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There are 75730 results for: content related to: Probing the Conformational Diversity of Cancer-Associated Mutations in p53 with Ion-Mobility Mass Spectrometry

  1. Probing the Conformational Diversity of Cancer-Associated Mutations in p53 with Ion-Mobility Mass Spectrometry

    Angewandte Chemie International Edition

    Volume 52, Issue 16, April 15, 2013, Pages: 4370–4374, Ewa Jurneczko, Faye Cruickshank, Dr. Massimiliano Porrini, Dr. David J. Clarke, Dr. Iain D. G. Campuzano, Dr. Michael Morris, Dr. Penka V. Nikolova and Dr. Perdita E. Barran

    Article first published online : 14 MAR 2013, DOI: 10.1002/anie.201210015

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    TP53 Mutants in the Tower of Babel of Cancer Progression

    Human Mutation

    Volume 35, Issue 6, June 2014, Pages: 689–701, Alessandra Bisio, Yari Ciribilli, Gilberto Fronza, Alberto Inga and Paola Monti

    Article first published online : 14 MAR 2014, DOI: 10.1002/humu.22514

  3. Mutant p53 expression in fallopian tube epithelium drives cell migration

    International Journal of Cancer

    Volume 137, Issue 7, 1 October 2015, Pages: 1528–1538, Suzanne M. Quartuccio, Subbulakshmi Karthikeyan, Sharon L. Eddie, Daniel D. Lantvit, Eoghainín Ó hAinmhire, Dimple A. Modi, Jian-Jun Wei and Joanna E. Burdette

    Article first published online : 11 APR 2015, DOI: 10.1002/ijc.29528

  4. Mutants TP53 p.R273H and p.R273C but not p.R273G Enhance Cancer Cell Malignancy

    Human Mutation

    Volume 35, Issue 5, May 2014, Pages: 575–584, Jie Li, Lixin Yang, Shikha Gaur, Keqiang Zhang, Xiwei Wu, Yate-Ching Yuan, Hongzhi Li, Shuya Hu, Yaguang Weng and Yun Yen

    Article first published online : 7 APR 2014, DOI: 10.1002/humu.22528

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    VRK1 interacts with p53 forming a basal complex that is activated by UV-induced DNA damage

    FEBS Letters

    Volume 588, Issue 5, March 03, 2014, Pages: 692–700, Inmaculada López-Sánchez, Alberto Valbuena, Marta Vázquez-Cedeira, Jyoti Khadake, Marta Sanz-García, Alejandro Carrillo-Jiménez and Pedro A. Lazo

    Article first published online : 31 JAN 2014, DOI: 10.1016/j.febslet.2014.01.040

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    Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer

    EMBO Molecular Medicine

    Volume 5, Issue 5, May 2013, Pages: 707–722, Maura Sonego, Monica Schiappacassi, Sara Lovisa, Alessandra Dall'Acqua, Marina Bagnoli, Francesca Lovat, Massimo Libra, Sara D'Andrea, Vincenzo Canzonieri, Loredana Militello, Marco Napoli, Giorgio Giorda, Barbara Pivetta, Delia Mezzanzanica, Mattia Barbareschi, Barbara Valeri, Silvana Canevari, Alfonso Colombatti, Barbara Belletti, Giannino Del Sal and Gustavo Baldassarre

    Article first published online : 22 APR 2013, DOI: 10.1002/emmm.201201504

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    The A2A adenosine receptor rescues neuritogenesis impaired by p53 blockage via KIF2A, a kinesin family member

    Developmental Neurobiology

    Volume 70, Issue 8, July 2010, Pages: 604–621, Chung-Nan Sun, Hsiu-Chun Chuang, Jiz-Yuh Wang, Si-Ying Chen, Ya-Yun Cheng, Chien-Fei Lee and Yijuang Chern

    Article first published online : 3 MAY 2010, DOI: 10.1002/dneu.20802

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    A split-ubiquitin-based assay detects the influence of mutations on the conformational stability of the p53 DNA binding domain in vivo

    FEBS Letters

    Volume 531, Issue 2, November 06, 2002, Pages: 259–264, Nils Johnsson

    Article first published online : 29 OCT 2002, DOI: 10.1016/S0014-5793(02)03533-0

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    Translational approaches targeting the p53 pathway for anti-cancer therapy

    British Journal of Pharmacology

    Volume 165, Issue 2, January 2012, Pages: 328–344, Frank Essmann and Klaus Schulze-Osthoff

    Article first published online : 16 DEC 2011, DOI: 10.1111/j.1476-5381.2011.01570.x

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    Insights into Wild-Type and Mutant p53 Functions Provided by Genetically Engineered Mice

    Human Mutation

    Volume 35, Issue 6, June 2014, Pages: 715–727, Lawrence A. Donehower

    Article first published online : 5 FEB 2014, DOI: 10.1002/humu.22507

  11. The p53 gene and its role in human brain tumors


    Volume 15, Issue 3, November 1995, Pages: 308–327, Dr. Oliver Bögler, H.-J. Su Huang, Paul Kleihues and Webster K. Cavenee

    Article first published online : 12 OCT 2004, DOI: 10.1002/glia.440150311

  12. Paclitaxel enhanced radiation sensitization for the suppression of human prostate cancer tumor growth via a p53 independent pathway

    The Prostate

    Volume 67, Issue 15, 1 November 2007, Pages: 1630–1640, An Ling Zhang, Pamela J. Russell, Tony Knittel and Chris Milross

    Article first published online : 6 SEP 2007, DOI: 10.1002/pros.20638

  13. Cancer Therapy by Reactivation of the p53 Apoptosis Pathway

    Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts

    Helene Stridh, Vladimir J. N. Bykov, Galina Selivanova, Klas G. Wiman, Pages: 891–912, 2008

    Published Online : 26 MAY 2008, DOI: 10.1002/9783527619665.ch35

  14. Profiling of gene expression changes caused by p53 gain-of-function mutant alleles in prostate cancer cells

    The Prostate

    Volume 65, Issue 4, 1 December 2005, Pages: 375–389, Clifford G. Tepper, Jeffrey P. Gregg, Xu-Bao Shi, Ruth L. Vinall, Colin A. Baron, Philip E. Ryan, Pierre-Yves Desprez, Hsing-Jien Kung and Ralph W. deVere White

    Article first published online : 22 JUL 2005, DOI: 10.1002/pros.20308

  15. Elevated levels of prostate-specific antigen (PSA) in prostate cancer cells expressing mutant p53 is associated with tumor metastasis

    Molecular Carcinogenesis

    Volume 38, Issue 3, November 2003, Pages: 130–140, Sean Downing, Clare Bumak, Sheri Nixdorf, Kim Ow, Pamela Russell and Paul Jackson

    Article first published online : 23 OCT 2003, DOI: 10.1002/mc.10154

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    The role of mutant p53 in human cancer

    The Journal of Pathology

    Volume 223, Issue 2, January 2011, Pages: 116–126, Amanda M Goh, Cynthia R Coffill and David P Lane

    Article first published online : 25 OCT 2010, DOI: 10.1002/path.2784

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    Pharmacological reactivation of p53 as a strategy to treat cancer

    Journal of Internal Medicine

    Volume 277, Issue 2, February 2015, Pages: 248–259, J. Zawacka-Pankau and G. Selivanova

    Article first published online : 26 JAN 2015, DOI: 10.1111/joim.12336

  18. Ranking the Binding Energies of p53 Mutant Activators and Their ADMET Properties

    Chemical Biology & Drug Design

    Volume 86, Issue 2, August 2015, Pages: 163–172, Sara Ibrahim Omar and Jack Tuszynski

    Article first published online : 11 DEC 2014, DOI: 10.1111/cbdd.12480

  19. Gambogic acid-induced degradation of mutant p53 is mediated by proteasome and related to CHIP

    Journal of Cellular Biochemistry

    Volume 112, Issue 2, February 2011, Pages: 509–519, Jia Wang, Qing Zhao, Qi Qi, Hong-yan Gu, Jing-jing Rong, Rong Mu, Mei-juan Zou, Lei Tao, Qi-dong You and Qing-long Guo

    Article first published online : 25 JAN 2011, DOI: 10.1002/jcb.22941

  20. Screening the p53 status of human cell lines using a yeast functional assay

    Molecular Carcinogenesis

    Volume 19, Issue 4, August 1997, Pages: 243–253, Li-Qun Jia, Motonobu Osada, Chikashi Ishioka, Makio Gamo, Shuntaro Ikawa, Takao Suzuki, Hideki Shimodaira, Tomohito Niitani, Toshio Kudo, Mitoshi Akiyama, Narimiti Kimura, Mitsuyoshi Matsuo, Hiroshi Mizusawa, Noriho Tanaka, Hideki Koyama, Masayoshi Namba, Ryunosuke Kanamaru and Toshio Kuroki

    Article first published online : 7 DEC 1998, DOI: 10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D