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There are 19014 results for: content related to: New insights into the roles of sulfated glycosaminoglycans in islet amyloid polypeptide amyloidogenesis and cytotoxicity

  1. Structural studies and cytotoxicity assays of “aggregation-prone” IAPP8–16 and its non-amyloidogenic variants suggest its important role in fibrillogenesis and cytotoxicity of human amylin

    Peptide Science

    Volume 104, Issue 3, May 2015, Pages: 196–205, Nikolaos N. Louros, Paraskevi L. Tsiolaki, Aikaterini A. Zompra, Eleni V. Pappa, Vassiliki Magafa, George Pairas, Paul Cordopatis, Christina Cheimonidou, Ioannis P. Trougakos, Vassiliki A. Iconomidou and Stavros J. Hamodrakas

    Version of Record online : 23 MAY 2015, DOI: 10.1002/bip.22650

  2. You have free access to this content
    Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process

    Protein Science

    Volume 18, Issue 7, July 2009, Pages: 1521–1530, Jed J. W. Wiltzius, Stuart A. Sievers, Michael R. Sawaya and David Eisenberg

    Version of Record online : 29 APR 2009, DOI: 10.1002/pro.145

  3. Dissecting the Role of Single Regions of an IAPP Mimic and IAPP in Inhibition of Aβ40 Amyloid Formation and Cytotoxicity

    ChemBioChem

    Volume 12, Issue 9, June 14, 2011, Pages: 1313–1322, Erika Andreetto, Dr. Li-Mei Yan, Dr. Andrea Caporale and Prof. Aphrodite Kapurniotu

    Version of Record online : 31 MAY 2011, DOI: 10.1002/cbic.201100192

  4. Metabolic stress, IAPP and islet amyloid

    Diabetes, Obesity and Metabolism

    Volume 14, Issue s3, October 2012, Pages: 68–77, J. Montane, A. Klimek-Abercrombie, K. J. Potter, C. Westwell-Roper and C. Bruce Verchere

    Version of Record online : 28 AUG 2012, DOI: 10.1111/j.1463-1326.2012.01657.x

  5. You have full text access to this OnlineOpen article
    Islet amyloid: From fundamental biophysics to mechanisms of cytotoxicity

    FEBS Letters

    Volume 587, Issue 8, April 17, 2013, Pages: 1106–1118, Ping Cao, Peter Marek, Harris Noor, Vadim Patsalo, Ling-Hsien Tu, Hui Wang, Andisheh Abedini and Daniel P. Raleigh

    Version of Record online : 1 FEB 2013, DOI: 10.1016/j.febslet.2013.01.046

  6. You have full text access to this OnlineOpen article
    Mechanisms of islet amyloidosis toxicity in type 2 diabetes

    FEBS Letters

    Volume 587, Issue 8, April 17, 2013, Pages: 1119–1127, Andisheh Abedini and Ann Marie Schmidt

    Version of Record online : 18 JAN 2013, DOI: 10.1016/j.febslet.2013.01.017

  7. Selectively N-Methylated Soluble IAPP Mimics as Potent IAPP Receptor Agonists and Nanomolar Inhibitors of Cytotoxic Self-Assembly of Both IAPP and Aβ40

    Angewandte Chemie International Edition

    Volume 52, Issue 39, September 23, 2013, Pages: 10378–10383, Dr. Li-Mei Yan, Dr. Aleksandra Velkova, Dipl.-Chem. Marianna Tatarek-Nossol, Prof. Dr. Gerhard Rammes, Dr. Andrei Sibaev, Dr. Erika Andreetto, Dipl.-Ing. Michael Kracklauer, Dipl.-Biochem. Maria Bakou, Dipl.-Chem. Eleni Malideli, Prof. Dr. Burkhard Göke, Prof. Dr. Jörg Schirra, Prof. Dr. Martin Storr and Prof. Dr. Aphrodite Kapurniotu

    Version of Record online : 19 AUG 2013, DOI: 10.1002/anie.201302840

  8. IAPP Mimic Blocks Aβ Cytotoxic Self-Assembly: Cross-Suppression of Amyloid Toxicity of Aβ and IAPP Suggests a Molecular Link between Alzheimer's Disease and Type II Diabetes

    Angewandte Chemie International Edition

    Volume 46, Issue 8, February 12, 2007, Pages: 1246–1252, Li-Mei Yan, Aleksandra Velkova, Marianna Tatarek-Nossol, Erika Andreetto and Aphrodite Kapurniotu

    Version of Record online : 4 JAN 2007, DOI: 10.1002/anie.200604056

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    Fluorescence microscopy studies on islet amyloid polypeptide fibrillation at heterogeneous and cellular membrane interfaces and its inhibition by resveratrol

    FEBS Letters

    Volume 583, Issue 9, May 06, 2009, Pages: 1439–1445, Diana Radovan, Norbert Opitz and Roland Winter

    Version of Record online : 1 APR 2009, DOI: 10.1016/j.febslet.2009.03.059

  10. Islet Amyloid Polypeptide/GLP-1/Exendin

    Standard Article

    International Textbook of Diabetes Mellitus

    Laurie L. Baggio and Daniel J. Drucker

    Published Online : 1 JUL 2003, DOI: 10.1002/0470862092.d0209

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    Amyloid Formation in Human Islets Is Enhanced by Heparin and Inhibited by Heparinase

    American Journal of Transplantation

    Volume 15, Issue 6, June 2015, Pages: 1519–1530, K. J. Potter, I. Werner, H. C. Denroche, J. Montane, A. Plesner, Y. Chen, D. Lei, G. Soukhatcheva, G. L. Warnock, J. Oberholzer, P. E. Fraser and C. B. Verchere

    Version of Record online : 1 APR 2015, DOI: 10.1111/ajt.13134

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    Interaction of membrane-bound islet amyloid polypeptide with soluble and crystalline insulin

    Protein Science

    Volume 17, Issue 10, October 2008, Pages: 1850–1856, Jefferson D. Knight, Jessica A. Williamson and Andrew D. Miranker

    Version of Record online : 2 JAN 2009, DOI: 10.1110/ps.036350.108

  13. Role of amino acid hydrophobicity, aromaticity, and molecular volume on IAPP(20–29) amyloid self-assembly

    Proteins: Structure, Function, and Bioinformatics

    Volume 80, Issue 4, April 2012, Pages: 1053–1065, Todd M. Doran, Alissa J. Kamens, Nadia K. Byrnes and Bradley L. Nilsson

    Version of Record online : 18 JAN 2012, DOI: 10.1002/prot.24007

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    Morin hydrate inhibits amyloid formation by islet amyloid polypeptide and disaggregates amyloid fibers

    Protein Science

    Volume 21, Issue 3, March 2012, Pages: 373–382, Harris Noor, Ping Cao and Daniel P. Raleigh

    Version of Record online : 31 JAN 2012, DOI: 10.1002/pro.2023

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    Inhibitors can arrest the membrane activity of human islet amyloid polypeptide independently of amyloid formation

    FEBS Letters

    Volume 507, Issue 2, October 26, 2001, Pages: 200–204, Thad A. Harroun, Jeremy P. Bradshaw and Richard H. Ashley

    Version of Record online : 18 OCT 2001, DOI: 10.1016/S0014-5793(01)02972-6

  16. The role of copper(II) and zinc(II) in the degradation of human and murine IAPP by insulin-degrading enzyme

    Journal of Mass Spectrometry

    Volume 49, Issue 4, April 2014, Pages: 274–279, Francesco Bellia and Giuseppe Grasso

    Version of Record online : 20 MAR 2014, DOI: 10.1002/jms.3338

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    Contribution of the intrinsic disulfide to the assembly mechanism of islet amyloid

    Protein Science

    Volume 14, Issue 1, January 2005, Pages: 231–239, Bon W. Koo and Andrew D. Miranker

    Version of Record online : 1 JAN 2009, DOI: 10.1110/ps.041051205

  18. You have full text access to this Open Access content
    Protective role of human insulin against the cytotoxicity associated with human mutant S20G islet amyloid polypeptide

    Journal of Diabetes Investigation

    Volume 4, Issue 5, September 2013, Pages: 436–444, Shuhei Morita, Minoru Ueyama, Setsuya Sakagashira, Yoshinori Shimajiri, Akiko Yamana, Machi Furuta and Tokio Sanke

    Version of Record online : 18 MAR 2013, DOI: 10.1111/jdi.12069

  19. Identification of Hot Regions of the Aβ–IAPP Interaction Interface as High-Affinity Binding Sites in both Cross- and Self-Association

    Angewandte Chemie International Edition

    Volume 49, Issue 17, April 12, 2010, Pages: 3081–3085, Erika Andreetto, Li-Mei Yan, Marianna Tatarek-Nossol, Aleksandra Velkova, Ronald Frank and Aphrodite Kapurniotu

    Version of Record online : 22 MAR 2010, DOI: 10.1002/anie.200904902

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    Direct detection of transient α-helical states in islet amyloid polypeptide

    Protein Science

    Volume 16, Issue 1, January 2007, Pages: 110–117, Jessica A. Williamson and Andrew D. Miranker

    Version of Record online : 1 JAN 2009, DOI: 10.1110/ps.062486907