Search Results

There are 8621 results for: content related to: Structural Basis of Bcl-x L Recognition by a BH3-Mimetic α/β-Peptide Generated by Sequence-Based Design

  1. Bh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysis

    Proteins: Structure, Function, and Bioinformatics

    Volume 83, Issue 7, July 2015, Pages: 1262–1272, Sreekanth Rajan, Minjoo Choi, Kwanghee Baek and Ho Sup Yoon

    Version of Record online : 23 MAY 2015, DOI: 10.1002/prot.24816

  2. Structure-Guided Rational Design of α/β-Peptide Foldamers with High Affinity for BCL-2 Family Prosurvival Proteins


    Volume 14, Issue 13, September 2, 2013, Pages: 1564–1572, Prof. Brian J. Smith, Dr. Erinna F. Lee, James W. Checco, Marco Evangelista, Prof. Samuel H. Gellman and Dr. W. Douglas Fairlie

    Version of Record online : 8 AUG 2013, DOI: 10.1002/cbic.201300351

  3. You have free access to this content
    BH3-only proteins: The death-puppeteer's wires

    Cytometry Part A

    Volume 77A, Issue 1, January 2010, Pages: 11–21, Fabio Ghiotto, Franco Fais and Silvia Bruno

    Version of Record online : 6 NOV 2009, DOI: 10.1002/cyto.a.20819

  4. You have free access to this content
    Cell death and the mitochondria: therapeutic targeting of the BCL-2 family-driven pathway

    British Journal of Pharmacology

    Volume 171, Issue 8, April 2014, Pages: 1973–1987, M J Roy, A Vom, P E Czabotar and G Lessene

    Version of Record online : 28 MAR 2014, DOI: 10.1111/bph.12431

  5. Biophysical basis of the promiscuous binding of B-cell lymphoma protein 2 apoptotic repressor to BH3 ligands

    Journal of Molecular Recognition

    Volume 26, Issue 10, October 2013, Pages: 501–513, Vikas Bhat, Max B. Olenick, Brett J. Schuchardt, David C. Mikles, Caleb B. McDonald and Amjad Farooq

    Version of Record online : 29 AUG 2013, DOI: 10.1002/jmr.2295

  6. Anti-apoptotic Bcl-XL protein in complex with BH3 peptides of pro-apoptotic Bak, Bad, and Bim proteins: Comparative molecular dynamics simulations

    Proteins: Structure, Function, and Bioinformatics

    Volume 73, Issue 2, 1 November 2008, Pages: 492–514, Dilraj Lama and Ramasubbu Sankararamakrishnan

    Version of Record online : 1 MAY 2008, DOI: 10.1002/prot.22075

  7. You have free access to this content
    Bim–Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis

    Arthritis & Rheumatism

    Volume 62, Issue 2, February 2010, Pages: 441–451, John C. Scatizzi, Jack Hutcheson, Richard M. Pope, Gary S. Firestein, Alisa E. Koch, Melissa Mavers, Avraham Smason, Hemant Agrawal, G. Kenneth Haines III, Navdeep S. Chandel, Richard S. Hotchkiss and Harris Perlman

    Version of Record online : 28 JAN 2010, DOI: 10.1002/art.27198

  8. You have free access to this content
    BH3-in-groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes

    The EMBO Journal

    Volume 35, Issue 2, 18 January 2016, Pages: 208–236, Zhi Zhang, Sabareesh Subramaniam, Justin Kale, Chenyi Liao, Bo Huang, Hetal Brahmbhatt, Samson GF Condon, Suzanne M Lapolla, Franklin A Hays, Jingzhen Ding, Feng He, Xuejun C Zhang, Jianing Li, Alessandro Senes, David W Andrews and Jialing Lin

    Version of Record online : 23 DEC 2015, DOI: 10.15252/embj.201591552

  9. Apoptotic properties of the type 1 interferon induced family of human mitochondrial membrane ISG12 proteins

    Biology of the Cell

    Heidi Gytz, Mariann F. Hansen, Signe Skovbjerg, Anders C. M. Kristensen, Sofie Hørlyck, Mette B. Jensen, Marlene Fredborg, Lotte D. Markert, Nigel A. McMillan, Erik I. Christensen and Pia M. Martensen

    Version of Record online : 26 OCT 2016, DOI: 10.1111/boc.201600034

  10. You have free access to this content
    BH3-only proteins: a 20-year stock-take

    The FEBS Journal

    Volume 282, Issue 6, March 2015, Pages: 1006–1016, Marcel Doerflinger, Jason A. Glab and Hamsa Puthalakath

    Version of Record online : 26 JAN 2015, DOI: 10.1111/febs.13190

  11. You have free access to this content

    Clinical and Experimental Pharmacology and Physiology

    Volume 31, Issue 3, March 2004, Pages: 119–128, Shing-Leng Chan and Victor C Yu

    Version of Record online : 19 FEB 2004, DOI: 10.1111/j.1440-1681.2004.03975.x

  12. You have free access to this content
    Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein–protein recognition: Application to the Bim BH3 domain

    Protein Science

    Volume 17, Issue 7, July 2008, Pages: 1232–1240, Melissa D. Boersma, Jack D. Sadowsky, York A. Tomita and Samuel H. Gellman

    Version of Record online : 2 JAN 2009, DOI: 10.1110/ps.032896.107

  13. You have free access to this content
    Mcl-1–Bim complexes accommodate surprising point mutations via minor structural changes

    Protein Science

    Volume 19, Issue 3, March 2010, Pages: 507–519, Emiko Fire, Stefano V. Gullá, Robert A. Grant and Amy E. Keating

    Version of Record online : 11 JAN 2010, DOI: 10.1002/pro.329

  14. You have free access to this content
    Functional and physical interaction between Bcl-XL and a BH3-like domain in Beclin-1

    The EMBO Journal

    Volume 26, Issue 10, May 16, 2007, Pages: 2527–2539, M Chiara Maiuri, Gaëtane Le Toumelin, Alfredo Criollo, Jean-Christophe Rain, Fabien Gautier, Philippe Juin, Ezgi Tasdemir, Gérard Pierron, Kostoula Troulinaki, Nektarios Tavernarakis, John A Hickman, Olivier Geneste and Guido Kroemer

    Version of Record online : 19 APR 2007, DOI: 10.1038/sj.emboj.7601689

  15. Bcl-2 phosphorylation confers resistance on chronic lymphocytic leukaemia cells to the BH3 mimetics ABT-737, ABT-263 and ABT-199 by impeding direct binding

    British Journal of Pharmacology

    Volume 173, Issue 3, February 2016, Pages: 471–483, Ting Song, Gaobo Chai, Yubo Liu, Xiaoyan Yu, Ziqian Wang and Zhichao Zhang

    Version of Record online : 16 JAN 2016, DOI: 10.1111/bph.13370

  16. You have free access to this content
    A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis

    The EMBO Journal

    Volume 30, Issue 14, July 20, 2011, Pages: 2779–2792, Sabrina Büttner, Doris Ruli, F-Nora Vögtle, Lorenzo Galluzzi, Barbara Moitzi, Tobias Eisenberg, Oliver Kepp, Lukas Habernig, Didac Carmona-Gutierrez, Patrick Rockenfeller, Peter Laun, Michael Breitenbach, Chamel Khoury, Kai-Uwe Fröhlich, Gerald Rechberger, Chris Meisinger, Guido Kroemer and Frank Madeo

    Version of Record online : 14 JUN 2011, DOI: 10.1038/emboj.2011.197

  17. Human nuclear clusterin mediates apoptosis by interacting with Bcl-XL through C-terminal coiled coil domain

    Journal of Cellular Physiology

    Volume 227, Issue 3, March 2012, Pages: 1157–1167, Nayoung Kim, Jae Cheal Yoo, Jae Yoon Han, Eun Mi Hwang, Yoon Sook Kim, Eun Young Jeong, Choong-Hyun Sun, Gwan-Su Yi, Gu Seob Roh, Hyun Joon Kim, Sang Soo Kang, Gyeong Jae Cho, Jae-Yong Park and Wan Sung Choi

    Version of Record online : 22 DEC 2011, DOI: 10.1002/jcp.22836

  18. Discovery of a Small-Molecule pBcl-2 Inhibitor that Overcomes pBcl-2-Mediated Resistance to Apoptosis


    Volume 16, Issue 5, March 23, 2015, Pages: 757–765, Dr. Ting Song, Xiaoyan Yu, Dr. Yubo Liu, Dr. Xiangqian Li, Gaobo Chai and Dr. Zhichao Zhang

    Version of Record online : 25 FEB 2015, DOI: 10.1002/cbic.201402639

  19. You have free access to this content
    Discoveries and controversies in BCL-2 protein-mediated apoptosis

    The FEBS Journal

    Volume 283, Issue 14, July 2016, Pages: 2690–2700, Janet H. Zheng, Ariele Viacava Follis, Richard W. Kriwacki and Tudor Moldoveanu

    Version of Record online : 27 OCT 2015, DOI: 10.1111/febs.13527

  20. You have free access to this content
    BH3-only proteins: Integrated control point of apoptosis

    International Journal of Cancer

    Volume 119, Issue 9, 1 November 2006, Pages: 2036–2043, Tsukasa Shibue and Tadatsugu Taniguchi

    Version of Record online : 29 MAR 2006, DOI: 10.1002/ijc.21751