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There are 30307 results for: content related to: Metabolic network modeling and simulation for drug targeting and discovery

  1. Flux-coupled genes and their use in metabolic flux analysis

    Biotechnology Journal

    Volume 8, Issue 9, September 2013, Pages: 1035–1042, Hyun Uk Kim, Won Jun Kim and Prof. Sang Yup Lee

    Version of Record online : 21 MAR 2013, DOI: 10.1002/biot.201200279

  2. Genome-scale modeling of human metabolism – a systems biology approach

    Biotechnology Journal

    Volume 8, Issue 9, September 2013, Pages: 985–996, Adil Mardinoglu, Francesco Gatto and Prof. Jens Nielsen

    Version of Record online : 24 APR 2013, DOI: 10.1002/biot.201200275

  3. Industrial Systems Biology

    Industrial Biotechnology: Sustainable Growth and Economic Success

    José Manuel Otero, Jens Nielsen, Pages: 79–147, 2010

    Published Online : 29 APR 2010, DOI: 10.1002/9783527630233.ch2

  4. You have free access to this content
    Using the reconstructed genome-scale human metabolic network to study physiology and pathology

    Journal of Internal Medicine

    Volume 271, Issue 2, February 2012, Pages: 131–141, A. Bordbar and B. O. Palsson

    Version of Record online : 17 JAN 2012, DOI: 10.1111/j.1365-2796.2011.02494.x

  5. Integration of Metabolic Knowledge for Genome-Scale Metabolic Reconstruction

    Biological Knowledge Discovery Handbook: Preprocessing, Mining, and Postprocessing of Biological Data

    Ali Masoudi-Nejad, Ali Salehzadeh-Yazdi, Shiva Akbari-Birgani, Yazdan Asgari, Pages: 1023–1048, 2013

    Published Online : 27 DEC 2013, DOI: 10.1002/9781118617151.ch45

  6. You have full text access to this OnlineOpen article
    Applications of genome-scale metabolic reconstructions

    Molecular Systems Biology

    Volume 5, Issue 1, 2009, Matthew A Oberhardt, Bernhard Ø Palsson and Jason A Papin

    Version of Record online : 3 NOV 2009, DOI: 10.1038/msb.2009.77

  7. Flux coupling and transcriptional regulation within the metabolic network of the photosynthetic bacterium Synechocystis sp. PCC6803

    Biotechnology Journal

    Volume 6, Issue 3, March 2011, Pages: 330–342, Arnau Montagud, Aleksej Zelezniak, Emilio Navarro, Pedro Fernández de Córdoba, Javier F. Urchueguía and Dr. Kiran Raosaheb Patil

    Version of Record online : 11 JAN 2011, DOI: 10.1002/biot.201000109

  8. Optimizing eukaryotic cell hosts for protein production through systems biotechnology and genome-scale modeling

    Biotechnology Journal

    Volume 10, Issue 7, July 2015, Pages: 939–949, Jahir M. Gutierrez and Nathan E. Lewis

    Version of Record online : 23 JUN 2015, DOI: 10.1002/biot.201400647

  9. You have full text access to this OnlineOpen article
    Basic and applied uses of genome-scale metabolic network reconstructions of Escherichia coli

    Molecular Systems Biology

    Volume 9, Issue 1, 2013, Douglas McCloskey, Bernhard Ø Palsson and Adam M Feist

    Version of Record online : 30 APR 2013, DOI: 10.1038/msb.2013.18

  10. Optimization-driven identification of genetic perturbations accelerates the convergence of model parameters in ensemble modeling of metabolic networks

    Biotechnology Journal

    Volume 8, Issue 9, September 2013, Pages: 1090–1104, Ali R. Zomorrodi, Jimmy G. Lafontaine Rivera, James C. Liao and Prof. Costas D. Maranas

    Version of Record online : 10 JUN 2013, DOI: 10.1002/biot.201200270

  11. Deriving metabolic engineering strategies from genome-scale modeling with flux ratio constraints

    Biotechnology Journal

    Volume 8, Issue 5, May 2013, Pages: 581–594, Jiun Y. Yen, Hadi Nazem-Bokaee, Benjamin G. Freedman, Ahmad I. M. Athamneh and Dr. Ryan S. Senger

    Version of Record online : 11 APR 2013, DOI: 10.1002/biot.201200234

  12. Towards kinetic modeling of genome-scale metabolic networks without sacrificing stoichiometric, thermodynamic and physiological constraints

    Biotechnology Journal

    Volume 8, Issue 9, September 2013, Pages: 1043–1057, Anirikh Chakrabarti, Ljubisa Miskovic, Keng Cher Soh and Prof. Vassily Hatzimanikatis

    Version of Record online : 20 AUG 2013, DOI: 10.1002/biot.201300091

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    Systems biology of host–microbe metabolomics

    Wiley Interdisciplinary Reviews: Systems Biology and Medicine

    Volume 7, Issue 4, July/August 2015, Pages: 195–219, Almut Heinken and Ines Thiele

    Version of Record online : 30 APR 2015, DOI: 10.1002/wsbm.1301

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    Software platforms to facilitate reconstructing genome-scale metabolic networks

    Environmental Microbiology

    Volume 16, Issue 1, January 2014, Pages: 49–59, Joshua J. Hamilton and Jennifer L. Reed

    Version of Record online : 18 NOV 2013, DOI: 10.1111/1462-2920.12312

  15. In Silico Genome-Scale Metabolic Models: The Constraint-Based Approach and Its Applications

    Systems Biology and Synthetic Biology

    Andrew R. Joyce, Bernhard Ø. Palsson, Pages: 193–233, 2009

    Published Online : 22 SEP 2009, DOI: 10.1002/9780470437988.ch6

  16. Metabolic network modeling of microbial communities

    Wiley Interdisciplinary Reviews: Systems Biology and Medicine

    Volume 7, Issue 5, September/October 2015, Pages: 317–334, Matthew B. Biggs, Gregory L. Medlock, Glynis L. Kolling and Jason A. Papin

    Version of Record online : 24 JUN 2015, DOI: 10.1002/wsbm.1308

  17. A reliable simulator for dynamic flux balance analysis

    Biotechnology and Bioengineering

    Volume 110, Issue 3, March 2013, Pages: 792–802, K. Höffner, S. M. Harwood and P. I. Barton

    Version of Record online : 18 OCT 2012, DOI: 10.1002/bit.24748

  18. Current trends in modeling host–pathogen interactions

    Wiley Interdisciplinary Reviews: Data Mining and Knowledge Discovery

    Volume 3, Issue 2, March/April 2013, Pages: 109–128, Sumanta Mukherjee, Awanti Sambarey, Karyala Prashanthi and Nagasuma Chandra

    Version of Record online : 25 FEB 2013, DOI: 10.1002/widm.1085

  19. The application of flux balance analysis in systems biology

    Wiley Interdisciplinary Reviews: Systems Biology and Medicine

    Volume 2, Issue 3, May/June 2010, Pages: 372–382, Erwin P. Gianchandani, Arvind K. Chavali and Jason A. Papin

    Version of Record online : 20 NOV 2009, DOI: 10.1002/wsbm.60

  20. Modeling with a view to target identification in metabolic engineering: A critical evaluation of the available tools

    Biotechnology Progress

    Volume 26, Issue 2, March/April 2010, Pages: 313–331, Jo Maertens and Peter A. Vanrolleghem

    Version of Record online : 5 JAN 2010, DOI: 10.1002/btpr.349