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There are 6600 results for: content related to: A novel system for evaluation of drug mixtures for potential efficacy in treating multidrug resistant cancers

  1. You have free access to this content
    Real-time fluorescence detection of multiple microscale cell culture analog devices in situ

    Cytometry Part A

    Volume 71A, Issue 10, October 2007, Pages: 857–865, Taek-il Oh, Jong Hwan Sung, Daniel A. Tatosian, Michael L. Shuler and Donghyun Kim

    Article first published online : 8 JUN 2007, DOI: 10.1002/cyto.a.20427

  2. Characterization of a gastrointestinal tract microscale cell culture analog used to predict drug toxicity

    Biotechnology and Bioengineering

    Volume 104, Issue 1, 1 September 2009, Pages: 193–205, Gretchen J. Mahler, Mandy B. Esch, Raymond P. Glahn and Michael L. Shuler

    Article first published online : 13 APR 2009, DOI: 10.1002/bit.22366

  3. PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically-based pharmacokinetic modeling approach

    Journal of Pharmaceutical Sciences

    Volume 100, Issue 10, October 2011, Pages: 4127–4157, Patrick Poulin, Rhys D. O. Jones, Hannah M. Jones, Christopher R. Gibson, Malcolm Rowland, Jenny Y. Chien, Barbara J. Ring, Kimberly K. Adkison, M. Sherry Ku, Handan He, Ragini Vuppugalla, Punit Marathe, Volker Fischer, Sandeep Dutta, Vikash K. Sinha, Thorir Björnsson, Thierry Lavé and James W. T. Yates

    Article first published online : 3 MAY 2011, DOI: 10.1002/jps.22550

  4. Physiologically Based Pharmacokinetic Modeling

    Preclinical Development Handbook: ADME and Biopharmaceutical Properties

    Harvey J. Clewell, Micaela B. Reddy, Thierry Lave, Melvin E. Andersen, Pages: 1167–1227, 2007

    Published Online : 27 AUG 2007, DOI: 10.1002/9780470249031.ch35

  5. Fluorescence optical detection in situ for real-time monitoring of cytochrome P450 enzymatic activity of liver cells in multiple microfluidic devices

    Biotechnology and Bioengineering

    Volume 104, Issue 3, 15 October 2009, Pages: 516–525, Jong Hwan Sung, Jong-ryul Choi, Donghyun Kim and Michael L. Shuler

    Article first published online : 20 MAY 2009, DOI: 10.1002/bit.22413

  6. A Distributed Parameter Physiologically-Based Pharmacokinetic Model for Dermal and Inhalation Exposure to Volatile Organic Compounds

    Risk Analysis

    Volume 16, Issue 2, April 1996, Pages: 147–160, A. Roy, C. P. Weisel, P. J. Lioy and P. G. Georgopoulos

    Article first published online : 15 JAN 2007, DOI: 10.1111/j.1539-6924.1996.tb01445.x

  7. Development of a Hybrid Physiologically Based Pharmacokinetic Model with Drug-Specific Scaling Factors in Rat to Improve Prediction of Human Pharmacokinetics

    Journal of Pharmaceutical Sciences

    Volume 102, Issue 11, November 2013, Pages: 4193–4204, Hiroyuki Sayama, Hiroshi Komura, Motohiro Kogayu and Masahiro Iwaki

    Article first published online : 9 SEP 2013, DOI: 10.1002/jps.23726

  8. Physiologically Based Pharmacokinetic Modeling

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    Pharmaceutical Sciences Encyclopedia

    Harvey J. Clewell, Micaela B. Reddy, Thierry Lave and Melvin E. Andersen

    Published Online : 15 MAR 2010, DOI: 10.1002/9780470571224.pse065

  9. Physiologically Based Pharmacokinetic Modeling: Inhalation, Ingestion, and Dermal Absorption

    Pharmacometrics: The Science of Quantitative Pharmacology

    Sastry S. Isukapalli, Amit Roy, Panos G. Georgopoulos, Pages: 1069–1106, 2006

    Published Online : 18 MAY 2006, DOI: 10.1002/9780470087978.ch43

  10. You have free access to this content
    Physiologically based pharmacokinetic (PBPK) modelling tools: how to fit with our needs?

    Biopharmaceutics & Drug Disposition

    Volume 33, Issue 2, March 2012, Pages: 55–71, François Bouzom, Kathryn Ball, Nathalie Perdaems and Bernard Walther

    Article first published online : 26 JAN 2012, DOI: 10.1002/bdd.1767

  11. Development of a Microscale Cell Culture Analog To Probe Naphthalene Toxicity

    Biotechnology Progress

    Volume 20, Issue 1, 2004, Pages: 316–323, Kwanchanok Viravaidya, Aaron Sin and Michael L. Shuler

    Article first published online : 5 SEP 2008, DOI: 10.1021/bp0341996

  12. Incorporation of 3T3-L1 Cells To Mimic Bioaccumulation in a Microscale Cell Culture Analog Device for Toxicity Studies

    Biotechnology Progress

    Volume 20, Issue 2, 2004, Pages: 590–597, Kwanchanok Viravaidya and Michael L. Shuler

    Article first published online : 5 SEP 2008, DOI: 10.1021/bp034238d

  13. Physiologically Based Pharmacokinetic (PBPK) Models in Cancer Risk Assessment

    Cancer Risk Assessment

    Mathieu Valcke, Kannan Krishnan, Pages: 557–585, 2010

    Published Online : 5 AUG 2010, DOI: 10.1002/9780470622728.ch21

  14. Evaluation of Exposure Change of Nonrenally Eliminated Drugs in Patients With Chronic Kidney Disease Using Physiologically Based Pharmacokinetic Modeling and Simulation

    The Journal of Clinical Pharmacology

    Volume 52, Issue S1, January 2012, Pages: 91S–108S, Dr Ping Zhao, Dr Manuela de L. T. Vieira, Dr Joseph A. Grillo, Dr Pengfei Song, Dr Ta-Chen Wu, Dr Jenny H. Zheng, Dr Vikram Arya, Dr Eva Gil Berglund, Dr Arthur J. Atkinson Jr, Dr Yuichi Sugiyama, Dr K. Sandy Pang, Dr Kellie S. Reynolds, Dr Darrell R. Abernethy, Dr Lei Zhang, Dr Lawrence J. Lesko and Dr Shiew-Mei Huang

    Article first published online : 23 APR 2013, DOI: 10.1177/0091270011415528

  15. Comparing translational population-PBPK modelling of brain microdialysis with bottom-up prediction of brain-to-plasma distribution in rat and human

    Biopharmaceutics & Drug Disposition

    Kathryn Ball, François Bouzom, Jean-Michel Scherrmann, Bernard Walther and Xavier Declèves

    Article first published online : 17 SEP 2014, DOI: 10.1002/bdd.1908

  16. Alkanes, Oxyhydrocarbons and Related Compounds

    Physiologically Based Pharmacokinetic Modeling: Science and Applications

    Robert T. Davidson, Micaela B. Reddy, Pages: 141–166, 2005

    Published Online : 27 JAN 2005, DOI: 10.1002/0471478768.ch6

  17. Physiologically Based Pharmacokinetic (PBPK) Modeling: Usefulness and Applications

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    Encyclopedia of Drug Metabolism and Interactions

    Han-Joo Maeng, Edwin C. Y. Chow, Jianghong Fan and K. Sandy Pang

    Published Online : 31 JAN 2012, DOI: 10.1002/9780470921920.edm036

  18. Co-culture with mesenchymal stem cells enhances metabolic functions of liver cells in bioartificial liver system

    Biotechnology and Bioengineering

    Volume 110, Issue 3, March 2013, Pages: 958–968, Ying Yang, Jianzhou Li, Xiaoping Pan, Pengcheng Zhou, Xiaopeng Yu, Hongcui Cao, Yingjie Wang and Lanjuan Li

    Article first published online : 1 NOV 2012, DOI: 10.1002/bit.24752

  19. Development and Application of Physiologically Based Pharmacokinetic-Modeling Tools to Support Drug Discovery

    Chemistry & Biodiversity

    Volume 2, Issue 11, November 2005, Pages: 1462–1486, Christian Lüpfert and Andreas Reichel

    Article first published online : 23 NOV 2005, DOI: 10.1002/cbdv.200590119

  20. Introduction: A Historical Perspective of the Development and Applications of PBPK Models

    Physiologically Based Pharmacokinetic Modeling: Science and Applications

    Melvin E. Andersen, Raymond S. H. Yang, Harvey J. Clewell, Micaela B. Reddy, Pages: 1–18, 2005

    Published Online : 27 JAN 2005, DOI: 10.1002/0471478768.ch1