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There are 34531 results for: content related to: Natural-Product-Like Spiroketals and Fused Bicyclic Acetals as Potential Therapeutic Agents for B-Cell Chronic Lymphocytic Leukaemia

  1. Small-Molecule Inhibitors of PDK1

    ChemMedChem

    Volume 3, Issue 12, December 15, 2008, Pages: 1810–1838, Christian Peifer and Dario R. Alessi

    Version of Record online : 29 OCT 2008, DOI: 10.1002/cmdc.200800195

  2. De Novo Design, Synthesis and Evaluation of Benzylpiperazine Derivatives as Highly Selective Binders of Mcl-1

    ChemMedChem

    Volume 8, Issue 12, December 2013, Pages: 1986–2014, Dr. Xiao Ding, Dr. Yan Li, Li Lv, Mi Zhou, Dr. Li Han, Zhengxi Zhang, Dr. Qian Ba, Dr. Jingquan Li, Prof. Hui Wang, Prof. Hong Liu and Prof. Renxiao Wang

    Version of Record online : 9 OCT 2013, DOI: 10.1002/cmdc.201300316

  3. Contribution of Explicit Solvent Effects to the Binding Affinity of Small-Molecule Inhibitors in Blood Coagulation Factor Serine Proteases

    ChemMedChem

    Volume 6, Issue 6, June 6, 2011, Pages: 1049–1066, Dr. Robert Abel, Dr. Noeris K. Salam, Dr. John Shelley, Dr. Ramy Farid, Prof. Richard A. Friesner and Dr. Woody Sherman

    Version of Record online : 19 APR 2011, DOI: 10.1002/cmdc.201000533

  4. Development of Diaminoquinazoline Histone Lysine Methyltransferase Inhibitors as Potent Blood-Stage Antimalarial Compounds

    ChemMedChem

    Volume 9, Issue 10, October 2014, Pages: 2360–2373, Dr. Sandeep Sundriyal, Dr. Nicholas A. Malmquist, Dr. Joachim Caron, Scott Blundell, Dr. Feng Liu, Xin Chen, Nitipol Srimongkolpithak, Prof. Jian Jin, Prof. Susan A. Charman, Prof. Artur Scherf and Dr. Matthew J. Fuchter

    Version of Record online : 9 JUL 2014, DOI: 10.1002/cmdc.201402098

  5. Novel Inhibitors of Checkpoint Kinase 1

    ChemMedChem

    Volume 2, Issue 11, November 12, 2007, Pages: 1571–1585, Kenneth L. Arrington and Vadim Y. Dudkin

    Version of Record online : 13 SEP 2007, DOI: 10.1002/cmdc.200700131

  6. Synthesis and Structure–Activity Relationship Studies of HIV-1 Virion Infectivity Factor (Vif) Inhibitors that Block Viral Replication

    ChemMedChem

    Volume 7, Issue 7, July 2012, Pages: 1217–1229, Dr. Akbar Ali, Dr. Jinhua Wang, Robin S. Nathans, Dr. Hong Cao, Dr. Natalia Sharova, Prof. Dr. Mario Stevenson and Prof. Dr. Tariq M. Rana

    Version of Record online : 3 MAY 2012, DOI: 10.1002/cmdc.201200079

  7. Advances in Targeting Voltage-Gated Sodium Channels with Small Molecules

    ChemMedChem

    Volume 7, Issue 10, October 2012, Pages: 1712–1740, Dr. Antonio Nardi, Dr. Nils Damann, Dr. Torsten Hertrampf and Dr. Achim Kless

    Version of Record online : 4 SEP 2012, DOI: 10.1002/cmdc.201200298

    Corrected by:

    Corrigendum: Corrigendum: Advances in Targeting Voltage-Gated Sodium Channels with Small Molecules

    Vol. 7, Issue 11, 1874, Version of Record online: 29 OCT 2012

  8. Carbohydrates as Scaffolds in Drug Discovery

    ChemMedChem

    Volume 1, Issue 11, November 13, 2006, Pages: 1164–1194, Wim Meutermans, Giang Thanh Le and Bernd Becker

    Version of Record online : 19 SEP 2006, DOI: 10.1002/cmdc.200600150

  9. A 3D QSAR Model of 17β-HSD1 Inhibitors Based on a Thieno[2,3-d]pyrimidin-4(3H)-one Core Applying Molecular Dynamics Simulations and Ligand–Protein Docking

    ChemMedChem

    Volume 3, Issue 3, March 14, 2008, Pages: 461–472, Sampo Karkola, Annamaria Lilienkampf and Kristiina Wähälä

    Version of Record online : 25 JAN 2008, DOI: 10.1002/cmdc.200700271

  10. Novel Type II Fatty Acid Biosynthesis (FAS II) Inhibitors as Multistage Antimalarial Agents

    ChemMedChem

    Volume 8, Issue 3, March 2013, Pages: 442–461, Dr. Florian C. Schrader, Dr. Serghei Glinca, Dr. Julia M. Sattler, Dr. Hans-Martin Dahse, Gustavo A. Afanador, Prof. Dr. Sean T. Prigge, Prof. Dr. Michael Lanzer, Dr. Ann-Kristin Mueller, Prof. Dr. Gerhard Klebe and Prof. Dr. Martin Schlitzer

    Version of Record online : 22 JAN 2013, DOI: 10.1002/cmdc.201200407

  11. Functionalization of Fluorinated Benzenesulfonamides and Their Inhibitory Properties toward Carbonic Anhydrases

    ChemMedChem

    Volume 10, Issue 4, April 2015, Pages: 662–687, Dr. Virginija Dudutienė, Dr. Asta Zubrienė, Alexey Smirnov, David D. Timm, Joana Smirnovienė, Justina Kazokaitė, Vilma Michailovienė, Audrius Zakšauskas, Dr. Elena Manakova, Dr. Saulius Gražulis and Prof. Daumantas Matulis

    Version of Record online : 10 MAR 2015, DOI: 10.1002/cmdc.201402490

  12. Discovery, Synthesis, and Optimization of Diarylisoxazole-3-carboxamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore

    ChemMedChem

    Volume 10, Issue 10, October 2015, Pages: 1655–1671, Dr. Sudeshna Roy, Dr. Justina Šileikytė, Dr. Marco Schiavone, Benjamin Neuenswander, Prof. Dr. Francesco Argenton, Prof. Dr. Jeffrey Aubé, Dr. Michael P. Hedrick, Dr. Thomas D. Y. Chung, Prof. Dr. Michael A. Forte, Prof. Dr. Paolo Bernardi and Dr. Frank J. Schoenen

    Version of Record online : 18 AUG 2015, DOI: 10.1002/cmdc.201500284

  13. Structure–Activity Relationships and Mechanism of Action of Eph–ephrin Antagonists: Interaction of Cholanic Acid with the EphA2 Receptor

    ChemMedChem

    Volume 7, Issue 6, June 2012, Pages: 1071–1083, Dr. Massimiliano Tognolini, Dr. Matteo Incerti, Iftiin Hassan-Mohamed, Dr. Carmine Giorgio, Simonetta Russo, Dr. Renato Bruni, Dr. Barbara Lelli, Prof. Luisa Bracci, Dr. Roberta Noberini, Prof. Elena B. Pasquale, Prof. Elisabetta Barocelli, Prof. Paola Vicini, Prof. Marco Mor and Dr. Alessio Lodola

    Version of Record online : 23 APR 2012, DOI: 10.1002/cmdc.201200102

  14. Probing Binding and Cellular Activity of Pyrrolidinone and Piperidinone Small Molecules Targeting the Urokinase Receptor

    ChemMedChem

    Volume 8, Issue 12, December 2013, Pages: 1963–1977, Dr. Timmy Mani, Dr. Degang Liu, Dr. Donghui Zhou, Dr. Liwei Li, Dr. William Eric Knabe, Fang Wang, Prof. Kyungsoo Oh and Prof. Samy O. Meroueh

    Version of Record online : 2 OCT 2013, DOI: 10.1002/cmdc.201300340

  15. 3D-QSAR-Assisted Drug Design: Identification of a Potent Quinazoline-Based Aurora Kinase Inhibitor

    ChemMedChem

    Volume 8, Issue 1, January 2013, Pages: 136–148, Dr. Yi-Yu Ke, Dr. Hui-Yi Shiao, Dr. Yung Chang Hsu, Dr. Chang-Ying Chu, Dr. Wen-Chieh Wang, Yen-Chun Lee, Dr. Wen-Hsing Lin, Chun-Hwa Chen, Dr. John T. A. Hsu, Chun-Wei Chang, Dr. Cheng-Wei Lin, Dr. Teng-Kuang Yeh, Dr. Yu-Sheng Chao, Dr. Mohane Selvaraj Coumar and Dr. Hsing-Pang Hsieh

    Version of Record online : 22 NOV 2012, DOI: 10.1002/cmdc.201200464

  16. Synthesis and Evaluation of 3,4-Dihydropyrimidin-2(1H)-ones as Sodium Iodide Symporter Inhibitors

    ChemMedChem

    Volume 8, Issue 1, January 2013, Pages: 104–111, Pierre Lacotte, Celine Puente and Dr. Yves Ambroise

    Version of Record online : 6 NOV 2012, DOI: 10.1002/cmdc.201200417

  17. A Medicinal-Chemistry-Guided Approach to Selective and Druglike Sigma 1 Ligands

    ChemMedChem

    Volume 1, Issue 1, January 16, 2006, Pages: 140–154, Jordi Corbera, David Vaño, Daniel Martínez, José M. Vela, Daniel Zamanillo, Alberto Dordal, Francesc Andreu, Enric Hernandez, Raquel Perez, Marisol Escriche, Leonardo Salgado, Sandra Yeste, Maria Teresa Serafini, Rosalia Pascual, Júlia Alegre, Maria Carme Calvet, Núria Cano, Mónica Carro, Helmut Buschmann and Jörg Holenz

    Version of Record online : 5 JAN 2006, DOI: 10.1002/cmdc.200500034

  18. Orexin Receptor Antagonists: A New Concept In CNS Disorders?

    ChemMedChem

    Volume 5, Issue 8, August 2, 2010, Pages: 1197–1214, John Gatfield, Catherine Brisbare-Roch, Francois Jenck and Christoph Boss

    Version of Record online : 11 JUN 2010, DOI: 10.1002/cmdc.201000132

  19. 2-Acylaminopyridin-4-ylimidazoles as p38 MAP Kinase Inhibitors: Design, Synthesis, and Biological and Metabolic Evaluations

    ChemMedChem

    Volume 4, Issue 11, November 2, 2009, Pages: 1939–1948, Katharina Ziegler, Dominik R. J. Hauser, Anke Unger, Wolfgang Albrecht and Stefan A. Laufer

    Version of Record online : 3 SEP 2009, DOI: 10.1002/cmdc.200900242

  20. On the Way to Selective PARP-2 Inhibitors. Design, Synthesis, and Preliminary Evaluation of a Series of Isoquinolinone Derivatives

    ChemMedChem

    Volume 3, Issue 6, June 16, 2008, Pages: 914–923, Roberto Pellicciari, Emidio Camaioni, Gabriele Costantino, Laura Formentini, Paola Sabbatini, Francesco Venturoni, Gökçen Eren, Daniele Bellocchi, Alberto Chiarugi and Flavio Moroni

    Version of Record online : 11 APR 2008, DOI: 10.1002/cmdc.200800010