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There are 11694 results for: content related to: Ca 2+ dysfunction in neurodegenerative disorders: Alzheimer's disease

  1. You have free access to this content
    Presenilin function and γ-secretase activity

    Journal of Neurochemistry

    Volume 93, Issue 4, May 2005, Pages: 769–792, A. L. Brunkan and A. M. Goate

    Article first published online : 1 APR 2005, DOI: 10.1111/j.1471-4159.2005.03099.x

  2. You have full text access to this Open Access content
    Calcium in the initiation, progression and as an effector of Alzheimer’s disease pathology

    Journal of Cellular and Molecular Medicine

    Volume 13, Issue 9a, September 2009, Pages: 2787–2799, Kim N. Green

    Article first published online : 24 JUL 2009, DOI: 10.1111/j.1582-4934.2009.00861.x

  3. β-Amyloid Therapeutic Strategies for Alzheimer's Disease

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    Burger's Medicinal Chemistry and Drug Discovery

    Bruno P. Imbimbo and Francesca Speroni

    Published Online : 14 OCT 2005, DOI: 10.1002/0471266949.bmc112

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    Intracellular calcium signalling in Alzheimer’s disease

    Journal of Cellular and Molecular Medicine

    Volume 14, Issue 1-2, January-February 2010, Pages: 30–41, Marina Hermes, Gerhard Eichhoff and Olga Garaschuk

    Article first published online : 19 NOV 2009, DOI: 10.1111/j.1582-4934.2009.00976.x

  5. Alzheimer's disease: Mechanisms and development of therapeutic strategies

    Geriatrics & Gerontology International

    Volume 3, Issue 4, December 2003, Pages: 175–188, Takeshi Tabira

    Article first published online : 8 DEC 2003, DOI: 10.1111/j.1444-1586.2003.00082.x

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    PEN-2 enhances γ-cleavage after presenilin heterodimer formation

    Journal of Neurochemistry

    Volume 90, Issue 6, September 2004, Pages: 1402–1413, Hirohisa Shiraishi, Xiaorei Sai, Hua-Qin Wang, Yasuhiro Maeda, Yukihisa Kurono, Masaki Nishimura, Katsuhiko Yanagisawa and Hiroto Komano

    Article first published online : 19 JUL 2004, DOI: 10.1111/j.1471-4159.2004.02597.x

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    FAD mutants unable to increase neurotoxic Aβ 42 suggest that mutation effects on neurodegeneration may be independent of effects on Aβ

    Journal of Neurochemistry

    Volume 101, Issue 3, May 2007, Pages: 674–681, Junichi Shioi, Anastasios Georgakopoulos, Pankaj Mehta, Zen Kouchi, Claudia M. Litterst, Lia Baki and Nikolaos K. Robakis

    Article first published online : 29 NOV 2006, DOI: 10.1111/j.1471-4159.2006.04391.x

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    Syntaxin 5 interacts specifically with presenilin holoproteins and affects processing of βAPP in neuronal cells

    Journal of Neurochemistry

    Volume 94, Issue 2, July 2005, Pages: 425–439, Kei Suga, Ayako Saito, Takami Tomiyama, Hiroshi Mori and Kimio Akagawa

    Article first published online : 10 JUN 2005, DOI: 10.1111/j.1471-4159.2005.03210.x

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    γ-secretase complexes containing caspase-cleaved presenilin-1 increase intracellular Aβ42/Aβ40 ratio

    Journal of Cellular and Molecular Medicine

    Volume 15, Issue 10, October 2011, Pages: 2150–2163, Louise Hedskog, Camilla A. Hansson Petersen, Annelie I. Svensson, Hedvig Welander, Lars O. Tjernberg, Helena Karlström and Maria Ankarcrona

    Article first published online : 26 SEP 2011, DOI: 10.1111/j.1582-4934.2010.01208.x

  10. Distinct presenilin-dependent and presenilin-independent γ-secretases are responsible for total cellular Aβ production

    Journal of Neuroscience Research

    Volume 74, Issue 3, 1 November 2003, Pages: 361–369, Christina A. Wilson, Robert W. Doms and Virginia M.-Y. Lee

    Article first published online : 28 OCT 2003, DOI: 10.1002/jnr.10776

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    Membrane Trafficking Pathways in Alzheimer's Disease

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    Volume 13, Issue 6, June 2012, Pages: 759–770, Lawrence Rajendran and Wim Annaert

    Article first published online : 17 FEB 2012, DOI: 10.1111/j.1600-0854.2012.01332.x

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    Proteolytic processing of Alzheimer’s β-amyloid precursor protein

    Journal of Neurochemistry

    Volume 120, Issue s1, January 2012, Pages: 9–21, Han Zhang, Qilin Ma, Yun-wu Zhang and Huaxi Xu

    Article first published online : 28 NOV 2011, DOI: 10.1111/j.1471-4159.2011.07519.x

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    Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in Aβ 42/40 ratios

    Journal of Neurochemistry

    Volume 92, Issue 2, January 2005, Pages: 294–301, Emily S. Walker, Maribel Martinez, Anne L. Brunkan and Alison Goate

    Article first published online : 9 DEC 2004, DOI: 10.1111/j.1471-4159.2004.02858.x

  14. You have full text access to this OnlineOpen article
    The mechanism of γ-Secretase dysfunction in familial Alzheimer disease

    The EMBO Journal

    Volume 31, Issue 10, May 16, 2012, Pages: 2261–2274, Lucía Chávez-Gutiérrez, Leen Bammens, Iryna Benilova, Annelies Vandersteen, Manasi Benurwar, Marianne Borgers, Sam Lismont, Lujia Zhou, Simon Van Cleynenbreugel, Hermann Esselmann, Jens Wiltfang, Lutgarde Serneels, Eric Karran, Harrie Gijsen, Joost Schymkowitz, Frederic Rousseau, Kerensa Broersen and Bart De Strooper

    Article first published online : 13 APR 2012, DOI: 10.1038/emboj.2012.79

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    The physiology of the β-amyloid precursor protein intracellular domain AICD

    Journal of Neurochemistry

    Volume 120, Issue s1, January 2012, Pages: 109–124, Raphaëlle Pardossi-Piquard and Frédéric Checler

    Article first published online : 28 NOV 2011, DOI: 10.1111/j.1471-4159.2011.07475.x

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    Presenilin endoproteolysis mediated by an aspartyl protease activity pharmacologically distinct from γ-secretase

    Journal of Neurochemistry

    Volume 85, Issue 6, June 2003, Pages: 1563–1574, William A. Campbell, Megan L. O. Reed, Jennifer Strahle, Michael S. Wolfe and Weiming Xia

    Article first published online : 13 MAY 2003, DOI: 10.1046/j.1471-4159.2003.01799.x

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    Cerebral amyloid angiopathy: pathogenetic mechanisms and link to dense amyloid plaques

    Genes, Brain and Behavior

    Volume 7, Issue s1, February 2008, Pages: 67–82, S. Kumar-Singh

    Article first published online : 3 JAN 2008, DOI: 10.1111/j.1601-183X.2007.00380.x

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    Genetic and molecular aspects of Alzheimer's disease shed light on new mechanisms of transcriptional regulation

    Genes, Brain and Behavior

    Volume 4, Issue 3, April 2005, Pages: 134–146, P. Marambaud and N. K. Robakis

    Article first published online : 1 APR 2005, DOI: 10.1111/j.1601-183X.2005.00086.x

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    Selecting cells with different Alzheimer's disease γ-secretase activity using FACS

    European Journal of Biochemistry

    Volume 270, Issue 3, February 2003, Pages: 495–506, M. Fleur Sernee, Geneviève Evin, Janetta G. Culvenor, José A. Villadangos, Konrad Beyreuther, Colin L. Masters and Roberto Cappai

    Article first published online : 13 JAN 2003, DOI: 10.1046/j.1432-1033.2003.03405.x

  20. Alzheimer's Disease

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    Reviews in Cell Biology and Molecular Medicine

    Jun Wang, Silva Hecimovic and Alison Goate

    Published Online : 15 SEP 2006, DOI: 10.1002/3527600906.mcb.200300078