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There are 13988 results for: content related to: Multivalent Design of Apoptosis-Inducing Bid-BH3 Peptide–Oligosaccharides Boosts the Intracellular Activity at Identical Overall Peptide Concentrations

  1. Bh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysis

    Proteins: Structure, Function, and Bioinformatics

    Sreekanth Rajan, Minjoo Choi, Kwanghee Baek and Ho Sup Yoon

    Article first published online : 23 MAY 2015, DOI: 10.1002/prot.24816

  2. Biophysical basis of the promiscuous binding of B-cell lymphoma protein 2 apoptotic repressor to BH3 ligands

    Journal of Molecular Recognition

    Volume 26, Issue 10, October 2013, Pages: 501–513, Vikas Bhat, Max B. Olenick, Brett J. Schuchardt, David C. Mikles, Caleb B. McDonald and Amjad Farooq

    Article first published online : 29 AUG 2013, DOI: 10.1002/jmr.2295

  3. Anti-apoptotic Bcl-XL protein in complex with BH3 peptides of pro-apoptotic Bak, Bad, and Bim proteins: Comparative molecular dynamics simulations

    Proteins: Structure, Function, and Bioinformatics

    Volume 73, Issue 2, 1 November 2008, Pages: 492–514, Dilraj Lama and Ramasubbu Sankararamakrishnan

    Article first published online : 1 MAY 2008, DOI: 10.1002/prot.22075

  4. Stabilization of Peptides for Intracellular Applications by Phosphoramidate-Linked Polyethylene Glycol Chains

    Angewandte Chemie International Edition

    Volume 52, Issue 45, November 4, 2013, Pages: 11920–11924, Nicole Nischan, Alokta Chakrabarti, Remigiusz A. Serwa, Petra H. M. Bovee-Geurts, Prof. Roland Brock and Prof. Christian P. R. Hackenberger

    Article first published online : 22 AUG 2013, DOI: 10.1002/anie.201303467

  5. Molecular determinants of the binding specificity of BH3 ligands to BclXL apoptotic repressor

    Biopolymers

    Volume 101, Issue 6, June 2014, Pages: 573–582, Vikas Bhat, Max B. Olenick, Brett J. Schuchardt, David C. Mikles, Caleb B. McDonald and Amjad Farooq

    Article first published online : 25 MAR 2014, DOI: 10.1002/bip.22419

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    Cell death and the mitochondria: therapeutic targeting of the BCL-2 family-driven pathway

    British Journal of Pharmacology

    Volume 171, Issue 8, April 2014, Pages: 1973–1987, M J Roy, A Vom, P E Czabotar and G Lessene

    Article first published online : 28 MAR 2014, DOI: 10.1111/bph.12431

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    Mcl-1–Bim complexes accommodate surprising point mutations via minor structural changes

    Protein Science

    Volume 19, Issue 3, March 2010, Pages: 507–519, Emiko Fire, Stefano V. Gullá, Robert A. Grant and Amy E. Keating

    Article first published online : 11 JAN 2010, DOI: 10.1002/pro.329

  8. Discovery of a Small-Molecule pBcl-2 Inhibitor that Overcomes pBcl-2-Mediated Resistance to Apoptosis

    ChemBioChem

    Volume 16, Issue 5, March 23, 2015, Pages: 757–765, Dr. Ting Song, Xiaoyan Yu, Dr. Yubo Liu, Dr. Xiangqian Li, Gaobo Chai and Dr. Zhichao Zhang

    Article first published online : 25 FEB 2015, DOI: 10.1002/cbic.201402639

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    Bim–Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis

    Arthritis & Rheumatism

    Volume 62, Issue 2, February 2010, Pages: 441–451, John C. Scatizzi, Jack Hutcheson, Richard M. Pope, Gary S. Firestein, Alisa E. Koch, Melissa Mavers, Avraham Smason, Hemant Agrawal, G. Kenneth Haines III, Navdeep S. Chandel, Richard S. Hotchkiss and Harris Perlman

    Article first published online : 28 JAN 2010, DOI: 10.1002/art.27198

  10. Structure-Guided Rational Design of α/β-Peptide Foldamers with High Affinity for BCL-2 Family Prosurvival Proteins

    ChemBioChem

    Volume 14, Issue 13, September 2, 2013, Pages: 1564–1572, Prof. Brian J. Smith, Dr. Erinna F. Lee, James W. Checco, Marco Evangelista, Prof. Samuel H. Gellman and Dr. W. Douglas Fairlie

    Article first published online : 8 AUG 2013, DOI: 10.1002/cbic.201300351

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    Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein–protein recognition: Application to the Bim BH3 domain

    Protein Science

    Volume 17, Issue 7, July 2008, Pages: 1232–1240, Melissa D. Boersma, Jack D. Sadowsky, York A. Tomita and Samuel H. Gellman

    Article first published online : 2 JAN 2009, DOI: 10.1110/ps.032896.107

  12. Nuclear Magnetic Resonance study of protein–protein interactions involving apoptosis regulator Diva (Boo) and the BH3 domain of proapoptotic Bcl-2 members

    Journal of Molecular Recognition

    Volume 25, Issue 12, December 2012, Pages: 665–673, Clara M. Santiveri, Lorenzo Sborgi and Eva de Alba

    Article first published online : 21 NOV 2012, DOI: 10.1002/jmr.2240

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    Functional and physical interaction between Bcl-XL and a BH3-like domain in Beclin-1

    The EMBO Journal

    Volume 26, Issue 10, May 16, 2007, Pages: 2527–2539, M Chiara Maiuri, Gaëtane Le Toumelin, Alfredo Criollo, Jean-Christophe Rain, Fabien Gautier, Philippe Juin, Ezgi Tasdemir, Gérard Pierron, Kostoula Troulinaki, Nektarios Tavernarakis, John A Hickman, Olivier Geneste and Guido Kroemer

    Article first published online : 19 APR 2007, DOI: 10.1038/sj.emboj.7601689

  14. BAK

    Standard Article

    Encyclopedia of Inorganic and Bioinorganic Chemistry

    Tudor Moldoveanu, Qian Liu, Douglas R Green and Kalle Gehring

    Published Online : 15 DEC 2011, DOI: 10.1002/9781119951438.eibc0662

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    A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis

    The EMBO Journal

    Volume 30, Issue 14, July 20, 2011, Pages: 2779–2792, Sabrina Büttner, Doris Ruli, F-Nora Vögtle, Lorenzo Galluzzi, Barbara Moitzi, Tobias Eisenberg, Oliver Kepp, Lukas Habernig, Didac Carmona-Gutierrez, Patrick Rockenfeller, Peter Laun, Michael Breitenbach, Chamel Khoury, Kai-Uwe Fröhlich, Gerald Rechberger, Chris Meisinger, Guido Kroemer and Frank Madeo

    Article first published online : 14 JUN 2011, DOI: 10.1038/emboj.2011.197

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    BH3-only proteins: Integrated control point of apoptosis

    International Journal of Cancer

    Volume 119, Issue 9, 1 November 2006, Pages: 2036–2043, Tsukasa Shibue and Tadatsugu Taniguchi

    Article first published online : 29 MAR 2006, DOI: 10.1002/ijc.21751

  17. BAK

    Standard Article

    Handbook of Metalloproteins

    Tudor Moldoveanu, Qian Liu, Douglas R Green and Kalle Gehring

    Published Online : 15 JUN 2008, DOI: 10.1002/0470028637.met237

  18. Structural Basis of Bcl-xL Recognition by a BH3-Mimetic α/β-Peptide Generated by Sequence-Based Design

    ChemBioChem

    Volume 12, Issue 13, September 5, 2011, Pages: 2025–2032, Dr. Erinna F. Lee, Assoc. Prof. Brian J. Smith, Dr. W. Seth Horne, Kelsey N. Mayer, Marco Evangelista, Prof. Peter M. Colman, Prof. Samuel H. Gellman and Dr. W. Douglas Fairlie

    Article first published online : 8 JUL 2011, DOI: 10.1002/cbic.201100314

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    BH3-only proteins: The death-puppeteer's wires

    Cytometry Part A

    Volume 77A, Issue 1, January 2010, Pages: 11–21, Fabio Ghiotto, Franco Fais and Silvia Bruno

    Article first published online : 6 NOV 2009, DOI: 10.1002/cyto.a.20819

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    PROTEINS OF THE BCL-2 FAMILY IN APOPTOSIS SIGNALLING: FROM MECHANISTIC INSIGHTS TO THERAPEUTIC OPPORTUNITIES

    Clinical and Experimental Pharmacology and Physiology

    Volume 31, Issue 3, March 2004, Pages: 119–128, Shing-Leng Chan and Victor C Yu

    Article first published online : 19 FEB 2004, DOI: 10.1111/j.1440-1681.2004.03975.x