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There are 36881 results for: content related to: The two faces of FBW7 in cancer drug resistance

  1. You have free access to this content
    Tumor suppressor functions of FBW7 in cancer development and progression

    FEBS Letters

    Volume 586, Issue 10, May 21, 2012, Pages: 1409–1418, Zhiwei Wang, Hiroyuki Inuzuka, Jiateng Zhong, Lixin Wan, Hidefumi Fukushima, Fazlul H. Sarkar and Wenyi Wei

    Version of Record online : 21 MAR 2012, DOI: 10.1016/j.febslet.2012.03.017

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    Emerging roles of the FBW7 tumour suppressor in stem cell differentiation

    EMBO reports

    Volume 13, Issue 1, January 2012, Pages: 36–43, Zhiwei Wang, Hiroyuki Inuzuka, Hidefumi Fukushima, Lixin Wan, Daming Gao, Shavali Shaik, Fazlul H Sarkar and Wenyi Wei

    Version of Record online : 9 DEC 2011, DOI: 10.1038/embor.2011.231

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    PI3K-dependent phosphorylation of Fbw7 modulates substrate degradation and activity

    FEBS Letters

    Volume 585, Issue 14, July 21, 2011, Pages: 2151–2157, Christina Schülein, Martin Eilers and Nikita Popov

    Version of Record online : 24 MAY 2011, DOI: 10.1016/j.febslet.2011.05.036

  4. Cell cycle-dependent ubiquitylation and destruction of NDE1 by CDK5-FBW7 regulates ciliary length

    The EMBO Journal

    Volume 34, Issue 19, 1 October 2015, Pages: 2424–2440, Dipak Maskey, Matthew Caleb Marlin, Seokho Kim, Sehyun Kim, E-Ching Ong, Guangpu Li and Leonidas Tsiokas

    Version of Record online : 23 JUL 2015, DOI: 10.15252/embj.201490831

  5. Isoform-Specific SCFFbw7 Ubiquitination Mediates Differential Regulation of PGC-1α

    Journal of Cellular Physiology

    Volume 230, Issue 4, April 2015, Pages: 842–852, Julie S. Trausch-Azar, Mona Abed, Amir Orian and Alan L. Schwartz

    Version of Record online : 26 DEC 2014, DOI: 10.1002/jcp.24812

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    Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

    The EMBO Journal

    Volume 23, Issue 10, May 19, 2004, Pages: 2116–2125, Masayoshi Yada, Shigetsugu Hatakeyama, Takumi Kamura, Masaaki Nishiyama, Ryosuke Tsunematsu, Hiroyuki Imaki, Noriko Ishida, Fumihiko Okumura, Keiko Nakayama and Keiichi I Nakayama

    Version of Record online : 22 APR 2004, DOI: 10.1038/sj.emboj.7600217

  7. Ubiquitin-specific protease 22 (USP22) positively regulates RCAN1 protein levels through RCAN1 de-ubiquitination

    Journal of Cellular Physiology

    Volume 230, Issue 7, July 2015, Pages: 1651–1660, Ahyoung Hong, Ji Eun Lee and KWANG CHUL Chung

    Version of Record online : 27 MAR 2015, DOI: 10.1002/jcp.24917

  8. Negative regulation of HIF-1α by an FBW7-mediated degradation pathway during hypoxia

    Journal of Cellular Biochemistry

    Volume 112, Issue 12, December 2011, Pages: 3882–3890, Jessica M. Cassavaugh, Sarah A. Hale, Theresa L. Wellman, Alan K. Howe, Cheung Wong and Karen M. Lounsbury

    Version of Record online : 22 OCT 2011, DOI: 10.1002/jcb.23321

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    Novel mechanism by which histone deacetylase inhibitors facilitate topoisomerase IIα degradation in hepatocellular carcinoma cells


    Volume 53, Issue 1, January 2011, Pages: 148–159, Mei-Chuan Chen, Chun-Han Chen, Hsiao-Ching Chuang, Samuel K. Kulp, Che-Ming Teng and Ching-Shih Chen

    Version of Record online : 12 JAN 2011, DOI: 10.1002/hep.23964

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    Increased efficiency in the generation of induced pluripotent stem cells by Fbxw7 ablation

    Genes to Cells

    Volume 17, Issue 9, September 2012, Pages: 768–777, Yasutaka Okita, Akinobu Matsumoto, Kanae Yumimoto, Rieko Isoshita and Keiichi I. Nakayama

    Version of Record online : 16 AUG 2012, DOI: 10.1111/j.1365-2443.2012.01626.x

  11. The role of Fbxw7 expression in hepatocellular carcinoma and adjacent non-tumor liver tissue

    Journal of Gastroenterology and Hepatology

    Volume 29, Issue 10, October 2014, Pages: 1822–1829, Satoru Imura, Lkhagva-Ochir Tovuu, Tohru Utsunomiya, Yuji Morine, Tetsuya Ikemoto, Yusuke Arakawa, Mami Kanamoto, Shuichi Iwahashi, Yu Saito, Chie Takasu, Shinichiro Yamada, Daichi Ishikawa, Yoshimi Bando and Mitsuo Shimada

    Version of Record online : 15 OCT 2014, DOI: 10.1111/jgh.12623

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    FBXW7-mediated degradation of CCDC6 is impaired by ATM during DNA damage response in lung cancer cells

    FEBS Letters

    Volume 586, Issue 24, December 14, 2012, Pages: 4257–4263, Zhao JunGang, Tang Jun, Men WanFu and Ren KaiMing

    Version of Record online : 26 OCT 2012, DOI: 10.1016/j.febslet.2012.10.029

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    Stem cell and progenitor fate in the mammalian intestine: Notch and lateral inhibition in homeostasis and disease

    EMBO reports

    Volume 16, Issue 5, May 2015, Pages: 571–581, Rocio Sancho, Catherine A Cremona and Axel Behrens

    Version of Record online : 8 APR 2015, DOI: 10.15252/embr.201540188

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    Numb Regulates Glioma Stem Cell Fate and Growth by Altering Epidermal Growth Factor Receptor and Skp1-Cullin-F-Box Ubiquitin Ligase Activity


    Volume 30, Issue 7, July 2012, Pages: 1313–1326, Xiuli Jiang, Hongyan Xing, Tae-Min Kim, Yuchae Jung, Wei Huang, Hong Wei Yang, Shengye Song, Peter J. Park, Rona S. Carroll and Mark D. Johnson

    Version of Record online : 18 JUN 2012, DOI: 10.1002/stem.1120

  15. You have full text access to this OnlineOpen article
    FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development

    The Journal of Pathology

    Volume 224, Issue 2, June 2011, Pages: 180–189, Hayley Davis, Annabelle Lewis, Bradley Spencer-Dene, Hilda Tateossian, Gordon Stamp, Axel Behrens and Ian Tomlinson

    Version of Record online : 18 APR 2011, DOI: 10.1002/path.2874

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    The sensitivity of gastric cancer to trastuzumab is regulated by the miR-223/FBXW7 pathway

    International Journal of Cancer

    Volume 136, Issue 7, 1 April 2015, Pages: 1537–1545, Kojiro Eto, Masaaki Iwatsuki, Masayuki Watanabe, Takatsugu Ishimoto, Satoshi Ida, Yu Imamura, Shiro Iwagami, Yoshifumi Baba, Yasuo Sakamoto, Yuji Miyamoto, Naoya Yoshida and Hideo Baba

    Version of Record online : 11 SEP 2014, DOI: 10.1002/ijc.29168

  17. Pin1 promotes neuronal death in stroke by stabilizing Notch intracellular domain

    Annals of Neurology

    Volume 77, Issue 3, March 2015, Pages: 504–516, Sang-Ha Baik, Mitchell Fane, Joon Hyung Park, Yi-Lin Cheng, David Yang-Wei Fann, Ui Jeong Yun, Yuri Choi, Jong-Sung Park, Bing Han Chai, Jin Su Park, Seung Hyun Back, Jae In Jeong, Ye Jin Jang, Gahee Bahn, Joo-Yong Lee, Yu-I Li, Christopher G. Sobey, Takafumi Uchida, Jae Hyung Park, Hong Tae Kim, Sung-Chun Tang, Thiruma V. Arumugam and Dong-Gyu Jo

    Version of Record online : 3 FEB 2015, DOI: 10.1002/ana.24347

  18. You have full text access to this OnlineOpen article
    Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications

    EMBO Molecular Medicine

    Volume 4, Issue 7, July 2012, Pages: 545–556, Simone Fulda, Krishnaraj Rajalingam and Ivan Dikic

    Version of Record online : 25 JUN 2012, DOI: 10.1002/emmm.201100707

  19. Using a zebrafish Danio rerio model system to study NOTCH1-induced T-cell leukaemia

    Journal of Fish Biology

    Volume 73, Issue 5, October 2008, Pages: 1121–1138, J. Chen and J. D. Griffin

    Version of Record online : 7 OCT 2008, DOI: 10.1111/j.1095-8649.2008.01979.x

  20. Sorafenib induces endometrial carcinoma apoptosis by inhibiting Elk-1-dependent Mcl-1 transcription and inducing Akt/GSK3β-dependent protein degradation

    Journal of Cellular Biochemistry

    Volume 114, Issue 8, August 2013, Pages: 1819–1831, Nian-Kang Sun, Shang-Lang Huang, Ting-Chang Chang and Chuck C.-K. Chao

    Version of Record online : 11 JUN 2013, DOI: 10.1002/jcb.24530