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There are 18361 results for: content related to: Humanization of anti-human insulin receptor antibody for drug targeting across the human blood–brain barrier

  1. Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-γ-interferon antibody

    Journal of Molecular Recognition

    Volume 12, Issue 1, January/February 1999, Pages: 19–32, Zhao-chang Fan, Lin Shan, Benjamin Z. Goldsteen, Luke W. Guddat, Archana Thakur, Nicholas F. Landolfi, Man Sung Co, Maximiliano Vasquez, Cary Queen, Paul A. Ramsland and Allen B. Edmundson

    Version of Record online : 24 FEB 1999, DOI: 10.1002/(SICI)1099-1352(199901/02)12:1<19::AID-JMR445>3.0.CO;2-Y

  2. A universal combinatorial design of antibody framework to graft distinct CDR sequences: A bioinformatics approach

    Proteins: Structure, Function, and Bioinformatics

    Volume 80, Issue 3, March 2012, Pages: 896–912, Jaafar N. Haidar, Qing-An Yuan, Lin Zeng, Mark Snavely, Xenia Luna, Haifan Zhang, Wei Zhu, Dale L. Ludwig and Zhenping Zhu

    Version of Record online : 16 DEC 2011, DOI: 10.1002/prot.23246

    Corrected by:

    Errata: A universal combinatorial design of antibody framework to graft distinct CDR sequences: A bioinformatics approach

    Vol. 81, Issue 9, 1677, Version of Record online: 23 AUG 2013

  3. Mice as Clinically Relevant Models for the Study of Cytochrome P450-dependent Metabolism

    Clinical Pharmacology & Therapeutics

    Volume 83, Issue 6, June 2008, Pages: 818–828, S Muruganandan and CJ Sinal

    Version of Record online : 19 MAR 2008, DOI: 10.1038/clpt.2008.50

  4. Engineering Antibodies for Therapy

    Immunological Reviews

    Volume 130, Issue 1, December 1992, Pages: 5–40, John R. Adair

    Version of Record online : 28 APR 2006, DOI: 10.1111/j.1600-065X.1992.tb01519.x

  5. COMMODIFYING INDIGENEITY: HOW THE HUMANIZATION OF BIRTH REINFORCES RACIALIZED INEQUALITY IN MEXICO

    Medical Anthropology Quarterly

    Accepted manuscript online: 26 SEP 2016, Rosalynn Adeline Vega

    DOI: 10.1111/maq.12343

  6. A humanized monovalent CD3 antibody which can activate homologous complement

    European Journal of Immunology

    Volume 21, Issue 11, November 1991, Pages: 2717–2725, Edward G. Routledge, Irene Lloyd, Scott D. Gorman, Mike Clark and Herman Waldmann

    Version of Record online : 6 DEC 2005, DOI: 10.1002/eji.1830211111

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    Germline humanization of a murine Aβ antibody and crystal structure of the humanized recombinant Fab fragment

    Protein Science

    Volume 19, Issue 2, February 2010, Pages: 299–308, Remy Robert, Victor A. Streltsov, Janet Newman, Lesley A. Pearce, Kim L. Wark and Olan Dolezal

    Version of Record online : 15 DEC 2009, DOI: 10.1002/pro.312

  8. Expression and characterization of a humanized cocaine-binding antibody

    Biotechnology and Bioengineering

    Volume 82, Issue 5, 5 June 2003, Pages: 612–618, El-Rashdy M. Redwan, Nicholas A. Larsen, Bin Zhou, Peter Wirsching, Kim D. Janda and Ian A. Wilson

    Version of Record online : 13 MAR 2003, DOI: 10.1002/bit.10598

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    Restorative effect of hair follicular dermal cells on injured human hair follicles in a mouse model

    Experimental Dermatology

    Volume 24, Issue 3, March 2015, Pages: 225–227, Mikaru Yamao, Mutsumi Inamatsu, Taro Okada, Yuko Ogawa, Yuji Ishida, Chise Tateno and Katsutoshi Yoshizato

    Version of Record online : 26 FEB 2015, DOI: 10.1111/exd.12625

  10. Human CD4 and human major histocompatibility complex class II (DQ6) transgenic mice: supersensitivity to superantigen-induced septic shock

    European Journal of Immunology

    Volume 26, Issue 5, May 1996, Pages: 1074–1082, Rae S. M. Yeung, Josef M. Penninger, Thomas Kündig, Wilson Khoo, Pamela S. Ohashi, Guido Kroemer and Tak W. Mak

    Version of Record online : 5 DEC 2005, DOI: 10.1002/eji.1830260518

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    Construction and humanization of a functional bispecific EGFR × CD16 diabody using a refolding system

    The FEBS Journal

    Volume 279, Issue 2, January 2012, Pages: 223–233, Ryutaro Asano, Makoto Nakayama, Hiroko Kawaguchi, Tsuguo Kubota, Takeshi Nakanishi, Mitsuo Umetsu, Hiroki Hayashi, Yu Katayose, Michiaki Unno, Toshio Kudo and Izumi Kumagai

    Version of Record online : 6 DEC 2011, DOI: 10.1111/j.1742-4658.2011.08417.x

  12. Molecular Engineering I: Humanization

    Handbook of Therapeutic Antibodies

    Stefan Dübel, Pages: 119–144, 2008

    Published Online : 1 FEB 2008, DOI: 10.1002/9783527619740.ch6

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    Long-term human immune system reconstitution in non-obese diabetic (NOD)-Rag (–)-γ chain (–) (NRG) mice is similar but not identical to the original stem cell donor

    Clinical & Experimental Immunology

    Volume 174, Issue 3, December 2013, Pages: 402–413, D. T. Harris, M. Badowski, A. Balamurugan and O. O. Yang

    Version of Record online : 24 OCT 2013, DOI: 10.1111/cei.12192

  14. You have full text access to this Open Access content
    Mouse models with human immunity and their application in biomedical research

    Journal of Cellular and Molecular Medicine

    Volume 13, Issue 6, June 2009, Pages: 1043–1058, Baojun Zhang, Ziyuan Duan and Yong Zhao

    Version of Record online : 15 APR 2008, DOI: 10.1111/j.1582-4934.2008.00347.x

  15. Genetic engineering, expression, and activity of a fusion protein of a human neurotrophin and a molecular Trojan horse for delivery across the human blood–brain barrier

    Biotechnology and Bioengineering

    Volume 97, Issue 6, 15 August 2007, Pages: 1376–1386, Ruben J. Boado, Yufeng Zhang, Yun Zhang and William M. Pardridge

    Version of Record online : 7 FEB 2007, DOI: 10.1002/bit.21369

  16. Of mice and man: The lab mouse is being remodeled to better mimic how humans respond to disease

    Science News

    Volume 183, Issue 6, 23 March 2013, Pages: 22–25, Susan Gaidos

    Version of Record online : 15 MAR 2013, DOI: 10.1002/scin.5591830623

  17. The United States–Japan workshop on: The role of nuclear receptors in carcinogenesis

    Molecular Carcinogenesis

    Volume 41, Issue 2, October 2004, Pages: 77–84, Jeffrey M. Peters, Shigeaki Kato and Frank J. Gonzalez

    Version of Record online : 12 JUL 2004, DOI: 10.1002/mc.20040

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    Engraftment of peripheral blood mononuclear cells from systemic lupus erythematosus and antiphospholipid syndrome patient donors into BALB-RAG-2−/−IL-2Rγ−/− mice: A promising model for studying human disease

    Arthritis & Rheumatism

    Volume 63, Issue 9, September 2011, Pages: 2764–2773, Danieli Andrade, Patricia B. Redecha, Milena Vukelic, Xiaoping Qing, Giorgio Perino, Jane E. Salmon and Gloria C. Koo

    Version of Record online : 31 AUG 2011, DOI: 10.1002/art.30424

  19. GDNF fusion protein for targeted-drug delivery across the human blood–brain barrier

    Biotechnology and Bioengineering

    Volume 100, Issue 2, 1 June 2008, Pages: 387–396, Ruben J. Boado, Yun Zhang, Yufeng Zhang, Yuntao Wang and William M. Pardridge

    Version of Record online : 13 DEC 2007, DOI: 10.1002/bit.21764

  20. Nuclear Receptor-Mediated Gene Regulation in Drug Metabolism

    Drug Metabolism Handbook: Concepts and Applications

    Hongbing Wang, Wen Xie, Pages: 449–478, 2008

    Published Online : 4 AUG 2008, DOI: 10.1002/9780470439265.ch17