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There are 42833 results for: content related to: An Update on Lysine Deacylases Targeting the Expanding “Acylome”

  1. You have full text access to this OnlineOpen article
    Alternate deacylating specificities of the archaeal sirtuins Sir2Af1 and Sir2Af2

    Protein Science

    Volume 23, Issue 12, December 2014, Pages: 1686–1697, Alison E. Ringel, Christina Roman and Cynthia Wolberger

    Version of Record online : 1 OCT 2014, DOI: 10.1002/pro.2546

  2. The Current State of NAD+-Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets

    Medicinal Research Reviews

    Matthias Schiedel, Dina Robaa, Tobias Rumpf, Wolfgang Sippl and Manfred Jung

    Version of Record online : 17 JAN 2017, DOI: 10.1002/med.21436

  3. Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules

    Angewandte Chemie

    Volume 129, Issue 4, January 19, 2017, Pages: 1027–1031, Weijie You, Dr. Dante Rotili, Dr. Tie-Mei Li, Dr. Christian Kambach, Dr. Marat Meleshin, Prof. Dr. Mike Schutkowski, Prof. Dr. Katrin F. Chua, Prof. Dr. Antonello Mai and Prof. Dr. Clemens Steegborn

    Version of Record online : 19 DEC 2016, DOI: 10.1002/ange.201610082

  4. Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules

    Angewandte Chemie International Edition

    Volume 56, Issue 4, January 19, 2017, Pages: 1007–1011, Weijie You, Dr. Dante Rotili, Dr. Tie-Mei Li, Dr. Christian Kambach, Dr. Marat Meleshin, Prof. Dr. Mike Schutkowski, Prof. Dr. Katrin F. Chua, Prof. Dr. Antonello Mai and Prof. Dr. Clemens Steegborn

    Version of Record online : 19 DEC 2016, DOI: 10.1002/anie.201610082

  5. The ɛ-Amino Group of Protein Lysine Residues Is Highly Susceptible to Nonenzymatic Acylation by Several Physiological Acyl-CoA Thioesters

    ChemBioChem

    Volume 16, Issue 16, November 2, 2015, Pages: 2337–2347, Zeljko Simic, Dr. Matthias Weiwad, Dr. Angelika Schierhorn, Dr. Clemens Steegborn and Dr. Mike Schutkowski

    Version of Record online : 18 SEP 2015, DOI: 10.1002/cbic.201500364

  6. You have free access to this content
    Regulation of SIRT6 protein levels by nutrient availability

    FEBS Letters

    Volume 582, Issue 5, March 05, 2008, Pages: 543–548, Yariv Kanfi, Ronnie Shalman, Victoria Peshti, Shmuel N. Pilosof, Yosi M. Gozlan, Kevin J. Pearson, Batya Lerrer, Danesh Moazed, Jean-Christophe Marine, Rafael de Cabo and Haim Y. Cohen

    Version of Record online : 31 JAN 2008, DOI: 10.1016/j.febslet.2008.01.019

  7. The Discovery of a Highly Selective 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one SIRT2 Inhibitor that is Neuroprotective in an in vitro Parkinson’s Disease Model

    ChemMedChem

    Volume 10, Issue 1, January 2015, Pages: 69–82, Dr. Paolo Di Fruscia, Emmanouil Zacharioudakis, Chang Liu, Dr. Sébastien Moniot, Sasiwan Laohasinnarong, Mattaka Khongkow, Ian F. Harrison, Konstantina Koltsida, Dr. Christopher R. Reynolds, Karin Schmidtkunz, Prof. Dr. Manfred Jung, Dr. Kathryn L. Chapman, Prof. Dr. Clemens Steegborn, Prof. David T. Dexter, Prof. Michael J. E. Sternberg, Prof. Eric W.-F. Lam and Dr. Matthew J. Fuchter

    Version of Record online : 13 NOV 2014, DOI: 10.1002/cmdc.201402431

  8. Sirtuin activators and inhibitors

    BioFactors

    Volume 38, Issue 5, September/October 2012, Pages: 349–359, José M. Villalba and Francisco J. Alcaín

    Version of Record online : 25 JUN 2012, DOI: 10.1002/biof.1032

  9. Mitochondrial sirtuins – a new therapeutic target for repair and protection in multiple sclerosis

    European Journal of Neuroscience

    Volume 35, Issue 12, June 2012, Pages: 1887–1893, C. M. Rice, M. Sun, K. Kemp, E. Gray, A. Wilkins and N. J. Scolding

    Version of Record online : 19 JUN 2012, DOI: 10.1111/j.1460-9568.2012.08150.x

  10. You have free access to this content
    Sirtuin-dependent epigenetic regulation in the maintenance of genome integrity

    The FEBS Journal

    Volume 282, Issue 9, May 2015, Pages: 1745–1767, Laia Bosch-Presegué and Alejandro Vaquero

    Version of Record online : 13 OCT 2014, DOI: 10.1111/febs.13053

  11. You have full text access to this OnlineOpen article
    Highlights of the Keystone Symposium: sirtuins in metabolism, aging and disease

    EMBO Molecular Medicine

    Volume 4, Issue 7, July 2012, Pages: 557–560, Michele M. Maxwell, Julien Francisco Zaldivar-Jolissaint, Antonello Mai, Tiago F. Outeiro and Aleksey G. Kazanstev

    Version of Record online : 18 MAY 2012, DOI: 10.1002/emmm.201201452

    Corrected by:

    Corrigendum: Corrigendum

    Vol. 4, Issue 8, 840, Version of Record online: 3 AUG 2012

  12. Comparative interactomes of SIRT6 and SIRT7: Implication of functional links to aging

    PROTEOMICS

    Volume 14, Issue 13-14, July 2014, Pages: 1610–1622, Namgyu Lee, Dae-Kyum Kim, Eung-Sam Kim, Sung Jin Park, Jung-Hee Kwon, Jihye Shin, Seon-Min Park, Young Ho Moon, Hee Jung Wang, Yong Song Gho and Kwan Yong Choi

    Version of Record online : 28 MAY 2014, DOI: 10.1002/pmic.201400001

  13. Chemical Probing of the Human Sirtuin 5 Active Site Reveals Its Substrate Acyl Specificity and Peptide-Based Inhibitors

    Angewandte Chemie

    Volume 126, Issue 40, September 26, 2014, Pages: 10904–10908, Claudia Roessler, Theresa Nowak, Martin Pannek, Dr. Melanie Gertz, Giang T. T. Nguyen, Michael Scharfe, Dr. Ilona Born, Prof. Dr. Wolfgang Sippl, Prof. Dr. Clemens Steegborn and Prof. Dr. Mike Schutkowski

    Version of Record online : 11 AUG 2014, DOI: 10.1002/ange.201402679

  14. Chemical Probing of the Human Sirtuin 5 Active Site Reveals Its Substrate Acyl Specificity and Peptide-Based Inhibitors

    Angewandte Chemie International Edition

    Volume 53, Issue 40, September 26, 2014, Pages: 10728–10732, Claudia Roessler, Theresa Nowak, Martin Pannek, Dr. Melanie Gertz, Giang T. T. Nguyen, Michael Scharfe, Dr. Ilona Born, Prof. Dr. Wolfgang Sippl, Prof. Dr. Clemens Steegborn and Prof. Dr. Mike Schutkowski

    Version of Record online : 11 AUG 2014, DOI: 10.1002/anie.201402679

  15. The sirtuins: Markers of metabolic health

    Molecular Nutrition & Food Research

    Volume 60, Issue 1, January 2016, Pages: 79–91, Jeffrey D. Covington and Sudip Bajpeyi

    Version of Record online : 7 DEC 2015, DOI: 10.1002/mnfr.201500340

  16. You have full text access to this OnlineOpen article
    A Fluorescent Probe for Imaging Sirtuin Activity in Living Cells, Based on One-Step Cleavage of the Dabcyl Quencher

    ChemBioChem

    Volume 17, Issue 20, October 17, 2016, Pages: 1961–1967, Dr. Mitsuyasu Kawaguchi, Shohei Ikegawa, Dr. Naoya Ieda and Prof. Dr. Hidehiko Nakagawa

    Version of Record online : 9 SEP 2016, DOI: 10.1002/cbic.201600374

  17. Effects of Aging and Cardiovascular Disease Risk Factors on the Expression of Sirtuins in the Human Corpus Cavernosum

    The Journal of Sexual Medicine

    Volume 12, Issue 11, November 2015, Pages: 2141–2152, Margarida Freitas, Adriana R. Rodrigues, Nuno Tomada, João Fonseca, Alexandre Magalhães, Alexandra M. Gouveia and Delminda Neves

    Version of Record online : 9 NOV 2015, DOI: 10.1111/jsm.13035

  18. You have free access to this content
    SIRT6 in DNA repair, metabolism and ageing

    Journal of Internal Medicine

    Volume 263, Issue 2, February 2008, Pages: 128–141, D. B. Lombard, B. Schwer, F. W. Alt and R. Mostoslavsky

    Version of Record online : 21 JAN 2008, DOI: 10.1111/j.1365-2796.2007.01902.x

  19. Structures of human sirtuin 3 complexes with ADP-ribose and with carba-NAD+ and SRT1720: binding details and inhibition mechanism

    Acta Crystallographica Section D

    Volume 69, Issue 8, August 2013, Pages: 1423–1432, Giang Thi Tuyet Nguyen, Susanne Schaefer, Melanie Gertz, Michael Weyand and Clemens Steegborn

    DOI: 10.1107/S0907444913015448

  20. Studies of the Binding of Modest Modulators of the Human Enzyme, Sirtuin 6, by STD NMR

    ChemBioChem

    Volume 18, Issue 10, May 18, 2017, Pages: 931–940, Beatriz E. Bolívar and Prof. John T. Welch

    Version of Record online : 18 APR 2017, DOI: 10.1002/cbic.201600655