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There are 6940 results for: content related to: Structure-Guided Rational Design of α/β-Peptide Foldamers with High Affinity for BCL-2 Family Prosurvival Proteins

  1. You have free access to this content
    Phosphorylation of Mcl-1 by CDK1–cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest

    The EMBO Journal

    Volume 29, Issue 14, July 21, 2010, Pages: 2407–2420, Margaret E Harley, Lindsey A Allan, Helen S Sanderson and Paul R Clarke

    Article first published online : 4 JUN 2010, DOI: 10.1038/emboj.2010.112

  2. De Novo Design, Synthesis and Evaluation of Benzylpiperazine Derivatives as Highly Selective Binders of Mcl-1

    ChemMedChem

    Volume 8, Issue 12, December 2013, Pages: 1986–2014, Dr. Xiao Ding, Dr. Yan Li, Li Lv, Mi Zhou, Dr. Li Han, Zhengxi Zhang, Dr. Qian Ba, Dr. Jingquan Li, Prof. Hui Wang, Prof. Hong Liu and Prof. Renxiao Wang

    Article first published online : 9 OCT 2013, DOI: 10.1002/cmdc.201300316

  3. A novel BH3 mimetic efficiently induces apoptosis in melanoma cells through direct binding to anti-apoptotic Bcl-2 family proteins, including phosphorylated Mcl-1

    Pigment Cell & Melanoma Research

    Volume 28, Issue 2, March 2015, Pages: 161–170, Yubo Liu, Mingzhou Xie, Ting Song, Hongkun Sheng, Xiaoyan Yu and Zhichao Zhang

    Article first published online : 18 DEC 2014, DOI: 10.1111/pcmr.12325

  4. Acoustic overstimulation modifies Mcl-1 expression in cochlear sensory epithelial cells

    Journal of Neuroscience Research

    Volume 88, Issue 8, June 2010, Pages: 1812–1821, Bo Hua Hu and Qunfeng Cai

    Article first published online : 20 JAN 2010, DOI: 10.1002/jnr.22333

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    Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver

    Hepatology

    Volume 50, Issue 4, October 2009, Pages: 1217–1226, Hayato Hikita, Tetsuo Takehara, Satoshi Shimizu, Takahiro Kodama, Wei Li, Takuya Miyagi, Atsushi Hosui, Hisashi Ishida, Kazuyoshi Ohkawa, Tatsuya Kanto, Naoki Hiramatsu, Xiao-Ming Yin, Lothar Hennighausen, Tomohide Tatsumi and Norio Hayashi

    Article first published online : 15 JUN 2009, DOI: 10.1002/hep.23126

  6. Through a glass less darkly: apoptosis and the germinal center response to antigen

    Immunological Reviews

    Volume 247, Issue 1, May 2012, Pages: 93–106, Victor Peperzak, Ingela B. Vikstrom and David M. Tarlinton

    Article first published online : 13 APR 2012, DOI: 10.1111/j.1600-065X.2012.01123.x

  7. Sorafenib induces endometrial carcinoma apoptosis by inhibiting Elk-1-dependent Mcl-1 transcription and inducing Akt/GSK3β-dependent protein degradation

    Journal of Cellular Biochemistry

    Volume 114, Issue 8, August 2013, Pages: 1819–1831, Nian-Kang Sun, Shang-Lang Huang, Ting-Chang Chang and Chuck C.-K. Chao

    Article first published online : 11 JUN 2013, DOI: 10.1002/jcb.24530

  8. You have free access to this content
    Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes

    Hepatology

    Volume 49, Issue 2, February 2009, Pages: 627–636, Binje Vick, Achim Weber, Toni Urbanik, Thorsten Maass, Andreas Teufel, Peter H. Krammer, Joseph T. Opferman, Marcus Schuchmann, Peter R. Galle and Henning Schulze-Bergkamen

    Article first published online : 19 NOV 2008, DOI: 10.1002/hep.22664

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    Hepatocyte-specific deletion of the antiapoptotic protein myeloid cell leukemia-1 triggers proliferation and hepatocarcinogenesis in mice

    Hepatology

    Volume 51, Issue 4, April 2010, Pages: 1226–1236, Achim Weber, Regina Boger, Binje Vick, Toni Urbanik, Johannes Haybaeck, Stefan Zoller, Andreas Teufel, Peter H. Krammer, Joseph T. Opferman, Peter R. Galle, Marcus Schuchmann, Mathias Heikenwalder and Henning Schulze-Bergkamen

    Article first published online : 30 NOV 2009, DOI: 10.1002/hep.23479

  10. IL-15 regulates Bcl-2 family members Bim and Mcl-1 through JAK/STAT and PI3K/AKT pathways in T cells

    European Journal of Immunology

    Volume 44, Issue 8, August 2014, Pages: 2500–2507, Aparna R. Shenoy, Susanne Kirschnek and Georg Häcker

    Article first published online : 10 JUN 2014, DOI: 10.1002/eji.201344238

  11. Patterns and traits of the endemic plants of Greece

    Botanical Journal of the Linnean Society

    Volume 162, Issue 2, February 2010, Pages: 130–422, KYRIACOS GEORGHIOU and PINELOPI DELIPETROU

    Article first published online : 27 JAN 2010, DOI: 10.1111/j.1095-8339.2010.01025.x

  12. Synthesis and structure–activity investigation of novel vasopressin hypotensive peptide agonists

    Journal of Peptide Science

    Volume 5, Issue 11, November 1999, Pages: 472–490, Maurice Manning, Stoytcho Stoev, Ling Ling Cheng, Nga Ching Wo and W.Y. Chan

    Article first published online : 9 NOV 1999, DOI: 10.1002/(SICI)1099-1387(199911)5:11<472::AID-PSC217>3.0.CO;2-A

  13. You have full text access to this Open Access content
    Increased MCL–1 Expression Is Associated with Poor Prognosis in Ovarian Carcinomas

    Japanese Journal of Cancer Research

    Volume 93, Issue 5, May 2002, Pages: 542–550, Kazushi Shigemasa, Osamu Katoh, Yuko Shiroyama, Shoji Mihara, Keiji Mukai, Nobutaka Nagai and Koso Ohama

    Article first published online : 30 AUG 2005, DOI: 10.1111/j.1349-7006.2002.tb01289.x

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    Mcl-1–Bim complexes accommodate surprising point mutations via minor structural changes

    Protein Science

    Volume 19, Issue 3, March 2010, Pages: 507–519, Emiko Fire, Stefano V. Gullá, Robert A. Grant and Amy E. Keating

    Article first published online : 11 JAN 2010, DOI: 10.1002/pro.329

  15. Expression of Mcl-1 in mantle cell lymphoma is associated with high-grade morphology, a high proliferative state, and p53 overexpression

    The Journal of Pathology

    Volume 199, Issue 1, January 2003, Pages: 90–97, Joseph D Khoury, L Jeffrey Medeiros, George Z Rassidakis, Timothy J McDonnell, Lynne V Abruzzo and Raymond Lai

    Article first published online : 29 NOV 2002, DOI: 10.1002/path.1254

  16. Human oral cancers have altered expression of Bcl-2 family members and increased expression of the anti-apoptotic splice variant of Mcl-1

    The Journal of Pathology

    Volume 217, Issue 3, February 2009, Pages: 398–407, S Mallick, R Patil, R Gyanchandani, S Pawar, V Palve, S Kannan, KA Pathak, M Choudhary and TR Teni

    Article first published online : 30 SEP 2008, DOI: 10.1002/path.2459

  17. Convallaria keiskei as a novel therapeutic alternative for salivary gland cancer treatment by targeting myeloid cell leukemia-1

    Head & Neck

    Haeng-Eun Lee, Jeong-Seok Nam, Ji-Ae Shin, In-Sun Hong, In-Hyoung Yang, Myung-Jo You and Sung-Dae Cho

    Article first published online : 15 JUL 2015, DOI: 10.1002/hed.24096

  18. Overexpression of anti-apoptotic Mcl-1 in testicular germ cell tumours

    Histopathology

    Volume 46, Issue 5, May 2005, Pages: 532–539, M Sano, Y Nakanishi, H Yagasaki, T Honma, T Oinuma, Y Obana, A Suzuki and N Nemoto

    Article first published online : 17 MAR 2005, DOI: 10.1111/j.1365-2559.2005.02118.x

  19. You have free access to this content
    MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner

    The EMBO Journal

    Volume 30, Issue 2, January 19, 2011, Pages: 395–407, Marc Germain, Angela P Nguyen, J Nicole Le Grand, Nicole Arbour, Jacqueline L Vanderluit, David S Park, Joseph T Opferman and Ruth S Slack

    Article first published online : 7 DEC 2010, DOI: 10.1038/emboj.2010.327

  20. Increased expression of Mcl-1 is responsible for the blockage of TRAIL-induced apoptosis mediated by EGF/ErbB1 signaling pathway

    Journal of Cellular Biochemistry

    Volume 89, Issue 6, 15 August 2003, Pages: 1177–1192, Elizabeth S. Henson, Erika M. Gibson, Jacylyn Villanueva, Nicolle A. Bristow, Neil Haney and Spencer B. Gibson

    Article first published online : 1 JUL 2003, DOI: 10.1002/jcb.10597