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There are 8726 results for: content related to: Immunosuppressive Small Molecule Discovered by Structure-Based Virtual Screening for Inhibitors of Protein–Protein Interactions

  1. Identifizierung eines immunsuppressiven Wirkstoffmoleküls durch strukturbasiertes virtuelles Screening nach Inhibitoren von Protein-Protein-Wechselwirkungen

    Angewandte Chemie

    Volume 124, Issue 1, January 2, 2012, Pages: 264–268, Tim Geppert, Stefanie Bauer, Dr. Jan A. Hiss, Elea Conrad, Michael Reutlinger, Dr. Petra Schneider, Dr. Martin Weisel, Bernhard Pfeiffer, Prof. Dr. Karl-Heinz Altmann, Priv.-Doz. Dr. Zoe Waibler and Prof. Dr. Gisbert Schneider

    Article first published online : 16 NOV 2011, DOI: 10.1002/ange.201105901

  2. Initial expression of interferon alpha receptor 2 (IFNAR2) on CD34-positive cells and its down-regulation correlate with clinical response to interferon therapy in chronic myelogenous leukemia

    European Journal of Haematology

    Volume 73, Issue 3, September 2004, Pages: 191–205, Kinro Ito, Hideo Tanaka, Takuo Ito, Tanvira A. Sultana, Taiichi Kyo, Fumio Imanaka, Yasukazu Ohmoto and Akiro Kimura

    Article first published online : 30 JUL 2004, DOI: 10.1111/j.1600-0609.2004.00275.x

  3. You have full text access to this OnlineOpen article
    Influence of type-I Interferon receptor expression level on the response to type-I Interferons in human pancreatic cancer cells

    Journal of Cellular and Molecular Medicine

    Volume 18, Issue 3, March 2014, Pages: 492–502, Stephanie Booy, Casper H. J. van Eijck, Fadime Dogan, Peter M. van Koetsveld and Leo J. Hofland

    Article first published online : 25 JAN 2014, DOI: 10.1111/jcmm.12200

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    The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression

    The EMBO Journal

    Volume 22, Issue 3, February 3, 2003, Pages: 537–547, Josiane Ragimbeau, Elisabetta Dondi, Andrés Alcover, Pierre Eid, Gilles Uzé and Sandra Pellegrini

    Article first published online : 3 FEB 2003, DOI: 10.1093/emboj/cdg038

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    Deficiency of the type I interferon receptor protects mice from experimental lupus

    Arthritis & Rheumatism

    Volume 56, Issue 11, November 2007, Pages: 3770–3783, Dina C. Nacionales, Kindra M. Kelly-Scumpia, Pui Y. Lee, Jason S. Weinstein, Robert Lyons, Eric Sobel, Minoru Satoh and Westley H. Reeves

    Article first published online : 29 OCT 2007, DOI: 10.1002/art.23023

  6. Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation

    Immunological Reviews

    Volume 250, Issue 1, November 2012, Pages: 317–334, Jacob Piehler, Christoph Thomas, K.Christopher Garcia and Gideon Schreiber

    Article first published online : 10 OCT 2012, DOI: 10.1111/imr.12001

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    Kinetic analysis of cytokine-mediated receptor assembly using engineered FC heterodimers

    Protein Science

    Volume 22, Issue 8, August 2013, Pages: 1100–1108, Ashlesha Deshpande, Balananda-Dhurjati Kumar Putcha, Srilalitha Kuruganti and Mark R. Walter

    Article first published online : 6 JUN 2013, DOI: 10.1002/pro.2285

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    Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics

    European Journal of Immunology

    Volume 44, Issue 8, August 2014, Pages: 2380–2393, Anca Dorhoi, Vladimir Yeremeev, Geraldine Nouailles, January Weiner 3rd, Sabine Jörg, Ellen Heinemann, Dagmar Oberbeck-Müller, Julia K. Knaul, Alexis Vogelzang, Stephen T. Reece, Karin Hahnke, Hans-Joachim Mollenkopf, Volker Brinkmann and Stefan H. E. Kaufmann

    Article first published online : 24 JUN 2014, DOI: 10.1002/eji.201344219

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    Concomitant type I IFN receptor-triggering of T cells and of DC is required to promote maximal modified vaccinia virus Ankara-induced T-cell expansion

    European Journal of Immunology

    Volume 40, Issue 10, October 2010 , Pages: 2769–2777, Theresa Frenz, Zoe Waibler, Janin Hofmann, Matthias Hamdorf, Markus Lantermann, Boris Reizis, Michaël G. Tovey, Peter Aichele, Gerd Sutter and Ulrich Kalinke

    Article first published online : 6 SEP 2010, DOI: 10.1002/eji.201040453

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    Protection against RNA-induced liver damage by myeloid cells requires type I interferon and IL-1 receptor antagonist in mice

    Hepatology

    Volume 59, Issue 4, April 2014, Pages: 1555–1563, Elea Conrad, Theresa K. Resch, Patricia Gogesch, Ulrich Kalinke, Ingo Bechmann, Christian Bogdan and Zoe Waibler

    Article first published online : 28 FEB 2014, DOI: 10.1002/hep.26915

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    SCFHOS ubiquitin ligase mediates the ligand-induced down-regulation of the interferon-α receptor

    The EMBO Journal

    Volume 22, Issue 20, October 15, 2003, Pages: 5480–5490, K.G.Suresh Kumar, Weigang Tang, Abhilash K. Ravindranath, William A. Clark, Ed Croze and Serge Y. Fuchs

    Article first published online : 15 OCT 2003, DOI: 10.1093/emboj/cdg524

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    Critical role for constitutive type I interferon signaling in the prevention of cellular transformation

    Cancer Science

    Volume 100, Issue 3, March 2009, Pages: 449–456, Hui-min Chen, Nobuyuki Tanaka, Yukiko Mitani, Eri Oda, Hiroaki Nozawa, Jian-zhong Chen, Hideyuki Yanai, Hideo Negishi, Myoung Kwon Choi, Toshiroh Iwasaki, Hiroyuki Yamamoto, Tadatsugu Taniguchi and Akinori Takaoka

    Article first published online : 14 DEC 2008, DOI: 10.1111/j.1349-7006.2008.01051.x

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    Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury

    EMBO Molecular Medicine

    Volume 6, Issue 3, March 2014, Pages: 384–397, Sabyasachi Bhattacharya, Kanstantsin V Katlinski, Maximilian Reichert, Shigetsugu Takano, Angela Brice, Bin Zhao, Qiujing Yu, Hui Zheng, Christopher J Carbone, Yuliya V Katlinskaya, N Adrian Leu, Kelly A McCorkell, Satish Srinivasan, Melanie Girondo, Hallgeir Rui, Michael J May, Narayan G Avadhani, Anil K Rustgi and Serge Y Fuchs

    Article first published online : 31 JAN 2014, DOI: 10.1002/emmm.201303236

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    Down-regulation of type I interferon receptor sensitizes bladder cancer cells to vesicular stomatitis virus-induced cell death

    International Journal of Cancer

    Volume 127, Issue 4, 15 August 2010, Pages: 830–838, Kai-xin Zhang, Yoshiyuki Matsui, Boris A. Hadaschik, Cleo Lee, William Jia, John C. Bell, Ladan Fazli, Alan I. So and Paul S. Rennie

    Article first published online : 2 DEC 2009, DOI: 10.1002/ijc.25088

  15. A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic hepatitis B virus infection

    Journal of Viral Hepatitis

    Volume 16, Issue 1, January 2009, Pages: 45–52, J. Zhou, D. K. Smith, L. Lu, V. K. M. Poon, F. Ng, D.-Q. Chen, J.-D. Huang, K.-Y. Yuen, K.-Y. Cao and B.-J. Zheng

    Article first published online : 28 AUG 2008, DOI: 10.1111/j.1365-2893.2008.01040.x

  16. Endometrial Expression of IFNAR-1 and Oxytocin Receptor (OTR) is not Improved by Prostaglandin Analogues when Compared to Progestagens in Ewes

    Reproduction in Domestic Animals

    Volume 47, Issue 2, April 2012, Pages: 274–280, I Ruiz-González, MA Sánchez, RA García-Fernández, P García-Palencia, B Sánchez, CA Letelier, A González-Bulnes and JM Flores

    Article first published online : 19 JUL 2011, DOI: 10.1111/j.1439-0531.2011.01852.x

  17. cDNA cloning, genomic structure and mRNA expression pattern of porcine type I interferons receptor 2 gene

    International Journal of Immunogenetics

    Volume 38, Issue 4, August 2011, Pages: 339–345, F. Xing, Y. Li, S. Liang, D. Liu, C. Jiang, Y. Zhang, L. Kang and Y. Jiang

    Article first published online : 7 JUN 2011, DOI: 10.1111/j.1744-313X.2011.01018.x

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    Activation of IL-27 signalling promotes development of postinfluenza pneumococcal pneumonia

    EMBO Molecular Medicine

    Volume 6, Issue 1, January 2014, Pages: 120–140, Ju Cao, Dongsheng Wang, Fang Xu, Yi Gong, Hong Wang, Zixin Song, Dageng Li, Hua Zhang, Dairong Li, Liping Zhang, Yun Xia, Huajian Xu, Xaiofei Lai, Shihui Lin, Xuemei Zhang, Guosheng Ren, Yubing Dai and Yibing Yin

    Article first published online : 29 OCT 2013, DOI: 10.1002/emmm.201302890

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    Toll-like receptor 7-mediated type I interferon signaling prevents cholestasis- and hepatotoxin-induced liver fibrosis

    Hepatology

    Volume 60, Issue 1, July 2014, Pages: 237–249, Yoon Seok Roh, Surim Park, Jong Won Kim, Chae Woong Lim, Ekihiro Seki and Bumseok Kim

    Article first published online : 27 MAY 2014, DOI: 10.1002/hep.26981

  20. Interferon alpha receptors are important for antiproliferative effect of interferon-α against human hepatocellular carcinoma cells

    Hepatology Research

    Volume 37, Issue 1, January 2007, Pages: 77–83, Bazarragchaa Damdinsuren, Hiroaki Nagano, Hiroshi Wada, Takehiro Noda, Javzandulam Natsag, Shigeru Marubashi, Atsushi Miyamoto, Yutaka Takeda, Koji Umeshita, Yuichiro Doki, Keizo Dono and Morito Monden

    Article first published online : 1 FEB 2007, DOI: 10.1111/j.1872-034X.2007.00007.x