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There are 12810 results for: content related to: Using Ligand-Mapping Simulations to Design a Ligand Selectively Targeting a Cryptic Surface Pocket of Polo-Like Kinase 1

  1. You have full text access to this OnlineOpen article
    Using Ligand-Mapping Simulations to Design a Ligand Selectively Targeting a Cryptic Surface Pocket of Polo-Like Kinase 1

    Angewandte Chemie

    Volume 124, Issue 40, October 1, 2012, Pages: 10225–10228, Yaw Sing Tan, Dr. Paweł Śledź, Dr. Steffen Lang, Christopher J. Stubbs, Dr. David R. Spring, Prof. Chris Abell and Dr. Robert B. Best

    Version of Record online : 7 SEP 2012, DOI: 10.1002/ange.201205676

  2. You have full text access to this OnlineOpen article
    From Crystal Packing to Molecular Recognition: Prediction and Discovery of a Binding Site on the Surface of Polo-Like Kinase 1

    Angewandte Chemie International Edition

    Volume 50, Issue 17, April 18, 2011, Pages: 4003–4006, Paweł Śledź, Christopher J. Stubbs, Dr. Steffen Lang, Dr. Yong-Qing Yang, Dr. Grahame J. McKenzie, Prof. Ashok R. Venkitaraman, Dr. Marko Hyvönen and Prof. Chris Abell

    Version of Record online : 29 MAR 2011, DOI: 10.1002/anie.201008019

  3. You have full text access to this OnlineOpen article
    From Crystal Packing to Molecular Recognition: Prediction and Discovery of a Binding Site on the Surface of Polo-Like Kinase 1

    Angewandte Chemie

    Volume 123, Issue 17, April 18, 2011, Pages: 4089–4092, Paweł Śledź, Christopher J. Stubbs, Dr. Steffen Lang, Dr. Yong-Qing Yang, Dr. Grahame J. McKenzie, Prof. Ashok R. Venkitaraman, Dr. Marko Hyvönen and Prof. Chris Abell

    Version of Record online : 29 MAR 2011, DOI: 10.1002/ange.201008019

  4. You have free access to this content
    The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex

    The EMBO Journal

    Volume 22, Issue 21, November 3, 2003, Pages: 5757–5768, Kin-Yip Cheng, Edward D Lowe, John Sinclair, Erich A Nigg and Louise N Johnson

    Version of Record online : 3 NOV 2003, DOI: 10.1093/emboj/cdg558

  5. Rational Molecular Design of Potent PLK1 PBD Domain-binding Phosphopeptides Using Preferential Amino Acid Building Blocks

    Chemistry & Biodiversity

    Volume 13, Issue 8, August 2016, Pages: 1103–1110, Xin-Li Mao, Kui-Feng Wang, Feng Zhu, Zhao-Hu Pan, Guo-Min Wu and Hong-Yuan Zhu

    Version of Record online : 12 AUG 2016, DOI: 10.1002/cbdv.201500513

  6. The Tyrosine Gate of the Bacterial Lectin FimH: A Conformational Analysis by NMR Spectroscopy and X-ray Crystallography

    ChemBioChem

    Volume 16, Issue 8, May 26, 2015, Pages: 1235–1246, Dr. Brigitte Fiege, Dr. Said Rabbani, Dr. Roland C. Preston, Dr. Roman P. Jakob, Pascal Zihlmann, Dr. Oliver Schwardt, Dr. Xiaohua Jiang, Prof. Timm Maier and Prof. Beat Ernst

    Version of Record online : 4 MAY 2015, DOI: 10.1002/cbic.201402714

  7. You have free access to this content
    Phenylmethanesulfonyl fluoride inactivates an archaeal superoxide dismutase by chemical modification of a specific tyrosine residue

    European Journal of Biochemistry

    Volume 268, Issue 6, March 2001, Pages: 1794–1801, Emmanuele De Vendittis, Thomas Ursby, Rosario Rullo, Maria Angela Gogliettino, Mariorosario Masullo and Vincenzo Bocchini

    Version of Record online : 15 DEC 2003, DOI: 10.1046/j.1432-1327.2001.02052.x

  8. Helix formation is a dynamical bottleneck in the recovery reaction of Photoactive Yellow Protein

    Proteins: Structure, Function, and Bioinformatics

    Volume 72, Issue 1, July 2008, Pages: 136–149, Jocelyne Vreede, Klaas J. Hellingwerf and Peter G. Bolhuis

    Version of Record online : 23 JAN 2008, DOI: 10.1002/prot.21902

  9. Functional assessment of “in vivo” and “in silico” mutations in the guanine binding site of RNase T1: A DFT study

    International Journal of Quantum Chemistry

    Volume 99, Issue 1, 2004, Pages: 53–58, Pierre Mignon, Stefan Loverix, Jan Steyaert and Paul Geerlings

    Version of Record online : 26 APR 2004, DOI: 10.1002/qua.20114

  10. Flexibility and charge asymmetry in the activation loop of Src tyrosine kinases

    Proteins: Structure, Function, and Bioinformatics

    Volume 74, Issue 2, 1 February 2009, Pages: 378–389, Nilesh K. Banavali and Benoît Roux

    Version of Record online : 11 JUL 2008, DOI: 10.1002/prot.22153

  11. You have free access to this content
    Crystal structure of the Tyr45Trp mutant of ribonuclease T1 in a complex with 2′-adenylic acid

    European Journal of Biochemistry

    Volume 201, Issue 1, October 1991, Pages: 199–202, Gertraude KOELLNER, Hans-Peter GRUNERT, Olfert LANDT and Wolfram SAENGER

    Version of Record online : 3 MAR 2005, DOI: 10.1111/j.1432-1033.1991.tb16274.x

  12. You have free access to this content
    Modelling the catalytic reaction in human aldose reductase

    Proteins: Structure, Function, and Bioinformatics

    Volume 37, Issue 2, 1 November 1999, Pages: 218–227, Péter Várnai, W. Graham Richards and Paul D. Lyne

    Version of Record online : 2 DEC 1999, DOI: 10.1002/(SICI)1097-0134(19991101)37:2<218::AID-PROT7>3.0.CO;2-E

  13. Pyrrole-Based, Macrocyclic, Small-Molecule Inhibitors Targeting Oocyte Maturation

    ChemMedChem

    Accepted manuscript online: 12 MAR 2017, Jeong Kyu Bang, Pethaiah Gunasekaran, So Rim Lee, Seung-min Jeong, Jeong-woo Kwon, Toshiki Takei, Yuya Asahina, Geul Bang, Seongnyeon Kim, Mija Ahn, Eun Kyung Ryu, Hak Nam Kim, Ki-Yub Nam, Song Yub Shin, Hironobu Hojo, Suk Namgoong and Nam-Hyung Kim

    DOI: 10.1002/cmdc.201700048

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    Dma1 ubiquitinates the SIN scaffold, Sid4, to impede the mitotic localization of Plo1 kinase

    The EMBO Journal

    Volume 30, Issue 2, January 19, 2011, Pages: 341–354, Alyssa E Johnson and Kathleen L Gould

    Version of Record online : 3 DEC 2010, DOI: 10.1038/emboj.2010.317

  15. Structural analysis of the polo-box domain of human Polo-like kinase 2

    Proteins: Structure, Function, and Bioinformatics

    Volume 83, Issue 7, July 2015, Pages: 1201–1208, Ju Hee Kim, Bonsu Ku, Kyung S. Lee and Seung Jun Kim

    Version of Record online : 28 APR 2015, DOI: 10.1002/prot.24804

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    Intermolecular interactions in staphylokinase–plasmin(ogen) bimolecular complex: Function of His43 and Tyr44

    FEBS Letters

    Volume 585, Issue 12, June 23, 2011, Pages: 1814–1820, Monika Dahiya, Satish Singh, Govindan Rajamohan, Deepti Sethi, Ashish and Kanak L. Dikshit

    Version of Record online : 16 APR 2011, DOI: 10.1016/j.febslet.2011.04.030

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    Re- or displacement of invariant residues in the C-terminal half of the catalytic domain strongly affects catalysis by glucosyltransferase R

    FEBS Letters

    Volume 582, Issue 4, February 20, 2008, Pages: 491–496, Sabine Wittrock, Anna Maria Swistowska, Wera Collisi, Birgit Hofmann, Hans-Jürgen Hecht and Bernd Hofer

    Version of Record online : 17 JAN 2008, DOI: 10.1016/j.febslet.2007.12.040

  18. Differential Cellular Effects of Plk1 Inhibitors Targeting the ATP-binding Domain or Polo-box Domain

    Journal of Cellular Physiology

    Volume 230, Issue 12, December 2015, Pages: 3057–3067, Sol-Bi Shin, Sang-Uk Woo and Hyungshin Yim

    Version of Record online : 24 AUG 2015, DOI: 10.1002/jcp.25042

  19. You have free access to this content
    Backdoor opening mechanism in acetylcholinesterase based on X-ray crystallography and molecular dynamics simulations

    Protein Science

    Volume 20, Issue 7, July 2011, Pages: 1114–1118, Benoît Sanson, Jacques-Philippe Colletier, Yechun Xu, P. Therese Lang, Hualiang Jiang, Israel Silman, Joel L. Sussman and Martin Weik

    Version of Record online : 10 JUN 2011, DOI: 10.1002/pro.661

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    The polo-like kinase PLKA is required for initiation and progression through mitosis in the filamentous fungus Aspergillus nidulans

    Molecular Microbiology

    Volume 55, Issue 2, January 2005, Pages: 572–587, Catherine Bachewich, Kathryn Masker and Stephen Osmani

    Version of Record online : 2 DEC 2004, DOI: 10.1111/j.1365-2958.2004.04404.x