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There are 1784 results for: content related to: Mu Opioid Receptor Antagonists: Recent Developments

  1. Mu-opioid antagonists for opioid-induced bowel dysfunction

    Intervention Review

    The Cochrane Library

    Ewan D McNicol, David Boyce, Roman Schumann and Daniel B Carr

    Published Online : 23 APR 2008, DOI: 10.1002/14651858.CD006332.pub2

  2. Efficacy and Safety of Mu-Opioid Antagonists in the Treatment of Opioid-Induced Bowel Dysfunction: Systematic Review and Meta-analysis of Randomized Controlled Trials

    Pain Medicine

    Volume 9, Issue 6, September 2008, Pages: 634–659, Ewan McNicol, David B. Boyce, Roman Schumann and Daniel Carr

    Article first published online : 26 JUL 2007, DOI: 10.1111/j.1526-4637.2007.00335.x

  3. Subcutaneous methylnaltrexone for treatment of acute opioid-induced constipation: Phase 2 study in rehabilitation after orthopedic surgery

    Journal of Hospital Medicine

    Volume 7, Issue 2, February 2012, Pages: 67–72, Lucas Anissian, Harry W. Schwartz, Kevin Vincent, Heather K. Vincent, Jennifer Carpenito, Nancy Stambler and Tage Ramakrishna

    Article first published online : 13 OCT 2011, DOI: 10.1002/jhm.943

  4. You have full text access to this OnlineOpen article
    Efficacy and Tolerability of Subcutaneous Methylnaltrexone in Patients with Advanced Illness and Opioid-Induced Constipation: A Responder Analysis of 2 Randomized, Placebo-Controlled Trials

    Pain Practice

    Volume 15, Issue 6, July 2015, Pages: 564–571, Srinivas R. Nalamachu, Joseph Pergolizzi, Robert Taylor Jr, Neal E. Slatkin, Andrew C. Barrett, Jing Yu, Enoch Bortey, Craig Paterson and William P. Forbes

    Article first published online : 10 MAY 2014, DOI: 10.1111/papr.12218

  5. Development and use of methylnaltrexone, a peripherally acting opioid antagonist, to treat side effects related to opioid use

    Drug Development Research

    Volume 70, Issue 6, September 2009, Pages: 403–416, Chun-Su Yuan, Joseph F. Foss, Wade A. Williams and Jonathan Moss

    Article first published online : 16 JUL 2009, DOI: 10.1002/ddr.20318

  6. Tolerability, Gut Effects, and Pharmacokinetics of Methylnaltrexone Following Repeated Intravenous Administration in Humans

    The Journal of Clinical Pharmacology

    Volume 45, Issue 5, May 2005, Pages: 538–546, Chun-Su Yuan, Harold Doshan, Martha R. Charney, Michael O'Connor, Theodore Karrison, S. A. Maleckar, Robert J. Israel and Jonathan Moss

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270004273491

  7. Effects of enteric-coated methylnaltrexone in preventing opioid-induced delay in oral-cecal transit time

    Clinical Pharmacology & Therapeutics

    Volume 67, Issue 4, April 2000, Pages: 398–404, Chun-Su Yuan, Joseph F. Foss, Michael O'Connor, Theodore Karrison, Joachim Osinski, Michael F. Roizen and Jonathan Moss

    Article first published online : 11 APR 2000, DOI: 10.1067/mcp.2000.105037

  8. Reversal of Opioid-Induced Bladder Dysfunction by Intravenous Naloxone and Methylnaltrexone

    Clinical Pharmacology & Therapeutics

    Volume 82, Issue 1, July 2007, Pages: 48–53, C E Rosow, P Gomery, T Y Chen, P Stefanovich, N Stambler and R Israel

    Article first published online : 28 MAR 2007, DOI: 10.1038/sj.clpt.6100164

  9. Methylnaltrexone for Opioid-Induced Constipation in Pediatric Oncology Patients

    Pediatric Blood & Cancer

    Volume 60, Issue 10, October 2013, Pages: 1667–1670, Amelia Rodrigues, Cherie Wong, Andrea Mattiussi, Sarah Alexander, Elaine Lau and L. Lee Dupuis

    Article first published online : 14 JUN 2013, DOI: 10.1002/pbc.24615

  10. Methylnaltrexone: Investigation of clinical applications

    Drug Development Research

    Volume 50, Issue 2, June 2000, Pages: 133–141, Chun-Su Yuan and Joseph F. Foss

    Article first published online : 11 AUG 2000, DOI: 10.1002/1098-2299(200006)50:2<133::AID-DDR1>3.0.CO;2-8

  11. The safety and efficacy of oral methylnaltrexone in preventing morphine-induced delay in oral-cecal transit time

    Clinical Pharmacology & Therapeutics

    Volume 61, Issue 4, April 1997, Pages: 467–475, Chun-Su Yuan, Joseph F. Foss, Joachim Osinski, Alicia Toledano, Michael F. Roizen and Jonathan Moss

    Article first published online : 2 APR 1997, DOI: 10.1016/S0009-9236(97)90197-1

  12. Methylnaltrexone prevents morphine-induced delay in oral-cecal transit time without affecting analgesia: A double-blind randomized placebo-controlled trial

    Clinical Pharmacology & Therapeutics

    Volume 59, Issue 4, April 1996, Pages: 469–475, Chun-Su Yuan, Joseph F. Foss, Michael O'Connor, Alicia Toledano, Michael F. Roizen and Jonathan Moss

    Article first published online : 26 APR 1996, DOI: 10.1016/S0009-9236(96)90117-4

  13. The Effect of Methylnaltrexone on the Side Effects of Intrathecal Morphine after Orthopedic Surgery under Spinal Anesthesia

    Pain Practice

    Volume 15, Issue 4, April 2015, Pages: 348–354, Farid Zand, Afshin Amini, Saman Asadi and Arash Farbood

    Article first published online : 27 FEB 2014, DOI: 10.1111/papr.12185

  14. Efficacy of Subcutaneous Methylnaltrexone in the Treatment of Opioid-Induced Constipation: A Responder Post Hoc Analysis

    Pain Medicine

    Volume 12, Issue 8, August 2011, Pages: 1223–1230, Edward Michna, Arnold J. Weil, Marc Duerden, Seth Schulman, Wenjin Wang, Evan Tzanis, Haiying Zhang, Dahong Yu, Amy Manley and Bruce Randazzo

    Article first published online : 2 AUG 2011, DOI: 10.1111/j.1526-4637.2011.01189.x

  15. Safety and Tolerance of Methylnaltrexone in Healthy Humans: A Randomized, Placebo-Controlled, Intravenous, Ascending-Dose, Pharmacokinetic Study

    The Journal of Clinical Pharmacology

    Volume 37, Issue 1, January 1997, Pages: 25–30, Joseph F. Foss, Michael F. O'Connor, Chun-Su Yuan, Michael Murphy, Jonathan Moss and Michael F. Roizen

    Article first published online : 8 MAR 2013, DOI: 10.1177/009127009703700105

  16. You have free access to this content
    Endogenously released opioids mediate meal-induced gastric relaxation via peripheral mu-opioid receptors

    Alimentary Pharmacology & Therapeutics

    Volume 33, Issue 5, March 2011, Pages: 607–614, P. Janssen, H. Pottel, R. Vos and J. Tack

    Article first published online : 29 DEC 2010, DOI: 10.1111/j.1365-2036.2010.04557.x

  17. Extended-release but not immediate-release and subcutaneous methylnaltrexone antagonizes the loperamide-induced delay of the whole-gut transit time in healthy subjects

    The Journal of Clinical Pharmacology

    Accepted manuscript online: 27 AUG 2015, Julia Kolbow, Christiane Modess, Danilo Wegner, Stefan Oswald, Martina Alice Maritz, Hélène Rey, Werner Weitschies and Werner Siegmund

    DOI: 10.1002/jcph.624

  18. You have free access to this content
    Methylnaltrexone for opioid induced constipation

    Future Prescriber

    Volume 9, Issue 2, May/August 2008, Pages: 13–17, Steve Chaplin

    Article first published online : 8 AUG 2008, DOI: 10.1002/fps.15

  19. Effects of methylnaltrexone in patients with narcotic bowel syndrome: a pilot observational study

    Internal Medicine Journal

    Volume 42, Issue 8, August 2012, Pages: 907–912, P. R. Gibson and G. Morrison

    Article first published online : 21 AUG 2012, DOI: 10.1111/j.1445-5994.2012.02726.x

  20. Effects of remifentanil on the esophagogastric junction and swallowing

    Acta Anaesthesiologica Scandinavica

    Volume 57, Issue 8, September 2013, Pages: 1002–1009, JOHANNA SAVILAMPI, REBECCA AHLSTRAND, ANDERS MAGNUSON and MAGNUS WATTWIL

    Article first published online : 29 MAY 2013, DOI: 10.1111/aas.12134