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There are 4968 results for: content related to: Direct Synthesis of Fluorinated Heteroarylether Bioisosteres

  1. Direct Synthesis of Fluorinated Heteroarylether Bioisosteres

    Angewandte Chemie

    Volume 125, Issue 14, April 2, 2013, Pages: 4041–4044, Dr. Qianghui Zhou, Alessandro Ruffoni, Ryan Gianatassio, Dr. Yuta Fujiwara, Dr. Eran Sella, Prof. Dr. Doron Shabat and Prof. Dr. Phil S. Baran

    Article first published online : 4 MAR 2013, DOI: 10.1002/ange.201300763

  2. Heterocycles as Nonclassical Bioisosteres of α-Amino Acids


    Volume 8, Issue 2, February 2013, Pages: 205–215, Christian B. M. Poulie and Prof. Lennart Bunch

    Article first published online : 15 JAN 2013, DOI: 10.1002/cmdc.201200436

  3. Bioisosteres in De Novo Design

    De novo Molecular Design

    Nicholas C. Firth, Julian Blagg, Nathan Brown, Pages: 417–435, 2013

    Published Online : 11 OCT 2013, DOI: 10.1002/9783527677016.ch17

  4. You have full text access to this OnlineOpen article
    Bioisosteric Matrices for Ligands of Serotonin Receptors


    Volume 10, Issue 4, April 2015, Pages: 601–605, Dawid Warszycki, Stefan Mordalski, Jakub Staroń and Prof. Andrzej J. Bojarski

    Article first published online : 13 MAR 2015, DOI: 10.1002/cmdc.201402563

  5. In silico applications of bioisosterism in contemporary medicinal chemistry practice

    Wiley Interdisciplinary Reviews: Computational Molecular Science

    Volume 3, Issue 4, July/August 2013, Pages: 339–354, George Papadatos and Nathan Brown

    Article first published online : 10 MAY 2013, DOI: 10.1002/wcms.1148

  6. Bioisosteric Replacement and Scaffold Hopping in Lead Generation and Optimization

    Molecular Informatics

    Volume 29, Issue 5, May 17, 2010, Pages: 366–385, Sarah R. Langdon, Peter Ertl and Nathan Brown

    Article first published online : 5 MAY 2010, DOI: 10.1002/minf.201000019

  7. Carboxylic Acid (Bio)Isosteres in Drug Design


    Volume 8, Issue 3, March 2013, Pages: 385–395, Dr. Carlo Ballatore, Prof. Donna M. Huryn and Prof. Amos B. Smith III

    Article first published online : 29 JAN 2013, DOI: 10.1002/cmdc.201200585

  8. You have free access to this content
    Front Matter

    Bioisosteres in Medicinal Chemistry

    Nathan Brown, Pages: I–XVIII, 2012

    Published Online : 3 AUG 2012, DOI: 10.1002/9783527654307.fmatter

  9. Novel Hinge-Binding Motifs for Janus Kinase 3 Inhibitors: A Comprehensive Structure–Activity Relationship Study on Tofacitinib Bioisosteres


    Volume 9, Issue 11, November 2014, Pages: 2516–2527, Matthias Gehringer, Michael Forster, Ellen Pfaffenrot, Silke M. Bauer and Prof. Dr. Stefan A. Laufer

    Article first published online : 19 AUG 2014, DOI: 10.1002/cmdc.201402252

  10. Transport characteristics of peptides and peptidomimetics: II. Hydroxyethylamine bioisostere-containing peptidomimetics as substrates for the oligopeptide transporter and P-glycoprotein in the intestinal mucosa

    The Journal of Peptide Research

    Volume 57, Issue 5, May 2001, Pages: 361–373, J. Gao, S.L. Winslow, D. Vander Velde, R.T. Borchardt and J. Aubé

    Article first published online : 17 MAY 2002, DOI: 10.1034/j.1399-3011.2001.00830.x

  11. Investigations on the 4-Quinolone-3-Carboxylic Acid Motif Part 5: Modulation of the Physicochemical Profile of a Set of Potent and Selective Cannabinoid-2 Receptor Ligands through a Bioisosteric Approach


    Volume 7, Issue 5, May 2012, Pages: 920–934, Dr. Claudia Mugnaini, Stefania Nocerino, Valentina Pedani, Dr. Serena Pasquini, Prof. Andrea Tafi, Maria De Chiaro, Dr. Luca Bellucci, Prof. Massimo Valoti, Dr. Francesca Guida, Dr. Livio Luongo, Dr. Stefania Dragoni, Dr. Alessia Ligresti, Dr. Avraham Rosenberg, Dr. Daniele Bolognini, Dr. Maria Grazia Cascio, Prof. Roger G. Pertwee, Dr. Ruin Moaddel, Prof. Sabatino Maione, Dr. Vincenzo Di Marzo and Prof. Federico Corelli

    Article first published online : 2 MAR 2012, DOI: 10.1002/cmdc.201100573

  12. Preclinical Characterization of Acyl Sulfonimidamides: Potential Carboxylic Acid Bioisosteres with Tunable Properties


    Volume 10, Issue 3, March 2015, Pages: 455–460, Dr. Sanjay R. Borhade, Dr. Richard Svensson, Dr. Peter Brandt, Prof. Dr. Per Artursson, Prof. Dr. Per I. Arvidsson and Dr. Anja Sandström

    Article first published online : 28 JAN 2015, DOI: 10.1002/cmdc.201402497

  13. Consequences of Bioisosteric Replacement

    Bioisosteres in Medicinal Chemistry

    Dennis A. Smith, David S. Millan, Pages: 31–51, 2012

    Published Online : 3 AUG 2012, DOI: 10.1002/9783527654307.ch3

  14. Classical Bioisosteres

    Bioisosteres in Medicinal Chemistry

    Caterina Barillari, Nathan Brown, Pages: 15–29, 2012

    Published Online : 3 AUG 2012, DOI: 10.1002/9783527654307.ch2

  15. Bioisosterism: Quantitation of Structure and Property Effects

    Chemistry & Biodiversity

    Volume 1, Issue 1, January 2004, Pages: 138–151, Lemont B. Kier and Lowell H. Hall

    Article first published online : 3 FEB 2004, DOI: 10.1002/cbdv.200490006

  16. Bioisosteres and Scaffold Hopping in Medicinal Chemistry

    Molecular Informatics

    Volume 33, Issue 6-7, June 2014, Pages: 458–462, Nathan Brown

    Article first published online : 2 JUN 2014, DOI: 10.1002/minf.201400037

  17. Role of Side-Chain Bioisosteres in Determining the Binding Affinity of Click Chemistry Derived RGD Peptidomimetics to αvβ3 Integrin

    European Journal of Organic Chemistry

    Volume 2014, Issue 34, December 2014, Pages: 7595–7604, Pierangelo Fabbrizzi, Gloria Menchi, Silvia Raspanti, Antonio Guarna and Andrea Trabocchi

    Article first published online : 24 OCT 2014, DOI: 10.1002/ejoc.201403129

  18. Mining the Cambridge Structural Database for Bioisosteres

    Bioisosteres in Medicinal Chemistry

    Colin R. Groom, Tjelvar S. G. Olsson, John W. Liebeschuetz, David A. Bardwell, Ian J. Bruno, Frank H. Allen, Pages: 75–101, 2012

    Published Online : 3 AUG 2012, DOI: 10.1002/9783527654307.ch5

  19. The Drug Guru Project

    Bioisosteres in Medicinal Chemistry

    Kent D. Stewart, Jason Shanley, Karam B. Alsayyed Ahmed, J. Phillip Bowen, Pages: 183–198, 2012

    Published Online : 3 AUG 2012, DOI: 10.1002/9783527654307.ch11

  20. Pyridones as potential antitumor agents II: 4-pyridones and bioisosteres of 3-acetoxy-2-pyridone

    Journal of Pharmaceutical Sciences

    Volume 69, Issue 9, September 1980, Pages: 1074–1076, Deng R. Hwang, George R. Proctor and John S. Driscoll

    Article first published online : 16 SEP 2006, DOI: 10.1002/jps.2600690923