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There are 5897 results for: content related to: Gout: On the brink of novel therapeutic options for an ancient disease

  1. You have full text access to this OnlineOpen article
    Uricosuric targets of tranilast

    Pharmacology Research & Perspectives

    Volume 5, Issue 2, April 2017, Asim K. Mandal, Adriana Mercado, Andria Foster, Kambiz Zandi-Nejad and David B. Mount

    Version of Record online : 6 FEB 2017, DOI: 10.1002/prp2.291

  2. Uricosuric agents decrease the plasma urate level in rats by concomitant treatment with topiroxostat, a novel xanthine oxidoreductase inhibitor

    Journal of Pharmacy and Pharmacology

    Volume 68, Issue 1, January 2016, Pages: 76–83, Tetsuya Taniguchi, Naoki Ashizawa, Koji Matsumoto, Takashi Iwanaga and Kazuhiro Saitoh

    Version of Record online : 21 NOV 2015, DOI: 10.1111/jphp.12490

  3. Renal Excretion and Tubular Transport of Organic Anions and Cations

    Standard Article

    Comprehensive Physiology

    Françoise Roch-Ramel, Kamel Besseghir and Heini Murer

    Published Online : 1 JAN 2011, DOI: 10.1002/cphy.cp080248

  4. You have free access to this content
    Allopurinol for chronic gout

    Intervention Review

    The Cochrane Library

    Rakhi Seth, Alison SR Kydd, Rachelle Buchbinder, Claire Bombardier and Christopher J Edwards

    Published Online : 14 OCT 2014, DOI: 10.1002/14651858.CD006077.pub3

  5. You have free access to this content
    Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4

    British Journal of Pharmacology

    Volume 155, Issue 7, December 2008, Pages: 1066–1075, A A K El-Sheikh, J J M W Van Den Heuvel, J B Koenderink and F G M Russel

    Version of Record online : 29 JAN 2009, DOI: 10.1038/bjp.2008.343

  6. You have free access to this content
    Protection of dopaminergic cells by urate requires its accumulation in astrocytes

    Journal of Neurochemistry

    Volume 123, Issue 1, October 2012, Pages: 172–181, Sara Cipriani, Cody A. Desjardins, Thomas C. Burdett, Yuehang Xu, Kui Xu and Michael A. Schwarzschild

    Version of Record online : 22 AUG 2012, DOI: 10.1111/j.1471-4159.2012.07820.x

  7. You have free access to this content
    Development of a Dual-Energy Computed Tomography Scoring System for Measurement of Urate Deposition in Gout

    Arthritis Care & Research

    Volume 68, Issue 6, June 2016, Pages: 769–775, Sara Bayat, Opetaia Aati, Jürgen Rech, Mark Sapsford, Alexander Cavallaro, Michael Lell, Elizabeth Araujo, Christina Petsch, Lisa K. Stamp, Georg Schett, Bernhard Manger and Nicola Dalbeth

    Version of Record online : 26 MAY 2016, DOI: 10.1002/acr.22754

  8. You have free access to this content
    Uricosuric medications for chronic gout

    Intervention Review

    The Cochrane Library

    Alison SR Kydd, Rakhi Seth, Rachelle Buchbinder, Christopher J Edwards and Claire Bombardier

    Published Online : 14 NOV 2014, DOI: 10.1002/14651858.CD010457.pub2

  9. You have free access to this content
    Purine-induced expression of urate oxidase and enzyme activity in Atlantic salmon (Salmo salar)

    The FEBS Journal

    Volume 273, Issue 13, July 2006, Pages: 2839–2850, Øivind Andersen, Turid s. Aas, Stanko Skugor, Harald Takle, Solveig van Nes, Barbara Grisdale-Helland, Ståle J. Helland and Bendik F. Terjesen

    Version of Record online : 5 JUN 2006, DOI: 10.1111/j.1742-4658.2006.05288.x

  10. You have free access to this content
    2012 American College of Rheumatology guidelines for management of gout. Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia

    Arthritis Care & Research

    Volume 64, Issue 10, October 2012, Pages: 1431–1446, Dinesh Khanna, John D. Fitzgerald, Puja P. Khanna, Sangmee Bae, Manjit K. Singh, Tuhina Neogi, Michael H. Pillinger, Joan Merill, Susan Lee, Shraddha Prakash, Marian Kaldas, Maneesh Gogia, Fernando Perez-Ruiz, Will Taylor, Frédéric Lioté, Hyon Choi, Jasvinder A. Singh, Nicola Dalbeth, Sanford Kaplan, Vandana Niyyar, Danielle Jones, Steven A. Yarows, Blake Roessler, Gail Kerr, Charles King, Gerald Levy, Daniel E. Furst, N. Lawrence Edwards, Brian Mandell, H. Ralph Schumacher, Mark Robbins, Neil Wenger and Robert Terkeltaub

    Version of Record online : 28 SEP 2012, DOI: 10.1002/acr.21772

  11. You have full text access to this OnlineOpen article
    Paracellular route is the major urate transport pathway across the blood-placental barrier

    Physiological Reports

    Volume 2, Issue 5, May 2014, Ichiro Uehara, Toru Kimura, Shinji Tanigaki, Toshiyuki Fukutomi, Keiji Sakai, Yoshihiko Shinohara, Kimiyoshi Ichida, Mitsutoshi Iwashita and Hiroyuki Sakurai

    Version of Record online : 20 MAY 2014, DOI: 10.14814/phy2.12013

  12. You have free access to this content
    Anti- and pro-oxidant effects of urate in copper-induced low-density lipoprotein oxidation

    European Journal of Biochemistry

    Volume 269, Issue 22, November 2002, Pages: 5474–5483, Paulo Filipe, Josiane Haigle, João Freitas, Afonso Fernandes, Jean-Claude Mazière, Cécile Mazière, René Santus and Patrice Morlière

    Version of Record online : 24 OCT 2002, DOI: 10.1046/j.1432-1033.2002.03245.x

  13. You have free access to this content
    A two-stage approach to the treatment of hyperuricemia in gout: The “dirty dish” hypothesis

    Arthritis & Rheumatism

    Volume 63, Issue 12, December 2011, Pages: 4002–4006, Fernando Perez-Ruiz, Ana Maria Herrero-Beites and Loreto Carmona

    Version of Record online : 29 NOV 2011, DOI: 10.1002/art.30649

  14. You have free access to this content
    Mendelian Randomization Analysis to Examine for a Causal Effect of Urate on Bone Mineral Density

    Journal of Bone and Mineral Research

    Volume 30, Issue 6, June 2015, Pages: 985–991, Nicola Dalbeth, Ruth Topless, Tanya Flynn, Murray Cadzow, Mark J Bolland and Tony R Merriman

    Version of Record online : 18 MAY 2015, DOI: 10.1002/jbmr.2434

  15. Vertebrate Renal System

    Standard Article

    Comprehensive Physiology

    Eldon J. Braun and William H. Dantzler

    Published Online : 1 JAN 2011, DOI: 10.1002/cphy.cp130108

  16. Molecular Genetics of Hyperuricaemia and Gout

    Standard Article


    Tony R Merriman and Tanya J Flynn

    Published Online : 18 OCT 2013, DOI: 10.1002/9780470015902.a0025153

  17. Gouty Arthritis: A Review of Acute Management and Prevention

    Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

    Volume 36, Issue 8, August 2016, Pages: 906–922, Liza Wilson and Joseph J. Saseen

    Version of Record online : 22 JUL 2016, DOI: 10.1002/phar.1788

  18. Antihyperuricemic and nephroprotective effects of resveratrol and its analogues in hyperuricemic mice

    Molecular Nutrition & Food Research

    Volume 56, Issue 9, September 2012, Pages: 1433–1444, Yun-Wei Shi, Cai-Ping Wang, Lei Liu, Yang-Liu Liu, Xing Wang, Ye Hong, Zhen Li and Ling-Dong Kong

    Version of Record online : 3 AUG 2012, DOI: 10.1002/mnfr.201100828

  19. You have free access to this content
    Reduction of plasma urate levels following treatment with multiple doses of pegloticase (polyethylene glycol–conjugated uricase) in patients with treatment-failure gout: Results of a phase II randomized study

    Arthritis & Rheumatism

    Volume 58, Issue 9, September 2008, Pages: 2882–2891, John S. Sundy, Michael A. Becker, Herbert S. B. Baraf, Andre Barkhuizen, Larry W. Moreland, William Huang, Royce W. Waltrip II, Allan N. Maroli, Zeb Horowitz and Pegloticase Phase 2 Study Investigators

    Version of Record online : 29 AUG 2008, DOI: 10.1002/art.23810

  20. You have free access to this content
    Using allopurinol above the dose based on creatinine clearance is effective and safe in patients with chronic gout, including those with renal impairment

    Arthritis & Rheumatism

    Volume 63, Issue 2, February 2011, Pages: 412–421, Lisa K. Stamp, John L. O'Donnell, Mei Zhang, Jill James, Christopher Frampton, Murray L. Barclay and Peter T. Chapman

    Version of Record online : 28 JAN 2011, DOI: 10.1002/art.30119