Search Results

There are 10861 results for: content related to: O 6 -methylguanine-DNA methyltransferase (MGMT) promoter methylation and low MGMT-encoded protein expression as prognostic markers in glioblastoma patients treated with biodegradable carmustine wafer implants after initial surgery followed by radiotherapy with concomitant and adjuvant temozolomide

  1. You have free access to this content
    Predictive impact of MGMT promoter methylation in glioblastoma of the elderly

    International Journal of Cancer

    Volume 131, Issue 6, 15 September 2012, Pages: 1342–1350, Guido Reifenberger, Bettina Hentschel, Jörg Felsberg, Gabriele Schackert, Matthias Simon, Oliver Schnell, Manfred Westphal, Wolfgang Wick, Torsten Pietsch, Markus Loeffler, Michael Weller and for the German Glioma Network

    Version of Record online : 11 JAN 2012, DOI: 10.1002/ijc.27385

  2. O6-methylguanine DNA methyltransferase repairs platinum-DNA adducts following cisplatin treatment and predicts prognoses of nasopharyngeal carcinoma

    International Journal of Cancer

    Volume 137, Issue 6, 15 September 2015, Pages: 1291–1305, Shang Hung Chen, Ching Chuan Kuo, Chien Feng Li, Chun Hei Antonio Cheung, Tsui Chun Tsou, Huai Chih Chiang, Yun Ning Yang, Shin Lun Chang, Li Ching Lin, Hsin Yi Pan, Kwang Yu Chang and Jang Yang Chang

    Version of Record online : 6 MAR 2015, DOI: 10.1002/ijc.29486

  3. You have free access to this content
    MGMT activity, promoter methylation and immunohistochemistry of pretreatment and recurrent malignant gliomas: a comparative study on astrocytoma and glioblastoma

    International Journal of Cancer

    Volume 127, Issue 9, 1 November 2010, Pages: 2106–2118, Markus Christmann, Georg Nagel, Sigrid Horn, Ulrike Krahn, Dorothee Wiewrodt, Clemens Sommer and Bernd Kaina

    Version of Record online : 3 FEB 2010, DOI: 10.1002/ijc.25229

  4. You have free access to this content
    MEK-ERK Signaling Dictates DNA-Repair Gene MGMT Expression and Temozolomide Resistance of Stem-Like Glioblastoma Cells via the MDM2-p53 Axis

    STEM CELLS

    Volume 29, Issue 12, December 2011, Pages: 1942–1951, Atsushi Sato, Jun Sunayama, Ken-ichiro Matsuda, Shizuka Seino, Kaori Suzuki, Eriko Watanabe, Ken Tachibana, Arata Tomiyama, Takamasa Kayama and Chifumi Kitanaka

    Version of Record online : 16 NOV 2011, DOI: 10.1002/stem.753

  5. Methylation status of the MGMT gene promoter fails to predict the clinical outcome of glioblastoma patients treated with ACNU plus cisplatin

    Neuropathology

    Volume 29, Issue 4, August 2009, Pages: 443–449, Chul-Kee Park, Sung-Hye Park, Se-Hoon Lee, Chae-Yong Kim, Dong-Wan Kim, Sun Ha Paek, Dong Gyu Kim, Dae Seog Heo, Il Han Kim and Hee-Won Jung

    Version of Record online : 6 JAN 2009, DOI: 10.1111/j.1440-1789.2008.00998.x

  6. You have free access to this content
    Activity of O6-methylguanine-DNA methyltransferase in relation to p53 status and therapeutic response in ovarian cancer

    International Journal of Cancer

    Volume 84, Issue 4, 20 August 1999, Pages: 388–395, Jan G. Hengstler, Berno Tanner, Lars Möller, Rolf Meinert and Bernd Kaina

    Version of Record online : 10 NOV 1999, DOI: 10.1002/(SICI)1097-0215(19990820)84:4<388::AID-IJC10>3.0.CO;2-3

  7. You have free access to this content
    Prognostic impact of O6-methylguanine-DNA methyltransferase silencing in patients with recurrent glioblastoma multiforme who undergo surgery and carmustine wafer implantation

    Cancer

    Volume 115, Issue 20, 15 October 2009, Pages: 4783–4794, Philippe Metellus, Bema Coulibaly, Isabelle Nanni, Frederic Fina, Nathalie Eudes, Roch Giorgi, Marylin Barrie, Olivier Chinot, Stephane Fuentes, Henry Dufour, L'houcine Ouafik and Dominique Figarella-Branger

    Version of Record online : 27 JUL 2009, DOI: 10.1002/cncr.24546

  8. Immunohistochemical profiles of IDH1, MGMT and P53: Practical significance for prognostication of patients with diffuse gliomas

    Neuropathology

    Volume 35, Issue 4, August 2015, Pages: 324–335, Ryosuke Ogura, Yoshihiro Tsukamoto, Manabu Natsumeda, Mizuho Isogawa, Hiroshi Aoki, Tsutomu Kobayashi, Seiichi Yoshida, Kouichiro Okamoto, Hitoshi Takahashi, Yukihiko Fujii and Akiyoshi Kakita

    Version of Record online : 6 MAY 2015, DOI: 10.1111/neup.12196

  9. You have free access to this content
    Comparative assessment of 5 methods (methylation-specific polymerase chain reaction, methylight, pyrosequencing, methylation-sensitive high-resolution melting, and immunohistochemistry) to analyze O6-methylguanine-DNA-methyltranferase in a series of 100 glioblastoma patients

    Cancer

    Volume 118, Issue 17, 1 September 2012, Pages: 4201–4211, Véronique Quillien, Audrey Lavenu, Lucie Karayan-Tapon, Catherine Carpentier, Marianne Labussière, Thierry Lesimple, Olivier Chinot, Michel Wager, Jérome Honnorat, Stephan Saikali, Frédéric Fina, Marc Sanson and Dominique Figarella-Branger

    Version of Record online : 31 JAN 2012, DOI: 10.1002/cncr.27392

  10. The Next Generation of Glioma Biomarkers: MGMT Methylation, BRAF Fusions and IDH1 Mutations

    Brain Pathology

    Volume 21, Issue 1, January 2011, Pages: 74–87, Andreas Von Deimling, Andrey Korshunov and Christian Hartmann

    Version of Record online : 3 DEC 2010, DOI: 10.1111/j.1750-3639.2010.00454.x

  11. You have free access to this content
    Repair of DNA lesion O6-methylguanine in hepatocellular carcinogenesis

    Journal of Hepato-Biliary-Pancreatic Surgery

    Volume 5, Issue 4, December 1998, Pages: 355–366, Glenn N. Major and Jane D. Collier

    Version of Record online : 1 DEC 1998, DOI: 10.1007/s005340050059

  12. Prognostic value of O-6-methylguanine-DNA methyltransferase loss in salivary gland carcinomas

    Head & Neck

    Volume 36, Issue 9, September 2014, Pages: 1258–1267, Asta Scesnaite, Sonata Jarmalaite, Maximillian Mueller, Abbas Agaimy, Johannes Zenk, Arndt Hartmann, Heinrich Iro, Brigitte Peters, Stephan Schwarz and Regine Schneider–Stock

    Version of Record online : 27 NOV 2013, DOI: 10.1002/hed.23445

  13. You have free access to this content
    MGMT CpG island is invariably methylated in adult astrocytic and oligodendroglial tumors with IDH1 or IDH2 mutations

    International Journal of Cancer

    Volume 131, Issue 5, 1 September 2012, Pages: 1104–1113, Shani Mulholland, Danita M. Pearson, Rifat A. Hamoudi, Deborah S. Malley, Caroline M. Smith, Jamie M.J. Weaver, David T.W. Jones, Sylvia Kocialkowski, L. Magnus Bäcklund, V. Peter Collins and Koichi Ichimura

    Version of Record online : 11 JAN 2012, DOI: 10.1002/ijc.26499

  14. Anti-O6-Methylguanine-Methyltransferase (MGMT) Immunohistochemistry in Glioblastoma Multiforme: Observer Variability and Lack of Association with Patient Survival Impede Its Use as Clinical Biomarker

    Brain Pathology

    Volume 18, Issue 4, October 2008, Pages: 520–532, Matthias Preusser, Robert Charles Janzer, Jörg Felsberg, Guido Reifenberger, Marie-France Hamou, Annie-Claire Diserens, Roger Stupp, Thierry Gorlia, Christine Marosi, Harald Heinzl, Johannes A Hainfellner and Monika Hegi

    Version of Record online : 8 APR 2008, DOI: 10.1111/j.1750-3639.2008.00153.x

  15. You have free access to this content
    Acquired resistance of melanoma cells to the antineoplastic agent fotemustine is caused by reactivation of the DNA repair gene mgmt

    International Journal of Cancer

    Volume 92, Issue 1, 1 April 2001, Pages: 123–129, Markus Christmann, Matthias Pick, Hermann Lage, Dirk Schadendorf and Bernd Kaina

    Version of Record online : 7 FEB 2001, DOI: 10.1002/1097-0215(200102)9999:9999<::AID-IJC1160>3.0.CO;2-V

  16. You have free access to this content
    Methylation of the O6-methylguanine-DNA methyltransferase promoter suppresses expression in mouse skin tumors and varies with the tumor induction protocol

    International Journal of Cancer

    Volume 118, Issue 3, 1 February 2006, Pages: 527–531, Rana Abdel-Fattah, Adam Glick, Ishtiaq Rehman, Patrick Maiberger and Henry Hennings

    Version of Record online : 10 AUG 2005, DOI: 10.1002/ijc.21316

  17. You have free access to this content
    O6-methylguanine DNA methyltransferase immunoexpression in nonfunctioning pituitary adenomas

    Cancer

    Volume 115, Issue 5, 1 March 2009, Pages: 1070–1080, Georg Widhalm, Stefan Wolfsberger, Matthias Preusser, Adelheid Woehrer, Mark R. Kotter, Thomas Czech, Christine Marosi and Engelbert Knosp

    Version of Record online : 20 JAN 2009, DOI: 10.1002/cncr.24053

  18. Low O6-methylguanine-DNA methyltransferase (MGMT) expression and response to temozolomide in aggressive pituitary tumours

    Clinical Endocrinology

    Volume 71, Issue 2, August 2009, Pages: 226–233, Ann I. McCormack, Kerrie L. McDonald, Anthony J. Gill, Susan J. Clark, Morton G. Burt, Kirsten A. Campbell, Wilton J. Braund, Nicholas S. Little, Raymond J. Cook, Ashley B. Grossman, Bruce G. Robinson and Roderick J. Clifton-Bligh

    Version of Record online : 3 DEC 2008, DOI: 10.1111/j.1365-2265.2008.03487.x

  19. You have free access to this content
    Methylation pattern of the O6-methylguanine-DNA methyltransferase gene in colon during progressive colorectal tumorigenesis

    International Journal of Cancer

    Volume 122, Issue 11, 1 June 2008, Pages: 2429–2436, Takeshi Nagasaka, Ajay Goel, Kenji Notohara, Takaomi Takahata, Hiromi Sasamoto, Takuyuki Uchida, Naoshi Nishida, Noriaki Tanaka, Clement Richard Boland and Nagahide Matsubara

    Version of Record online : 31 JAN 2008, DOI: 10.1002/ijc.23398

  20. You have free access to this content
    Tamoxifen accelerates proteasomal degradation of O6-methylguanine DNA methyltransferase in human cancer cells

    International Journal of Cancer

    Volume 121, Issue 10, 15 November 2007, Pages: 2293–2300, Ching-Chuan Kuo, Jin-Fen Liu, Her-Shyong Shiah, Li-Chen Ma and Jang-Yang Chang

    Version of Record online : 27 JUN 2007, DOI: 10.1002/ijc.22927