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There are 15169 results for: content related to: Laboratory Evolution of Stereoselective Enzymes: A Prolific Source of Catalysts for Asymmetric Reactions

  1. A Method for Rapid Directed Evolution

    Protein Engineering Handbook, Volume 1 & Volume 2

    Stefan Lutz, Uwe T. Bornscheuer, Pages: 409–439, 2011

    Published Online : 9 MAR 2011, DOI: 10.1002/9783527634026.ch16

  2. Many Pathways in Laboratory Evolution Can Lead to Improved Enzymes: How to Escape from Local Minima

    ChemBioChem

    Volume 13, Issue 7, May 7, 2012, Pages: 1060–1066, Dr. Yosephine Gumulya, Dr. Joaquin Sanchis and Prof. Dr. Manfred T. Reetz

    Article first published online : 20 APR 2012, DOI: 10.1002/cbic.201100784

  3. Directed Evolution of an Enantioselective Enoate-Reductase: Testing the Utility of Iterative Saturation Mutagenesis

    Advanced Synthesis & Catalysis

    Volume 351, Issue 18, December 2009, Pages: 3287–3305, Despina J. Bougioukou, Sabrina Kille, Andreas Taglieber and Manfred T. Reetz

    Article first published online : 10 DEC 2009, DOI: 10.1002/adsc.200900644

  4. Directed Evolution by Using Iterative Saturation Mutagenesis Based on Multiresidue Sites

    ChemBioChem

    Volume 14, Issue 17, November 25, 2013, Pages: 2301–2309, Dr. Loreto P. Parra, Dr. Rubén Agudo and Prof. Dr. Manfred T. Reetz

    Article first published online : 18 OCT 2013, DOI: 10.1002/cbic.201300486

  5. Enzymes, Directed Evolution

    Standard Article

    Encyclopedia of Industrial Biotechnology

    Manfred T. Reetz

    Published Online : 15 DEC 2009, DOI: 10.1002/9780470054581.eib289

  6. Directed evolution of phenylacetone monooxygenase as an active catalyst for the baeyer–villiger conversion of cyclohexanone to caprolactone

    Biotechnology and Bioengineering

    Volume 112, Issue 7, July 2015, Pages: 1354–1364, Loreto P. Parra, Juan P. Acevedo and Manfred T. Reetz

    Article first published online : 30 APR 2015, DOI: 10.1002/bit.25564

  7. Enhancing the Thermal Robustness of an Enzyme by Directed Evolution: Least Favorable Starting Points and Inferior Mutants Can Map Superior Evolutionary Pathways

    ChemBioChem

    Volume 12, Issue 16, November 4, 2011, Pages: 2502–2510, Dr. Yosephine Gumulya and Prof. Dr. Manfred T. Reetz

    Article first published online : 13 SEP 2011, DOI: 10.1002/cbic.201100412

  8. Achieving Regio- and Enantioselectivity of P450-Catalyzed Oxidative CH Activation of Small Functionalized Molecules by Structure-Guided Directed Evolution

    ChemBioChem

    Volume 13, Issue 10, July 9, 2012, Pages: 1465–1473, Dr. Rubén Agudo, Dr. Gheorghe-Doru Roiban and Prof. Dr. Manfred T. Reetz

    Article first published online : 18 JUN 2012, DOI: 10.1002/cbic.201200244

  9. Directed Evolution of Artificial Metalloenzymes

    Israel Journal of Chemistry

    Volume 55, Issue 1, January 2015, Pages: 51–60, Adriana Ilie and Manfred T. Reetz

    Article first published online : 26 SEP 2014, DOI: 10.1002/ijch.201400087

  10. Protein Engineering of Stereoselective Baeyer–Villiger Monooxygenases

    Chemistry - A European Journal

    Volume 18, Issue 33, August 13, 2012, Pages: 10160–10172, Dr. Zhi-Gang Zhang, Dr. Loreto P. Parra and Prof. Dr. Manfred T. Reetz

    Article first published online : 16 JUL 2012, DOI: 10.1002/chem.201202163

  11. Addressing the Numbers Problem in Directed Evolution

    ChemBioChem

    Volume 9, Issue 11, July 21, 2008, Pages: 1797–1804, Manfred T. Reetz, Daniel Kahakeaw and Renate Lohmer

    Article first published online : 20 JUN 2008, DOI: 10.1002/cbic.200800298

  12. Directed Evolution of Industrial Biocatalysts

    Industrial Biotechnology: Sustainable Growth and Economic Success

    Marlen Schmidt, Dominique Böttcher, Uwe T. Bornscheuer, Pages: 173–205, 2010

    Published Online : 29 APR 2010, DOI: 10.1002/9783527630233.ch4

  13. The Importance of Additive and Non-Additive Mutational Effects in Protein Engineering

    Angewandte Chemie International Edition

    Volume 52, Issue 10, March 4, 2013, Pages: 2658–2666, Prof. Dr. Manfred T. Reetz

    Article first published online : 4 FEB 2013, DOI: 10.1002/anie.201207842

  14. Mutations in Distant Residues Moderately Increase the Enantioselectivity of Pseudomonas fluorescens Esterase towards Methyl 3Bromo-2-methylpropanoate and Ethyl 3Phenylbutyrate

    Chemistry - A European Journal

    Volume 9, Issue 9, May 9, 2003, Pages: 1933–1939, Geoff P. Horsman, Andrew M. F. Liu, Erik Henke, Uwe T. Bornscheuer and Romas J. Kazlauskas

    Article first published online : 9 APR 2003, DOI: 10.1002/chem.200204551

  15. Manipulating the Expression Rate and Enantioselectivity of an Epoxide Hydrolase by Using Directed Evolution

    ChemBioChem

    Volume 12, Issue 10, July 4, 2011, Pages: 1529–1535, Prof. Dr. Manfred T. Reetz and Dr. Huabao Zheng

    Article first published online : 12 MAY 2011, DOI: 10.1002/cbic.201100078

  16. Knowledge-guided laboratory evolution of protein thermolability

    Biotechnology and Bioengineering

    Volume 102, Issue 6, 15 April 2009, Pages: 1712–1717, Manfred T. Reetz, Pankaj Soni and Layla Fernández

    Article first published online : 11 NOV 2008, DOI: 10.1002/bit.22202

  17. Microbes and Enzymes: Recent Trends and New Directions to Expand Protein Space

    Protein Engineering Handbook, Volume 1 & Volume 2

    Ana Beloqui, Miren Zumárraga, Miguel Alcalde, Peter N. Golyshin, Manuel Ferrer, Pages: 233–269, 2011

    Published Online : 9 MAR 2011, DOI: 10.1002/9783527634026.ch9

  18. Enhancing the Efficiency of Directed Evolution in Focused Enzyme Libraries by the Adaptive Substituent Reordering Algorithm

    Chemistry - A European Journal

    Volume 18, Issue 18, April 27, 2012, Pages: 5646–5654, Dr. Xiaojiang Feng, Dr. Joaquin Sanchis, Dr. Manfred T. Reetz and Dr. Herschel Rabitz

    Article first published online : 20 MAR 2012, DOI: 10.1002/chem.201103811

  19. Directed Enzyme and Pathway Evolution

    Enzyme Technologies: Metagenomics, Evolution, Biocatalysis, and Biosynthesis

    Jacob Vick, Claudia Schmidt-Dannert, Pages: 41–75, 2011

    Published Online : 25 MAY 2011, DOI: 10.1002/9780470627303.ch2

  20. Expanding the metabolic engineering toolbox with directed evolution

    Biotechnology Journal

    Volume 8, Issue 12, December 2013, Pages: 1397–1410, Joseph Abatemarco, Andrew Hill and Prof. Hal S. Alper

    Article first published online : 15 JUL 2013, DOI: 10.1002/biot.201300021