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There are 66598 results for: content related to: Unique Gene-Silencing and Structural Properties of 2′-Fluoro-Modified siRNAs

  1. Unique Gene-Silencing and Structural Properties of 2′-Fluoro-Modified siRNAs

    Angewandte Chemie

    Volume 123, Issue 10, March 1, 2011, Pages: 2332–2336, Dr. Muthiah Manoharan, Dr. Akin Akinc, Dr. Rajendra K. Pandey, June Qin, Dr. Philipp Hadwiger, Dr. Matthias John, Kathy Mills, Dr. Klaus Charisse, Dr. Martin A. Maier, Dr. Lubomir Nechev, Emily M. Greene, Dr. Pradeep S. Pallan, Prof. Eriks Rozners, Dr. Kallanthottathil G. Rajeev and Prof. Martin Egli

    Version of Record online : 31 JAN 2011, DOI: 10.1002/ange.201006519

  2. Fully 2′-Deoxy-2′-Fluoro Substituted Nucleic Acids Induce RNA Interference in Mammalian Cell Culture

    Chemical Biology & Drug Design

    Volume 70, Issue 2, August 2007, Pages: 113–122, Richard A. Blidner, Robert P. Hammer, Mandi J. Lopez, Sandra O. Robinson and W. Todd Monroe

    Version of Record online : 26 JUL 2007, DOI: 10.1111/j.1747-0285.2007.00542.x

  3. Exploring Chemical Modifications for siRNA Therapeutics: A Structural and Functional Outlook

    ChemMedChem

    Volume 5, Issue 3, March 1, 2010, Pages: 328–349, Siddharth Shukla, Chintan S. Sumaria and P. I. Pradeepkumar

    Version of Record online : 30 DEC 2009, DOI: 10.1002/cmdc.200900444

  4. RNA Metabolism and Drug Design

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    Reviews in Cell Biology and Molecular Medicine

    Eriks Rozners

    Published Online : 5 OCT 2015, DOI: 10.1002/3527600906.mcb.201500015

  5. Recent attempts at RNAi-mediated P-glycoprotein downregulation for reversal of multidrug resistance in cancer

    Medicinal Research Reviews

    Volume 33, Issue 1, January 2013, Pages: 33–53, Meysam Abbasi, Afsaneh Lavasanifar and Hasan Uludaˇ

    Version of Record online : 26 APR 2011, DOI: 10.1002/med.20244

  6. Effect of North Bicyclo[3.1.0]hexane 2′-Deoxy-pseudosugars on RNA Interference: A Novel Class of siRNA Modification

    ChemBioChem

    Volume 12, Issue 7, May 2, 2011, Pages: 1056–1065, Dr. Montserrat Terrazas, Dr. Sandra M. Ocampo, Dr. José Carlos Perales, Prof. Dr. Victor E. Marquez and Dr. Ramon Eritja

    Version of Record online : 30 MAR 2011, DOI: 10.1002/cbic.201000791

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    Single-stranded small interfering RNA are more immunostimulatory than their double-stranded counterparts: A central role for 2′-hydroxyl uridines in immune responses

    European Journal of Immunology

    Volume 36, Issue 5, May 2006, Pages: 1222–1230, Mouldy Sioud

    Version of Record online : 11 APR 2006, DOI: 10.1002/eji.200535708

  8. Aptamers as Drug Delivery Vehicles

    ChemMedChem

    Volume 9, Issue 9, September 2014, Pages: 1998–2011, Sven Kruspe, Florian Mittelberger, Kristina Szameit and Prof. Dr. Ulrich Hahn

    Version of Record online : 11 AUG 2014, DOI: 10.1002/cmdc.201402163

  9. Chemical Modification of siRNA

    Unit

    Current Protocols in Nucleic Acid Chemistry

    16:16.3.1–16.3.22

    Glen F. Deleavey, Jonathan K. Watts and Masad J. Damha

    Published Online : 1 DEC 2009, DOI: 10.1002/0471142700.nc1603s39

  10. Synthesis of Site-Specifically Phosphate-Caged siRNAs and Evaluation of Their RNAi Activity and Stability

    Chemistry - A European Journal

    Volume 20, Issue 38, September 15, 2014, Pages: 12114–12122, Dr. Li Wu, Fen Pei, Jinhao Zhang, Junzhou Wu, Mengke Feng, Yuan Wang, Dr. Hongwei Jin, Prof. Liangren Zhang and Prof. Xinjing Tang

    Version of Record online : 1 AUG 2014, DOI: 10.1002/chem.201403430

  11. Pharmacokinetics Of Nucleic-Acid-Based Therapeutics

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    Pharmaceutical Sciences Encyclopedia

    John C. Schmitz, Aleksandra Pandyra, James Koropatnick and Randal W. Berg

    Published Online : 15 MAR 2010, DOI: 10.1002/9780470571224.pse322

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    2′-fucosyllactose: an abundant, genetically determined soluble glycan present in human milk

    Nutrition Reviews

    Volume 71, Issue 12, December 2013, Pages: 773–789, Esther Castanys-Muñoz, Maria J Martin and Pedro Antonio Prieto

    Version of Record online : 18 NOV 2013, DOI: 10.1111/nure.12079

  13. 2′-Fluoro RNA Shows Increased Watson–Crick H-Bonding Strength and Stacking Relative to RNA: Evidence from NMR and Thermodynamic Data

    Angewandte Chemie

    Volume 124, Issue 47, November 19, 2012, Pages: 12033–12036, Dr. Amritraj Patra, Michael Paolillo, Dr. Klaus Charisse, Dr. Muthiah Manoharan, Prof. Eriks Rozners and Prof. Martin Egli

    Version of Record online : 10 OCT 2012, DOI: 10.1002/ange.201204946

  14. 2′-Fluoro RNA Shows Increased Watson–Crick H-Bonding Strength and Stacking Relative to RNA: Evidence from NMR and Thermodynamic Data

    Angewandte Chemie International Edition

    Volume 51, Issue 47, November 19, 2012, Pages: 11863–11866, Dr. Amritraj Patra, Michael Paolillo, Dr. Klaus Charisse, Dr. Muthiah Manoharan, Prof. Eriks Rozners and Prof. Martin Egli

    Version of Record online : 10 OCT 2012, DOI: 10.1002/anie.201204946

  15. Formulation approaches to short interfering RNA and MicroRNA: Challenges and implications

    Journal of Pharmaceutical Sciences

    Volume 101, Issue 11, November 2012, Pages: 4046–4066, Diana Guzman-Villanueva, Ibrahim M. El-Sherbiny, Dea Herrera-Ruiz, Alexander V. Vlassov and Hugh D. C. Smyth

    Version of Record online : 28 AUG 2012, DOI: 10.1002/jps.23300

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    Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication

    Hepatology

    Volume 41, Issue 6, June 2005, Pages: 1349–1356, David V. Morrissey, Karin Blanchard, Lucinda Shaw, Kristi Jensen, Jennifer A. Lockridge, Brent Dickinson, James A. McSwiggen, Chandra Vargeese, Keith Bowman, Chris S. Shaffer, Barry A. Polisky and Shawn Zinnen

    Version of Record online : 2 MAY 2005, DOI: 10.1002/hep.20702

  17. Detection of cytolethal distending toxin activity and cdt genes in Actinobacillus actinomycetemcomitans isolates from geographically diverse populations

    Oral Microbiology and Immunology

    Volume 17, Issue 4, August 2002, Pages: 231–238, A. S. Fabris, J. M. DiRienzo, M. Wïkstrom and M. P. A. Mayer

    Version of Record online : 17 JUL 2002, DOI: 10.1034/j.1399-302X.2002.170405.x

  18. siRNA and RNAi optimization

    Wiley Interdisciplinary Reviews: RNA

    Volume 7, Issue 3, May/June 2016, Pages: 316–329, Adele Alagia and Ramon Eritja

    Version of Record online : 2 FEB 2016, DOI: 10.1002/wrna.1337

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    Differential methylation of the micro-RNA 7b gene targets postnatal maturation of murine neuronal Mecp2 gene expression

    Developmental Neurobiology

    Volume 74, Issue 4, April 2014, Pages: 407–425, Yongjun Chen, Bo-Chul Shin, Shanthie Thamotharan and Sherin U. Devaskar

    Version of Record online : 9 DEC 2013, DOI: 10.1002/dneu.22126

  20. Nanoparticle Conjugates for Small Interfering RNA Delivery

    Standard Article

    Reviews in Cell Biology and Molecular Medicine

    Timothy L. Sita and Alexander H. Stegh

    Published Online : 28 APR 2015, DOI: 10.1002/3527600906.mcb.201500006