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There are 16344 results for: content related to: Targeting FMS-related tyrosine kinase receptor 3 with the human immunoglobulin G1 monoclonal antibody IMC-EB10

  1. You have free access to this content
    Constitutive activation of FLT3 in acute myeloid leukaemia and its consequences for growth of 32D cells

    British Journal of Haematology

    Volume 108, Issue 2, February 2000, Pages: 322–330, Fenski, Flesch, Serve, Mizuki, Oelmann, Kratz-Albers, Kienast, Leo, Schwartz, Berdel and Serve

    Article first published online : 24 DEC 2001, DOI: 10.1046/j.1365-2141.2000.01831.x

  2. FLT3 mutation status is a predictor of early death in pediatric acute promyelocytic leukemia: A report from the Children's Oncology Group

    Pediatric Blood & Cancer

    Volume 59, Issue 4, October 2012, Pages: 662–667, Matthew A. Kutny, Barry K. Moser, Kristina Laumann, James H. Feusner, Alan Gamis, John Gregory, Richard A. Larson, Bayard L. Powell, Wendy Stock, Cheryl L. Willman, William G. Woods and Soheil Meshinchi

    Article first published online : 29 FEB 2012, DOI: 10.1002/pbc.24122

  3. You have free access to this content
    Treatment with FLT3 inhibitor in patients with FLT3-mutated acute myeloid leukemia is associated with development of secondary FLT3–tyrosine kinase domain mutations


    Volume 120, Issue 14, 15 July 2014, Pages: 2142–2149, Yesid Alvarado, Hagop M. Kantarjian, Rajyalakshmi Luthra, Farhad Ravandi, Gautam Borthakur, Guillermo Garcia-Manero, Marina Konopleva, Zeev Estrov, Michael Andreeff and Jorge E. Cortes

    Article first published online : 15 APR 2014, DOI: 10.1002/cncr.28705

  4. Diversity of the juxtamembrane and TKD1 mutations (Exons 13–15) in the FLT3 gene with regards to mutant load, sequence, length, localization, and correlation with biological data

    Genes, Chromosomes and Cancer

    Volume 51, Issue 10, October 2012, Pages: 910–924, Susanne Schnittger, Ulrike Bacher, Claudia Haferlach, Tamara Alpermann, Wolfgang Kern and Torsten Haferlach

    Article first published online : 4 JUN 2012, DOI: 10.1002/gcc.21975

  5. You have free access to this content
    FLT3 mutations in myelodysplastic syndrome and chronic myelomonocytic leukemia

    American Journal of Hematology

    Volume 88, Issue 1, January 2013, Pages: 56–59, Naval Daver, Paolo Strati, Elias Jabbour, Tapan Kadia, Raja Luthra, Sa Wang, Keyur Patel, Farhad Ravandi, Jorge Cortes, Xiao Qin Dong, Hagop Kantarjian and Guillermo Garcia-Manero

    Article first published online : 31 OCT 2012, DOI: 10.1002/ajh.23345

  6. Perspectives for therapeutic targeting of gene mutations in acute myeloid leukaemia with normal cytogenetics

    British Journal of Haematology

    Volume 170, Issue 3, August 2015, Pages: 305–322, Brunangelo Falini, Paolo Sportoletti, Lorenzo Brunetti and Maria Paola Martelli

    Article first published online : 19 APR 2015, DOI: 10.1111/bjh.13409

  7. Monitoring of FLT3 phosphorylation status and its response to drugs by flow cytometry in AML blast cells

    Hematological Oncology

    Volume 26, Issue 3, September 2008, Pages: 159–166, Tiziana Grafone, Michela Palmisano, Chiara Nicci, Alberto Maria Martelli, Ottaviani Emanuela, Sergio Storti, Michele Baccarani and Giovanni Martinelli

    Article first published online : 31 MAR 2008, DOI: 10.1002/hon.854

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    Influence of FLT3-internal tandem duplication allele burden and white blood cell count on the outcome in patients with intermediate-risk karyotype acute myeloid leukemia


    Volume 118, Issue 24, 15 December 2012, Pages: 6110–6117, Jonathan How, Jenna Sykes, Vikas Gupta, Karen W. L. Yee, Aaron D. Schimmer, Andre C. Schuh, Mark D. Minden, Suzanne Kamel-Reid and Joseph M. Brandwein

    Article first published online : 26 JUN 2012, DOI: 10.1002/cncr.27683

  9. Improvement in clinical outcome of FLT3 ITD mutated acute myeloid leukemia patients over the last one and a half decade

    American Journal of Hematology

    Volume 90, Issue 11, November 2015, Pages: 1065–1070, Talha Badar, Hagop M. Kantarjian, Graciela M. Nogueras-Gonzalez, Gautam Borthakur, Guillermo Garcia Manero, Michael Andreeff, Marina Konopleva, Tapan M. Kadia, Naval Daver, William G. Wierda, Raja Luthra, Keyur Patel, Betul Oran, Richard Champlin, Farhad Ravandi and Jorge E. Cortes

    Article first published online : 10 SEP 2015, DOI: 10.1002/ajh.24140

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    Ponatinib may overcome resistance of FLT3-ITD harbouring additional point mutations, notably the previously refractory F691I mutation

    British Journal of Haematology

    Volume 157, Issue 4, May 2012, Pages: 483–492, Elisabeth Zirm, Bärbel Spies-Weisshart, Florian Heidel, Ulf Schnetzke, Frank-Dietmar Böhmer, Andreas Hochhaus, Thomas Fischer and Sebastian Scholl

    Article first published online : 13 MAR 2012, DOI: 10.1111/j.1365-2141.2012.09085.x

  11. You have free access to this content
    Threshold levels of Flt3-ligand are required for the generation and survival of lymphoid progenitors and B-cell precursors

    European Journal of Immunology

    Volume 41, Issue 2, February 2011, Pages: 324–334, Joseph J. Dolence, Kimberly Gwin, Elena Frank and Kay L. Medina

    Article first published online : 25 JAN 2011, DOI: 10.1002/eji.201040710

  12. Tyrosine Kinase Inhibitors

    Targeting Protein Kinases for Cancer Therapy

    David J. Matthews, Mary E. Gerritsen, Pages: 435–525, 2010

    Published Online : 11 MAR 2010, DOI: 10.1002/9780470555293.ch8

  13. FLT3 Antibody-based therapy for leukemia

    Drug Development Research

    Volume 67, Issue 6, June 2006, Pages: 495–500, Yiwen Li

    Article first published online : 11 OCT 2006, DOI: 10.1002/ddr.20112

  14. Y654 of β-catenin is essential for FLT3/ITD-related tyrosine phosphorylation and nuclear localization of β-catenin

    European Journal of Haematology

    Volume 88, Issue 4, April 2012, Pages: 314–320, Tomohiro Kajiguchi, Akira Katsumi, Ryohei Tanizaki, Hitoshi Kiyoi and Tomoki Naoe

    Article first published online : 4 JAN 2012, DOI: 10.1111/j.1600-0609.2011.01738.x

  15. Interleukin-2-mediated inhibition of dendritic cell development correlates with decreased CD135 expression and increased monocyte/macrophage precursors


    Volume 143, Issue 4, December 2014, Pages: 640–650, Alan D. Guerrero, Matthew B. Dong, Yongge Zhao, Annie Lau-Kilby and Kristin V. Tarbell

    Article first published online : 10 NOV 2014, DOI: 10.1111/imm.12345

  16. Inhibition of Flt3-activating mutations does not prevent constitutive activation of ERK/Akt/STAT pathways in some AML cells: a possible cause for the limited effectiveness of monotherapy with small-molecule inhibitors

    Hematological Oncology

    Volume 25, Issue 1, March 2007, Pages: 30–37, Emilio Siendones, Nuria Barbarroja, Luis Arístides Torres, Paula Buendía, Francisco Velasco, Gabriel Dorado, Antonio Torres and Chary López-Pedrera

    Article first published online : 24 NOV 2006, DOI: 10.1002/hon.805

  17. You have full text access to this OnlineOpen article
    Calcium and Calcineurin-NFAT Signaling Regulate Granulocyte-Monocyte Progenitor Cell Cycle via Flt3-L


    Volume 32, Issue 12, December 2014, Pages: 3232–3244, Jan Fric, Clarice X.F. Lim, Alexandra Mertes, Bernett T.K. Lee, Elena Viganò, Jinmiao Chen, Francesca Zolezzi, Michael Poidinger, Anis Larbi, Herbert Strobl, Teresa Zelante and Paola Ricciardi-Castagnoli

    Article first published online : 26 NOV 2014, DOI: 10.1002/stem.1813

  18. You have free access to this content
    Early progenitor cells from human mobilized peripheral blood express low levels of the flt3 receptor, but exhibit various biological responses to flt3-L

    British Journal of Haematology

    Volume 106, Issue 2, August 1999, Pages: 357–367, Thérèse Aurran-Schleinitz, Anne-Marie Imbert, Laurent Humeau, Florence Bardin, Pierre Charbord and Christian Chabannon

    Article first published online : 5 APR 2002, DOI: 10.1046/j.1365-2141.1999.01582.x

  19. Is allogeneic transplantation really the best treatment for FLT3/ITD-positive acute myeloid leukemia? A systematic review

    Clinical Transplantation

    Volume 29, Issue 2, February 2015, Pages: 149–160, Yingying Ma, Yazhou Wu, Zhaohua Shen, Xi Zhang, Dongfeng Zeng and Peiyan Kong

    Article first published online : 2 JAN 2015, DOI: 10.1111/ctr.12495

  20. Non-Cytogenetic Markers and their Impact on Prognosis

    Leukemias: Principles and Practice of Therapy

    Eric Schafer, Donald Small, Pages: 56–76, 2011

    Published Online : 4 JAN 2011, DOI: 10.1002/9781444327359.ch5