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There are 4586 results for: content related to: An Efficient Combinatorial Synthesis of Allocolchicine Analogues via a Triple Cascade Reaction and their Evaluation as Inhibitors of Insulin Aggregation

  1. De Novo Design, Synthesis and Evaluation of Benzylpiperazine Derivatives as Highly Selective Binders of Mcl-1


    Volume 8, Issue 12, December 2013, Pages: 1986–2014, Dr. Xiao Ding, Dr. Yan Li, Li Lv, Mi Zhou, Dr. Li Han, Zhengxi Zhang, Dr. Qian Ba, Dr. Jingquan Li, Prof. Hui Wang, Prof. Hong Liu and Prof. Renxiao Wang

    Article first published online : 9 OCT 2013, DOI: 10.1002/cmdc.201300316

  2. Probing Binding and Cellular Activity of Pyrrolidinone and Piperidinone Small Molecules Targeting the Urokinase Receptor


    Volume 8, Issue 12, December 2013, Pages: 1963–1977, Dr. Timmy Mani, Dr. Degang Liu, Dr. Donghui Zhou, Dr. Liwei Li, Dr. William Eric Knabe, Fang Wang, Prof. Kyungsoo Oh and Prof. Samy O. Meroueh

    Article first published online : 2 OCT 2013, DOI: 10.1002/cmdc.201300340

  3. Drug Discovery Alliances in India—Indications, Targets, and New Chemical Entities


    Volume 9, Issue 1, January 2014, Pages: 43–60, Dr. Edmond Differding

    Article first published online : 8 OCT 2013, DOI: 10.1002/cmdc.201300341

  4. Phylogeny of Berosini (Coleoptera: Hydrophilidae, Hydrophilinae) based on larval and adult characters, and evolutionary scenarios related to habitat shift in larvae

    Systematic Entomology

    Volume 33, Issue 4, October 2008, Pages: 635–650, MIGUEL ARCHANGELSKY

    Article first published online : 1 OCT 2008, DOI: 10.1111/j.1365-3113.2008.00425.x

  5. Bromodomains and Their Pharmacological Inhibitors


    Volume 9, Issue 3, March 2014, Pages: 438–464, Dr. Daniel Gallenkamp, Dr. Kathy A. Gelato, Dr. Bernard Haendler and Dr. Hilmar Weinmann

    Article first published online : 4 FEB 2014, DOI: 10.1002/cmdc.201300434

  6. Structure-Based and Fragment-Based GPCR Drug Discovery


    Volume 9, Issue 2, February 2014, Pages: 256–275, Dr. Stephen P. Andrews, Dr. Giles A. Brown and Dr. John A. Christopher

    Article first published online : 18 DEC 2013, DOI: 10.1002/cmdc.201300382

  7. Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity


    Volume 8, Issue 12, December 2013, Pages: 1941–1953, Dr. Luca Sancineto, Dr. Nunzio Iraci, Dr. Serena Massari, Dr. Vanessa Attanasio, Dr. Gianmarco Corazza, Dr. Maria Letizia Barreca, Dr. Stefano Sabatini, Dr. Giuseppe Manfroni, Dr. Nilla Roberta Avanzi, Prof. Violetta Cecchetti, Prof. Christophe Pannecouque, Prof. Alessandro Marcello and Dr. Oriana Tabarrini

    Article first published online : 21 OCT 2013, DOI: 10.1002/cmdc.201300287

  8. Synthetic and Biological Studies of Tubulin Targeting C2-Substituted 7-Deazahypoxanthines Derived from Marine Alkaloid Rigidins


    Volume 9, Issue 7, July 2014, Pages: 1428–1435, Robert Scott, Dr. Menuka Karki, Mary R. Reisenauer, Roberta Rodrigues, Dr. Ramesh Dasari, W. Ross Smith, Prof. Dr. Stephen C. Pelly, Prof. Dr. Willem A. L. van Otterlo, Prof. Dr. Charles B. Shuster, Prof. Dr. Snezna Rogelj, Prof. Dr. Igor V. Magedov, Prof. Dr. Liliya V. Frolova and Prof. Dr. Alexander Kornienko

    Article first published online : 18 MAR 2014, DOI: 10.1002/cmdc.201300532

  9. Synthesis of Indole-Derived Allocolchicine Congeners through Pd-Catalyzed Intramolecular C-H Arylation Reaction

    European Journal of Organic Chemistry

    Volume 2014, Issue 29, October 2014, Pages: 6481–6492, Nikolay S. Sitnikov, Antonina S. Kokisheva, Georgy K. Fukin, Jörg-Martin Neudörfl, Hannah Sutorius, Aram Prokop, Valery V. Fokin, Hans-Günther Schmalz and Alexey Yu. Fedorov

    Article first published online : 4 SEP 2014, DOI: 10.1002/ejoc.201402850

  10. New Members of ChemMedChem′s Editorial and International Advisory Boards


    Volume 9, Issue 1, January 2014, Pages: 14–18,

    Article first published online : 23 DEC 2013, DOI: 10.1002/cmdc.201300491

  11. Glucosylceramide Mimics: Highly Potent GCase Inhibitors and Selective Pharmacological Chaperones for Mutations Associated with Types 1 and 2 Gaucher Disease


    Volume 8, Issue 11, November 2013, Pages: 1805–1817, Wojciech Schönemann, Dr. Estelle Gallienne, Dr. Kyoko Ikeda-Obatake, Dr. Naoki Asano, Shinpei Nakagawa, Dr. Atsushi Kato, Dr. Isao Adachi, Dr. Marcin Górecki, Prof. Jadwiga Frelek and Prof. Olivier R. Martin

    Article first published online : 2 OCT 2013, DOI: 10.1002/cmdc.201300327

  12. Synthesis and Anti-Plasmodium Activity of Benzimidazole Analogues Structurally Related to Astemizole


    Volume 8, Issue 11, November 2013, Pages: 1795–1804, Dr. Gheorghe Roman, Dr. Ian E. Crandall and Prof. Walter A. Szarek

    Article first published online : 10 SEP 2013, DOI: 10.1002/cmdc.201300172

  13. Histone Deacetylase Inhibitors with Enhanced Enzymatic Inhibition Effects and Potent in vitro and in vivo Antitumor Activities


    Volume 9, Issue 3, March 2014, Pages: 638–648, Dr. Lei Zhang, Dr. Yingjie Zhang, Prof. C. James Chou, Dr. Elizabeth S. Inks, Dr. Xuejian Wang, Xiaoguang Li, Jinning Hou and Prof. Wenfang Xu

    Article first published online : 12 NOV 2013, DOI: 10.1002/cmdc.201300297

  14. 3-Aminoazetidin-2-one Derivatives as N-Acylethanolamine Acid Amidase (NAAA) Inhibitors Suitable for Systemic Administration


    Volume 9, Issue 7, July 2014, Pages: 1602–1614, Dr. Annalisa Fiasella, Dr. Andrea Nuzzi, Dr. Maria Summa, Dr. Andrea Armirotti, Dr. Glauco Tarozzo, Prof. Giorgio Tarzia, Prof. Marco Mor, Dr. Fabio Bertozzi, Dr. Tiziano Bandiera and Prof. Daniele Piomelli

    Article first published online : 14 MAY 2014, DOI: 10.1002/cmdc.201300546

  15. Synthesis of Diverse 6-Oxa-allocolchicinoids by a Suzuki–Miyaura Coupling, Acid-Catalyzed Intramolecular Transacetali­zation Strategy

    European Journal of Organic Chemistry

    Dharmendra B. Yadav, Lebusetsa Taleli, Alet E. van der Westhuyzen, Manuel A. Fernandes, Maxim Dragoun, Aram Prokop, Hans-Günther Schmalz, Charles B. de Koning and Willem A. L. van Otterlo

    Article first published online : 8 JUL 2015, DOI: 10.1002/ejoc.201500573

  16. Discovery of 5′′-Chloro-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2′:5′,3′′-terpyridine-3′-carboxamide (MK-1064): A Selective Orexin 2 Receptor Antagonist (2-SORA) for the Treatment of Insomnia


    Volume 9, Issue 2, February 2014, Pages: 311–322, Dr. Anthony J. Roecker, Swati P. Mercer, John D. Schreier, Dr. Christopher D. Cox, Dr. Mark E. Fraley, Justin T. Steen, Wei Lemaire, Joseph G. Bruno, C. Meacham Harrell, Susan L. Garson, Dr. Anthony L. Gotter, Steven V. Fox, Joanne Stevens, Dr. Pamela L. Tannenbaum, Dr. Thomayant Prueksaritanont, Dr. Tamara D. Cabalu, Dr. Donghui Cui, Joyce Stellabott, Dr. George D. Hartman, Dr. Steven D. Young, Dr. Christopher J. Winrow, Dr. John J. Renger and Dr. Paul J. Coleman

    Article first published online : 27 DEC 2013, DOI: 10.1002/cmdc.201300447

  17. Identification of Chiral Alkenyl- and Alkynylcarbinols as Pharmacophores for Potent Cytotoxicity


    Volume 8, Issue 11, November 2013, Pages: 1779–1786, Dr. Dounia El Arfaoui, Dymytrii Listunov, Isabelle Fabing, Mohamed Oukessou, Céline Frongia, Dr. Valérie Lobjois, Arnaud Samson, Dr. Frédéric Ausseil, Prof. Abdeslem Ben-Tama, Prof. El Mestafa El Hadrami, Prof. Remi Chauvin and Dr. Yves Génisson

    Article first published online : 6 SEP 2013, DOI: 10.1002/cmdc.201300230

  18. Time-Dependent Diaryl Ether Inhibitors of InhA: Structure–Activity Relationship Studies of Enzyme Inhibition, Antibacterial Activity, and in vivo Efficacy


    Volume 9, Issue 4, April 2014, Pages: 776–791, Dr. Pan Pan, Dr. Susan E. Knudson, Dr. Gopal R. Bommineni, Dr. Huei-Jiun Li, Cheng-Tsung Lai, Dr. Nina Liu, Prof. Miguel Garcia-Diaz, Prof. Carlos Simmerling, Dr. Sachindra S. Patil, Prof. Richard A. Slayden and Prof. Peter J. Tonge

    Article first published online : 11 MAR 2014, DOI: 10.1002/cmdc.201300429

  19. para-Substituted 2-Phenyl-3,4-dihydroquinazolin-4-ones As Potent and Selective Tankyrase Inhibitors


    Volume 8, Issue 12, December 2013, Pages: 1978–1985, Dr. Teemu Haikarainen, Dr. Jarkko Koivunen, Mohit Narwal, Harikanth Venkannagari, Ezeogo Obaji, Päivi Joensuu, Prof. Taina Pihlajaniemi and Dr. Lari Lehtiö

    Article first published online : 15 OCT 2013, DOI: 10.1002/cmdc.201300337

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    Structure–Activity Relationships of Quinoxaline-Based 5-HT3A and 5-HT3AB Receptor-Selective Ligands


    Volume 8, Issue 6, June 2013, Pages: 946–955, Dr. Andrew J. Thompson, Dr. Mark H. P. Verheij, Dr. Jacqueline E. van Muijlwijk-Koezen, Prof. Sarah C. R. Lummis, Prof. Rob Leurs and Dr. Iwan J. P. de Esch

    Article first published online : 2 MAY 2013, DOI: 10.1002/cmdc.201300032