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There are 19453 results for: content related to: HDAC8 substrates: Histones and beyond

  1. Kinetics and thermodynamics of metal-binding to histone deacetylase 8

    Protein Science

    Volume 24, Issue 3, March 2015, Pages: 354–365, Byungchul Kim, Amit S. Pithadia and Carol A. Fierke

    Article first published online : 13 JAN 2015, DOI: 10.1002/pro.2623

  2. Towards Selective Inhibition of Histone Deacetylase Isoforms: What Has Been Achieved, Where We Are and What Will Be Next


    Volume 9, Issue 3, March 2014, Pages: 523–536, Dr. Florian Thaler and Dr. Ciro Mercurio

    Article first published online : 16 DEC 2013, DOI: 10.1002/cmdc.201300413

  3. Design, Synthesis, and Biological Activity of NCC149 Derivatives as Histone Deacetylase 8-Selective Inhibitors


    Volume 9, Issue 3, March 2014, Pages: 657–664, Prof. Takayoshi Suzuki, Nobusuke Muto, Dr. Masashige Bando, Dr. Yukihiro Itoh, Ayako Masaki, Dr. Masaki Ri, Yosuke Ota, Prof. Hidehiko Nakagawa, Prof. Shinsuke Iida, Prof. Katsuhiko Shirahige and Prof. Naoki Miyata

    Article first published online : 8 JAN 2014, DOI: 10.1002/cmdc.201300414

  4. Azetidinones as Zinc-Binding Groups to Design Selective HDAC8 Inhibitors


    Volume 4, Issue 12, December 7, 2009, Pages: 1991–2001, Paola Galletti, Arianna Quintavalla, Caterina Ventrici, Giuseppe Giannini, Walter Cabri, Sergio Penco, Grazia Gallo, Silvia Vincenti and Daria Giacomini

    Article first published online : 9 OCT 2009, DOI: 10.1002/cmdc.200900309

  5. Synthesis and Biological Evaluation of ortho-Aryl N-Hydroxycinnamides as Potent Histone Deacetylase (HDAC) 8 Isoform-Selective Inhibitors


    Volume 7, Issue 10, October 2012, Pages: 1815–1824, Dr. Wei-Jan Huang, Dr. Yi-Ching Wang, Shi-Wei Chao, Chen-Yui Yang, Liang-Chieh Chen, Dr. Mei-Hsiang Lin, Dr. Wen-Chi Hou, Mei-Yu Chen, Tai-Lin Lee, Ping Yang and Dr. Chung-I Chang

    Article first published online : 20 AUG 2012, DOI: 10.1002/cmdc.201200300

  6. Ligand release mechanisms and channels in histone deacetylases

    Journal of Computational Chemistry

    Volume 34, Issue 26, 5 October 2013, Pages: 2270–2283, Subha Kalyaanamoorthy and Yi-Ping Phoebe Chen

    Article first published online : 27 JUL 2013, DOI: 10.1002/jcc.23390

  7. You have full text access to this OnlineOpen article
    Using 15N-Ammonium to Characterise and Map Potassium Binding Sites in Proteins by NMR Spectroscopy


    Volume 15, Issue 4, March 3, 2014, Pages: 543–548, Dr. Nicolas D. Werbeck, Dr. John Kirkpatrick, Dr. Jochen Reinstein and Dr. D. Flemming Hansen

    Article first published online : 12 FEB 2014, DOI: 10.1002/cbic.201300700

  8. Thiol versus hydroxamate as zinc binding group in HDAC inhibition: An Ab initioQM/MM molecular dynamics study

    Journal of Computational Chemistry

    Volume 36, Issue 30, November 15, 2015, Pages: 2228–2235, Wenjing Gong, Ruibo Wu and Yingkai Zhang

    Article first published online : 9 OCT 2015, DOI: 10.1002/jcc.24203

  9. You have free access to this content
    The Chemical Tuning of a Weak Zinc Binding Motif for Histone Deacetylase Using Electronic Effects

    Chemical Biology & Drug Design

    Volume 80, Issue 2, August 2012, Pages: 203–214, Patrick McCarren, Michelle L. Hall and Lewis Whitehead

    Article first published online : 15 MAY 2012, DOI: 10.1111/j.1747-0285.2012.01382.x

  10. c-Abl induces stabilization of histone deacetylase 1 (HDAC1) in a kinase activity-dependent manner

    Cell Biology International

    Volume 39, Issue 4, April 2015, Pages: 446–456, Kazumasa Aoyama, Noritaka Yamaguchi, Ryuzaburo Yuki, Mariko Morii, Sho Kubota, Kensuke Hirata, Kohei Abe, Takuya Honda, Takahisa Kuga, Yuuki Hashimoto, Takeshi Tomonaga and Naoto Yamaguchi

    Article first published online : 5 JAN 2015, DOI: 10.1002/cbin.10413

  11. Phenotypic impact of deregulated expression of class I histone deacetylases in urothelial cell carcinoma of the bladder

    Molecular Carcinogenesis

    Volume 54, Issue 7, July 2015, Pages: 523–531, Susana Junqueira-Neto, Filipa Q. Vieira, Diana Montezuma, Natália R. Costa, Luís Antunes, Tiago Baptista, Ana Isabel Oliveira, Inês Graça, Ângelo Rodrigues, José S. Magalhães, Jorge Oliveira, Rui Henrique and Carmen Jerónimo

    Article first published online : 30 NOV 2013, DOI: 10.1002/mc.22117

  12. Highly Ligand Efficient and Selective N-2-(Thioethyl)picolinamide Histone Deacetylase Inhibitors Inspired by the Natural Product Psammaplin A


    Volume 8, Issue 1, January 2013, Pages: 149–156, Matthias G. J. Baud, Patricia Haus, Thomas Leiser, Prof. Dr. Franz-Josef Meyer-Almes and Dr. Matthew J. Fuchter

    Article first published online : 26 NOV 2012, DOI: 10.1002/cmdc.201200450

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    Multiple histone deacetylases repress tumor suppressor gene ARHI in breast cancer

    International Journal of Cancer

    Volume 120, Issue 8, 15 April 2007, Pages: 1664–1668, Weiwei Feng, Zhen Lu, Robert Z. Luo, Xiaohong Zhang, Edward Seto, Warren S.-L. Liao and Yinhua Yu

    Article first published online : 17 JAN 2007, DOI: 10.1002/ijc.22474

  14. Synthesis, Biological Evaluation, and Computer-Aided Drug Designing of New Derivatives of Hyperactive Suberoylanilide Hydroxamic Acid Histone Deacetylase Inhibitors

    Chemical Biology & Drug Design

    Volume 86, Issue 4, October 2015, Pages: 795–804, Song Zhang, Weibin Huang, Xiaonan Li, Zhicheng Yang and Binghong Feng

    Article first published online : 30 MAR 2015, DOI: 10.1111/cbdd.12554

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    Histone deacetylases: salesmen and customers in the post-translational modification market

    Biology of the Cell

    Volume 101, Issue 4, April 2009, Pages: 193–205, André Brandl, Thorsten Heinzel and Oliver H. Krämer

    Article first published online : 3 JAN 2012, DOI: 10.1042/BC20080158

  16. You have full text access to this OnlineOpen article
    The functional interactome landscape of the human histone deacetylase family

    Molecular Systems Biology

    Volume 9, Issue 1, 2013, Preeti Joshi, Todd M Greco, Amanda J Guise, Yang Luo, Fang Yu, Alexey I Nesvizhskii and Ileana M Cristea

    Article first published online : 11 JUN 2013, DOI: 10.1038/msb.2013.26

  17. You have free access to this content
    Epigenetic mechanisms regulate stage differentiation in the minimized protozoan Giardia lamblia

    Molecular Microbiology

    Volume 76, Issue 1, April 2010, Pages: 48–67, Sabrina Sonda, Laura Morf, Iveta Bottova, Hansruedi Baetschmann, Hubert Rehrauer, Amedeo Caflisch, Mohamed-Ali Hakimi and Adrian B. Hehl

    Article first published online : 1 FEB 2010, DOI: 10.1111/j.1365-2958.2010.07062.x

  18. Natural Products as Zinc-Dependent Histone Deacetylase Inhibitors


    Volume 10, Issue 3, March 2015, Pages: 441–450, Shuai Tan and Prof. Dr. Zhao-Peng Liu

    Article first published online : 7 JAN 2015, DOI: 10.1002/cmdc.201402460

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    HDAC11 is a novel drug target in carcinomas

    International Journal of Cancer

    Volume 132, Issue 9, 1 May 2013, Pages: 2200–2208, Hedwig E. Deubzer, Marie C. Schier, Ina Oehme, Marco Lodrini, Bernard Haendler, Anette Sommer and Olaf Witt

    Article first published online : 25 OCT 2012, DOI: 10.1002/ijc.27876

  20. Histone Acetylation and Deacetylation

    Standard Article

    Reviews in Cell Biology and Molecular Medicine

    Daniel M. Fass, Melissa M. Kemp, Frederick A. Schroeder, Florence F. Wagner, Qiu Wang and Edward B. Holson

    Published Online : 15 MAY 2012, DOI: 10.1002/3527600906.mcb.201100036