Search Results

There are 10877 results for: content related to: Mechanisms of constitutive activation of Janus kinase 2-V617F revealed at the atomic level through molecular dynamics simulations

  1. You have free access to this content
    Differential biological activity of disease-associated JAK2 mutants

    FEBS Letters

    Volume 585, Issue 7, April 06, 2011, Pages: 1007–1013, Haiying Zou, Dongqing Yan and Golam Mohi

    Version of Record online : 4 MAR 2011, DOI: 10.1016/j.febslet.2011.02.032

  2. You have free access to this content
    Loss of the JAK2 intramolecular auto-inhibition mechanism is predicted by structural modelling of a novel exon 12 insertion mutation in a case of idiopathic erythrocytosis

    British Journal of Haematology

    Volume 142, Issue 6, September 2008, Pages: 986–990, Elena Albiero, Domenico Madeo, Marco Ruggeri, Martina Bernardi, Alejandro Giorgetti and Francesco Rodeghiero

    Version of Record online : 30 JUL 2008, DOI: 10.1111/j.1365-2141.2008.07180.x

  3. You have free access to this content
    The role of Janus kinases in haemopoiesis and haematological malignancy

    British Journal of Haematology

    Volume 134, Issue 4, August 2006, Pages: 366–384, Asim Khwaja

    Version of Record online : 5 JUL 2006, DOI: 10.1111/j.1365-2141.2006.06206.x

  4. Stereoselective C-glycosidation of unprotected D-glycals with trimethylsilyl cyanide


    Volume 15, Issue 1, 2003, Pages: 10–16, Masahiko Hayashi, Hirotoshi Kawabata and Shu-Zo Nakayama

    Version of Record online : 20 NOV 2002, DOI: 10.1002/chir.10146

  5. Somatic Mutations in Polycythaemia Vera and Other Philadelphia Chromosome Negative Myeloproliferative Neoplasms

    Standard Article


    Lukasz P Gondek and Jerry L Spivak

    Published Online : 17 DEC 2012, DOI: 10.1002/9780470015902.a0024249

  6. You have full text access to this Open Access content
    The JAK kinase inhibitor CP-690,550 supresses the growth of human polycythemia vera cells carrying the JAK2V617F mutation

    Cancer Science

    Volume 99, Issue 6, June 2008, Pages: 1265–1273, Taghi Manshouri, Alfonso Quintás-Cardama, Roberto H. Nussenzveig, Amos Gaikwad, Zeev Estrov, Josef Prchal, Jorge E. Cortes, Hagop M. Kantarjian and Srdan Verstovsek

    Version of Record online : 28 JUN 2008, DOI: 10.1111/j.1349-7006.2008.00817.x

  7. You have free access to this content
    JAK2 and genomic instability in the myeloproliferative neoplasms: A case of the chicken or the egg?

    American Journal of Hematology

    Volume 87, Issue 11, November 2012, Pages: 1028–1036, Linda M. Scott and Vivienne I. Rebel

    Version of Record online : 28 MAY 2012, DOI: 10.1002/ajh.23243

  8. Update on the impact of the JAK2 mutation on signalling pathways in myeloproliferative disorders

    European Journal of Haematology

    Volume 79, Issue s68, October 2007, Pages: 5–8, Radek Skoda

    Version of Record online : 23 AUG 2007, DOI: 10.1111/j.1600-0609.2007.00935.x

  9. You have full text access to this Open Access content
    Molecular drug targets in myeloproliferative neoplasms: mutant ABL1, JAK2, MPL, KIT, PDGFRA, PDGFRB and FGFR1

    Journal of Cellular and Molecular Medicine

    Volume 13, Issue 2, February 2009, Pages: 215–237, Ayalew Tefferi

    Version of Record online : 23 OCT 2008, DOI: 10.1111/j.1582-4934.2008.00559.x

  10. You have full text access to this Open Access content
    Perspectives for the use of structural information and chemical genetics to develop inhibitors of Janus kinases

    Journal of Cellular and Molecular Medicine

    Volume 14, Issue 3, March 2010, Pages: 504–527, Claude Haan, Iris Behrmann and Serge Haan

    Version of Record online : 28 JAN 2010, DOI: 10.1111/j.1582-4934.2010.01018.x

  11. You have free access to this content
    Molecular diagnosis of the myeloproliferative neoplasms: UK guidelines for the detection of JAK2 V617F and other relevant mutations

    British Journal of Haematology

    Volume 160, Issue 1, January 2013, Pages: 25–34, Anthony J. Bench, Helen E. White, Letizia Foroni, Anna L. Godfrey, Gareth Gerrard, Susanna Akiki, Abida Awan, Ian Carter, Andrea Goday-Fernandez, Stephen E. Langabeer, Tim Clench, Jordan Clark, Paul A. Evans, David Grimwade, Anna Schuh, Mary F. McMullin, Anthony R. Green, Claire N. Harrison and Nicholas C. P. Cross

    Version of Record online : 11 OCT 2012, DOI: 10.1111/bjh.12075

  12. You have free access to this content
    Advances in Understanding and Management of Myeloproliferative Neoplasms

    CA: A Cancer Journal for Clinicians

    Volume 59, Issue 3, May/June 2009, Pages: 171–191, Alessandro M. Vannucchi, Paola Guglielmelli and Ayalew Tefferi

    Version of Record online : 16 APR 2009, DOI: 10.3322/caac.20009

  13. You have free access to this content
    Nuclear JAK2: Form and Function in Cancer

    The Anatomical Record

    Volume 294, Issue 9, September 2011, Pages: 1446–1459, Cui-Juan Qian, Jun Yao and Jian-Min Si

    Version of Record online : 1 AUG 2011, DOI: 10.1002/ar.21443

  14. You have free access to this content
    Impact of peptidoglycan O-acetylation on autolytic activities of the Enterococcus faecalis N-acetylglucosaminidase AtlA and N-acetylmuramidase AtlB

    FEBS Letters

    Volume 583, Issue 18, September 17, 2009, Pages: 3033–3038, Aurélie Emirian, Sophie Fromentin, Catherine Eckert, Françoise Chau, Lionel Dubost, Muriel Delepierre, Laurent Gutmann, Michel Arthur and Stéphane Mesnage

    Version of Record online : 15 AUG 2009, DOI: 10.1016/j.febslet.2009.08.010

  15. Janus kinases in immune cell signaling

    Immunological Reviews

    Volume 228, Issue 1, March 2009, Pages: 273–287, Kamran Ghoreschi, Arian Laurence and John J. O’Shea

    Version of Record online : 6 MAR 2009, DOI: 10.1111/j.1600-065X.2008.00754.x

  16. JAK/STAT Signalling and Haematological Malignancies

    Standard Article


    Stefan N Constantinescu and William Vainchenker

    Published Online : 15 OCT 2015, DOI: 10.1002/9780470015902.a0024988

  17. You have free access to this content
    Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes

    The EMBO Journal

    Volume 17, Issue 18, September 15, 1998, Pages: 5321–5333, Juerg Schwaller, Julie Frantsve, Jon Aster, Ifor R. Williams, Michael H. Tomasson, Theodora S. Ross, Pieter Peeters, Luc Van Rompaey, Richard A. Van Etten, Robert Ilaria Jr, Peter Marynen and D.Gary Gilliland

    Version of Record online : 15 SEP 1998, DOI: 10.1093/emboj/17.18.5321

  18. You have free access to this content
    The V617F mutation in Jak2 is not found in childhood acute lymphoblastic leukaemia

    British Journal of Haematology

    Volume 130, Issue 6, September 2005, Pages: 964–965, Sarina Sulong, Marian Case, Lynne Minto, Bridget Wilkins, Andy Hall and Julie Irving

    Version of Record online : 25 AUG 2005, DOI: 10.1111/j.1365-2141.2005.05697.x

  19. You have free access to this content
    Horizontal transfer of tet(M) and erm(B) resistance plasmids from food strains of Lactobacillus plantarum to Enterococcus faecalis JH2-2 in the gastrointestinal tract of gnotobiotic rats

    FEMS Microbiology Ecology

    Volume 59, Issue 1, January 2007, Pages: 158–166, Louise Jacobsen, Andrea Wilcks, Karin Hammer, Geert Huys, Dirk Gevers and Sigrid Rita Andersen

    Version of Record online : 2 OCT 2006, DOI: 10.1111/j.1574-6941.2006.00212.x

  20. You have free access to this content
    Identification and characterization of genes encoding sex pheromone cAM373 activity in Enterococcus faecalis and Staphylococcus aureus

    Molecular Microbiology

    Volume 44, Issue 3, May 2002, Pages: 803–817, Susan E. Flannagan and Don B. Clewell

    Version of Record online : 7 MAY 2002, DOI: 10.1046/j.1365-2958.2002.02922.x