Search Results

There are 4721 results for: content related to: Microsatellite instability, MLH1 promoter methylation, and BRAF mutation analysis in sporadic colorectal cancers of different ethnic groups in Israel

  1. Prevalence of somatic mutl homolog 1 promoter hypermethylation in Lynch syndrome colorectal cancer

    Cancer

    Leticia Moreira, Jenifer Muñoz, Míriam Cuatrecasas, Isabel Quintanilla, Maria Liz Leoz, Sabela Carballal, Teresa Ocaña, María López-Cerón, Maria Pellise, Sergi Castellví-Bel, Rodrigo Jover, Montserrat Andreu, Angel Carracedo, Rosa Maria Xicola, Xavier Llor, Clement Richard Boland, Ajay Goel, Antoni Castells and Francesc Balaguer

    Article first published online : 29 DEC 2014, DOI: 10.1002/cncr.29190

  2. MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes

    The Journal of Pathology

    Volume 229, Issue 1, January 2013, Pages: 99–110, Lawrence A Donehower, Chad J Creighton, Nikolaus Schultz, Eve Shinbrot, Kyle Chang, Preethi H Gunaratne, Donna Muzny, Chris Sander, Stanley R Hamilton, Richard A Gibbs and David Wheeler

    Article first published online : 17 DEC 2012, DOI: 10.1002/path.4087

  3. Tumours from MSH2 mutation carriers show loss of MSH2 expression but many tumours from MLH1 mutation carriers exhibit weak positive MLH1 staining

    The Journal of Pathology

    Volume 207, Issue 4, December 2005, Pages: 385–395, Elisabeth Mangold, Constanze Pagenstecher, Waltraut Friedl, Hans-Peter Fischer, Sabine Merkelbach-Bruse, Maike Ohlendorf, Nicolaus Friedrichs, Stefan Aretz, Reinhard Buettner, Peter Propping and Micaela Mathiak

    Article first published online : 10 OCT 2005, DOI: 10.1002/path.1858

  4. Evidence of constitutional MLH1 epimutation associated to transgenerational inheritance of cancer susceptibility

    Human Mutation

    Volume 33, Issue 1, January 2012, Pages: 180–188, Michel Crépin, Marie-Claire Dieu, Sophie Lejeune, Fabienne Escande, Denis Boidin, Nicole Porchet, Gilles Morin, Sylvie Manouvrier, Michèle Mathieu and Marie-Pierre Buisine

    Article first published online : 31 OCT 2011, DOI: 10.1002/humu.21617

  5. Coexisting somatic promoter hypermethylation and pathogenic MLH1 germline mutation in Lynch syndrome

    The Journal of Pathology

    Volume 214, Issue 1, January 2008, Pages: 10–16, N Rahner, N Friedrichs, V Steinke, S Aretz, W Friedl, R Buettner, E Mangold, P Propping and C Walldorf

    Article first published online : 31 OCT 2007, DOI: 10.1002/path.2263

  6. You have free access to this content
    Evidence for heritable predisposition to epigenetic silencing of MLH1

    International Journal of Cancer

    Volume 120, Issue 8, 15 April 2007, Pages: 1684–1688, Huiping Chen, Nicholas P. Taylor, Kaisa M. Sotamaa, David G. Mutch, Matthew A. Powell, Amy P. Schmidt, Sheng Feng, Heather L. Hampel, Albert de la Chapelle and Paul J. Goodfellow

    Article first published online : 17 JAN 2007, DOI: 10.1002/ijc.22406

  7. Genetic Testing for Hereditary Nonpolyposis Colorectal Cancer (HNPCC)

    Unit

    Current Protocols in Human Genetics

    10:10.12.1–10.12.28

    Madhuri R. Hegde and Benjamin B. Roa

    Published Online : 1 APR 2009, DOI: 10.1002/0471142905.hg1012s61

  8. Identification of new cases of early-onset colorectal cancer with an MLH1 epimutation in an ethnically diverse South African cohort

    Clinical Genetics

    Volume 80, Issue 5, November 2011, Pages: 428–434, MP Hitchins, SE Owens, C-T Kwok, G Godsmark, UF Algar and RS Ramesar

    Article first published online : 4 MAY 2011, DOI: 10.1111/j.1399-0004.2011.01660.x

  9. Accelerated growth of intestinal tumours after radiation exposure in Mlh1-knockout mice: evaluation of the late effect of radiation on a mouse model of HNPCC

    International Journal of Experimental Pathology

    Volume 87, Issue 2, April 2006, Pages: 89–99, Yutaka Tokairin, Shizuko Kakinuma, Masami Arai, Mayumi Nishimura, Mieko Okamoto, Eisaku Ito, Makoto Akashi, Yoshio Miki, Tatsuyuki Kawano, Takehisa Iwai and Yoshiya Shimada

    Article first published online : 28 MAR 2006, DOI: 10.1111/j.0959-9673.2006.00464.x

  10. You have free access to this content
    De novo constitutional MLH1 epimutations confer early-onset colorectal cancer in two new sporadic Lynch syndrome cases, with derivation of the epimutation on the paternal allele in one

    International Journal of Cancer

    Volume 128, Issue 4, 15 February 2011, Pages: 869–878, Ajay Goel, Thuy-Phuong Nguyen, Hon-Chiu E. Leung, Takeshi Nagasaka, Jennifer Rhees, Erin Hotchkiss, Mildred Arnold, Pia Banerji, Minoru Koi, Chau-To Kwok, Deborah Packham, Lara Lipton, C. Richard Boland, Robyn L. Ward and Megan P. Hitchins

    Article first published online : 27 APR 2010, DOI: 10.1002/ijc.25422

  11. You have free access to this content
    Diethylstilbestrol effects and lymphomagenesis in Mlh1-deficient mice

    International Journal of Cancer

    Volume 115, Issue 4, 1 July 2005, Pages: 666–669, Omar Kabbarah, Andrea K. Sotelo, Mary Ann Mallon, Erin L. Winkeler, Ming-Yu Fan, John D. Pfeifer, Darryl Shibata, David H. Gutmann and Paul J. Goodfellow

    Article first published online : 7 FEB 2005, DOI: 10.1002/ijc.20918

  12. Germ line MLH1 and MSH2 mutations in Taiwanese Lynch syndrome families: characterization of a founder genomic mutation in the MLH1 gene

    Clinical Genetics

    Volume 75, Issue 4, April 2009, Pages: 334–345, R Tang, C Hsiung, J-Y Wang, C-H Lai, H-T Chien, L-L Chiu, C-T Liu, H-H Chen, H-M Wang, S-X Chen, L-L Hsieh and the TCOG HNPCC Consortium

    Article first published online : 15 APR 2009, DOI: 10.1111/j.1399-0004.2009.01162.x

  13. Comprehensive functional assessment of MLH1 variants of unknown significance

    Human Mutation

    Volume 33, Issue 11, November 2012, Pages: 1576–1588, Ester Borràs, Marta Pineda, Angela Brieger, Inga Hinrichsen, Carolina Gómez, Matilde Navarro, Judit Balmaña, Teresa Ramón y Cajal, Asunción Torres, Joan Brunet, Ignacio Blanco, Guido Plotz, Conxi Lázaro and Gabriel Capellá

    Article first published online : 12 JUL 2012, DOI: 10.1002/humu.22142

    Corrected by:

    Erratum: Comprehensive Functional Assessment of MLH1 Variants of Unknown Significance

    Vol. 34, Issue 1, 274, Article first published online: 27 NOV 2012

  14. You have free access to this content
    Analysis of telomere dynamics in peripheral blood cells from patients with Lynch syndrome

    Cancer

    Volume 117, Issue 18, 15 September 2011, Pages: 4325–4335, Cristina Bozzao, Patrizia Lastella, Maurizio Ponz de Leon, Monica Pedroni, Carmela Di Gregorio, Francesco D. D'Ovidio, Nicoletta Resta, Fernando Prete, Ginevra Guanti and Alessandro Stella

    Article first published online : 8 MAR 2011, DOI: 10.1002/cncr.26022

  15. You have free access to this content
    Evidence for the role of aberrant DNA methylation in the pathogenesis of Lynch syndrome adenomas

    International Journal of Cancer

    Volume 120, Issue 9, 1 May 2007, Pages: 1922–1929, Andrew Kaz, Young-Ho Kim, Slavomir Dzieciatkowski, Henry Lynch, Patrice Watson, Mary Kay Washington, Li Lin and William M. Grady

    Article first published online : 2 FEB 2007, DOI: 10.1002/ijc.22544

  16. You have full text access to this Open Access content
    A review on the molecular diagnostics of Lynch syndrome: a central role for the pathology laboratory

    Journal of Cellular and Molecular Medicine

    Volume 14, Issue 1-2, January-February 2010, Pages: 181–197, Margot G.F. Van Lier, Anja Wagner, Monique E. Van Leerdam, Katharina Biermann, Ernst J. Kuipers, Ewout W. Steyerberg, Hendrikus Jan Dubbink and Winand N.M. Dinjens

    Article first published online : 19 NOV 2009, DOI: 10.1111/j.1582-4934.2009.00977.x

  17. The MLH1 −93 G>A promoter polymorphism and genetic and epigenetic alterations in colon cancer

    Genes, Chromosomes and Cancer

    Volume 47, Issue 10, October 2008, Pages: 835–844, Wade S. Samowitz, Karen Curtin, Roger K. Wolff, Hans Albertsen, Carol Sweeney, Bette J. Caan, Cornelia M. Ulrich, John D. Potter and Martha L. Slattery

    Article first published online : 9 JUL 2008, DOI: 10.1002/gcc.20584

  18. Germline MSH2 and MLH1 mutational spectrum including large rearrangements in HNPCC families from Poland (update study)

    Clinical Genetics

    Volume 69, Issue 1, January 2006, Pages: 40–47, G Kurzawski, J Suchy, M Lener, E Kłujszo-Grabowska, J Kładny, K Safranow, K Jakubowska, A Jakubowska, T Huzarski, T Byrski, T Dębniak, C Cybulski, J Gronwald, O Oszurek, D Oszutowska, E Kowalska, S Góźdź, S Niepsuj, R Słomski, A Pławski, A Łącka-Wojciechowska, A Rozmiarek, Ł Fiszer-Maliszewska, M Bębenek, D Sorokin, MM Sąsiadek, A Stembalska, Z Grzebieniak, E Kilar, M Stawicka, D Godlewski, P Richter, I Brożek, B Wysocka, J Limon, A Jawień, Z Banaszkiewicz, H Janiszewska, J Kowalczyk, D Czudowska, RJ Scott and J Lubiński

    Article first published online : 13 DEC 2005, DOI: 10.1111/j.1399-0004.2006.00550.x

  19. Redundant DNA methylation in colorectal cancers of Lynch-syndrome patients

    Genes, Chromosomes and Cancer

    Volume 47, Issue 10, October 2008, Pages: 906–914, Aster Alemayehu, Katarina Sebova and Ivana Fridrichova

    Article first published online : 10 JUL 2008, DOI: 10.1002/gcc.20586

  20. Variable MLH1 promoter methylation patterns in endometrial carcinomas of endometrioid subtype lacking DNA mismatch repair

    International Journal of Gynecological Cancer

    Volume 15, Issue 6, November 2005, Pages: 1089–1096, K.E. HELMLE, C.J. OTTO, G. CONSTANTINESCU, L.H. HONORE and S.E. ANDREW

    Article first published online : 17 NOV 2005, DOI: 10.1111/j.1525-1438.2005.00266.x