Search Results

There are 3753 results for: content related to: Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity

  1. You have free access to this content
    Quantification of the HIV transcriptional activator complex in live cells by image-based protein–protein interaction analysis

    Genes to Cells

    Volume 21, Issue 7, July 2016, Pages: 706–716, Kaori Asamitsu, Katsumi Omagari, Tomoya Okuda, Yurina Hibi and Takashi Okamoto

    Version of Record online : 19 MAY 2016, DOI: 10.1111/gtc.12375

  2. T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes

    Journal of Cellular Physiology

    Volume 224, Issue 1, July 2010, Pages: 84–93, Eugene C. Dow, Hongbing Liu and Andrew P. Rice

    Version of Record online : 3 MAR 2010, DOI: 10.1002/jcp.22096

  3. You have free access to this content
    The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

    The EMBO Journal

    Volume 27, Issue 13, July 9, 2008, Pages: 1907–1918, Sonja Baumli, Graziano Lolli, Edward D Lowe, Sonia Troiani, Luisa Rusconi, Alex N Bullock, Judit É Debreczeni, Stefan Knapp and Louise N Johnson

    Version of Record online : 19 JUN 2008, DOI: 10.1038/emboj.2008.121

  4. Selective control of gene expression by CDK9 in human cells

    Journal of Cellular Physiology

    Volume 222, Issue 1, January 2010, Pages: 200–208, Judit Garriga, Hongbo Xie, Zoran Obradovic and Xavier Graña

    Version of Record online : 24 SEP 2009, DOI: 10.1002/jcp.21938

  5. Cdk9 T-loop phosphorylation is regulated by the calcium signaling pathway

    Journal of Cellular Physiology

    Volume 227, Issue 2, February 2012, Pages: 609–617, Rajesh Ramakrishnan and Andrew P. Rice

    Version of Record online : 23 NOV 2011, DOI: 10.1002/jcp.22760

  6. Distinct regions of cyclinT1 are required for binding to CDK9 and for recruitment to the HIV-1 Tat/TAR complex

    Journal of Cellular Biochemistry

    Volume 81, Issue S36, 2001, Pages: 247–253, Alessandro Fraldi, Paolo Licciardo, Barbara Majello, Antonio Giordano and Luigi Lania

    Version of Record online : 25 MAY 2001, DOI: 10.1002/jcb.1149

  7. You have free access to this content
    1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription

    British Journal of Pharmacology

    Volume 171, Issue 22, November 2014, Pages: 5059–5075, Tatyana Ammosova, Maxim Platonov, Andrei Ivanov, Yasemin Saygideğer Kont, Namita Kumari, Kylene Kehn-Hall, Marina Jerebtsova, Amol A Kulkarni, Aykut Üren, Dmytro Kovalskyy and Sergei Nekhai

    Version of Record online : 27 OCT 2014, DOI: 10.1111/bph.12863

  8. MyoD recruits the cdk9/cyclin T2 complex on Myogenic-genes regulatory regions

    Journal of Cellular Physiology

    Volume 206, Issue 3, March 2006, Pages: 807–813, Cristina Giacinti, Luigi Bagella, Pier Lorenzo Puri, Antonio Giordano and Cristiano Simone

    Version of Record online : 21 OCT 2005, DOI: 10.1002/jcp.20523

  9. The regulation of HIV-1 transcription: Molecular targets for chemotherapeutic intervention

    Medicinal Research Reviews

    Volume 26, Issue 5, September 2006, Pages: 595–625, Miguel Stevens, Erik De Clercq and Jan Balzarini

    Version of Record online : 12 JUL 2006, DOI: 10.1002/med.20081

  10. You have full text access to this OnlineOpen article
    P-TEFb goes viral

    Inside the Cell

    Volume 1, Issue 2, April 2016, Pages: 106–116, Justyna Zaborowska, Nur F. Isa and Shona Murphy

    Version of Record online : 25 NOV 2015, DOI: 10.1002/icl3.1037

  11. You have free access to this content
    Interaction of Sp1 transcription factor with HIV-1 Tat protein: looking for cellular partners

    FEBS Letters

    Volume 543, Issue 1-3, May 22, 2003, Pages: 61–65, Arianna Loregian, Katia Bortolozzo, Silvia Boso, Antonella Caputo and Giorgio Palù

    Version of Record online : 24 APR 2003, DOI: 10.1016/S0014-5793(03)00399-5

  12. Inhibition of P-TEFb disrupts global transcription, oocyte maturation, and embryo development in the mouse

    genesis

    Volume 54, Issue 9, September 2016, Pages: 470–482, Reza K. Oqani, Tao Lin, Jae Eun Lee, So Yeon Kim, Soo Jin Sa, Je Seok Woo and Dong Il Jin

    Version of Record online : 18 AUG 2016, DOI: 10.1002/dvg.22961

  13. Cdk9 phosphorylates p53 on serine 392 independently of CKII

    Journal of Cellular Physiology

    Volume 208, Issue 3, September 2006, Pages: 602–612, Pier Paolo Claudio, Jianqi Cui, Mohammad Ghafouri, Chiara Mariano, Martyn K. White, Mahmut Safak, Joel B. Sheffield, Antonio Giordano, Kamel Khalili, Shohreh Amini and Bassel E. Sawaya

    Version of Record online : 1 JUN 2006, DOI: 10.1002/jcp.20698

  14. You have free access to this content
    Three cyclin-dependent kinases preferentially phosphorylate different parts of the C-terminal domain of the large subunit of RNA polymerase II

    European Journal of Biochemistry

    Volume 271, Issue 5, March 2004, Pages: 1004–1014, Reena Pinhero, Peter Liaw, Kimberly Bertens and Krassimir Yankulov

    Version of Record online : 11 FEB 2004, DOI: 10.1111/j.1432-1033.2004.04002.x

  15. You have free access to this content
    Characterization of molecular and cellular functions of the cyclin-dependent kinase CDK9 using a novel specific inhibitor

    British Journal of Pharmacology

    Volume 171, Issue 1, January 2014, Pages: 55–68, T K Albert, C Rigault, J Eickhoff, K Baumgart, C Antrecht, B Klebl, G Mittler and M Meisterernst

    Version of Record online : 10 DEC 2013, DOI: 10.1111/bph.12408

  16. CDK9: A key player in Cancer and Other Diseases

    Journal of Cellular Biochemistry

    Accepted manuscript online: 19 JUL 2017, Lia Carolina Franco, Fátima Morales, Silvia Boffo and Antonio Giordano

    DOI: 10.1002/jcb.26293

  17. You have free access to this content
    Cyclin-dependent kinase 9–cyclin K functions in the replication stress response

    EMBO reports

    Volume 11, Issue 11, November 2010, Pages: 876–882, David S Yu, Runxiang Zhao, Emory L Hsu, Jennifer Cayer, Fei Ye, Yan Guo, Yu Shyr and David Cortez

    Version of Record online : 8 OCT 2010, DOI: 10.1038/embor.2010.153

  18. You have full text access to this OnlineOpen article
    P-TEFb goes viral

    BioEssays

    Volume 38, Issue S1, July 2016, Pages: S75–S85, Justyna Zaborowska, Nur F. Isa and Shona Murphy

    Version of Record online : 15 JUL 2016, DOI: 10.1002/bies.201670912

  19. Differential localization and expression of the Cdk9 42k and 55k isoforms

    Journal of Cellular Physiology

    Volume 203, Issue 1, April 2005, Pages: 251–260, Hongbing Liu and Christine H. Herrmann

    Version of Record online : 27 SEP 2004, DOI: 10.1002/jcp.20224

  20. You have free access to this content
    Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages

    The EMBO Journal

    Volume 17, Issue 13, July 1, 1998, Pages: 3681–3691, Qiang Zhou, Dan Chen, Erik Pierstorff and Kunxin Luo

    Version of Record online : 1 JUL 1998, DOI: 10.1093/emboj/17.13.3681