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There are 444 results for: content related to: Tofacitinib (CP-690,550) in patients with rheumatoid arthritis receiving methotrexate: Twelve-month data from a twenty-four–month phase III randomized radiographic study

  1. You have free access to this content
    Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs

    Arthritis & Rheumatism

    Volume 64, Issue 3, March 2012, Pages: 617–629, Roy Fleischmann, Maurizio Cutolo, Mark C. Genovese, Eun Bong Lee, Keith S. Kanik, Seth Sadis, Carol A. Connell, David Gruben, Sriram Krishnaswami, Gene Wallenstein, Bethanie E. Wilkinson and Samuel H. Zwillich

    Version of Record online : 28 FEB 2012, DOI: 10.1002/art.33383

  2. You have free access to this content
    A phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) versus placebo in combination with background methotrexate in patients with active rheumatoid arthritis and an inadequate response to methotrexate alone

    Arthritis & Rheumatism

    Volume 64, Issue 4, April 2012, Pages: 970–981, Joel M. Kremer, Stanley Cohen, Bethanie E. Wilkinson, Carol A. Connell, Jonathan L. French, Juan Gomez-Reino, David Gruben, Keith S. Kanik, Sriram Krishnaswami, Virginia Pascual-Ramos, Gene Wallenstein and Samuel H. Zwillich

    Version of Record online : 27 MAR 2012, DOI: 10.1002/art.33419

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    The JAK inhibitor tofacitinib regulates synovitis through inhibition of interferon-γ and interleukin-17 production by human CD4+ T cells

    Arthritis & Rheumatism

    Volume 64, Issue 6, June 2012, Pages: 1790–1798, Keisuke Maeshima, Kunihiro Yamaoka, Satoshi Kubo, Kazuhisa Nakano, Shigeru Iwata, Kazuyoshi Saito, Masanobu Ohishi, Hisaaki Miyahara, Shinya Tanaka, Koji Ishii, Hironobu Yoshimatsu and Yoshiya Tanaka

    Version of Record online : 25 MAY 2012, DOI: 10.1002/art.34329

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    Evaluation of the Effect of Tofacitinib Exposure on Outcomes in Kidney Transplant Patients

    American Journal of Transplantation

    Volume 15, Issue 6, June 2015, Pages: 1644–1653, F. Vincenti, H. T. Silva, S. Busque, P. J. O'Connell, G. Russ, K. Budde, A. Yoshida, M. A. Tortorici, M. Lamba, N. Lawendy, W. Wang and G. Chan

    Version of Record online : 3 FEB 2015, DOI: 10.1111/ajt.13181

  5. You have full text access to this OnlineOpen article
    Tofacitinib, an oral Janus kinase inhibitor, for the treatment of chronic plaque psoriasis: results from two randomized, placebo-controlled, phase III trials

    British Journal of Dermatology

    Volume 173, Issue 4, October 2015, Pages: 949–961, K.A. Papp, M.A. Menter, M. Abe, B. Elewski, S.R. Feldman, A.B. Gottlieb, R. Langley, T. Luger, D. Thaci, M. Buonanno, P. Gupta, J. Proulx, S. Lan, R. Wolk and for the OPT Pivotal 1 and OPT Pivotal 2 investigators

    Version of Record online : 29 OCT 2015, DOI: 10.1111/bjd.14018

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    Tofacitinib Facilitates the Expansion of Myeloid-Derived Suppressor Cells and Ameliorates Arthritis in SKG Mice

    Arthritis & Rheumatology

    Volume 67, Issue 4, April 2015, Pages: 893–902, Keisuke Nishimura, Jun Saegusa, Fumichika Matsuki, Kengo Akashi, Goichi Kageyama and Akio Morinobu

    Version of Record online : 27 MAR 2015, DOI: 10.1002/art.39007

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    Effects of Janus kinase inhibitor tofacitinib on circulating serum amyloid A and interleukin-6 during treatment for rheumatoid arthritis

    Clinical & Experimental Immunology

    Volume 175, Issue 2, February 2014, Pages: 208–214, K. Migita, Y. Izumi, Y. Jiuchi, H. Kozuru, C. Kawahara, M. Izumi, T. Sakai, M. Nakamura, S. Motokawa, T. Nakamura and A. Kawakami

    Version of Record online : 3 JAN 2014, DOI: 10.1111/cei.12234

  8. Tofacitinib withdrawal and retreatment in moderate-to-severe chronic plaque psoriasis: a randomized controlled trial

    British Journal of Dermatology

    Volume 172, Issue 5, May 2015, Pages: 1395–1406, R. Bissonnette, L. Iversen, H. Sofen, C.E.M. Griffiths, P. Foley, R. Romiti, M. Bachinsky, S.T. Rottinghaus, H. Tan, J. Proulx, H. Valdez, P. Gupta, L. Mallbris and R. Wolk

    Version of Record online : 2 APR 2015, DOI: 10.1111/bjd.13551

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    2016 ACR/ARHP Annual Meeting Abstract Supplement

    Arthritis & Rheumatology

    Volume 68, Issue S10, October 2016, Pages: 1–4550,

    Version of Record online : 8 NOV 2016, DOI: 10.1002/art.39977

  10. Biologic or tofacitinib monotherapy for rheumatoid arthritis in people with traditional disease-modifying anti-rheumatic drug (DMARD) failure: a Cochrane Systematic Review and network meta-analysis (NMA)

    Overview of Reviews

    The Cochrane Library

    Jasvinder A Singh, Alomgir Hossain, Elizabeth Tanjong Ghogomu, Amy S Mudano, Peter Tugwell and George A Wells

    Published Online : 17 NOV 2016, DOI: 10.1002/14651858.CD012437

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    2015 ACR/ARHP Annual Meeting Abstract Supplement

    Arthritis & Rheumatology

    Volume 67, Issue S10, October 2015, Pages: 1–4046,

    Version of Record online : 5 NOV 2015, DOI: 10.1002/art.39448

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    JAK inhibition with tofacitinib suppresses arthritic joint structural damage through decreased RANKL production

    Arthritis & Rheumatism

    Volume 64, Issue 11, November 2012, Pages: 3531–3542, Timothy P. LaBranche, Michael I. Jesson, Zaher A. Radi, Chad E. Storer, Julia A. Guzova, Sheri L. Bonar, Janice M. Thompson, Fernando A. Happa, Zachary S. Stewart, Yutian Zhan, Chris S. Bollinger, Prashant N. Bansal, Jeremy W. Wellen, Dean P. Wilkie, Steven A. Bailey, Peter T. Symanowicz, Martin Hegen, Richard D. Head, Nandini Kishore, Gabriel Mbalaviele and Debra M. Meyer

    Version of Record online : 27 OCT 2012, DOI: 10.1002/art.34649

  13. You have free access to this content
    Randomized Phase 2b Trial of Tofacitinib (CP-690,550) in De Novo Kidney Transplant Patients: Efficacy, Renal Function and Safety at 1 Year

    American Journal of Transplantation

    Volume 12, Issue 9, September 2012, Pages: 2446–2456, F. Vincenti, H. Tedesco Silva, S. Busque, P. O’Connell, J. Friedewald, D. Cibrik, K. Budde, A. Yoshida, S. Cohney, W. Weimar, Y. S. Kim, N. Lawendy, S.-P. Lan, E. Kudlacz, S. Krishnaswami and G. Chan

    Version of Record online : 8 JUN 2012, DOI: 10.1111/j.1600-6143.2012.04127.x

  14. Safety, tolerability, and pharmacokinetics of single oral doses of tofacitinib, a Janus kinase inhibitor, in healthy volunteers

    Clinical Pharmacology in Drug Development

    Volume 4, Issue 2, March/April 2015, Pages: 83–88, Sriram Krishnaswami, Mary Boy, Vincent Chow and Gary Chan

    Version of Record online : 5 DEC 2014, DOI: 10.1002/cpdd.171

  15. You have full text access to this OnlineOpen article
    Lack of effect of tofacitinib (CP-690,550) on the pharmacokinetics of the CYP3A4 substrate midazolam in healthy volunteers: confirmation of in vitro data

    British Journal of Clinical Pharmacology

    Volume 74, Issue 1, July 2012, Pages: 109–115, Pankaj Gupta, Christine Alvey, Rong Wang, Martin E. Dowty, Odette A. Fahmi, Robert L. Walsky, Richard J. Riese and Sriram Krishnaswami

    Version of Record online : 11 JUN 2012, DOI: 10.1111/j.1365-2125.2012.04168.x

  16. Biologics or tofacitinib for rheumatoid arthritis in incomplete responders to methotrexate or other traditional disease-modifying anti-rheumatic drugs: a systematic review and network meta-analysis

    Overview of Reviews

    The Cochrane Library

    Jasvinder A Singh, Alomgir Hossain, Elizabeth Tanjong Ghogomu, Ahmed Kotb, Robin Christensen, Amy S Mudano, Lara J Maxwell, Nipam P Shah, Peter Tugwell and George A Wells

    Published Online : 13 MAY 2016, DOI: 10.1002/14651858.CD012183

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    Phase II study of tofacitinib (CP-690,550) combined with methotrexate in patients with rheumatoid arthritis and an inadequate response to methotrexate

    Arthritis Care & Research

    Volume 63, Issue 8, August 2011, Pages: 1150–1158, Yoshiya Tanaka, Makoto Suzuki, Hiroyuki Nakamura, Shigeyuki Toyoizumi, Samuel H. Zwillich and Tofacitinib Study Investigators

    Version of Record online : 1 AUG 2011, DOI: 10.1002/acr.20494

  18. You have full text access to this OnlineOpen article
    Analysis of Infections and All-Cause Mortality in Phase II, Phase III, and Long-Term Extension Studies of Tofacitinib in Patients With Rheumatoid Arthritis

    Arthritis & Rheumatology

    Volume 66, Issue 11, November 2014, Pages: 2924–2937, Stanley Cohen, Sebastião C. Radominski, Juan J. Gomez-Reino, Lisy Wang, Sriram Krishnaswami, Susan P. Wood, Koshika Soma, Chudi I. Nduaka, Kenneth Kwok, Hernan Valdez, Birgitta Benda and Richard Riese

    Version of Record online : 26 OCT 2014, DOI: 10.1002/art.38779

  19. Efficacy and safety of tofacitinib, an oral Janus kinase inhibitor, in the treatment of psoriasis: a Phase 2b randomized placebo-controlled dose-ranging study

    British Journal of Dermatology

    Volume 167, Issue 3, September 2012, Pages: 668–677, K.A. Papp, A. Menter, B. Strober, R.G. Langley, M. Buonanno, R. Wolk, P. Gupta, S. Krishnaswami, H. Tan and J.A. Harness

    Version of Record online : 27 AUG 2012, DOI: 10.1111/j.1365-2133.2012.11168.x

  20. Biologics or tofacitinib for people with rheumatoid arthritis unsuccessfully treated with biologics: a systematic review and network meta-analysis

    Overview of Reviews

    The Cochrane Library

    Jasvinder A Singh, Alomgir Hossain, Elizabeth Tanjong Ghogomu, Amy S Mudano, Lara J Maxwell, Rachelle Buchbinder, Maria Angeles Lopez-Olivo, Maria E Suarez-Almazor, Peter Tugwell and George A Wells

    Published Online : 10 MAR 2017, DOI: 10.1002/14651858.CD012591