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There are 33634 results for: content related to: Decreased sensitivity of 17p-deleted chronic lymphocytic leukemia cells to a small molecule BCL-2 antagonist ABT-737

  1. You have free access to this content
    Chronic lymphocytic leukemia: 2015 Update on diagnosis, risk stratification, and treatment

    American Journal of Hematology

    Volume 90, Issue 5, May 2015, Pages: 446–460, Michael Hallek

    Version of Record online : 23 APR 2015, DOI: 10.1002/ajh.23979

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    A new hope: novel therapeutic approaches to treatment of chronic lymphocytic leukaemia with defects in TP53

    British Journal of Haematology

    Volume 167, Issue 2, October 2014, Pages: 149–161, Polina Shindiapina, Jennifer R. Brown and Alexey V. Danilov

    Version of Record online : 20 JUL 2014, DOI: 10.1111/bjh.13042

  3. Bcl-2 phosphorylation confers resistance on chronic lymphocytic leukaemia cells to the BH3 mimetics ABT-737, ABT-263 and ABT-199 by impeding direct binding

    British Journal of Pharmacology

    Volume 173, Issue 3, February 2016, Pages: 471–483, Ting Song, Gaobo Chai, Yubo Liu, Xiaoyan Yu, Ziqian Wang and Zhichao Zhang

    Version of Record online : 16 JAN 2016, DOI: 10.1111/bph.13370

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    Mitoxantrone in combination with an inhibitor of DNA-dependent protein kinase: a potential therapy for high risk B-cell chronic lymphocytic leukaemia

    British Journal of Haematology

    Volume 152, Issue 1, January 2011, Pages: 61–71, Sarah L. Elliott, Clark Crawford, Evan Mulligan, Geoffrey Summerfield, Paula Newton, Jonathan Wallis, Tryfonia Mainou-Fowler, Paul Evans, Clare Bedwell, Barbara W. Durkacz and Elaine Willmore

    Version of Record online : 18 NOV 2010, DOI: 10.1111/j.1365-2141.2010.08425.x

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    Impact of trisomy 12, del(13q), del(17p), and del(11q) on the immunophenotype, DNA ploidy status, and proliferative rate of leukemic B-cells in chronic lymphocytic leukemia

    Cytometry Part B: Clinical Cytometry

    Volume 74B, Issue 3, May 2008, Pages: 139–149, Sandra Quijano, Antonio López, Ana Rasillo, José María Sayagués, Susana Barrena, Maria Luz Sánchez, Cristina Teodosio, Pilar Giraldo, Manuel Giralt, M. Carmen Pérez, Mercedes Romero, Luis Perdiguer and Alberto Orfao

    Version of Record online : 5 DEC 2007, DOI: 10.1002/cyto.b.20390

  6. You have full text access to this OnlineOpen article
    Targeting BCL2 With BH3 Mimetics: Basic Science and Clinical Application of Venetoclax in Chronic Lymphocytic Leukemia and Related B Cell Malignancies

    Clinical Pharmacology & Therapeutics

    Volume 101, Issue 1, January 2017, Pages: 89–98, AW Roberts and DCS Huang

    Version of Record online : 26 NOV 2016, DOI: 10.1002/cpt.553

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    The BH3-mimetic ABT-737 inhibits allogeneic immune responses

    Transplant International

    Volume 24, Issue 7, July 2011, Pages: 722–732, Pietro E. Cippà, Anna K. Kraus, Ilka Edenhofer, Stephan Segerer, Jin Chen, Martin Hausmann, Yang Liu, Annick Guimezanes, Philip D. Bardwell, Rudolf P. Wüthrich and Thomas Fehr

    Version of Record online : 25 MAY 2011, DOI: 10.1111/j.1432-2277.2011.01272.x

  8. The clinical impact and molecular biology of del(17p) in multiple myeloma treated with conventional or thalidomide-based therapy

    Genes, Chromosomes and Cancer

    Volume 50, Issue 10, October 2011, Pages: 765–774, Kevin D. Boyd, Fiona M. Ross, William J. Tapper, Laura Chiecchio, GianPaolo Dagrada, Zoe J. Konn, David Gonzalez, Brian A. Walker, Sarah L. Hockley, Christopher P. Wardell, Walter M. Gregory, J. Anthony Child, Graham H. Jackson, Faith E. Davies, Gareth J. Morgan and on behalf of the NCRI Haematology Oncology Studies Group

    Version of Record online : 11 JUL 2011, DOI: 10.1002/gcc.20899

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    Controversial fluorescence in situ hybridization cytogenetic abnormalities in chronic lymphocytic leukaemia: new insights from a large cohort

    British Journal of Haematology

    Volume 170, Issue 5, September 2015, Pages: 694–703, Matthew S. Davids, Alexander Vartanov, Lillian Werner, Donna Neuberg, Paola Dal Cin and Jennifer R. Brown

    Version of Record online : 1 JUN 2015, DOI: 10.1111/bjh.13498

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    Chronic lymphocytic leukemia: 2013 update on diagnosis, risk stratification and treatment

    American Journal of Hematology

    Volume 88, Issue 9, September 2013, Pages: 803–816, Michael Hallek

    Version of Record online : 20 AUG 2013, DOI: 10.1002/ajh.23491

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    Role of p38 MAPK in enhanced human cancer cells killing by the combination of aspirin and ABT-737

    Journal of Cellular and Molecular Medicine

    Volume 19, Issue 2, February 2015, Pages: 408–417, Chong Zhang, Jing Shi, Shi-ying Mao, Ya-si Xu, Dan Zhang, Lin-yi Feng, Bo Zhang, You-you Yan, Si-cong Wang, Jian-ping Pan, You-ping Yang and Neng-ming Lin

    Version of Record online : 11 NOV 2014, DOI: 10.1111/jcmm.12461

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    Increased lymphocyte apoptosis in mouse models of colitis upon ABT-737 treatment is dependent upon BIM expression

    Clinical & Experimental Immunology

    Volume 181, Issue 2, August 2015, Pages: 343–356, C. Lutz, M. Mozaffari, V. Tosevski, M. Caj, P. Cippà, B. L. McRae, C. L. Graff, G. Rogler, M. Fried and M. Hausmann

    Version of Record online : 19 MAY 2015, DOI: 10.1111/cei.12635

  13. Incidence of 17p deletions and TP53 mutation in myelodysplastic syndrome and acute myeloid leukemia with 5q deletion

    Genes, Chromosomes and Cancer

    Volume 51, Issue 12, December 2012, Pages: 1086–1092, Amel Sebaa, Lionel Ades, Fanny Baran-Marzack, Marie-Joelle Mozziconacci, Dominique Penther, Sophie Dobbelstein, Aspasia Stamatoullas, Christian Récher, Thomas Prebet, Soraya Moulessehoul, Pierre Fenaux and Virginie Eclache

    Version of Record online : 30 AUG 2012, DOI: 10.1002/gcc.21993

  14. In vitro activity of 20 agents in different prognostic subgroups of chronic lymphocytic leukemia – rolipram and prednisolone active in cells from patients with poor prognosis

    European Journal of Haematology

    Volume 83, Issue 1, July 2009, Pages: 22–34, Elin Lindhagen, Maria Norberg, Meena Kanduri, Gerard Tobin, Laura Säisänen, Magnus Åberg, Mats G. Gustafsson, Christer Sundström, Richard Rosenquist and Anna Åleskog

    Version of Record online : 23 FEB 2009, DOI: 10.1111/j.1600-0609.2009.01248.x

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    ORAL PRESENTATIONS

    Hematological Oncology

    Volume 31, Issue S1, June 2013, Pages: 96–150,

    Version of Record online : 17 JUN 2013, DOI: 10.1002/hon.2057

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    Drp1 is dispensable for apoptotic cytochrome c release in primed MCF10A and fibroblast cells but affects Bcl-2 antagonist-induced respiratory changes

    British Journal of Pharmacology

    Volume 171, Issue 8, April 2014, Pages: 1988–1999, P Clerc, S X Ge, H Hwang, J Waddell, B A Roelofs, M Karbowski, H Sesaki and B M Polster

    Version of Record online : 28 MAR 2014, DOI: 10.1111/bph.12515

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    Targeting inhibitor of apoptosis proteins by Smac mimetic elicits cell death in poor prognostic subgroups of chronic lymphocytic leukemia

    International Journal of Cancer

    Volume 137, Issue 12, 15 December 2015, Pages: 2959–2970, Daniela Opel, Andrea Schnaiter, Dagmar Dodier, Marjana Jovanovic, Andreas Gerhardinger, Irina Idler, Daniel Mertens, Lars Bullinger, Stephan Stilgenbauer and Simone Fulda

    Version of Record online : 31 JUL 2015, DOI: 10.1002/ijc.29650

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    Synergistic induction of apoptosis by the Bcl-2 inhibitor ABT-737 and imatinib mesylate in gastrointestinal stromal tumor cells

    Molecular Oncology

    Volume 5, Issue 1, February 2011, Pages: 93–104, David Reynoso, Laura K. Nolden, Dan Yang, Sarah N. Dumont, Anthony P. Conley, Amaury G.P. Dumont, Kim Zhou, Anette Duensing, Jonathan C. Trent

    Version of Record online : 16 OCT 2010, DOI: 10.1016/j.molonc.2010.10.003

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    Inhibition of p38 MAPK enhances ABT-737-induced cell death in melanoma cell lines: novel regulation of PUMA

    Pigment Cell & Melanoma Research

    Volume 23, Issue 3, June 2010, Pages: 430–440, Angela M. Keuling, Susan E. Andrew and Victor A. Tron

    Version of Record online : 22 MAR 2010, DOI: 10.1111/j.1755-148X.2010.00698.x

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    ABT-737 is a useful component of combinatory chemotherapies for chronic myeloid leukaemias with diverse drug-resistance mechanisms

    British Journal of Haematology

    Volume 140, Issue 2, January 2008, Pages: 181–190, Junya Kuroda, Shinya Kimura, Michael Andreeff, Eishi Ashihara, Yuri Kamitsuji, Asumi Yokota, Eri Kawata, Miki Takeuchi, Ruriko Tanaka, Yoshihide Murotani, Yosuke Matsumoto, Hideo Tanaka, Andreas Strasser, Masafumi Taniwaki and Taira Maekawa

    Version of Record online : 20 NOV 2007, DOI: 10.1111/j.1365-2141.2007.06899.x