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There are 60313 results for: content related to: A structured kinetic modeling framework for the dynamics of hybridoma growth and monoclonal antibody production in continuous suspension cultures

  1. A kinetic analysis of hybridoma growth and metabolism in batch and continuous suspension culture: Effect of nutrient concentration, dilution rate, and pH

    Biotechnology and Bioengineering

    Volume 32, Issue 8, 5 October 1988, Pages: 947–965, W. M. Miller, H. W. Blanch and C. R. Wilke

    Version of Record online : 18 FEB 2004, DOI: 10.1002/bit.260320803

  2. Kinetic analysis of hybridoma growth and monoclonal antibody production in semicontinuous culture

    Biotechnology and Bioengineering

    Volume 39, Issue 6, 15 March 1992, Pages: 596–606, M. Leno, O.-W. Merten and J. Hache

    Version of Record online : 19 FEB 2004, DOI: 10.1002/bit.260390603

  3. An Energetically Structured Model of Mammalian Cell Metabolism. 1. Model Development and Application to Steady-State Hybridoma Cell Growth in Continuous Culture

    Biotechnology Progress

    Volume 11, Issue 6, November/December 1995, Pages: 664–676, Don Dimasi and Randall W. Swartz

    Version of Record online : 5 SEP 2008, DOI: 10.1021/bp00036a010

  4. Cultivation of hybridoma cells in continuous cultures: Kinetics of growth and product formation

    Biotechnology and Bioengineering

    Volume 33, Issue 6, 5 February 1989, Pages: 724–730, N. G. Ray, S. B. Karkare and P. W. Runstadler Jr.

    Version of Record online : 18 FEB 2004, DOI: 10.1002/bit.260330610

  5. A kinetic analysis of hybridoma growth and metabolism in continuous suspension culture on serum-free medium

    Biotechnology and Bioengineering

    Volume 38, Issue 7, 5 October 1991, Pages: 733–741, G. W. Hiller, A. D. Aeschlimann, D. S. Clark and H. W. Blanch

    Version of Record online : 19 FEB 2004, DOI: 10.1002/bit.260380707

  6. Modified monoclonal antibody production kinetics kappa/gamma mRNA levels, and metabolic activities in a murine hybridoma selected by continuous Culture

    Biotechnology and Bioengineering

    Volume 44, Issue 6, 5 September 1994, Pages: 753–764, O.-W. Merten, D. Moeurs, H. Keller, M. Leno, G. E. Palfi, L . Cabanié and E. Couvé

    Version of Record online : 19 FEB 2004, DOI: 10.1002/bit.260440612

  7. Cell cycle model for growth rate and death rate in continuous suspension hybridoma cultures

    Biotechnology and Bioengineering

    Volume 40, Issue 3, July 1992, Pages: 359–368, Theodor I. Linardos, Nicolas Kalogerakis and Leo A. Behie

    Version of Record online : 19 FEB 2004, DOI: 10.1002/bit.260400305

  8. Effect of dilution rate on growth, productivity, cell cycle and size, and shear sensitivity of a hybridoma cell in a continuous culture

    Biotechnology and Bioengineering

    Volume 41, Issue 4, 20 February 1993, Pages: 429–439, D. E. Martens, C. D. de Gooijer, C. A. M. van der Velden-de Groot, E. C. Beuvery and J. Tramper

    Version of Record online : 19 FEB 2004, DOI: 10.1002/bit.260410406

  9. Monoclonal antibody production in dialyzed continuous suspension culture

    Biotechnology and Bioengineering

    Volume 39, Issue 5, 5 March 1992, Pages: 504–510, Theodor I. Linardos, Nicolas Kalogerakis, Leo A. Behie and Louis R. Lamontagne

    Version of Record online : 19 FEB 2004, DOI: 10.1002/bit.260390505

  10. Metabolic flux analysis of hybridoma continuous culture steady state multiplicity

    Biotechnology and Bioengineering

    Volume 63, Issue 6, 20 June 1999, Pages: 675–683, Brian D. Follstad, R. Robert Balcarcel, Gregory Stephanopoulos and Daniel I. C. Wang

    Version of Record online : 26 MAR 2000, DOI: 10.1002/(SICI)1097-0290(19990620)63:6<675::AID-BIT5>3.0.CO;2-R

  11. Bcl-2 over-expression reduces growth rate and prolongs G1 phase in continuous chemostat cultures of hybridoma cells

    Biotechnology and Bioengineering

    Volume 64, Issue 2, 20 July 1999, Pages: 174–186, N. H. Simpson, R. P. Singh, A. N. Emery and M. Al-Rubeai

    Version of Record online : 26 MAR 2000, DOI: 10.1002/(SICI)1097-0290(19990720)64:2<174::AID-BIT6>3.0.CO;2-D

  12. Unveiling steady-state multiplicity in hybridoma cultures: The cybernetic approach

    Biotechnology and Bioengineering

    Volume 81, Issue 1, 5 January 2003, Pages: 80–91, Abhijit Anand Namjoshi, Wei-Shou Hu and Doraiswami Ramkrishna

    Version of Record online : 12 NOV 2002, DOI: 10.1002/bit.10447

  13. Glycosylation of an immunoglobulin produced from a murine hybridoma cell line: The effect of culture mode and the anti-apoptotic gene, bcl-2

    Biotechnology and Bioengineering

    Volume 97, Issue 1, 1 May 2007, Pages: 156–169, F.A.A. Majid, M. Butler and M. Al-Rubeai

    Version of Record online : 29 SEP 2006, DOI: 10.1002/bit.21207

  14. Mechanism for multiplicity of steady states with distinct cell concentration in continuous culture of mammalian cells

    Biotechnology and Bioengineering

    Volume 112, Issue 7, July 2015, Pages: 1437–1445, Andrew Yongky, Jongchan Lee, Tung Le, Bhanu Chandra Mulukutla, Prodromos Daoutidis and Wei-Shou Hu

    Version of Record online : 13 MAR 2015, DOI: 10.1002/bit.25566

  15. Growth and production modeling in hybridoma continuous cultures

    Biotechnology and Bioengineering

    Volume 42, Issue 11, December 1993, Pages: 1322–1330, Lorenzo Cazzador and Luigi Mariani

    Version of Record online : 19 FEB 2004, DOI: 10.1002/bit.260421109

  16. Transition probability cell cycle model with product formation

    Biotechnology and Bioengineering

    Volume 58, Issue 4, 20 May 1998, Pages: 387–399, Scott J. Cain and Pao C. Chau

    Version of Record online : 26 MAR 2000, DOI: 10.1002/(SICI)1097-0290(19980520)58:4<387::AID-BIT6>3.0.CO;2-F

  17. Determinants and rate laws of growth and death of hybridoma cells in continuous culture

    Biotechnology and Bioengineering

    Volume 57, Issue 6, 20 March 1998, Pages: 642–654, An-Ping Zeng, Wolf-Dieter Deckwer and Wei-Shou Hu

    Version of Record online : 26 MAR 2000, DOI: 10.1002/(SICI)1097-0290(19980320)57:6<642::AID-BIT2>3.0.CO;2-L

  18. Mathematical modeling and analysis of monoclonal antibody production by hybridoma cells

    Biotechnology and Bioengineering

    Volume 50, Issue 3, 5 May 1996, Pages: 238–247, An-Ping Zeng

    Version of Record online : 26 MAR 2000, DOI: 10.1002/(SICI)1097-0290(19960505)50:3<238::AID-BIT2>3.0.CO;2-H

  19. Kinetic simulation of a centrifugal bioreactor for high population density hybridoma culture

    Biotechnology Progress

    Volume 25, Issue 6, November/December 2009, Pages: 1650–1659, Christopher J. Detzel, Derek J. Mason, William C. Davis and Bernard J. van Wie

    Version of Record online : 5 OCT 2009, DOI: 10.1002/btpr.240

  20. Mathematical modeling and analysis of glucose and glutamine utilization and regulation in cultures of continuous mammalian cells

    Biotechnology and Bioengineering

    Volume 47, Issue 3, 5 August 1995, Pages: 334–346, A.-P. Zeng and W.-D. Deckwer

    Version of Record online : 19 FEB 2004, DOI: 10.1002/bit.260470308