauler, Birgit Liss, Pamela J. McLean, Albert R. La Spada, Albert C. Ludolph, Jochen H. Weishaupt and Karin M. Danzer

    Article first published online : 19 DEC 2014, DOI: 10.1002/ana.24294

  18. Sequencing of Charcot–Marie–Tooth disease genes in a toxic polyneuropathy

    Annals of Neurology

    Volume 76, Issue 5, November 2014, Pages: 727–737, Andreas S. Beutler, Amit A. Kulkarni, Rahul Kanwar, Christopher J. Klein, Terry M. Therneau, Rui Qin, Michaela S. Banck, Ganesh K. Boora, Kathryn J. Ruddy, Yanhong Wu, Regenia L. Smalley, Julie M. Cunningham, Nguyet Anh Le-Lindqwister, Peter Beyerlein, Gary P. Schroth, Anthony J. Windebank, Stephan Züchner and Charles L. Loprinzi

    Article first published online : 17 SEP 2014, DOI: 10.1002/ana.24265

  19. Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice

    Annals of Neurology

    Oleg Butovsky, Mark P. Jedrychowski, Ron Cialic, Susanne Krasemann, Gopal Murugaiyan, Zain Fanek, David J. Greco, Pauline M. Wu, Camille E. Doykan, Olga Kiner, Robert J. Lawson, Matthew P. Frosch, Nathalie Pochet, Rachid El Fatimy, Anna M. Krichevsky, Steven P. Gygi, Hans Lassmann, James Berry, Merit E. Cudkowicz and Howard L. Weiner

    Article first published online : 27 NOV 2014, DOI: 10.1002/ana.24304

  20. DEPDC5 mutations in genetic focal epilepsies of childhood

    Annals of Neurology

    Volume 75, Issue 5, May 2014, Pages: 788–792, Dennis Lal, Eva M. Reinthaler, Julian Schubert, Hiltrud Muhle, Erik Riesch, Gerhard Kluger, Kamel Jabbari, Amit Kawalia, Christine Bäumel, Hans Holthausen, Andreas Hahn, Martha Feucht, Birgit Neophytou, Edda Haberlandt, Felicitas Becker, Janine Altmüller, Holger Thiele, Johannes R. Lemke, Holger Lerche, Peter Nürnberg, Thomas Sander, Yvonne Weber, Fritz Zimprich and Bernd A. Neubauer

    Article first published online : 14 APR 2014, DOI: 10.1002/ana.24127