Search Results

There are 39342 results for: content related to: Substrate Selectivity Analyses of Factor Inhibiting Hypoxia-Inducible Factor

  1. You have full text access to this OnlineOpen article
    Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains

    FEBS Journal

    Volume 278, Issue 7, April 2011, Pages: 1086–1097, Ming Yang, Rasheduzzaman Chowdhury, Wei Ge, Refaat B. Hamed, Michael A. McDonough, Timothy D. W. Claridge, Benedikt M. Kessler, Matthew E. Cockman, Peter J. Ratcliffe and Christopher J. Schofield

    Article first published online : 23 FEB 2011, DOI: 10.1111/j.1742-4658.2011.08022.x

  2. You have free access to this content
    Inhibitor of nuclear factor-kappaB alpha derepresses hypoxia-inducible factor-1 during moderate hypoxia by sequestering factor inhibiting hypoxia-inducible factor from hypoxia-inducible factor 1α

    FEBS Journal

    Volume 276, Issue 13, July 2009, Pages: 3470–3480, Dong Hoon Shin, Shan Hua Li, Seung-Won Yang, Byung Lan Lee, Myung Kyu Lee and Jong-Wan Park

    Article first published online : 18 MAY 2009, DOI: 10.1111/j.1742-4658.2009.07069.x

  3. Substrate Selectivity Analyses of Factor Inhibiting Hypoxia-Inducible Factor

    Angewandte Chemie

    Volume 125, Issue 6, February 4, 2013, Pages: 1744–1748, Dr. Ming Yang, Dr. Adam P. Hardy, Dr. Rasheduzzaman Chowdhury, Nikita D. Loik, John S. Scotti, Dr. James S. O. McCullagh, Dr. Timothy D. W. Claridge, Dr. Michael A. McDonough, Dr. Wei Ge and Prof. Dr. Christopher J. Schofield

    Article first published online : 7 JAN 2013, DOI: 10.1002/ange.201208046

  4. You have free access to this content
    Overexpression of factor inhibiting HIF-1 enhances vessel maturation and tumor growth via platelet-derived growth factor-C

    International Journal of Cancer

    Volume 131, Issue 5, 1 September 2012, Pages: E603–E613, Aleksandar Kuzmanov, Ben Wielockx, Maryam Rezaei, Antje Kettelhake and Georg Breier

    Article first published online : 3 JAN 2012, DOI: 10.1002/ijc.27360

  5. FIH-Dependent Asparaginyl Hydroxylation of Ankyrin Repeat Domain-Containing Proteins

    Annals of the New York Academy of Sciences

    Volume 1177, Issue 1, October 2009, Pages: 9–18, Matthew E. Cockman, James D. Webb and Peter J. Ratcliffe

    Article first published online : 15 OCT 2009, DOI: 10.1111/j.1749-6632.2009.05042.x

  6. Co-targeting of multiple microrNAs on factor-Inhibiting hypoxia-Inducible factor gene for the pathogenesis of head and neck carcinomas

    Head & Neck

    Shou-Yen Kao, Meng-Miao Tsai, Cheng-Hsieh Wu, Jing-Jung Chen, Ssu-Hsueh Tseng, Shu-Chun Lin and Kuo-Wei Chang

    Article first published online : 16 JUN 2015, DOI: 10.1002/hed.23912

  7. You have full text access to this OnlineOpen article
    The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity

    EMBO reports

    Volume 13, Issue 3, March 2012, Pages: 251–257, Norma Masson, Rachelle S Singleton, Rok Sekirnik, David C Trudgian, Lucy J Ambrose, Melroy X Miranda, Ya-Min Tian, Benedikt M Kessler, Christopher J Schofield and Peter J Ratcliffe

    Article first published online : 7 FEB 2012, DOI: 10.1038/embor.2012.9

  8. Differential in vitro and cellular effects of iron chelators for hypoxia inducible factor hydroxylases

    Journal of Cellular Biochemistry

    Volume 114, Issue 4, April 2013, Pages: 864–873, Eun A. Cho, Hyun Kyung Song, Sang-Hyeup Lee, Bong Hyun Chung, Heon Man Lim and Myung Kyu Lee

    Article first published online : 18 FEB 2013, DOI: 10.1002/jcb.24423

  9. You have free access to this content
    Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation

    European Journal of Biochemistry

    Volume 270, Issue 5, March 2003, Pages: 781–790, David Lando, Jeffrey J. Gorman, Murray L. Whitelaw and Daniel J. Peet

    Article first published online : 10 SEP 2003, DOI: 10.1046/j.1432-1033.2003.03445.x

  10. Impaired hypoxic sensor Siah-1, PHD3, and FIH system in spinal motor neurons of an amyotrophic lateral sclerosis mouse model

    Journal of Neuroscience Research

    Volume 91, Issue 2, February 2013, Pages: 285–291, Kota Sato, Nobutoshi Morimoto, Tomoko Kurata, Takafumi Mimoto, Kazunori Miyazaki, Yoshio Ikeda and Koji Abe

    Article first published online : 14 NOV 2012, DOI: 10.1002/jnr.23129

  11. DNA methylation analysis of the HIF-1α prolyl hydroxylase domain genes PHD1, PHD2, PHD3 and the factor inhibiting HIF gene FIH in invasive breast carcinomas

    Histopathology

    Volume 57, Issue 3, September 2010, Pages: 451–460, Katie T Huang, Thomas Mikeska, Alexander Dobrovic and Stephen B Fox

    Article first published online : 19 AUG 2010, DOI: 10.1111/j.1365-2559.2010.03633.x

  12. From Polyps to People

    Annals of the New York Academy of Sciences

    Volume 1177, Issue 1, October 2009, Pages: 19–29, R.J. Hampton-Smith and D.J. Peet

    Article first published online : 15 OCT 2009, DOI: 10.1111/j.1749-6632.2009.05035.x

  13. You have free access to this content
    Poly(ADP-ribose) polymerase-1 modulation of in vivo response of brain hypoxia-inducible factor-1 to hypoxia/reoxygenation is mediated by nitric oxide and factor inhibiting HIF

    Journal of Neurochemistry

    Volume 111, Issue 1, October 2009, Pages: 150–159, Rubén Martínez-Romero, Ana Cañuelo, Esther Martínez-Lara, Francisco Javier Oliver, Sara Cárdenas and Eva Siles

    Article first published online : 27 JUL 2009, DOI: 10.1111/j.1471-4159.2009.06307.x

  14. You have free access to this content
    Prolyl hydroxylase domain enzyme 2 is the major player in regulating hypoxic responses in rheumatoid arthritis

    Arthritis & Rheumatism

    Volume 64, Issue 9, September 2012, Pages: 2856–2867, Barbara Muz, Helene Larsen, Leigh Madden, Serafim Kiriakidis and Ewa M. Paleolog

    Article first published online : 27 AUG 2012, DOI: 10.1002/art.34479

  15. Expressions of hypoxic stress sensor proteins after transient cerebral ischemia in mice

    Journal of Neuroscience Research

    Volume 90, Issue 3, March 2012, Pages: 648–655, Jingwei Shang, Ning Liu, Nobuhito Tanaka and Koji Abe

    Article first published online : 20 DEC 2011, DOI: 10.1002/jnr.22776

  16. Inclusion of Placebos and Blinding for Ascending Dose First-in-Human Studies and Other Underpowered Phase 1 Studies has not been Justified and on Balance is Not Useful

    Basic & Clinical Pharmacology & Toxicology

    Volume 117, Issue 1, July 2015, Pages: 44–51, Dolly A. Parasrampuria and Leslie Z. Benet

    Article first published online : 23 DEC 2014, DOI: 10.1111/bcpt.12352

  17. A Brief Survey of First-in-Human Studies

    The Journal of Clinical Pharmacology

    Volume 51, Issue 7, July 2011, Pages: 988–993, David Wexler and Kirk M. Bertelsen

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270010377631

  18. Non-Clinical Pharmacokinetics, Prediction of Human Pharmacokinetics and First-in-Human Dose Selection for CNTO 5825, an Anti-Interleukin-13 Monoclonal Antibody

    Basic & Clinical Pharmacology & Toxicology

    Ivo P. Nnane, Zhenhua Xu, Honghui Zhou and Hugh M. Davis

    Article first published online : 5 MAR 2015, DOI: 10.1111/bcpt.12391

  19. Dynamic changes in the expression of MicroRNA-31 during inflammatory bowel disease-associated neoplastic transformation

    Inflammatory Bowel Diseases

    Volume 17, Issue 1, January 2011, Pages: 221–231, Alexandru V. Olaru, Florin M. Selaru, Yuriko Mori, Christine Vazquez, Stefan David, Bogdan Paun, Yulan Cheng, Zhe Jin, Jian Yang, Rachana Agarwal, John M. Abraham, Themistocles Dassopoulos, Mary Harris, Theodore M. Bayless, John Kwon, Noam Harpaz, Ferenc Livak and Stephen J. Meltzer

    Article first published online : 1 JUN 2010, DOI: 10.1002/ibd.21359

  20. Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissues

    Histopathology

    Volume 47, Issue 6, December 2005, Pages: 602–610, E J Soilleux, H Turley, Y M Tian, C W Pugh, K C Gatter and A L Harris

    Article first published online : 27 OCT 2005, DOI: 10.1111/j.1365-2559.2005.02280.x