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There are 161089 results for: content related to: Laboratory Evolution of Stereoselective Enzymes: A Prolific Source of Catalysts for Asymmetric Reactions

  1. A Method for Rapid Directed Evolution

    Protein Engineering Handbook, Volume 1 & Volume 2

    Stefan Lutz, Uwe T. Bornscheuer, Pages: 409–439, 2011

    Published Online : 9 MAR 2011, DOI: 10.1002/9783527634026.ch16

  2. Directed Evolution of an Enantioselective Enoate-Reductase: Testing the Utility of Iterative Saturation Mutagenesis

    Advanced Synthesis & Catalysis

    Volume 351, Issue 18, December 2009, Pages: 3287–3305, Despina J. Bougioukou, Sabrina Kille, Andreas Taglieber and Manfred T. Reetz

    Article first published online : 10 DEC 2009, DOI: 10.1002/adsc.200900644

  3. Many Pathways in Laboratory Evolution Can Lead to Improved Enzymes: How to Escape from Local Minima

    ChemBioChem

    Volume 13, Issue 7, May 7, 2012, Pages: 1060–1066, Dr. Yosephine Gumulya, Dr. Joaquin Sanchis and Prof. Dr. Manfred T. Reetz

    Article first published online : 20 APR 2012, DOI: 10.1002/cbic.201100784

  4. Enzymes, Directed Evolution

    Standard Article

    Encyclopedia of Industrial Biotechnology

    Manfred T. Reetz

    Published Online : 15 DEC 2009, DOI: 10.1002/9780470054581.eib289

  5. Addressing the Numbers Problem in Directed Evolution

    ChemBioChem

    Volume 9, Issue 11, July 21, 2008, Pages: 1797–1804, Manfred T. Reetz, Daniel Kahakeaw and Renate Lohmer

    Article first published online : 20 JUN 2008, DOI: 10.1002/cbic.200800298

  6. Enhancing the Thermal Robustness of an Enzyme by Directed Evolution: Least Favorable Starting Points and Inferior Mutants Can Map Superior Evolutionary Pathways

    ChemBioChem

    Volume 12, Issue 16, November 4, 2011, Pages: 2502–2510, Dr. Yosephine Gumulya and Prof. Dr. Manfred T. Reetz

    Article first published online : 13 SEP 2011, DOI: 10.1002/cbic.201100412

  7. Achieving Regio- and Enantioselectivity of P450-Catalyzed Oxidative CH Activation of Small Functionalized Molecules by Structure-Guided Directed Evolution

    ChemBioChem

    Volume 13, Issue 10, July 9, 2012, Pages: 1465–1473, Dr. Rubén Agudo, Dr. Gheorghe-Doru Roiban and Prof. Dr. Manfred T. Reetz

    Article first published online : 18 JUN 2012, DOI: 10.1002/cbic.201200244

  8. Manipulating the Expression Rate and Enantioselectivity of an Epoxide Hydrolase by Using Directed Evolution

    ChemBioChem

    Volume 12, Issue 10, July 4, 2011, Pages: 1529–1535, Prof. Dr. Manfred T. Reetz and Dr. Huabao Zheng

    Article first published online : 12 MAY 2011, DOI: 10.1002/cbic.201100078

  9. Directed Evolution of Artificial Metalloenzymes

    Israel Journal of Chemistry

    Volume 55, Issue 1, January 2015, Pages: 51–60, Adriana Ilie and Manfred T. Reetz

    Article first published online : 26 SEP 2014, DOI: 10.1002/ijch.201400087

  10. Directed Evolution by Using Iterative Saturation Mutagenesis Based on Multiresidue Sites

    ChemBioChem

    Volume 14, Issue 17, November 25, 2013, Pages: 2301–2309, Dr. Loreto P. Parra, Dr. Rubén Agudo and Prof. Dr. Manfred T. Reetz

    Article first published online : 18 OCT 2013, DOI: 10.1002/cbic.201300486

  11. Enhancing the Efficiency of Directed Evolution in Focused Enzyme Libraries by the Adaptive Substituent Reordering Algorithm

    Chemistry - A European Journal

    Volume 18, Issue 18, April 27, 2012, Pages: 5646–5654, Dr. Xiaojiang Feng, Dr. Joaquin Sanchis, Dr. Manfred T. Reetz and Dr. Herschel Rabitz

    Article first published online : 20 MAR 2012, DOI: 10.1002/chem.201103811

  12. Protein Engineering of Stereoselective Baeyer–Villiger Monooxygenases

    Chemistry - A European Journal

    Volume 18, Issue 33, August 13, 2012, Pages: 10160–10172, Dr. Zhi-Gang Zhang, Dr. Loreto P. Parra and Prof. Dr. Manfred T. Reetz

    Article first published online : 16 JUL 2012, DOI: 10.1002/chem.201202163

  13. Revisiting the Lipase from Pseudomonas aeruginosa: Directed Evolution of Substrate Acceptance and Enantioselectivity Using Iterative Saturation Mutagenesis

    ChemPhysChem

    Volume 12, Issue 8, June 6, 2011, Pages: 1550–1557, Dr. Shreenath Prasad, Dr. Marco Bocola and Prof. Dr. Manfred T. Reetz

    Article first published online : 5 APR 2011, DOI: 10.1002/cphc.201100031

  14. New Generation of Biocatalysts for Organic Synthesis

    Angewandte Chemie International Edition

    Volume 53, Issue 12, March 17, 2014, Pages: 3070–3095, Bettina M. Nestl, Stephan C. Hammer, Bernd A. Nebel and Prof. Dr. Bernhard Hauer

    Article first published online : 12 FEB 2014, DOI: 10.1002/anie.201302195

  15. The Importance of Additive and Non-Additive Mutational Effects in Protein Engineering

    Angewandte Chemie International Edition

    Volume 52, Issue 10, March 4, 2013, Pages: 2658–2666, Prof. Dr. Manfred T. Reetz

    Article first published online : 4 FEB 2013, DOI: 10.1002/anie.201207842

  16. Alteration of Substrate Specificity and Stereoselectivity of Lipases and Esterases

    Protein Engineering Handbook, Volume 1 & Volume 2

    Dominique Böttcher, Marlen Schmidt, Uwe T. Bornscheuer, Pages: 753–775, 2011

    Published Online : 9 MAR 2011, DOI: 10.1002/9783527634026.ch30

  17. Mutations in Distant Residues Moderately Increase the Enantioselectivity of Pseudomonas fluorescens Esterase towards Methyl 3Bromo-2-methylpropanoate and Ethyl 3Phenylbutyrate

    Chemistry - A European Journal

    Volume 9, Issue 9, May 9, 2003, Pages: 1933–1939, Geoff P. Horsman, Andrew M. F. Liu, Erik Henke, Uwe T. Bornscheuer and Romas J. Kazlauskas

    Article first published online : 9 APR 2003, DOI: 10.1002/chem.200204551

  18. Single active-site mutants are sufficient to enhance serine:pyruvate α-transaminase activity in an ω-transaminase

    The FEBS Journal

    Volume 282, Issue 13, July 2015, Pages: 2512–2526, Dawid Deszcz, Pierre Affaticati, Nadine Ladkau, Alex Gegel, John M. Ward, Helen C. Hailes and Paul A. Dalby

    Article first published online : 23 APR 2015, DOI: 10.1111/febs.13293

  19. Discovery and Protein Engineering of Biocatalysts for Organic Synthesis

    Advanced Synthesis & Catalysis

    Volume 353, Issue 13, September 2011, Pages: 2191–2215, Geoffrey A. Behrens, Anke Hummel, Santosh K. Padhi, Sebastian Schätzle and Uwe T. Bornscheuer

    Article first published online : 5 SEP 2011, DOI: 10.1002/adsc.201100446

  20. Finding the Selectivity Switch – A Rational Approach towards Stereocomplementary Variants of the Ene Reductase YqjM

    Advanced Synthesis & Catalysis

    Volume 357, Issue 8, May 26, 2015, Pages: 1775–1786, Elisabeth Rüthlein, Thomas Classen, Lina Dobnikar, Melanie Schölzel and Jörg Pietruszka

    Article first published online : 29 APR 2015, DOI: 10.1002/adsc.201500149