Search Results

There are 7371 results for: content related to: Uridine diphosphate glucuronosyl transferase 1A1 promoter polymorphism predicts the risk of gastrointestinal toxicity and fatigue induced by irinotecan-based chemotherapy

  1. UGT1A1 genotype and irinotecan therapy: general review and implementation in routine practice

    Fundamental & Clinical Pharmacology

    Volume 29, Issue 3, June 2015, Pages: 219–237, Marie-Christine Etienne-Grimaldi, Jean-Christophe Boyer, Fabienne Thomas, Sylvie Quaranta, Nicolas Picard, Marie-Anne Loriot, Céline Narjoz, Delphine Poncet, Marie-Claude Gagnieu, Cécile Ged, Franck Broly, Valérie Le Morvan, Régis Bouquié, Marie-Pierre Gaub, Laurent Philibert, François Ghiringhelli, Chantal Le Guellec and Collective work by the Groupe de Pharmacologie Clinique Oncologique (GPCO-Unicancer) and the French Réseau National de Pharmacogénétique Hospitalière (RNPGx)

    Version of Record online : 4 MAY 2015, DOI: 10.1111/fcp.12117

  2. You have full text access to this Open Access content
    Pharmacogenetic impact of polymorphisms in the coding region of the UGT1A1 gene on SN-38 glucuronidation in Japanese patients with cancer

    Cancer Science

    Volume 97, Issue 11, November 2006, Pages: 1255–1259, Kazuhiro Araki, Ken-ichi Fujita, Yuichi Ando, Fumio Nagashima, Wataru Yamamoto, Hisashi Endo, Toshimichi Miya, Keiji Kodama, Masaru Narabayashi and Yasutsuna Sasaki

    Version of Record online : 12 SEP 2006, DOI: 10.1111/j.1349-7006.2006.00321.x

  3. You have free access to this content
    UGT1A1*28 polymorphism predicts irinotecan-induced severe toxicities without affecting treatment outcome and survival in patients with metastatic colorectal carcinoma

    Cancer

    Volume 112, Issue 9, 1 May 2008, Pages: 1932–1940, Chun-Yu Liu, Po-Min Chen, Tzeon-Jye Chiou, Jin-Hwang Liu, Jen-Kou Lin, Tzu-Chen Lin, Wei-Shone Chen, Jeng-Kae Jiang, Huann-Sheng Wang and Wei-Shu Wang

    Version of Record online : 25 FEB 2008, DOI: 10.1002/cncr.23370

  4. The Role of SN-38 Exposure, UGT1A1*28 Polymorphism, and Baseline Bilirubin Level in Predicting Severe Irinotecan Toxicity

    The Journal of Clinical Pharmacology

    Volume 47, Issue 1, January 2007, Pages: 78–86, Dr Roshni P. Ramchandani, Dr Yaning Wang, Dr Brian P. Booth, Dr Amna Ibrahim, Dr John R. Johnson, Dr Atiqur Rahman, Dr Mehul Mehta, Dr Federico Innocenti, Dr Mark J. Ratain and Dr Jogarao V. S. Gobburu

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270006295060

  5. You have full text access to this Open Access content
    UGT1A1*6,1A7*3, and 1A9*22 genotypes predict severe neutropenia in FOLFIRI-treated metastatic colorectal cancer in two prospective studies in Japan

    Cancer Science

    Volume 104, Issue 12, December 2013, Pages: 1662–1669, Shoichi Hazama, Hideyuki Mishima, Ryouichi Tsunedomi, Yusuke Okuyama, Takeshi Kato, Ken-ichi Takahashi, Hiroshi Nozawa, Hideaki Ando, Michiya Kobayashi, Hiroyoshi Takemoto, Naoki Nagata, Shinsuke Kanekiyo, Yuka Inoue, Yoshihiko Hamamoto, Yusuke Fujita, Yuji Hinoda, Naoko Okayama, Koji Oba, Jun-ichi Sakamoto and Masaaki Oka

    Version of Record online : 27 OCT 2013, DOI: 10.1111/cas.12283

  6. You have full text access to this OnlineOpen article
    Cisplatin combined with irinotecan or etoposide for untreated extensive-stage small cell lung cancer: A multicenter randomized controlled clinical trial

    Thoracic Cancer

    Volume 6, Issue 6, November 2015, Pages: 785–791, Yuankai Shi, Yi Hu, Xingsheng Hu, Xue Li, Lin Lin and Xiaohong Han

    Version of Record online : 20 AUG 2015, DOI: 10.1111/1759-7714.12303

  7. You have full text access to this Open Access content
    Genotype-directed, dose-finding study of irinotecan in cancer patients with UGT1A1*28 and/or UGT1A1*6 polymorphisms

    Cancer Science

    Volume 102, Issue 10, October 2011, Pages: 1868–1873, Taroh Satoh, Takashi Ura, Yasuhide Yamada, Kentaro Yamazaki, Toshimasa Tsujinaka, Masaki Munakata, Tomohiro Nishina, Shu Okamura, Taito Esaki, Yasutsuna Sasaki, Wasaburo Koizumi, Yoshihiro Kakeji, Naoki Ishizuka, Ichinosuke Hyodo and Yuh Sakata

    Version of Record online : 12 AUG 2011, DOI: 10.1111/j.1349-7006.2011.02030.x

  8. You have full text access to this OnlineOpen article
    Prospective study of the UGT1A1*27 gene polymorphism during irinotecan therapy in patients with lung cancer: Results of Lung Oncology Group in Kyusyu (LOGIK1004B)

    Thoracic Cancer

    Minoru Fukuda, Takayuki Suetsugu, Midori Shimada, Takeshi Kitazaki, Kohji Hashiguchi, Junji Kishimoto, Taishi Harada, Takashi Seto, Noriyuki Ebi, Koichi Takayama, Kenji Sugio, Hiroshi Semba, Yoichi Nakanishi and Yukito Ichinose

    Version of Record online : 11 MAY 2016, DOI: 10.1111/1759-7714.12360

  9. Pharmacokinetics of Raltegravir in Individuals With UGT1A1 Polymorphisms

    Clinical Pharmacology & Therapeutics

    Volume 85, Issue 6, June 2009, Pages: 623–627, LA Wenning, AS Petry, JT Kost, B Jin, SA Breidinger, I DeLepeleire, EJ Carlini, S Young, T Rushmore, F Wagner, NM Lunde, F Bieberdorf, H Greenberg, JA Stone, JA Wagner and M Iwamoto

    Version of Record online : 11 MAR 2009, DOI: 10.1038/clpt.2009.12

  10. UDP-Glucuronosyltransferases: Pharmacogenetics, Functional Characterization, and Clinical Relevance

    Standard Article

    Encyclopedia of Drug Metabolism and Interactions

    Robert S. Foti and Michael B. Fisher

    Published Online : 31 JAN 2012, DOI: 10.1002/9780470921920.edm015

  11. Influence of Genetic Variants in UGT1A1 and UGT1A9 on the In Vivo Glucuronidation of SN-38

    The Journal of Clinical Pharmacology

    Volume 44, Issue 8, August 2004, Pages: 854–860, Dr Luca Paoluzzi, Mr Arun S. Singh, Dr Douglas K. Price, Dr Romano Danesi, Dr Ron H. J. Mathijssen, Dr Jaap Verweij, Dr William D. Figg and Dr Alex Sparreboom

    Version of Record online : 8 MAR 2013, DOI: 10.1177/0091270004267159

  12. You have free access to this content
    Gilbert syndrome redefined: A complex genetic haplotype influences the regulation of glucuronidation

    Hepatology

    Volume 55, Issue 6, June 2012, Pages: 1912–1921, Ursula Ehmer, Sandra Kalthoff, Bastian Fakundiny, Brigitte Pabst, Nicole Freiberg, Ronald Naumann, Michael P. Manns and Christian P. Strassburg

    Version of Record online : 23 APR 2012, DOI: 10.1002/hep.25561

  13. PhRMA White Paper on ADME Pharmacogenomics

    The Journal of Clinical Pharmacology

    Volume 48, Issue 7, July 2008, Pages: 849–889, Dr J. Andrew Williams, Dr Tommy Andersson, Dr Tommy B. Andersson, Dr Rebecca Blanchard, Dr Martin Otto Behm, Dr Nadine Cohen, Dr Timi Edeki, Dr Monique Franc, Dr Kathleen M. Hillgren, Dr Keith J. Johnson, Dr David A. Katz, Dr Mark N. Milton, Dr Bernard P. Murray, Dr Joseph W. Polli, Dr Deb Ricci, Dr Lisa A. Shipley, Dr Subrahmanyam Vangala and Dr Steven A. Wrighton

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270008319329

  14. You have full text access to this Open Access content
    Role of UGT1A1*6, UGT1A1*28 and ABCG2 c.421C>A polymorphisms in irinotecan-induced neutropenia in Asian cancer patients

    Cancer Science

    Volume 98, Issue 9, September 2007, Pages: 1461–1467, Srinivasa Rao Jada, Robert Lim, Chiung Ing Wong, Xiaochen Shu, Soo Chin Lee, Qingyu Zhou, Boon Cher Goh and Balram Chowbay

    Version of Record online : 11 JUL 2007, DOI: 10.1111/j.1349-7006.2007.00541.x

  15. You have free access to this content
    Regulation of the UGT1A1 bilirubin-conjugating pathway: Role of a new splicing event at the UGT1A locus

    Hepatology

    Volume 45, Issue 1, January 2007, Pages: 128–138, Eric Lévesque, Hugo Girard, Kim Journault, Johanie Lépine and Chantal Guillemette

    Version of Record online : 22 DEC 2006, DOI: 10.1002/hep.21464

  16. Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism

    Clinical Pharmacology & Therapeutics

    Volume 65, Issue 5, May 1999, Pages: 576–582, Lalitha Iyer, Diana Hall, Soma Das, Melissa A. Mortell, Jacqueline Ramírez, Sarang Kim, Anna Di Rienzo and Mark J. Ratain

    Version of Record online : 13 MAY 1999, DOI: 10.1016/S0009-9236(99)70078-0

  17. Clinical Pharmacology Profile of Raltegravir, an HIV-1 Integrase Strand Transfer Inhibitor

    The Journal of Clinical Pharmacology

    Volume 51, Issue 10, October 2011, Pages: 1376–1402, Diana M. Brainard, Larissa A. Wenning, Julie A. Stone, John A. Wagner and Marian Iwamoto

    Version of Record online : 8 MAR 2013, DOI: 10.1177/0091270010387428

  18. You have free access to this content
    First-pass metabolism via UDP-glucuronosyltransferase: a barrier to oral bioavailability of phenolics

    Journal of Pharmaceutical Sciences

    Volume 100, Issue 9, September 2011, Pages: 3655–3681, Baojian Wu, Kaustubh Kulkarni, Sumit Basu, Shuxing Zhang and Ming Hu

    Version of Record online : 11 APR 2011, DOI: 10.1002/jps.22568

  19. You have full text access to this OnlineOpen article
    Impact of UGT1A1 genotype upon toxicities of combination with low-dose irinotecan plus platinum

    Asia-Pacific Journal of Clinical Oncology

    Volume 12, Issue 2, June 2016, Pages: 115–124, Masashi Takano, Kaichiro Yamamoto, Tsutomu Tabata, Yuji Minegishi, Takuma Yokoyama, Eiji Hirata, Takeshi Ikeda, Muneaki Shimada, Kouzo Yamada, Satoshi Morita, Yuichi Ando, Koji Hirata, Masahiro Sugihara, Toru Sugiyama, Yasuo Ohashi and Yuh Sakata

    Version of Record online : 10 FEB 2016, DOI: 10.1111/ajco.12453

  20. You have full text access to this OnlineOpen article
    Utility of Pretreatment Bilirubin Level and UGT1A1 Polymorphisms in Multivariate Predictive Models of Neutropenia Associated with Irinotecan Treatment in Previously Untreated Patients with Colorectal Cancer

    Archives of Drug Information

    Volume 1, Issue 3, December 2008, Pages: 97–106, Luis Parodi, Eve Pickering, Laura A. Cisar, Doug Lee and Raoudha Soufi-Mahjoubi

    Version of Record online : 3 OCT 2008, DOI: 10.1111/j.1753-5174.2008.00014.x