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There are 4328 results for: content related to: A front-line window of opportunity phase 2 study of sorafenib in patients with advanced nonsmall cell lung cancer

  1. You have free access to this content
    Sorafenib relieves cell-intrinsic and cell-extrinsic inhibitions of effector T cells in tumor microenvironment to augment antitumor immunity

    International Journal of Cancer

    Volume 134, Issue 2, 15 January 2014, Pages: 319–331, Mei-Ling Chen, Bo-Shiun Yan, Wan-Chih Lu, Mei-Huei Chen, Sung-Liang Yu, Pan-Chyr Yang and Ann-Lii Cheng

    Version of Record online : 30 JUL 2013, DOI: 10.1002/ijc.28362

  2. Sorafenib induces endometrial carcinoma apoptosis by inhibiting Elk-1-dependent Mcl-1 transcription and inducing Akt/GSK3β-dependent protein degradation

    Journal of Cellular Biochemistry

    Volume 114, Issue 8, August 2013, Pages: 1819–1831, Nian-Kang Sun, Shang-Lang Huang, Ting-Chang Chang and Chuck C.-K. Chao

    Version of Record online : 11 JUN 2013, DOI: 10.1002/jcb.24530

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    Nuclear factor kappa B–mediated CD47 up-regulation promotes sorafenib resistance and its blockade synergizes the effect of sorafenib in hepatocellular carcinoma in mice

    Hepatology

    Volume 62, Issue 2, August 2015, Pages: 534–545, Jessica Lo, Eunice Yuen Ting Lau, Rachel Hiu Ha Ching, Bowie Yik Ling Cheng, Mark Kin Fai Ma, Irene Oi Lin Ng and Terence Kin Wah Lee

    Version of Record online : 3 JUN 2015, DOI: 10.1002/hep.27859

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    EGFR activation is a potential determinant of primary resistance of hepatocellular carcinoma cells to sorafenib

    International Journal of Cancer

    Volume 131, Issue 12, 15 December 2012, Pages: 2961–2969, Zakaria Ezzoukhry, Christophe Louandre, Eric Trécherel, Corinne Godin, Bruno Chauffert, Sébastien Dupont, Momar Diouf, Jean-Claude Barbare, Jean-Claude Mazière and Antoine Galmiche

    Version of Record online : 30 APR 2012, DOI: 10.1002/ijc.27604

  5. You have full text access to this Open Access content
    Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

    Journal of Cellular and Molecular Medicine

    Volume 13, Issue 8b, August 2009, Pages: 2673–2683, Hung Huynh, Van Chanh Ngo, Heng Nung Koong, Donald Poon, Su Pin Choo, Choon Hua Thng, Pierce Chow, Hock Soo Ong, Alexander Chung and Khee Chee Soo

    Version of Record online : 11 FEB 2009, DOI: 10.1111/j.1582-4934.2009.00692.x

  6. Clinical outcome of sorafenib treatment in patients with advanced hepatocellular carcinoma refractory to hepatic arterial infusion chemotherapy

    Journal of Gastroenterology and Hepatology

    Volume 28, Issue 12, December 2013, Pages: 1834–1841, Daisuke Miyaki, Hiroshi Aikata, Hiromi Kan, Hatsue Fujino, Ayako Urabe, Keiichi Masaki, Takayuki Fukuhara, Tomoki Kobayashi, Noriaki Naeshiro, Takashi Nakahara, Tomokazu Kawaoka, Akira Hiramatsu, Shoichi Takahashi, Masaki Ishikawa, Hideaki Kakizawa, Kazuo Awai and Kazuaki Chayama

    Version of Record online : 22 NOV 2013, DOI: 10.1111/jgh.12311

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    Effects of Antitumor Drug Sorafenib on Chick Embryo Development

    The Anatomical Record

    Volume 298, Issue 7, July 2015, Pages: 1271–1281, Yi-Sen Cheng, Xiao-Yu Wang, Guang Wang, Yan Li, Yue-Lei Chen, Man-li Chuai, Kenneth Ka Ho Lee, Xiao-Yan Ding and Xue-song Yang

    Version of Record online : 17 APR 2015, DOI: 10.1002/ar.23155

  8. You have full text access to this OnlineOpen article
    Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation

    International Journal of Cancer

    Volume 136, Issue 6, 15 March 2015, Pages: 1434–1444, Floris H. Groenendijk, Wouter W. Mellema, Eline van der Burg, Eva Schut, Michael Hauptmann, Hugo M. Horlings, Stefan M. Willems, Michel M. van den Heuvel, Jos Jonkers, Egbert F. Smit and René Bernards

    Version of Record online : 8 AUG 2014, DOI: 10.1002/ijc.29113

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    A new patient-focused approach to the treatment of metastatic renal cell carcinoma: establishing customized treatment options

    BJU International

    Volume 107, Issue 8, April 2011, Pages: 1190–1199, Joaquim Bellmunt, Tim Eisen, Cezary Szczylik, Peter Mulders and Camillo Porta

    Version of Record online : 15 NOV 2010, DOI: 10.1111/j.1464-410X.2010.09829.x

  10. You have full text access to this OnlineOpen article
    GRP78/Dna K Is a Target for Nexavar/Stivarga/Votrient in the Treatment of Human Malignancies, Viral Infections and Bacterial Diseases

    Journal of Cellular Physiology

    Volume 230, Issue 10, October 2015, Pages: 2552–2578, Jane L. Roberts, Mehrad Tavallai, Aida Nourbakhsh, Abigail Fidanza, Tanya Cruz-Luna, Elizabeth Smith, Paul Siembida, Pascale Plamondon, Kelly A. Cycon, Christopher D. Doern, Laurence Booth and Paul Dent

    Version of Record online : 23 JUN 2015, DOI: 10.1002/jcp.25014

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    ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21(CIP1/WAF1) in human cancer cells

    British Journal of Pharmacology

    Volume 171, Issue 13, July 2014, Pages: 3182–3195, Jingru Li, Yicheng Chen, Jiali Wan, Xin Liu, Chunrong Yu and Wenhua Li

    Version of Record online : 10 JUN 2014, DOI: 10.1111/bph.12659

  12. You have full text access to this OnlineOpen article
    FTY720 (Fingolimod) sensitizes hepatocellular carcinoma cells to sorafenib-mediated cytotoxicity

    Pharmacology Research & Perspectives

    Volume 3, Issue 5, October 2015, Dilruba Ahmed, Petra J. de Verdier, Charlotta Ryk, Oscar Lunqe, Per Stål and Jenny Flygare

    Version of Record online : 19 AUG 2015, DOI: 10.1002/prp2.171

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    Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib

    Hepatology

    Volume 56, Issue 6, December 2012, Pages: 2363–2374, Carlo Spirli, Carola M. Morell, Luigi Locatelli, Stefano Okolicsanyi, Cecilia Ferrero, Amy K. Kim, Luca Fabris, Romina Fiorotto and Mario Strazzabosco

    Version of Record online : 27 AUG 2012, DOI: 10.1002/hep.25872

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    Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal-derived factor 1 alpha/C-X-C receptor type 4 axis and myeloid differentiation antigen–positive myeloid cell infiltration in mice

    Hepatology

    Volume 59, Issue 4, April 2014, Pages: 1435–1447, Yunching Chen, Yuhui Huang, Thomas Reiberger, Annique M. Duyverman, Peigen Huang, Rekha Samuel, Lotte Hiddingh, Sylvie Roberge, Christina Koppel, Gregory Y. Lauwers, Andrew X. Zhu, Rakesh K. Jain and Dan G. Duda

    Version of Record online : 18 FEB 2014, DOI: 10.1002/hep.26790

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    Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2

    Hepatology

    Volume 50, Issue 6, December 2009, Pages: 1861–1870, Boris R. A. Blechacz, Rory L. Smoot, Steven F. Bronk, Nathan W. Werneburg, Alphonse E. Sirica and Gregory J. Gores

    Version of Record online : 5 AUG 2009, DOI: 10.1002/hep.23214

  16. Effect of treatment with branched-chain amino acids during sorafenib therapy for unresectable hepatocellular carcinoma

    Hepatology Research

    Volume 44, Issue 3, March 2014, Pages: 302–312, Haruhiko Takeda, Hiroki Nishikawa, Eriko Iguchi, Yoshiaki Ohara, Azusa Sakamoto, Sumio Saito, Norihiro Nishijima, Akihiro Nasu, Hideyuki Komekado, Ryuichi Kita, Toru Kimura and Yukio Osaki

    Version of Record online : 29 APR 2013, DOI: 10.1111/hepr.12125

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    Inhibition of doxorubicin-induced autophagy in hepatocellular carcinoma Hep3B cells by sorafenib – the role of extracellular signal-regulated kinase counteraction

    The FEBS Journal

    Volume 278, Issue 18, September 2011, Pages: 3494–3507, Irena Manov, Yulia Pollak, Rinata Broneshter and Theodore C. Iancu

    Version of Record online : 5 SEP 2011, DOI: 10.1111/j.1742-4658.2011.08271.x

  18. Nutlin-3 enhances sorafenib efficacy in renal cell carcinoma

    Molecular Carcinogenesis

    Volume 52, Issue 1, January 2013, Pages: 39–48, Rit Vatsyayan, Jyotsana Singhal, Lokesh Dalasanur Nagaprashantha, Sanjay Awasthi and Sharad S. Singhal

    Version of Record online : 17 OCT 2011, DOI: 10.1002/mc.20875

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    Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma

    International Journal of Cancer

    Volume 131, Issue 3, 1 August 2012, Pages: 548–557, Satoshi Shimizu, Tetsuo Takehara, Hayato Hikita, Takahiro Kodama, Hinako Tsunematsu, Takuya Miyagi, Atsushi Hosui, Hisashi Ishida, Tomohide Tatsumi, Tatsuya Kanto, Naoki Hiramatsu, Naonobu Fujita, Tamotsu Yoshimori and Norio Hayashi

    Version of Record online : 12 SEP 2011, DOI: 10.1002/ijc.26374

  20. Sorafenib sensitizes hepatocellular carcinoma cells to physiological apoptotic stimuli

    Journal of Cellular Physiology

    Volume 227, Issue 4, April 2012, Pages: 1319–1325, Joan Fernando, Patricia Sancho, Conrado M. Fernández-Rodriguez, José L. Lledó, Laia Caja, Jean S. Campbell, Nelson Fausto and Isabel Fabregat

    Version of Record online : 11 JAN 2012, DOI: 10.1002/jcp.22843