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There are 15851 results for: content related to: Highly efficient deletion of FUT8 in CHO cell lines using zinc-finger nucleases yields cells that produce completely nonfucosylated antibodies

  1. Enhancement of DNA uptake in FUT8-deleted CHO cells for transient production of afucosylated antibodies

    Biotechnology and Bioengineering

    Volume 106, Issue 5, 1 August 2010, Pages: 751–763, Athena W. Wong, Tomasz K. Baginski and Dorothea E. Reilly

    Article first published online : 8 APR 2010, DOI: 10.1002/bit.22749

  2. Functional knockout of FUT8 in Chinese hamster ovary cells using CRISPR/Cas9 to produce a defucosylated antibody

    Engineering in Life Sciences

    Volume 15, Issue 6, September 2015, Pages: 660–666, Tao Sun, Chaodong Li, Lei Han, Hua Jiang, Yueqing Xie, Baohong Zhang, Xiuping Qian, Huili Lu and Jianwei Zhu

    Article first published online : 20 AUG 2015, DOI: 10.1002/elsc.201400218

  3. You have full text access to this OnlineOpen article
    Accelerating genome editing in CHO cells using CRISPR Cas9 and CRISPy, a web-based target finding tool

    Biotechnology and Bioengineering

    Volume 111, Issue 8, August 2014, Pages: 1604–1616, Carlotta Ronda, Lasse Ebdrup Pedersen, Henning Gram Hansen, Thomas Beuchert Kallehauge, Michael J. Betenbaugh, Alex Toftgaard Nielsen and Helene Faustrup Kildegaard

    Article first published online : 22 MAY 2014, DOI: 10.1002/bit.25233

  4. In vivo cleavage of transgene donors promotes nuclease-mediated targeted integration

    Biotechnology and Bioengineering

    Volume 110, Issue 3, March 2013, Pages: 871–880, Sandra Cristea, Yevgeniy Freyvert, Yolanda Santiago, Michael C. Holmes, Fyodor D. Urnov, Philip D. Gregory and Gregory J. Cost

    Article first published online : 23 OCT 2012, DOI: 10.1002/bit.24733

  5. Short-hairpin-RNA-mediated silencing of fucosyltransferase 8 in Chinese-hamster ovary cells for the production of antibodies with enhanced antibody immune effector function

    Biotechnology and Applied Biochemistry

    Volume 53, Issue 1, May 2009, Pages: 31–37, Vincent Beuger, Klaus-Peter Künkele, Hans Koll, Achim Gärtner, Monika Bähner, Helmut Burtscher and Christian Klein

    Article first published online : 23 DEC 2010, DOI: 10.1042/BA20080220

  6. One-step generation of triple knockout CHO cell lines using CRISPR/Cas9 and fluorescent enrichment

    Biotechnology Journal

    Volume 10, Issue 9, September 2015, Pages: 1446–1456, Lise Marie Grav, Jae Seong Lee, Signe Gerling, Thomas Beuchert Kallehauge, Anders Holmgaard Hansen, Stefan Kol, Gyun Min Lee, Lasse Ebdrup Pedersen and Helene Faustrup Kildegaard

    Article first published online : 30 APR 2015, DOI: 10.1002/biot.201500027

  7. Molecular and functional comparison of 1,25-dihydroxyvitamin D3 and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4

    Journal of Cellular Biochemistry

    Volume 94, Issue 5, 1 April 2005, Pages: 917–943, Peter W. Jurutka, Paul D. Thompson, G. Kerr Whitfield, Kristina R. Eichhorst, Neal Hall, Carlos Encinas Dominguez, Jui-Cheng Hsieh, Carol A. Haussler and Mark R. Haussler

    Article first published online : 2 DEC 2004, DOI: 10.1002/jcb.20359

  8. Phylogeography and biogeography of the lower Central American Neotropics: diversification between two continents and between two seas

    Biological Reviews

    Volume 89, Issue 4, November 2014, Pages: 767–790, Justin C. Bagley and Jerald B. Johnson

    Article first published online : 3 FEB 2014, DOI: 10.1111/brv.12076

  9. The Study of Laryngeal Muscle Activity in Normal Human Subjects and in Patients With Laryngeal Dystonia Using Multiple Fine-Wire Electromyography

    The Laryngoscope

    Volume 111, Issue S97, April 2001, Pages: 1–47, Allen D. Hillel

    Article first published online : 2 JAN 2009, DOI: 10.1097/00005537-200104001-00001

  10. Generation of a triple-gene knockout mammalian cell line using engineered zinc-finger nucleases

    Biotechnology and Bioengineering

    Volume 106, Issue 1, 1 May 2010, Pages: 97–105, Pei-Qi Liu, Edmond M. Chan, Gregory J. Cost, Lin Zhang, Jianbin Wang, Jeffrey C. Miller, Dmitry Y. Guschin, Andreas Reik, Michael C. Holmes, John E. Mott, Trevor N. Collingwood and Philip D. Gregory

    Article first published online : 31 DEC 2009, DOI: 10.1002/bit.22654

  11. Superhydrogels of Nanotubes Capable of Capturing Heavy-Metal Ions

    Chemistry – An Asian Journal

    Volume 9, Issue 1, January 2014, Pages: 245–252, Shasha Song, Haiqiao Wang, Dr. Aixin Song and Prof. Dr. Jingcheng Hao

    Article first published online : 18 OCT 2013, DOI: 10.1002/asia.201300892

  12. Use of Risk Assessment and Life Cycle Assessment in Decision Making: A Common Policy Research Agenda

    Risk Analysis

    Volume 22, Issue 5, October 2002, Pages: 879–894, Sarah J. Cowell, Robyn Fairman and Ragnar E. Lofstedt

    Article first published online : 2 SEP 2008, DOI: 10.1111/1539-6924.00258

  13. Integration of Life Cycle Assessment Into Agent-Based Modeling

    Journal of Industrial Ecology

    Volume 13, Issue 2, April 2009, Pages: 306–325, Chris Davis, Igor Nikolić and Gerard P. J. Dijkema

    Article first published online : 23 APR 2009, DOI: 10.1111/j.1530-9290.2009.00122.x

  14. You have full text access to this OnlineOpen article
    Who Cares About Life Cycle Assessment?

    Journal of Industrial Ecology

    Volume 18, Issue 6, December 2014, Pages: 787–791, Eric Masanet and Yuan Chang

    Article first published online : 7 OCT 2014, DOI: 10.1111/jiec.12189

  15. Environmental Life Cycle Assessment (LCA) of Energy Systems

    Standard Article

    Handbook of Clean Energy Systems

    Geoffrey P. Hammond, Craig I. Jones and Áine O'Grady

    Published Online : 16 JUL 2015, DOI: 10.1002/9781118991978.hces139

  16. Analyzing the Practice of Life Cycle Assessment

    Journal of Industrial Ecology

    Volume 17, Issue 5, October 2013, Pages: 777–788, Christi L. Saunders, Amy E. Landis, Laurel P. Mecca, Alex K. Jones, Laura A. Schaefer and Melissa M. Bilec

    Article first published online : 20 MAY 2013, DOI: 10.1111/jiec.12028

  17. Confronting Uncertainty in Life Cycle Assessment Used for Decision Support

    Journal of Industrial Ecology

    Volume 18, Issue 3, June 2014, Pages: 366–379, Ivan T. Herrmann, Michael Z. Hauschild, Michael D. Sohn and Thomas E. McKone

    Article first published online : 28 JAN 2014, DOI: 10.1111/jiec.12085

  18. Life Cycle Assessment

    Standard Article

    Kirk-Othmer Encyclopedia of Chemical Technology

    Jeroen B. Guinée and Reinout Heijungs

    Published Online : 18 MAR 2005, DOI: 10.1002/0471238961.lifeguin.a01

  19. Inactivation of GDP-fucose transporter gene (Slc35c1) in CHO cells by ZFNs, TALENs and CRISPR-Cas9 for production of fucose-free antibodies

    Biotechnology Journal

    Accepted manuscript online: 16 OCT 2015, Kah Fai Chan, Wahyu Shahreel, Corrine Wan, Gavin Teo, Noor Hayati, Shi Jie Tay, Wen Han Tong, Yuansheng Yang, Pauline M. Rudd, Peiqing Zhang and Zhiwei Song

    DOI: 10.1002/biot.201500331

  20. You have free access to this content
    Lithocholic acid disrupts phospholipid and sphingolipid homeostasis leading to cholestasis in mice


    Volume 53, Issue 4, April 2011, Pages: 1282–1293, Tsutomu Matsubara, Naoki Tanaka, Andrew D. Patterson, Joo-Youn Cho, Kristopher W. Krausz and Frank J. Gonzalez

    Article first published online : 7 APR 2011, DOI: 10.1002/hep.24193